Harvard Catalyst Profiles

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Philip Arthur Cole, M.D.,Ph.D.


This page shows the publications Philip Cole has written about PTEN Phosphohydrolase.
Connection Strength

  1. Ubiquitin Ligase Activities of WWP1 Germline Variants K740N and N745S. Biochemistry. 2021 02 09; 60(5):357-364.
    View in: PubMed
    Score: 0.579
  2. Analysis of Site-Specific Phosphorylation of PTEN by Using Enzyme-Catalyzed Expressed Protein Ligation. Chembiochem. 2020 01 15; 21(1-2):64-68.
    View in: PubMed
    Score: 0.529
  3. Site-Specific Protein Labeling with N-Hydroxysuccinimide-Esters and the Analysis of Ubiquitin Ligase Mechanisms. J Am Chem Soc. 2018 08 01; 140(30):9374-9378.
    View in: PubMed
    Score: 0.487
  4. Protein Chemical Approaches to Understanding PTEN Lipid Phosphatase Regulation. Methods Enzymol. 2018; 607:405-422.
    View in: PubMed
    Score: 0.485
  5. Enzyme-catalyzed expressed protein ligation. Nat Methods. 2016 Nov; 13(11):925-927.
    View in: PubMed
    Score: 0.430
  6. Enzymatic Analysis of PTEN Ubiquitylation by WWP2 and NEDD4-1 E3 Ligases. Biochemistry. 2016 07 05; 55(26):3658-66.
    View in: PubMed
    Score: 0.422
  7. Molecular Features of Phosphatase and Tensin Homolog (PTEN) Regulation by C-terminal Phosphorylation. J Biol Chem. 2016 Jul 01; 291(27):14160-14169.
    View in: PubMed
    Score: 0.418
  8. Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis. Elife. 2013 Jul 09; 2:e00691.
    View in: PubMed
    Score: 0.344
  9. Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases. J Biol Chem. 2019 11 15; 294(46):17421-17436.
    View in: PubMed
    Score: 0.132
Connection Strength

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.