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Nathan Hutzel Raines, M.D.


Icahn School of Medicine at Mount Sinai, New York, NYMD05/2015Medicine
Mount Sinai School of Medicine, New York, NYMPH05/2013Epidemiology and Biostatistics
Dartmouth College, Hanover NHBA06/2007Ecology and Evolutionary Biology
Beth Israel Deaconess Medical Center, Boston, MA06/2018Internal Medicine Residency
Beth Israel Deaconess Medical Center, Boston, MA12/2021Nephrology Fellowship
Doris Duke Physician Scientist Fellowship Recipient
Distinction in Research
George James Epidemiology Award
Outstanding MPH Thesis
2005 - 2006
Presidential Scholar
Gold Humanism Honor Society

My research is focused on exploring the pathophysiology underlying emerging and environmentally-mediated kidney diseases, and on using these physiologic understandings to develop and apply improved prevention and treatment regimens. In addition to my MD training, I hold a master’s degree in public health with a focus on epidemiology and biostatistics. Much of my work to date has revolved around Chronic Kidney Disease of Nontraditional Cause (CKDnt), alternatively called Mesoamerican Nephropathy (MeN). I was principal investigator and first author for one of the early prevalence studies on CKDnT in a hotspot region in Central America, and have since led research to determine the accuracy of kidney function estimating equations in CKDnT populations. My current work focuses on metabolic features of CKDnt, supported by a Doris Duke Physician Scientist Fellowship award, and more broadly on the application of "omics" methodologies to understand CKDnT pathophysiology. I am chairperson of the board of directors of La Isla Network, a nonprofit devoted to CKDnt research which is responsible for the creation and study of the first protocols designed to prevent the onset of CKDnt. I am also a founding member and current board co-chairperson for the Consortium on the Epidemic of Nephropathy in Central America and Mexico (CENCAM), the principal international society of researchers focused on the disease. Outside CKDnT, I study metabolic alterations and therapies in patients with COVID-19 associated acute kidney injury, as well as kidney injury, electrolytes, and acid base disorders in critically ill patients.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 2021082 (Nathan Raines) Jul 1, 2021 - Jun 30, 2024
    Doris Duke Foundation
    Niacinamide Adenine Dinucleotide (NAD+) Metabolism in Acute Kidney Injury (AKI) Events and Early Chronic Disease Among Individuals at Risk for Chronic Kidney Disease of Nontraditional Cause (CKDnT)
    Role: Principal Investigator
  2. T32DK007199 (POLLAK, MARTIN R.) Jul 1, 1977 - Jun 30, 2023
    Research Training in Nephrology
    Role: Co-Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.