Harvard Catalyst Profiles

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Esak Lee, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hassell BA, Goyal G, Lee E, Sontheimer-Phelps A, Levy O, Chen CS, Ingber DE. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Rep. 2018 Jun 19; 23(12):3698. PMID: 29925009.
    Citations:    Fields:    
  2. Bressler EM, Kim J, Shmueli RB, Mirando AC, Bazzazi H, Lee E, Popel AS, Pandey NB, Green JJ. Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells. J Biomed Mater Res A. 2018 06; 106(6):1753-1764. PMID: 29424479.
    Citations:    Fields:    
  3. Hassell BA, Goyal G, Lee E, Sontheimer-Phelps A, Levy O, Chen CS, Ingber DE. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Rep. 2017 Oct 10; 21(2):508-516. PMID: 29020635.
    Citations: 10     Fields:    Translation:HumansCells
  4. Choi D, Park E, Jung E, Seong YJ, Yoo J, Lee E, Hong M, Lee S, Ishida H, Burford J, Peti-Peterdi J, Adams RH, Srikanth S, Gwack Y, Chen CS, Vogel HJ, Koh CJ, Wong AK, Hong YK. Laminar flow downregulates Notch activity to promote lymphatic sprouting. J Clin Invest. 2017 Apr 03; 127(4):1225-1240. PMID: 28263185.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  5. Dore-Savard L, Lee E, Kakkad S, Popel AS, Bhujwalla ZM. The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts. Sci Rep. 2016 12 20; 6:39460. PMID: 27995973.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Lee E, Song HG, Chen CS. Biomimetic on-a-chip platforms for studying cancer metastasis. Curr Opin Chem Eng. 2016 Feb; 11:20-27. PMID: 27570735.
    Citations: 4     
  7. Fertig EJ, Lee E, Pandey NB, Popel AS. Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes. Sci Rep. 2015 Jul 15; 5:12133. PMID: 26173622.
    Citations: 8     Fields:    Translation:Humans
  8. Lee E, Pandey NB, Popel AS. Crosstalk between cancer cells and blood endothelial and lymphatic endothelial cells in tumour and organ microenvironment. Expert Rev Mol Med. 2015 Jan 30; 17:e3. PMID: 25634527.
    Citations: 15     Fields:    Translation:HumansCells
  9. Lee E, Lee SJ, Koskimaki JE, Han Z, Pandey NB, Popel AS. Inhibition of breast cancer growth and metastasis by a biomimetic peptide. Sci Rep. 2014 Nov 20; 4:7139. PMID: 25409905.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  10. Kim E, Lee E, Plummer C, Gil S, Popel AS, Pathak AP. Vasculature-specific MRI reveals differential anti-angiogenic effects of a biomimetic peptide in an orthotopic breast cancer model. Angiogenesis. 2015 Apr; 18(2):125-36. PMID: 25408417.
    Citations:    Fields:    Translation:HumansAnimalsCells
  11. Rosca EV, Penet MF, Mori N, Koskimaki JE, Lee E, Pandey NB, Bhujwalla ZM, Popel AS. A biomimetic collagen derived peptide exhibits anti-angiogenic activity in triple negative breast cancer. PLoS One. 2014; 9(11):e111901. PMID: 25384034.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  12. Chu LH, Lee E, Bader JS, Popel AS. Angiogenesis interactome and time course microarray data reveal the distinct activation patterns in endothelial cells. PLoS One. 2014; 9(10):e110871. PMID: 25329517.
    Citations: 5     Fields:    Translation:HumansCells
  13. Lee E, Fertig EJ, Jin K, Sukumar S, Pandey NB, Popel AS. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun. 2014 Sep 02; 5:4715. PMID: 25178650.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  14. Lee E, Pandey NB, Popel AS. Lymphatic endothelial cells support tumor growth in breast cancer. Sci Rep. 2014 Jul 28; 4:5853. PMID: 25068296.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  15. Lee E, Pandey NB, Popel AS. Pre-treatment of mice with tumor-conditioned media accelerates metastasis to lymph nodes and lungs: a new spontaneous breast cancer metastasis model. Clin Exp Metastasis. 2014 Jan; 31(1):67-79. PMID: 23963763.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  16. Lee E, Koskimaki JE, Pandey NB, Popel AS. Inhibition of lymphangiogenesis and angiogenesis in breast tumor xenografts and lymph nodes by a peptide derived from transmembrane protein 45A. Neoplasia. 2013 Feb; 15(2):112-24. PMID: 23441126.
    Citations: 22     Fields:    Translation:Humans
  17. Koskimaki JE, Lee E, Chen W, Rivera CG, Rosca EV, Pandey NB, Popel AS. Synergy between a collagen IV mimetic peptide and a somatotropin-domain derived peptide as angiogenesis and lymphangiogenesis inhibitors. Angiogenesis. 2013 Jan; 16(1):159-70. PMID: 23053781.
    Citations: 10     Fields:    Translation:HumansCells
  18. Koskimaki JE, Rosca EV, Rivera CG, Lee E, Chen W, Pandey NB, Popel AS. Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth. Transl Oncol. 2012 Apr; 5(2):92-7. PMID: 22496925.
    Citations: 7     
  19. Lee E, Rosca EV, Pandey NB, Popel AS. Small peptides derived from somatotropin domain-containing proteins inhibit blood and lymphatic endothelial cell proliferation, migration, adhesion and tube formation. Int J Biochem Cell Biol. 2011 Dec; 43(12):1812-21. PMID: 21920451.
    Citations: 16     Fields:    Translation:HumansCells
  20. Lee E, Kim YS, Bae SM, Kim SK, Jin S, Chung SW, Lee M, Moon HT, Jeon OC, Park RW, Kim IS, Byun Y, Kim SY. Polyproline-type helical-structured low-molecular weight heparin (LMWH)-taurocholate conjugate as a new angiogenesis inhibitor. Int J Cancer. 2009 Jun 15; 124(12):2755-65. PMID: 19243020.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.