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Ananth Karumanchi, M.B.,B.S.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Maric-Bilkan C, Abrahams VM, Arteaga SS, Bourjeily G, Conrad KP, Catov JM, Costantine MM, Cox B, Garovic V, George EM, Gernand AD, Jeyabalan A, Karumanchi SA, Laposky AD, Miodovnik M, Mitchell M, Pemberton VL, Reddy UM, Santillan MK, Tsigas E, Thornburg KLR, Ward K, Myatt L, Roberts JM. Research Recommendations From the National Institutes of Health Workshop on Predicting, Preventing, and Treating Preeclampsia. Hypertension. 2019 04; 73(4):757-766. PMID: 30686084.
    Citations: 7     Fields:    Translation:Humans
  2. Allegretti AS, Vela Parada X, Ortiz GA, Long J, Krinsky S, Zhao S, Fuchs BC, Sojoodi M, Zhang D, Karumanchi SA, Kalim S, Nigwekar SU, Thadhani RI, Parikh SM, Chung RT. Serum Angiopoietin-2 Predicts Mortality and Kidney Outcomes in Decompensated Cirrhosis. Hepatology. 2019 02; 69(2):729-741. PMID: 30141205.
    Citations: 6     Fields:    Translation:Humans
  3. Zhou HL, Zhang R, Anand P, Stomberski CT, Qian Z, Hausladen A, Wang L, Rhee EP, Parikh SM, Karumanchi SA, Stamler JS. Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury. Nature. 2019 01; 565(7737):96-100. PMID: 30487609.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  4. Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, Zsengeller ZK, Hennessy A, Karumanchi SA, Moore MJ, Khvorova A. RNAi modulation of placental sFLT1 for the treatment of preeclampsia. Nat Biotechnol. 2018 Nov 19. PMID: 30451990.
    Citations: 13     Fields:    
  5. Covarrubias AE, Lecarpentier E, Lo A, Salahuddin S, Gray KJ, Karumanchi SA, Zsengellér ZK. AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis. Am J Pathol. 2019 01; 189(1):104-114. PMID: 30315766.
    Citations: 7     Fields:    Translation:HumansCells
  6. Sircar M, Rosales IA, Selig MK, Xu D, Zsengeller ZK, Stillman IE, Libermann TA, Karumanchi SA, Thadhani RI. Complement 7 Is Up-Regulated in Human Early Diabetic Kidney Disease. Am J Pathol. 2018 10; 188(10):2147-2154. PMID: 30253844.
    Citations: 6     Fields:    Translation:HumansCells
  7. Palomaki GE, Martin JN, Karumanchi SA, Poon LC. Updates on Screening, Prevention, Treatment, and Genetic Markers for Preeclampsia. Clin Chem. 2018 12; 64(12):1684-1689. PMID: 30201802.
    Citations: 1     Fields:    Translation:Humans
  8. Prete A, Lo AS, Sadow PM, Bhasin SS, Antonello ZA, Vodopivec DM, Ullas S, Sims JN, Clohessy J, Dvorak AM, Sciuto T, Bhasin M, Murphy-Ullrich JE, Lawler J, Karumanchi SA, Nucera C. Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFß1 Axis. Clin Cancer Res. 2018 12 01; 24(23):6078-6097. PMID: 30076136.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  9. Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, DeWan AT, Triche EW, Saftlas AF, Hoh J, Bodian DL, Klein E, Huddleston KC, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Wilson ML, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R. Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1. Hypertension. 2018 08; 72(2):408-416. PMID: 29967039.
    Citations: 9     Fields:    Translation:Humans
  10. Brown MA, Magee LA, Kenny LC, Karumanchi SA, McCarthy FP, Saito S, Hall DR, Warren CE, Adoyi G, Ishaku S. Hypertensive Disorders of Pregnancy: ISSHP Classification, Diagnosis, and Management Recommendations for International Practice. Hypertension. 2018 07; 72(1):24-43. PMID: 29899139.
    Citations: 117     Fields:    Translation:Humans
  11. Tangren JS, Wan Md Adnan WAH, Powe CE, Ecker J, Bramham K, Hladunewich MA, Ankers E, Karumanchi SA, Thadhani R. Risk of Preeclampsia and Pregnancy Complications in Women With a History of Acute Kidney Injury. Hypertension. 2018 08; 72(2):451-459. PMID: 29915020.
    Citations: 6     Fields:    Translation:Humans
  12. Ciampa E, Li Y, Dillon S, Lecarpentier E, Sorabella L, Libermann TA, Karumanchi SA, Hess PE. Cerebrospinal Fluid Protein Changes in Preeclampsia. Hypertension. 2018 07; 72(1):219-226. PMID: 29844151.
    Citations: 3     Fields:    Translation:Humans
  13. Rana S, Salahuddin S, Mueller A, Berg AH, Thadhani RI, Karumanchi SA. Angiogenic biomarkers in triage and risk for preeclampsia with severe features. Pregnancy Hypertens. 2018 Jul; 13:100-106. PMID: 30177034.
    Citations: 1     Fields:    Translation:Humans
  14. Brown MA, Magee LA, Kenny LC, Karumanchi SA, McCarthy FP, Saito S, Hall DR, Warren CE, Adoyi G, Ishaku S. The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens. 2018 Jul; 13:291-310. PMID: 29803330.
    Citations: 71     Fields:    Translation:Humans
  15. Lecarpentier E, Karumanchi SA, Haddad B. In Reply. Obstet Gynecol. 2018 05; 131(5):936. PMID: 29683899.
    Citations:    Fields:    Translation:Humans
  16. Karumanchi SA. Angiogenic factors in pre-eclampsia: implications for clinical practice. BJOG. 2018 10; 125(11):1396. PMID: 29473285.
    Citations: 4     Fields:    Translation:Humans
  17. Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, Moore MJ, Aronin N, Khvorova A. Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo. Nucleic Acids Res. 2018 03 16; 46(5):2185-2196. PMID: 29432571.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  18. Tangren JS, Powe CE, Ecker J, Bramham K, Ankers E, Karumanchi SA, Thadhani R. Metabolic and Hypertensive Complications of Pregnancy in Women with Nephrolithiasis. Clin J Am Soc Nephrol. 2018 04 06; 13(4):612-619. PMID: 29472305.
    Citations: 1     Fields:    Translation:Humans
  19. Kim SK, McCurley AT, DuPont JJ, Aronovitz M, Moss ME, Stillman IE, Karumanchi SA, Christou DD, Jaffe IZ. Smooth Muscle Cell-Mineralocorticoid Receptor as a Mediator of Cardiovascular Stiffness With Aging. Hypertension. 2018 04; 71(4):609-621. PMID: 29463624.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  20. Oe Y, Ko M, Fushima T, Sato E, Karumanchi SA, Sato H, Sugawara J, Ito S, Takahashi N. Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase. Sci Rep. 2018 01 08; 8(1):102. PMID: 29311569.
    Citations: 5     Fields:    Translation:Animals
  21. Lecarpentier E, Gris JC, Cochery-Nouvellon E, Mercier E, Touboul C, Thadhani R, Karumanchi SA, Haddad B. Angiogenic Factor Profiles in Pregnant Women With a History of Early-Onset Severe Preeclampsia Receiving Low-Molecular-Weight Heparin Prophylaxis. Obstet Gynecol. 2018 01; 131(1):63-69. PMID: 29215518.
    Citations: 1     Fields:    Translation:Humans
  22. Gray KJ, Saxena R, Karumanchi SA. Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis. Am J Obstet Gynecol. 2018 02; 218(2):211-218. PMID: 29138037.
    Citations: 10     Fields:    Translation:Humans
  23. Antonello ZA, Hsu N, Bhasin M, Roti G, Joshi M, Van Hummelen P, Ye E, Lo AS, Karumanchi SA, Bryke CR, Nucera C. Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E. Oncotarget. 2017 Oct 17; 8(49):84743-84760. PMID: 29156680.
    Citations: 14     Fields:    
  24. Ashar-Patel A, Kaymaz Y, Rajakumar A, Bailey JA, Karumanchi SA, Moore MJ. FLT1 and transcriptome-wide polyadenylation site (PAS) analysis in preeclampsia. Sci Rep. 2017 09 22; 7(1):12139. PMID: 28939845.
    Citations: 12     Fields:    Translation:HumansCells
  25. Griessenauer CJ, Chua MH, Hanafy KA, Baffour YT, Chen R, LeBlanc RH, Patel AS, Salem M, Karumanchi SA, Xu D, Thadhani R, Ogilvy CS, Thomas AJ. Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) and Risk of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage. World Neurosurg. 2017 Dec; 108:84-89. PMID: 28867315.
    Citations: 1     Fields:    Translation:Humans
  26. Khedkar SA, Samad MA, Choudhury S, Lee JY, Zhang D, Thadhani RI, Karumanchi SA, Rigby AC, Kang PM. Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and ??devoid of Hypercalcemia. Sci Rep. 2017 08 16; 7(1):8427. PMID: 28814738.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  27. Skurnik G, Hurwitz S, McElrath TF, Tsen LC, Duey S, Saxena AR, Karumanchi A, Rich-Edwards JW, Seely EW. Labor therapeutics and BMI as risk factors for postpartum preeclampsia: A case-control study. Pregnancy Hypertens. 2017 Oct; 10:177-181. PMID: 29153674.
    Citations: 3     Fields:    Translation:Humans
  28. Berg AH, Bhan I, Powe C, Karumanchi SA, Xu D, Thadhani RI. Acute Homeostatic Changes Following Vitamin D2 Supplementation. J Endocr Soc. 2017 Sep 01; 1(9):1135-1149. PMID: 29264568.
    Citations: 1     
  29. Hecht JL, Ordi J, Carrilho C, Ismail MR, Zsengeller ZK, Karumanchi SA, Rosen S. The pathology of eclampsia: An autopsy series. Hypertens Pregnancy. 2017 Aug; 36(3):259-268. PMID: 28678644.
    Citations: 2     Fields:    Translation:Humans
  30. Jim B, Karumanchi SA. Preeclampsia: Pathogenesis, Prevention, and Long-Term Complications. Semin Nephrol. 2017 07; 37(4):386-397. PMID: 28711078.
    Citations: 32     Fields:    Translation:Humans
  31. Shainker SA, Dannheim K, Gerson KD, Neo D, Zsengeller ZK, Pernicone E, Karumanchi SA, Hacker MR, Hecht JL. Down-regulation of soluble fms-like tyrosine kinase 1 expression in invasive placentation. Arch Gynecol Obstet. 2017 Aug; 296(2):257-262. PMID: 28631072.
    Citations: 2     Fields:    Translation:HumansCells
  32. Nezu M, Souma T, Yu L, Sekine H, Takahashi N, Wei AZ, Ito S, Fukamizu A, Zsengeller ZK, Nakamura T, Hozawa A, Karumanchi SA, Suzuki N, Yamamoto M. Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes. Sci Signal. 2017 May 16; 10(479). PMID: 28512147.
    Citations: 10     Fields:    Translation:HumansAnimals
  33. Wang AM, Karumanchi SA. Offspring Cardiovascular Disease in Preeclampsia: Nature Versus Nurture? Hypertension. 2017 04; 69(4):589-590. PMID: 28223476.
    Citations: 2     Fields:    Translation:Humans
  34. Spiel M, Salahuddin S, Pernicone E, Zsengeller Z, Wang A, Modest AM, Karumanchi SA, Hecht JL. Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes. Placenta. 2017 04; 52:10-16. PMID: 28454690.
    Citations: 3     Fields:    Translation:HumansCells
  35. Korkes HA, De Oliveira L, Sass N, Salahuddin S, Karumanchi SA, Rajakumar A. Relationship between hypoxia and downstream pathogenic pathways in preeclampsia. Hypertens Pregnancy. 2017 May; 36(2):145-150. PMID: 28067578.
    Citations: 9     Fields:    Translation:Humans
  36. Tangren JS, Powe CE, Ankers E, Ecker J, Bramham K, Hladunewich MA, Karumanchi SA, Thadhani R. Pregnancy Outcomes after Clinical Recovery from AKI. J Am Soc Nephrol. 2017 May; 28(5):1566-1574. PMID: 28008002.
    Citations: 13     Fields:    Translation:Humans
  37. Erpenbeck L, Chowdhury CS, Zsengellér ZK, Gallant M, Burke SD, Cifuni S, Hahn S, Wagner DD, Karumanchi SA. PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model. Biol Reprod. 2016 12; 95(6):132. PMID: 28007693.
    Citations: 8     Fields:    Translation:AnimalsCells
  38. Li F, Fushima T, Oyanagi G, Townley-Tilson HW, Sato E, Nakada H, Oe Y, Hagaman JR, Wilder J, Li M, Sekimoto A, Saigusa D, Sato H, Ito S, Jennette JC, Maeda N, Karumanchi SA, Smithies O, Takahashi N. Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):13450-13455. PMID: 27821757.
    Citations: 11     Fields:    Translation:Animals
  39. Chen CW, Drechsler C, Suntharalingam P, Karumanchi SA, Wanner C, Berg AH. High Glycated Albumin and Mortality in Persons with Diabetes Mellitus on Hemodialysis. Clin Chem. 2017 Feb; 63(2):477-485. PMID: 27737895.
    Citations: 10     Fields:    Translation:Humans
  40. Cavalli RC, Cerdeira AS, Pernicone E, Korkes HA, Burke SD, Rajakumar A, Thadhani RI, Roberts DJ, Bhasin M, Karumanchi SA, Kopcow HD. Induced Human Decidual NK-Like Cells Improve Utero-Placental Perfusion in Mice. PLoS One. 2016; 11(10):e0164353. PMID: 27736914.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  41. Allegretti AS, Ortiz G, Kalim S, Wibecan J, Zhang D, Shan HY, Xu D, Chung RT, Karumanchi SA, Thadhani RI. Siglec-7 as a Novel Biomarker to Predict Mortality in Decompensated Cirrhosis and Acute Kidney Injury. Dig Dis Sci. 2016 12; 61(12):3609-3620. PMID: 27655105.
    Citations: 1     Fields:    Translation:Humans
  42. Kalim S, Trottier CA, Wenger JB, Wibecan J, Ahmed R, Ankers E, Karumanchi SA, Thadhani R, Berg AH. Longitudinal Changes in Protein Carbamylation and Mortality Risk after Initiation of Hemodialysis. Clin J Am Soc Nephrol. 2016 10 07; 11(10):1809-1816. PMID: 27445162.
    Citations: 6     Fields:    Translation:HumansCells
  43. Nadkarni NA, Rajakumar A, Mokhashi N, Burke SD, Rana S, Salahuddin S, Dang Q, Thadhani R, Krishnan R, Stossel TP, Karumanchi SA. Gelsolin is an endogenous inhibitor of syncytiotrophoblast extracellular vesicle shedding in pregnancy. Pregnancy Hypertens. 2016 Oct; 6(4):333-339. PMID: 27939478.
    Citations: 2     Fields:    Translation:HumansCells
  44. Falk RT, Staff AC, Bradwin G, Karumanchi SA, Troisi R. A prospective study of angiogenic markers and postmenopausal breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Causes Control. 2016 08; 27(8):1009-17. PMID: 27357932.
    Citations:    Fields:    Translation:Humans
  45. Perl J, Kalim S, Wald R, Goldstein MB, Yan AT, Noori N, Kiaii M, Wenger J, Chan C, Thadhani RI, Karumanchi SA, Berg AH. Reduction of carbamylated albumin by extended hemodialysis. Hemodial Int. 2016 10; 20(4):510-521. PMID: 27329430.
    Citations: 3     Fields:    Translation:Humans
  46. Oh YS, Appel LJ, Galis ZS, Hafler DA, He J, Hernandez AL, Joe B, Karumanchi SA, Maric-Bilkan C, Mattson D, Mehta NN, Randolph G, Ryan M, Sandberg K, Titze J, Tolunay E, Toney GM, Harrison DG. National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness: Building on the Current Scientific Evidence. Hypertension. 2016 08; 68(2):281-8. PMID: 27324228.
    Citations: 24     Fields:    Translation:Humans
  47. Andersen LB, Dechend R, Karumanchi SA, Nielsen J, Joergensen JS, Jensen TK, Christesen HT. Early pregnancy angiogenic markers and spontaneous abortion: an Odense Child Cohort study. Am J Obstet Gynecol. 2016 Nov; 215(5):594.e1-594.e11. PMID: 27287686.
    Citations: 4     Fields:    Translation:Humans
  48. Burke SD, Zsengellér ZK, Khankin EV, Lo AS, Rajakumar A, DuPont JJ, McCurley A, Moss ME, Zhang D, Clark CD, Wang A, Seely EW, Kang PM, Stillman IE, Jaffe IZ, Karumanchi SA. Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia. J Clin Invest. 2016 07 01; 126(7):2561-74. PMID: 27270170.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  49. Young BC, Karumanchi SA. Toward a Better Diagnosis for Preeclampsia. Clin Chem. 2016 07; 62(7):913-5. PMID: 27159999.
    Citations:    Fields:    Translation:Humans
  50. Maski MR, Thomas RJ, Karumanchi SA, Parikh SM. Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Patients with Obstructive Sleep Apnea. PLoS One. 2016; 11(5):e0154503. PMID: 27149121.
    Citations: 2     Fields:    Translation:Humans
  51. Duffy JM, van 't Hooft J, Gale C, Brown M, Grobman W, Fitzpatrick R, Karumanchi SA, Lucas N, Magee L, Mol B, Stark M, Thangaratinam S, Wilson M, von Dadelszen P, Williamson P, Khan KS, Ziebland S, McManus RJ. A protocol for developing, disseminating, and implementing a core outcome set for pre-eclampsia. Pregnancy Hypertens. 2016 Oct; 6(4):274-278. PMID: 27939467.
    Citations: 11     Fields:    Translation:Humans
  52. Shahul S, Medvedofsky D, Wenger JB, Nizamuddin J, Brown SM, Bajracharya S, Salahuddin S, Thadhani R, Mueller A, Tung A, Lang RM, Arany Z, Talmor D, Karumanchi SA, Rana S. Circulating Antiangiogenic Factors and Myocardial Dysfunction in Hypertensive Disorders of Pregnancy. Hypertension. 2016 06; 67(6):1273-80. PMID: 27113052.
    Citations: 10     Fields:    Translation:Humans
  53. Makris A, Yeung KR, Lim SM, Sunderland N, Heffernan S, Thompson JF, Iliopoulos J, Killingsworth MC, Yong J, Xu B, Ogle RF, Thadhani R, Karumanchi SA, Hennessy A. Placental Growth Factor Reduces Blood Pressure in a Uteroplacental Ischemia Model of Preeclampsia in Nonhuman Primates. Hypertension. 2016 06; 67(6):1263-72. PMID: 27091894.
    Citations: 24     Fields:    Translation:Animals
  54. Karumanchi SA. Angiogenic Factors in Preeclampsia: From Diagnosis to Therapy. Hypertension. 2016 06; 67(6):1072-9. PMID: 27067718.
    Citations: 28     Fields:    Translation:HumansAnimals
  55. Hecht JL, Zsengeller ZK, Spiel M, Karumanchi SA, Rosen S. Revisiting decidual vasculopathy. Placenta. 2016 Jun; 42:37-43. PMID: 27238712.
    Citations: 3     Fields:    Translation:Humans
  56. Salahuddin S, Wenger JB, Zhang D, Thadhani R, Karumanchi SA, Rana S. KRYPTOR-automated angiogenic factor assays and risk of preeclampsia-related adverse outcomes. Hypertens Pregnancy. 2016 Aug; 35(3):330-45. PMID: 27028795.
    Citations: 3     Fields:    Translation:Humans
  57. Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM. PGC1a drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature. 2016 Mar 24; 531(7595):528-32. PMID: 26982719.
    Citations: 115     Fields:    Translation:HumansAnimalsCells
  58. Tonelli M, Karumanchi SA, Thadhani R. Epidemiology and Mechanisms of Uremia-Related Cardiovascular Disease. Circulation. 2016 Feb 02; 133(5):518-36. PMID: 26831434.
    Citations: 33     Fields:    Translation:Humans
  59. Spradley FT, Tan AY, Joo WS, Daniels G, Kussie P, Karumanchi SA, Granger JP. Placental Growth Factor Administration Abolishes Placental Ischemia-Induced Hypertension. Hypertension. 2016 Apr; 67(4):740-7. PMID: 26831193.
    Citations: 36     Fields:    Translation:HumansAnimals