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Bradley Merritt Wertheim, M.D.

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Lafayette College, Easton, PABS05/2007Biochemistry
Harvard Medical School, Boston, MAMD05/2011
Massachusetts General Hospital, Boston, MA06/2014Internal Medicine Residency
Brigham and Women's Hospital, Boston, MA06/2016Burke Advanced Fellowship in Pulmonary Heart Disease
Brigham and Women's Hospital, Boston, MA06/2017Pulmonary and Critical Care Medicine Fellowship
Hearst Young Investigator Award
Basic Science Fellowship Award
2008 - 2010
Howard G. Lapsley Memorial Scholarship
2003 - 2007
Trustee Scholarship
Merck Index Award
Dr. and Mrs. David Schwimmer '35 Prize in Honor of Theodore A. Distler
Phi Lambda Upsilon, Chemistry Honor Society
Sigma Xi, Research Honor Society
2004 - 2006
Excel Scholarship

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08HL151976 (WERTHEIM, BRADLEY) Jul 1, 2020 - Jun 30, 2025
    Ubiquitination and Endothelial Fibrosis in Early Pulmonary Arterial Hypertension
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wertheim BM. New Tricks for an Old Drug: Prostacyclins and Right Ventricular Contractility in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022 07 01; 206(1):12-13. PMID: 35536731.
    Citations:    Fields:    Translation:Humans
  2. Alba GA, Samokhin AO, Wang RS, Wertheim BM, Haley KJ, Padera RF, Vargas SO, Rosas IO, Hariri LP, Shih A, Thompson BT, Mitchell RN, Maron BA. Pulmonary endothelial NEDD9 and the prothrombotic pathophenotype of acute respiratory distress syndrome due to SARS-CoV-2 infection. Pulm Circ. 2022 Apr; 12(2):e12071. PMID: 35599981; PMCID: PMC9111030.
    Citations: 2     
  3. Alba GA, Samokhin AO, Wang RS, Zhang YY, Wertheim BM, Arons E, Greenfield EA, Lundberg Slingsby MH, Ceglowski JR, Haley KJ, Bowman FP, Yu YR, Haney JC, Eng G, Mitchell RN, Sheets A, Vargas SO, Seo S, Channick RN, Leary PJ, Rajagopal S, Loscalzo J, Battinelli EM, Maron BA. NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. Am J Respir Crit Care Med. 2021 06 15; 203(12):1533-1545. PMID: 33523764; PMCID: PMC8483217.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  4. Wertheim BM, Kapur S, Lakdawala NK, Carroll TL. Hypertrophic Cardiomyopathy as an Unexpected Mimic of Inducible Laryngeal Obstruction: The Case for Cardiopulmonary Exercise Testing in Otolaryngology. J Voice. 2020 Dec 30. PMID: 33388230; PMCID: PMC8243399.
    Citations:    Fields:    
  5. Charles EJ, Wertheim BM. Commentary: Small packages, big questions: Mitochondrial transplantation in a preclinical model of pulmonary arterial hypertension. J Thorac Cardiovasc Surg. 2022 05; 163(5):e379-e380. PMID: 33229181.
    Citations:    Fields:    Translation:HumansCells
  6. Maron BA, Brittain EL, Hess E, Waldo SW, Barón AE, Huang S, Goldstein RH, Assad T, Wertheim BM, Alba GA, Leopold JA, Olschewski H, Galiè N, Simonneau G, Kovacs G, Tedford RJ, Humbert M, Choudhary G. Pulmonary vascular resistance and clinical outcomes in patients with pulmonary hypertension: a retrospective cohort study. Lancet Respir Med. 2020 09; 8(9):873-884. PMID: 32730752; PMCID: PMC8219057.
    Citations: 25     Fields:    Translation:Humans
  7. Schimmel K, Jung M, Foinquinos A, José GS, Beaumont J, Bock K, Grote-Levi L, Xiao K, Bär C, Pfanne A, Just A, Zimmer K, Ngoy S, López B, Ravassa S, Samolovac S, Janssen-Peters H, Remke J, Scherf K, Dangwal S, Piccoli MT, Kleemiss F, Kreutzer FP, Kenneweg F, Leonardy J, Hobuß L, Santer L, Do QT, Geffers R, Braesen JH, Schmitz J, Brandenberger C, Müller DN, Wilck N, Kaever V, Bähre H, Batkai S, Fiedler J, Alexander KM, Wertheim BM, Fisch S, Liao R, Diez J, González A, Thum T. Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction. Circulation. 2020 03 03; 141(9):751-767. PMID: 31948273; PMCID: PMC7050799.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  8. Samokhin AO, Hsu S, Yu PB, Waxman AB, Alba GA, Wertheim BM, Hopkins CD, Bowman F, Channick RN, Nikolic I, Faria-Urbina M, Hassoun PM, Leopold JA, Tedford RJ, Ventetuolo CE, Leary PJ, Maron BA. Circulating NEDD9 is increased in pulmonary arterial hypertension: A multicenter, retrospective analysis. J Heart Lung Transplant. 2020 04; 39(4):289-299. PMID: 31952977.
    Citations: 8     Fields:    Translation:HumansCells
  9. Maron BA, Wertheim BM. Toward Early Diagnosis of Pulmonary Hypertension: Lessons From Oz. J Am Coll Cardiol. 2019 06 04; 73(21):2673-2675. PMID: 31146811; PMCID: PMC6747056.
    Citations:    Fields:    Translation:Humans
  10. Wertheim BM, Lin YD, Zhang YY, Samokhin AO, Alba GA, Arons E, Yu PB, Maron BA. Isolating pulmonary microvascular endothelial cells ex vivo: Implications for pulmonary arterial hypertension, and a caution on the use of commercial biomaterials. PLoS One. 2019; 14(2):e0211909. PMID: 30811450; PMCID: PMC6392245.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  11. Opotowsky AR, Wertheim BM, Tedford RJ. Not Quite Chronic Thromboembolic Pulmonary Hypertension But More Than a SOB Story. JACC Cardiovasc Imaging. 2019 08; 12(8 Pt 1):1457-1459. PMID: 30219406.
    Citations:    Fields:    Translation:Humans
  12. Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA. NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension. Sci Transl Med. 2018 06 13; 10(445). PMID: 29899023.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  13. Maron BA, Wertheim BM, Gladwin MT. Under Pressure to Clarify Pulmonary Hypertension Clinical Risk. Am J Respir Crit Care Med. 2018 02 15; 197(4):423-426. PMID: 29216444; PMCID: PMC5821912.
    Citations: 5     Fields:    Translation:Humans
  14. Oldham WM, Oliveira RKF, Wang RS, Opotowsky AR, Rubins DM, Hainer J, Wertheim BM, Alba GA, Choudhary G, Tornyos A, MacRae CA, Loscalzo J, Leopold JA, Waxman AB, Olschewski H, Kovacs G, Systrom DM, Maron BA. Network Analysis to Risk Stratify Patients With Exercise Intolerance. Circ Res. 2018 03 16; 122(6):864-876. PMID: 29437835; PMCID: PMC5924425.
    Citations: 22     Fields:    Translation:Humans
  15. Opotowsky AR, Hess E, Maron BA, Brittain EL, Barón AE, Maddox TM, Alshawabkeh LI, Wertheim BM, Xu M, Assad TR, Rich JD, Choudhary G, Tedford RJ. Thermodilution vs Estimated Fick Cardiac Output Measurement in Clinical Practice: An Analysis of Mortality From the Veterans Affairs Clinical Assessment, Reporting, and Tracking (VA CART) Program and Vanderbilt University. JAMA Cardiol. 2017 10 01; 2(10):1090-1099. PMID: 28877293.
    Citations: 22     Fields:    Translation:Humans
  16. Rudolf JW, Dighe AS, Coley CM, Kamis IK, Wertheim BM, Wright DE, Lewandrowski KB, Baron JM. Analysis of Daily Laboratory Orders at a Large Urban Academic Center: A Multifaceted Approach to Changing Test Ordering Patterns. Am J Clin Pathol. 2017 Aug 01; 148(2):128-135. PMID: 28898984; PMCID: PMC6322419.
    Citations: 5     Fields:    Translation:Humans
  17. Wertheim BM, Aguirre AJ, Bhattacharyya RP, Chorba J, Jadhav AP, Kerry VB, Macklin EA, Motyckova G, Raju S, Lewandrowski K, Hunt DP, Wright DE. An Educational and Administrative Intervention to Promote Rational Laboratory Test Ordering on an Academic General Medicine Service. Am J Med. 2017 Jan; 130(1):47-53. PMID: 27619354; PMCID: PMC6598201.
    Citations: 7     Fields:    Translation:Humans
  18. Sokolowsky K, Newton M, Lucero C, Wertheim B, Freedman J, Cortazar F, Czochor J, Schelvis JP, Gindt YM. Spectroscopic and thermodynamic comparisons of Escherichia coli DNA photolyase and Vibrio cholerae cryptochrome 1. J Phys Chem B. 2010 May 27; 114(20):7121-30. PMID: 20438097.
    Citations: 5     Fields:    Translation:Cells
  19. Banagan BL, Wertheim BM, Roth MJ, Caslake LF. Microbial strengthening of loose sand. Lett Appl Microbiol. 2010 Aug; 51(2):138-42. PMID: 20557452.
    Citations: 1     Fields:    Translation:CellsPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.