Harvard Catalyst Profiles

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Mark Cobbold, Ph.D., M.B.,Ch.B.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Grassberger C, Hong TS, Hato T, Yeap BY, Wo JY, Tracy M, Bortfeld T, Wolfgang JA, Eyler CE, Goyal L, Clark JW, Crane CH, Koay EJ, Cobbold M, DeLaney TF, Jain RK, Zhu AX, Duda DG. Differential Association Between Circulating Lymphocyte Populations With Outcome After Radiation Therapy in Subtypes of Liver Cancer. Int J Radiat Oncol Biol Phys. 2018 08 01; 101(5):1222-1225. PMID: 29859792.
    Citations:    Fields:    
  2. Aoki S, Cobbold M, Zhu AX, Duda DG. Can smart nanomedicine deliver effective targeted cytotoxic treatments to hepatocellular carcinomas while reducing the liver damage? Hepatology. 2018 03; 67(3):826-828. PMID: 29077214.
    Citations:    Fields:    Translation:Humans
  3. Mohammed F, Stones DH, Zarling AL, Willcox CR, Shabanowitz J, Cummings KL, Hunt DF, Cobbold M, Engelhard VH, Willcox BE. The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget. 2017 Aug 15; 8(33):54160-54172. PMID: 28903331.
    Citations:    Fields:    
  4. Wong GK, Heather JM, Barmettler S, Cobbold M. Immune dysregulation in immunodeficiency disorders: The role of T-cell receptor sequencing. J Autoimmun. 2017 Jun; 80:1-9. PMID: 28400082.
    Citations: 3     Fields:    Translation:HumansCells
  5. Malaker SA, Penny SA, Steadman LG, Myers PT, Loke JC, Raghavan M, Bai DL, Shabanowitz J, Hunt DF, Cobbold M. Identification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia. Cancer Immunol Res. 2017 05; 5(5):376-384. PMID: 28314751.
    Citations: 7     Fields:    Translation:HumansCells
  6. Campbell JP, Heaney JL, Shemar M, Baldwin D, Griffin AE, Oldridge E, Goodall M, Afzal Z, Plant T, Cobbold M, Jefferis R, Jacobs JF, Hand C, Drayson MT. Development of a rapid and quantitative lateral flow assay for the simultaneous measurement of serum ? and ? immunoglobulin free light chains (FLC): inception of a new near-patient FLC screening tool. Clin Chem Lab Med. 2017 Mar 01; 55(3):424-434. PMID: 27505089.
    Citations: 1     Fields:    Translation:Humans
  7. Ellis JD, Neil DA, Inston NG, Jenkinson E, Drayson MT, Hampson P, Shuttleworth SJ, Ready AR, Cobbold M. Inhibition of Histone Deacetylase 6 Reveals a Potent Immunosuppressant Effect in Models of Transplantation. Transplantation. 2016 Aug; 100(8):1667-74. PMID: 27222932.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  8. Wong GK, Millar D, Penny S, Heather JM, Mistry P, Buettner N, Bryon J, Huissoon AP, Cobbold M. Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency. J Immunol. 2016 09 01; 197(5):1642-9. PMID: 27481850.
    Citations:    Fields:    Translation:HumansCells
  9. Hitchcock JR, Cook CN, Bobat S, Ross EA, Flores-Langarica A, Lowe KL, Khan M, Dominguez-Medina CC, Lax S, Carvalho-Gaspar M, Hubscher S, Rainger GE, Cobbold M, Buckley CD, Mitchell TJ, Mitchell A, Jones ND, Van Rooijen N, Kirchhofer D, Henderson IR, Adams DH, Watson SP, Cunningham AF. Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets. J Clin Invest. 2015 Dec; 125(12):4429-46. PMID: 26571395.
    Citations: 9     Fields:    Translation:AnimalsCells
  10. Field M, Guy A, Ready AR, Cobbold M, Inston N. Hand-assisted Laparoscopic Donor Nephrectomy and Cytokine Changes. Transplant Proc. 2015 Nov; 47(9):2690-3. PMID: 26680073.
    Citations:    Fields:    Translation:Humans
  11. Taylor SL, Mason SK, Glinton SL, Cobbold M, Dehghani H. Accounting for filter bandwidth improves the quantitative accuracy of bioluminescence tomography. J Biomed Opt. 2015 Sep; 20(9):096001. PMID: 26325264.
    Citations:    Fields:    Translation:Animals
  12. Wernham AG, Shah F, Amel-Kashipaz R, Cobbold M, Scarisbrick J. Stage I mycosis fungoides: frequent association with a favourable prognosis but disease progression and disease-specific mortality may occur. Br J Dermatol. 2015 Nov; 173(5):1295-7. PMID: 26053896.
    Citations: 2     Fields:    Translation:Humans
  13. Abelin JG, Trantham PD, Penny SA, Patterson AM, Ward ST, Hildebrand WH, Cobbold M, Bai DL, Shabanowitz J, Hunt DF. Complementary IMAC enrichment methods for HLA-associated phosphopeptide identification by mass spectrometry. Nat Protoc. 2015 Sep; 10(9):1308-18. PMID: 26247297.
    Citations: 10     Fields:    
  14. Guy AJ, Nath J, Cobbold M, Ludwig C, Tennant DA, Inston NG, Ready AR. Metabolomic analysis of perfusate during hypothermic machine perfusion of human cadaveric kidneys. Transplantation. 2015 Apr; 99(4):754-9. PMID: 25222017.
    Citations: 5     Fields:    Translation:Humans
  15. Nath J, Guy A, Smith TB, Cobbold M, Inston NG, Hodson J, Tennant DA, Ludwig C, Ready AR. Metabolomic perfusate analysis during kidney machine perfusion: the pig provides an appropriate model for human studies. PLoS One. 2014; 9(12):e114818. PMID: 25502759.
    Citations: 2     Fields:    Translation:HumansAnimals
  16. Jamal-Hanjani M, Hackshaw A, Ngai Y, Shaw J, Dive C, Quezada S, Middleton G, de Bruin E, Le Quesne J, Shafi S, Falzon M, Horswell S, Blackhall F, Khan I, Janes S, Nicolson M, Lawrence D, Forster M, Fennell D, Lee SM, Lester J, Kerr K, Muller S, Iles N, Smith S, Murugaesu N, Mitter R, Salm M, Stuart A, Matthews N, Adams H, Ahmad T, Attanoos R, Bennett J, Birkbak NJ, Booton R, Brady G, Buchan K, Capitano A, Chetty M, Cobbold M, Crosbie P, Davies H, Denison A, Djearman M, Goldman J, Haswell T, Joseph L, Kornaszewska M, Krebs M, Langman G, MacKenzie M, Millar J, Morgan B, Naidu B, Nonaka D, Peggs K, Pritchard C, Remmen H, Rowan A, Shah R, Smith E, Summers Y, Taylor M, Veeriah S, Waller D, Wilcox B, Wilcox M, Woolhouse I, McGranahan N, Swanton C. Tracking genomic cancer evolution for precision medicine: the lung TRACERx study. PLoS Biol. 2014 Jul; 12(7):e1001906. PMID: 25003521.
    Citations: 37     Fields:    Translation:Humans
  17. Ross EA, Flores-Langarica A, Bobat S, Coughlan RE, Marshall JL, Hitchcock JR, Cook CN, Carvalho-Gaspar MM, Mitchell AM, Clarke M, Garcia P, Cobbold M, Mitchell TJ, Henderson IR, Jones ND, Anderson G, Buckley CD, Cunningham AF. Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function. Eur J Immunol. 2014 Aug; 44(8):2318-30. PMID: 24825601.
    Citations: 5     Fields:    Translation:AnimalsCells
  18. Field M, Dronavalli V, Mistry P, Drayson M, Ready A, Cobbold M, Inston N. Urinary biomarkers of acute kidney injury in deceased organ donors--kidney injury molecule-1 as an adjunct to predicting outcome. Clin Transplant. 2014 Jul; 28(7):808-15. PMID: 24801162.
    Citations: 3     Fields:    Translation:Humans
  19. Field M, Lowe D, Cobbold M, Higgins R, Briggs D, Inston N, Ready AR. The use of NGAL and IP-10 in the prediction of early acute rejection in highly sensitized patients following HLA-incompatible renal transplantation. Transpl Int. 2014 Apr; 27(4):362-70. PMID: 24438378.
    Citations: 2     Fields:    Translation:Humans
  20. Chakupurakal G, Onion D, Bonney S, Cobbold M, Mautner V, Moss P. HLA-peptide multimer selection of adenovirus-specific T cells for adoptive T-cell therapy. J Immunother. 2013 Oct; 36(8):423-31. PMID: 23994889.
    Citations: 4     Fields:    Translation:HumansCells
  21. Cobbold M, De La Peña H, Norris A, Polefrone JM, Qian J, English AM, Cummings KL, Penny S, Turner JE, Cottine J, Abelin JG, Malaker SA, Zarling AL, Huang HW, Goodyear O, Freeman SD, Shabanowitz J, Pratt G, Craddock C, Williams ME, Hunt DF, Engelhard VH. MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia. Sci Transl Med. 2013 Sep 18; 5(203):203ra125. PMID: 24048523.
    Citations: 40     Fields:    Translation:HumansCells
  22. Campbell JP, Cobbold M, Wang Y, Goodall M, Bonney SL, Chamba A, Birtwistle J, Plant T, Afzal Z, Jefferis R, Drayson MT. Development of a highly-sensitive multi-plex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine. J Immunol Methods. 2013 May 31; 391(1-2):1-13. PMID: 23388695.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  23. O'Shaughnessy CM, Micoli F, Gavini M, Goodall M, Cobbold M, Saul A, Maclennan CA. Purification of antibodies to O antigen of Salmonella Typhimurium from human serum by affinity chromatography. J Immunol Methods. 2013 Jan 31; 387(1-2):199-210. PMID: 23142459.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  24. Whitelegg AM, Birtwistle J, Richter A, Campbell JP, Turner JE, Ahmed TM, Giles LJ, Fellows M, Plant T, Ferraro AJ, Cobbold M, Drayson MT, MacLennan CA. Measurement of antibodies to pneumococcal, meningococcal and haemophilus polysaccharides, and tetanus and diphtheria toxoids using a 19-plexed assay. J Immunol Methods. 2012 Mar 30; 377(1-2):37-46. PMID: 22293629.
    Citations: 3     Fields:    Translation:Humans
  25. Khan N, Cobbold M, Cummerson J, Moss PA. Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions. Immunology. 2010 Dec; 131(4):537-48. PMID: 20722762.
    Citations: 10     Fields:    Translation:HumansCells
  26. MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, Kingsley RA, van Oosterhout JJ, Msefula CL, Mandala WL, Leyton DL, Marshall JL, Gondwe EN, Bobat S, López-Macías C, Doffinger R, Henderson IR, Zijlstra EE, Dougan G, Drayson MT, MacLennan IC, Molyneux ME. Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults. Science. 2010 Apr 23; 328(5977):508-12. PMID: 20413503.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  27. Chakupurakal G, Onion D, Cobbold M, Mautner V, Moss PA. Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin alpha4beta7. AIDS. 2010 Jan 16; 24(2):205-10. PMID: 19864932.
    Citations: 6     Fields:    Translation:HumansCells
  28. Nicholls S, Piper KP, Mohammed F, Dafforn TR, Tenzer S, Salim M, Mahendra P, Craddock C, van Endert P, Schild H, Cobbold M, Engelhard VH, Moss PA, Willcox BE. Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition. Proc Natl Acad Sci U S A. 2009 Mar 10; 106(10):3889-94. PMID: 19234124.
    Citations: 12     Fields:    Translation:HumansCells
  29. Mohammed F, Cobbold M, Zarling AL, Salim M, Barrett-Wilt GA, Shabanowitz J, Hunt DF, Engelhard VH, Willcox BE. Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self. Nat Immunol. 2008 Nov; 9(11):1236-43. PMID: 18836451.
    Citations: 31     Fields:    Translation:HumansCells
  30. Jones MA, Notta JK, Cobbold M, Palendira M, Hislop AD, Wilkie J, Snaith JS. Synthesis and ex vivo profiling of chemically modified cytomegalovirus CMVpp65 epitopes. J Pept Sci. 2008 Mar; 14(3):313-20. PMID: 17929331.
    Citations: 1     Fields:    Translation:Cells
  31. Amrolia PJ, Muccioli-Casadei G, Huls H, Adams S, Durett A, Gee A, Yvon E, Weiss H, Cobbold M, Gaspar HB, Rooney C, Kuehnle I, Ghetie V, Schindler J, Krance R, Heslop HE, Veys P, Vitetta E, Brenner MK. Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation. Blood. 2006 Sep 15; 108(6):1797-808. PMID: 16741253.
    Citations: 74     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  32. Cobbold M, Khan N, Pourgheysari B, Tauro S, McDonald D, Osman H, Assenmacher M, Billingham L, Steward C, Crawley C, Olavarria E, Goldman J, Chakraverty R, Mahendra P, Craddock C, Moss PA. Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers. J Exp Med. 2005 Aug 01; 202(3):379-86. PMID: 16061727.
    Citations: 145     Fields:    Translation:HumansCells
  33. Wiesner M, Zentz C, Hammer MH, Cobbold M, Kern F, Kolb HJ, Hammerschmidt W, Zeidler R, Moosmann A. Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines. Eur J Immunol. 2005 Jul; 35(7):2110-21. PMID: 15971271.
    Citations: 7     Fields:    Translation:HumansCells
  34. Khan N, Bruton R, Taylor GS, Cobbold M, Jones TR, Rickinson AB, Moss PA. Identification of cytomegalovirus-specific cytotoxic T lymphocytes in vitro is greatly enhanced by the use of recombinant virus lacking the US2 to US11 region or modified vaccinia virus Ankara expressing individual viral genes. J Virol. 2005 Mar; 79(5):2869-79. PMID: 15709006.
    Citations: 15     Fields:    Translation:HumansCells
  35. Khan N, Hislop A, Gudgeon N, Cobbold M, Khanna R, Nayak L, Rickinson AB, Moss PA. Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection. J Immunol. 2004 Dec 15; 173(12):7481-9. PMID: 15585874.
    Citations: 97     Fields:    Translation:HumansCells
  36. Moss PA, Cobbold M, Craddock C. The cellular immunotherapy of viral infection. Transfus Med. 2003 Dec; 13(6):405-15. PMID: 14651746.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  37. Moosmann A, Khan N, Cobbold M, Zentz C, Delecluse HJ, Hollweck G, Hislop AD, Blake NW, Croom-Carter D, Wollenberg B, Moss PA, Zeidler R, Rickinson AB, Hammerschmidt W. B cells immortalized by a mini-Epstein-Barr virus encoding a foreign antigen efficiently reactivate specific cytotoxic T cells. Blood. 2002 Sep 01; 100(5):1755-64. PMID: 12176897.
    Citations: 21     Fields:    Translation:HumansCells
  38. Khan N, Shariff N, Cobbold M, Bruton R, Ainsworth JA, Sinclair AJ, Nayak L, Moss PA. Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. J Immunol. 2002 Aug 15; 169(4):1984-92. PMID: 12165524.
    Citations: 196     Fields:    Translation:HumansCells
  39. Khan N, Cobbold M, Keenan R, Moss PA. Comparative analysis of CD8+ T cell responses against human cytomegalovirus proteins pp65 and immediate early 1 shows similarities in precursor frequency, oligoclonality, and phenotype. J Infect Dis. 2002 Apr 15; 185(8):1025-34. PMID: 11930311.
    Citations: 46     Fields:    Translation:HumansCells
  40. Cwynarski K, Craddock C, Cobbold M, Apperley J, Goldman J. Survival after bone-marrow transplantation. Lancet. 2002 Mar 09; 359(9309):887-8. PMID: 11897306.
    Citations:    Fields:    Translation:HumansCells
  41. Keenan RD, Ainsworth J, Khan N, Bruton R, Cobbold M, Assenmacher M, Milligan DW, Moss PA. Purification of cytomegalovirus-specific CD8 T cells from peripheral blood using HLA-peptide tetramers. Br J Haematol. 2001 Nov; 115(2):428-34. PMID: 11703346.
    Citations: 12     Fields:    Translation:HumansCells
  42. Cwynarski K, Ainsworth J, Cobbold M, Wagner S, Mahendra P, Apperley J, Goldman J, Craddock C, Moss PA. Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation. Blood. 2001 Mar 01; 97(5):1232-40. PMID: 11222365.
    Citations: 42     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.