Harvard Catalyst Profiles

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Sylvia E.J. Fischer, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Braun M, Shoshani S, Teixeira J, Mellul Shtern A, Miller M, Granot Z, Fischer SEJ, Garcia SMDA, Tabach Y. Asymmetric inheritance of RNA toxicity in C. elegans expressing CTG repeats. iScience. 2022 May 20; 25(5):104246. PMID: 35494247; PMCID: PMC9051633.
  2. Fischer SEJ, Ruvkun G. Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):5987-5996. PMID: 32123111.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  3. Newman MA, Ji F, Fischer SEJ, Anselmo A, Sadreyev RI, Ruvkun G. The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes. Genes Dev. 2018 05 01; 32(9-10):670-681. PMID: 29739806; PMCID: PMC6004069.
    Citations: 11     Fields:    Translation:AnimalsCells
  4. Fischer SEJ. RNA Interference and MicroRNA-Mediated Silencing. Curr Protoc Mol Biol. 2015 Oct 01; 112:26.1.1-26.1.5. PMID: 26423588.
    Citations: 14     Fields:    
  5. Billi AC, Fischer SE, Kim JK. Endogenous RNAi pathways in C. elegans. WormBook. 2014 May 07; 1-49. PMID: 24816713.
    Citations: 55     Fields:    Translation:Animals
  6. Fischer SE, Pan Q, Breen PC, Qi Y, Shi Z, Zhang C, Ruvkun G. Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans. Genes Dev. 2013 Dec 15; 27(24):2678-95. PMID: 24352423.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  7. Zhang C, Montgomery TA, Fischer SE, Garcia SM, Riedel CG, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Curr Biol. 2012 May 22; 22(10):881-90. PMID: 22542102.
    Citations: 29     Fields:    Translation:AnimalsCells
  8. Montgomery TA, Rim YS, Zhang C, Dowen RH, Phillips CM, Fischer SE, Ruvkun G. PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1. PLoS Genet. 2012; 8(4):e1002616. PMID: 22536158.
    Citations: 73     Fields:    Translation:AnimalsCells
  9. Fischer SE, Montgomery TA, Zhang C, Fahlgren N, Breen PC, Hwang A, Sullivan CM, Carrington JC, Ruvkun G. The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications. PLoS Genet. 2011 Nov; 7(11):e1002369. PMID: 22102828.
    Citations: 42     Fields:    Translation:AnimalsCells
  10. Zhang C, Montgomery TA, Gabel HW, Fischer SE, Phillips CM, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G. mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1201-8. PMID: 21245313.
    Citations: 75     Fields:    Translation:AnimalsCells
  11. Fischer SE. Small RNA-mediated gene silencing pathways in C. elegans. Int J Biochem Cell Biol. 2010 Aug; 42(8):1306-15. PMID: 20227516.
    Citations: 22     Fields:    Translation:AnimalsCells
  12. Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT. RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans. PLoS One. 2009 Dec 14; 4(12):e8210. PMID: 20011587.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  13. Fischer SE, Butler MD, Pan Q, Ruvkun G. Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7. Nature. 2008 Sep 25; 455(7212):491-6. PMID: 18784652.
    Citations: 54     Fields:    Translation:AnimalsCells
  14. Vastenhouw NL, Fischer SE, Robert VJ, Thijssen KL, Fraser AG, Kamath RS, Ahringer J, Plasterk RH. A genome-wide screen identifies 27 genes involved in transposon silencing in C. elegans. Curr Biol. 2003 Aug 05; 13(15):1311-6. PMID: 12906791.
    Citations: 71     Fields:    Translation:AnimalsCells
  15. Fischer SE, Wienholds E, Plasterk RH. Continuous exchange of sequence information between dispersed Tc1 transposons in the Caenorhabditis elegans genome. Genetics. 2003 May; 164(1):127-34. PMID: 12750326.
    Citations: 18     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.