Harvard Catalyst Profiles

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Giuseppe Coppotelli, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ross JM, Coppotelli G, Branca RM, Kim KM, Lehtiö J, Sinclair DA, Olson L. Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice. Aging Cell. 2019 12; 18(6):e13029. PMID: 31489782.
  2. Taglieri L, Nardo T, Vicinanza R, Ross JM, Scarpa S, Coppotelli G. Thyroid hormone regulates fibronectin expression through the activation of the hypoxia inducible factor 1. Biochem Biophys Res Commun. 2017 11 25; 493(3):1304-1310. PMID: 28974422.
    Citations: 1     Fields:    Translation:HumansCells
  3. Coppotelli G, Ross JM. Mitochondria in Ageing and Diseases: The Super Trouper of the Cell. Int J Mol Sci. 2016 May 11; 17(5). PMID: 27187361.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Ross JM, Olson L, Coppotelli G. Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin? Int J Mol Sci. 2015 Aug 17; 16(8):19458-76. PMID: 26287188.
    Citations: 13     Fields:    Translation:HumansCells
  5. Ross JM, Coppotelli G, Hoffer BJ, Olson L. Maternally transmitted mitochondrial DNA mutations can reduce lifespan. Sci Rep. 2014 Oct 09; 4:6569. PMID: 25299268.
    Citations: 8     Fields:    Translation:Animals
  6. Ross JM, Stewart JB, Hagström E, Brené S, Mourier A, Coppotelli G, Freyer C, Lagouge M, Hoffer BJ, Olson L, Larsson NG. Germline mitochondrial DNA mutations aggravate ageing and can impair brain development. Nature. 2013 Sep 19; 501(7467):412-5. PMID: 23965628.
    Citations: 73     Fields:    Translation:AnimalsCells
  7. Mughal N, Coppotelli G, Callegari S, Gastaldello S, Masucci MG. Interaction of gamma-herpesvirus genome maintenance proteins with cellular chromatin. PLoS One. 2013; 8(5):e62783. PMID: 23667520.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Vicinanza R, Coppotelli G, Malacrino C, Nardo T, Buchetti B, Lenti L, Celi FS, Scarpa S. Oxidized low-density lipoproteins impair endothelial function by inhibiting non-genomic action of thyroid hormone-mediated nitric oxide production in human endothelial cells. Thyroid. 2013 Feb; 23(2):231-8. PMID: 23072587.
    Citations: 6     Fields:    Translation:HumansCells
  9. Coppotelli G, Mughal N, Callegari S, Sompallae R, Caja L, Luijsterburg MS, Dantuma NP, Moustakas A, Masucci MG. The Epstein-Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins. Nucleic Acids Res. 2013 Mar 01; 41(5):2950-62. PMID: 23358825.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  10. Coppotelli G, Mughal N, Masucci MG. The Gly-Ala repeat modulates the interaction of Epstein-Barr virus nuclear antigen-1 with cellular chromatin. Biochem Biophys Res Commun. 2013 Feb 22; 431(4):706-11. PMID: 23348225.
    Citations: 1     Fields:    Translation:HumansCells
  11. Frisan T, Coppotelli G, Dryselius R, Masucci MG. Ubiquitin C-terminal hydrolase-L1 interacts with adhesion complexes and promotes cell migration, survival, and anchorage independent growth. FASEB J. 2012 Dec; 26(12):5060-70. PMID: 22932395.
    Citations: 11     Fields:    Translation:HumansCells
  12. Gastaldello S, Callegari S, Coppotelli G, Hildebrand S, Song M, Masucci MG. Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1. J Mol Cell Biol. 2012 Aug; 4(4):242-51. PMID: 22474075.
    Citations: 9     Fields:    Translation:HumansCells
  13. Martorelli D, Coppotelli G, Muraro E, Dolcetti R, Masucci MG. Remodeling of the epitope repertoire of a candidate idiotype vaccine by targeting to lysosomal degradation in dendritic cells. Cancer Immunol Immunother. 2012 Jun; 61(6):881-92. PMID: 22089857.
    Citations: 1     Fields:    Translation:HumansCells
  14. Coppotelli G, Mughal N, Marescotti D, Masucci MG. High avidity binding to DNA protects ubiquitylated substrates from proteasomal degradation. J Biol Chem. 2011 Jun 03; 286(22):19565-75. PMID: 21471195.
    Citations: 5     Fields:    Translation:HumansCells
  15. Cortes-Bratti X, Bassères E, Herrera-Rodriguez F, Botero-Kleiven S, Coppotelli G, Andersen JB, Masucci MG, Holmgren A, Chaves-Olarte E, Frisan T, Avila-Cariño J. Thioredoxin 80-activated-monocytes (TAMs) inhibit the replication of intracellular pathogens. PLoS One. 2011 Feb 18; 6(2):e16960. PMID: 21365006.
    Citations: 1     Fields:    Translation:HumansCells
  16. Ross JM, Öberg J, Brené S, Coppotelli G, Terzioglu M, Pernold K, Goiny M, Sitnikov R, Kehr J, Trifunovic A, Larsson NG, Hoffer BJ, Olson L. High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):20087-92. PMID: 21041631.
    Citations: 48     Fields:    Translation:AnimalsCells
  17. Bassères E, Coppotelli G, Pfirrmann T, Andersen JB, Masucci M, Frisan T. The ubiquitin C-terminal hydrolase UCH-L1 promotes bacterial invasion by altering the dynamics of the actin cytoskeleton. Cell Microbiol. 2010 Nov; 12(11):1622-33. PMID: 20608941.
    Citations: 9     Fields:    Translation:HumansCells
  18. Marescotti D, Destro F, Baldisserotto A, Marastoni M, Coppotelli G, Masucci M, Gavioli R. Characterization of an human leucocyte antigen A2-restricted Epstein-Barr virus nuclear antigen-1-derived cytotoxic T-lymphocyte epitope. Immunology. 2010 Mar; 129(3):386-95. PMID: 19922423.
    Citations: 4     Fields:    Translation:HumansCells
  19. Celi FS, Coppotelli G, Chidakel A, Kelly M, Brillante BA, Shawker T, Cherman N, Feuillan PP, Collins MT. The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome. J Clin Endocrinol Metab. 2008 Jun; 93(6):2383-9. PMID: 18349068.
    Citations: 12     Fields:    Translation:HumansCells
  20. Coppotelli G, Summers A, Chidakel A, Ross JM, Celi FS. Functional characterization of the 258 A/G (D2-ORFa-Gly3Asp) human type-2 deiodinase polymorphism: a naturally occurring variant increases the enzymatic activity by removing a putative repressor site in the 5' UTR of the gene. Thyroid. 2006 Jul; 16(7):625-32. PMID: 16889485.
    Citations: 9     Fields:    Translation:HumansCells
  21. Mentuccia D, Thomas MJ, Coppotelli G, Reinhart LJ, Mitchell BD, Shuldiner AR, Celi FS. The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish. Thyroid. 2005 Nov; 15(11):1223-7. PMID: 16356084.
    Citations: 15     Fields:    Translation:Humans
  22. Vasaturo F, Sallusti E, Gradilone A, Malacrino C, Nardo T, Avagnano G, Aglianò AM, Granato T, De Vincenzi B, Coppotelli G, Marzullo A, Soda G, Simonelli L, Modesti M, Scarpa S. Comparison of extracellular matrix and apoptotic markers between benign lesions and carcinomas in human breast. Int J Oncol. 2005 Oct; 27(4):1005-11. PMID: 16142317.
    Citations: 4     Fields:    Translation:HumansCells
  23. Vasaturo F, Malacrino C, Sallusti E, Coppotelli G, Birarelli P, Giuffrida A, Albonici L, Simonelli L, Modesti A, Modesti M, Scarpa S. Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells. Oncol Rep. 2005 Apr; 13(4):745-50. PMID: 15756452.
    Citations: 2     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.