Harvard Catalyst Profiles

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Jan Drugowitsch, Ph.D.


Building an optimal computational model of attention-modulated decision making
Soma Weiss, 01/08/18 - 04/01/19

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R34NS123819 (DRUGOWITSCH, JAN) Aug 15, 2021 - Jul 31, 2023
    The encoding of uncertainty in the Drosophila compass system
    Role: Principal Investigator
  2. R01AT011447 (GINTY, DAVID D) Sep 15, 2020 - Aug 31, 2023
    Spinal Cord Nociceptive Circuits that Deliver Outputs to the Brain to Initiate Pain
    Role: Co-Principal Investigator
  3. R01NS116753 (UCHIDA, NAOSHIGE) Apr 15, 2020 - May 31, 2023
    Distributional reinforcement learning in the brain.
    Role: Co-Principal Investigator
  4. R01MH115554 (DRUGOWITSCH, JAN) Aug 3, 2017 - May 31, 2021
    CRCNS: Leveraging decision-making variability to identify underlying computations
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weiss A, Chambon V, Lee JK, Drugowitsch J, Wyart V. Interacting with volatile environments stabilizes hidden-state inference and its brain signatures. Nat Commun. 2021 04 13; 12(1):2228. PMID: 33850124.
    Citations: 3     Fields:    Translation:Humans
  2. Jang AI, Sharma R, Drugowitsch J. Optimal policy for attention-modulated decisions explains human fixation behavior. Elife. 2021 03 26; 10. PMID: 33769284.
    Citations: 4     Fields:    Translation:Humans
  3. Yang S, Bill J, Drugowitsch J, Gershman SJ. Human visual motion perception shows hallmarks of Bayesian structural inference. Sci Rep. 2021 Feb 12; 11(1):3714. PMID: 33580096.
    Citations: 1     Fields:    
  4. Kafashan M, Jaffe AW, Chettih SN, Nogueira R, Arandia-Romero I, Harvey CD, Moreno-Bote R, Drugowitsch J. Scaling of sensory information in large neural populations shows signatures of information-limiting correlations. Nat Commun. 2021 01 20; 12(1):473. PMID: 33473113.
    Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
  5. Lowet AS, Zheng Q, Matias S, Drugowitsch J, Uchida N. Distributional Reinforcement Learning in the Brain. Trends Neurosci. 2020 12; 43(12):980-997. PMID: 33092893.
    Citations: 1     Fields:    Translation:HumansAnimals
  6. Bill J, Pailian H, Gershman SJ, Drugowitsch J. Hierarchical structure is employed by humans during visual motion perception. Proc Natl Acad Sci U S A. 2020 09 29; 117(39):24581-24589. PMID: 32938799.
    Citations: 2     Fields:    Translation:HumansCells
  7. Moreno-Bote R, Ramírez-Ruiz J, Drugowitsch J, Hayden BY. Heuristics and optimal solutions to the breadth-depth dilemma. Proc Natl Acad Sci U S A. 2020 08 18; 117(33):19799-19808. PMID: 32759219.
    Citations: 1     Fields:    Translation:Humans
  8. Neubarth NL, Emanuel AJ, Liu Y, Springel MW, Handler A, Zhang Q, Lehnert BP, Guo C, Orefice LL, Abdelaziz A, DeLisle MM, Iskols M, Rhyins J, Kim SJ, Cattel SJ, Regehr W, Harvey CD, Drugowitsch J, Ginty DD. Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception. Science. 2020 06 19; 368(6497). PMID: 32554568.
    Citations: 11     Fields:    Translation:AnimalsCells
  9. Mendonça AG, Drugowitsch J, Vicente MI, DeWitt EEJ, Pouget A, Mainen ZF. The impact of learning on perceptual decisions and its implication for speed-accuracy tradeoffs. Nat Commun. 2020 06 02; 11(1):2757. PMID: 32488065.
    Citations: 4     Fields:    Translation:Animals
  10. Xu C, Theisen E, Maloney R, Peng J, Santiago I, Yapp C, Werkhoven Z, Rumbaut E, Shum B, Tarnogorska D, Borycz J, Tan L, Courgeon M, Griffin T, Levin R, Meinertzhagen IA, de Bivort B, Drugowitsch J, Pecot MY. Control of Synaptic Specificity by Establishing a Relative Preference for Synaptic Partners. Neuron. 2020 04 22; 106(2):355. PMID: 32325060.
    Citations: 1     Fields:    
  11. Drugowitsch J, Mendonça AG, Mainen ZF, Pouget A. Learning optimal decisions with confidence. Proc Natl Acad Sci U S A. 2019 12 03; 116(49):24872-24880. PMID: 31732671.
    Citations: 7     Fields:    Translation:HumansCells
  12. Shan H, Moreno-Bote R, Drugowitsch J. Family of closed-form solutions for two-dimensional correlated diffusion processes. Phys Rev E. 2019 Sep; 100(3-1):032132. PMID: 31640022.
    Citations:    Fields:    
  13. Tajima S, Drugowitsch J, Patel N, Pouget A. Optimal policy for multi-alternative decisions. Nat Neurosci. 2019 09; 22(9):1503-1511. PMID: 31384015.
    Citations: 12     Fields:    Translation:HumansAnimals
  14. Xu C, Theisen E, Maloney R, Peng J, Santiago I, Yapp C, Werkhoven Z, Rumbaut E, Shum B, Tarnogorska D, Borycz J, Tan L, Courgeon M, Griffin T, Levin R, Meinertzhagen IA, de Bivort B, Drugowitsch J, Pecot MY. Control of Synaptic Specificity by Establishing a Relative Preference for Synaptic Partners. Neuron. 2019 09 04; 103(5):865-877.e7. PMID: 31300277.
    Citations: 7     Fields:    Translation:AnimalsCells
  15. Rouault M, Drugowitsch J, Koechlin E. Prefrontal mechanisms combining rewards and beliefs in human decision-making. Nat Commun. 2019 01 17; 10(1):301. PMID: 30655534.
    Citations: 6     Fields:    Translation:Humans
  16. Nogueira R, Abolafia JM, Drugowitsch J, Balaguer-Ballester E, Sanchez-Vives MV, Moreno-Bote R. Lateral orbitofrontal cortex anticipates choices and integrates prior with current information. Nat Commun. 2017 03 24; 8:14823. PMID: 28337990.
    Citations: 28     Fields:    Translation:AnimalsCells
  17. Drugowitsch J, Wyart V, Devauchelle AD, Koechlin E. Computational Precision of Mental Inference as Critical Source of Human Choice Suboptimality. Neuron. 2016 Dec 21; 92(6):1398-1411. PMID: 27916454.
    Citations: 43     Fields:    Translation:Humans
  18. Tajima S, Drugowitsch J, Pouget A. Optimal policy for value-based decision-making. Nat Commun. 2016 08 18; 7:12400. PMID: 27535638.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  19. Drugowitsch J. Becoming Confident in the Statistical Nature of Human Confidence Judgments. Neuron. 2016 05 04; 90(3):425-7. PMID: 27151633.
    Citations: 3     Fields:    Translation:HumansAnimals
  20. Pouget A, Drugowitsch J, Kepecs A. Confidence and certainty: distinct probabilistic quantities for different goals. Nat Neurosci. 2016 Mar; 19(3):366-74. PMID: 26906503.
    Citations: 93     Fields:    Translation:HumansAnimals
  21. Arandia-Romero I, Tanabe S, Drugowitsch J, Kohn A, Moreno-Bote R. Multiplicative and Additive Modulation of Neuronal Tuning with Population Activity Affects Encoded Information. Neuron. 2016 Mar 16; 89(6):1305-1316. PMID: 26924437.
    Citations: 23     Fields:    Translation:AnimalsCells
  22. Drugowitsch J. Fast and accurate Monte Carlo sampling of first-passage times from Wiener diffusion models. Sci Rep. 2016 Feb 11; 6:20490. PMID: 26864391.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  23. Moreno-Bote R, Drugowitsch J. Causal Inference and Explaining Away in a Spiking Network. Sci Rep. 2015 Dec 01; 5:17531. PMID: 26621426.
    Citations: 9     Fields:    Translation:HumansAnimals
  24. Drugowitsch J, DeAngelis GC, Angelaki DE, Pouget A. Tuning the speed-accuracy trade-off to maximize reward rate in multisensory decision-making. Elife. 2015 Jun 19; 4:e06678. PMID: 26090907.
    Citations: 16     Fields:    Translation:Humans
  25. Kneissler J, Drugowitsch J, Friston K, Butz MV. Simultaneous learning and filtering without delusions: a Bayes-optimal combination of Predictive Inference and Adaptive Filtering. Front Comput Neurosci. 2015; 9:47. PMID: 25983690.
    Citations: 2     
  26. Drugowitsch J, DeAngelis GC, Klier EM, Angelaki DE, Pouget A. Optimal multisensory decision-making in a reaction-time task. Elife. 2014 Jun 14; 3. PMID: 24929965.
    Citations: 32     Fields:    Translation:HumansCells
  27. Drugowitsch J, Moreno-Bote R, Pouget A. Relation between belief and performance in perceptual decision making. PLoS One. 2014; 9(5):e96511. PMID: 24816801.
    Citations: 27     Fields:    Translation:Humans
  28. Kneissler J, Stalph PO, Drugowitsch J, Butz MV. Filtering sensory information with XCSF: improving learning robustness and robot arm control performance. Evol Comput. 2014; 22(1):139-58. PMID: 23746295.
    Citations: 2     Fields:    
  29. Drugowitsch J, Pouget A. Probabilistic vs. non-probabilistic approaches to the neurobiology of perceptual decision-making. Curr Opin Neurobiol. 2012 Dec; 22(6):963-9. PMID: 22884815.
    Citations: 12     Fields:    Translation:HumansAnimals
  30. Drugowitsch J, Moreno-Bote R, Churchland AK, Shadlen MN, Pouget A. The cost of accumulating evidence in perceptual decision making. J Neurosci. 2012 Mar 14; 32(11):3612-28. PMID: 22423085.
    Citations: 152     Fields:    Translation:HumansAnimals
  31. Drugowitsch J, Pouget A. Quick thinking: perceiving in a tenth of a blink of an eye. Nat Neurosci. 2010 Mar; 13(3):279-80. PMID: 20177419.
    Citations: 1     Fields:    Translation:AnimalsCells
  32. Drugowitsch J, Barry AM. A formal framework and extensions for function approximation in learning classifier systems. Machine Learning. 2008; 70(1):45-88. View Publication.
  33. Drugowitsch J. Design and analysis of learning classifier systems: a probabilistic approach. 2008. View Publication.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.