Harvard Catalyst Profiles

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Daniel James Firl, M.D.

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Biography
Cleveland Clinic Lerner College of Medicine, Cleveland, OHMD05/2018
Duke University, Durham, NCSurgery
2015 - 2016
HHMI Medical Research Fellow
2021 - 2022
AST/Mallinckrodt Translational Science Fellowship

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Firl DJ, Markmann JF. Reply to "Letter to the editor in response to: Measuring success in pig to non-human-primate renal xenotransplantation: Systematic review and comparative outcomes analysis of 1051 life-sustaining NHP renal allo- and xeno-transplants". Am J Transplant. 2022 09; 22(9):2279-2280. PMID: 35278274.
    Citations:    Fields:    
  2. Firl DJ, Markmann JF. Measuring success in pig to non-human-primate renal xenotransplantation: Systematic review and comparative outcomes analysis of 1051 life-sustaining NHP renal allo- and xeno-transplants. Am J Transplant. 2022 06; 22(6):1527-1536. PMID: 35143091.
    Citations: 2     Fields:    Translation:HumansAnimals
  3. Sasaki K, Nair A, Firl DJ, McVey JC, El-Gazzaz G, Diago Uso T, Fujiki M, Aucejo FN, Quintini C, Kwon CD, Hashimoto K, Miller CM, Eghtesad B. Should We Be Utilizing More Liver Grafts From Pediatric Donation After Circulatory Death Donors? A National Analysis of the SRTR from 2002 to 2017. Transplantation. 2021 09 01; 105(9):1998-2006. PMID: 32947583.
    Citations: 1     Fields:    Translation:Humans
  4. Sasaki K, Nair A, Firl DJ, McVey JC, Moro A, Diago Uso T, Fujiki M, Aucejo FN, Quintini C, Kwon CD, Eghtesad B, Miller CM, Hashimoto K. Conditional probability of graft survival in liver transplantation using donation after circulatory death grafts - a retrospective study. Transpl Int. 2021 Aug; 34(8):1433-1443. PMID: 33599045.
    Citations: 1     Fields:    Translation:Humans
  5. McVey JC, Sasaki K, Firl DJ. Risk assessment criteria in liver transplantation for hepatocellular carcinoma: proposal to improve transplant oncology. Hepat Oncol. 2020 Jul 24; 7(3):HEP26. PMID: 32774836; PMCID: PMC7399580.
    Citations:    
  6. McVey JC, Sasaki K, Firl DJ, Fujiki M, Diago-Uso T, Quintini C, Eghtesad B, Miller CC, Hashimoto K, Aucejo FN. Prognostication of inflammatory cells in liver transplantation: Is the waitlist neutrophil-to-lymphocyte ratio really predictive of tumor biology? Clin Transplant. 2019 12; 33(12):e13743. PMID: 31655000.
    Citations: 2     Fields:    Translation:HumansCells
  7. Sasaki K, McVey JC, Firl DJ, Andreatos N, Moro A, Coromina Hernandez L, Matsushima H, Teresa DU, Fujiki M, Aucejo FN, Quintini C, Kwon CD, Eghtesad B, Miller CM, Hashimoto K. Sufficient hepatic artery flow compensates for poor portal vein flow after liver transplantation in patients with portal vein thrombosis. Clin Transplant. 2019 11; 33(11):e13723. PMID: 31583762.
    Citations:    Fields:    Translation:Humans
  8. Firl DJ, Sasaki K, Agopian VG, Gorgen A, Kimura S, Dumronggittigule W, McVey JC, Iesari S, Mennini G, Vitale A, Finkenstedt A, Onali S, Hoppe-Lotichius M, Vennarecci G, Manzia TM, Nicolini D, Avolio AW, Agnes S, Vivarelli M, Tisone G, Ettorre GM, Otto G, Tsochatzis E, Rossi M, Viveiros A, Cillo U, Markmann JF, Ikegami T, Kaido T, Lai Q, Sapisochin G, Lerut J, Aucejo FN. Charting the Path Forward for Risk Prediction in Liver Transplant for Hepatocellular Carcinoma: International Validation of HALTHCC Among 4,089 Patients. Hepatology. 2020 02; 71(2):569-582. PMID: 31243778.
    Citations: 15     Fields:    Translation:Humans
  9. Firl DJ, Sasaki K, McVey J, Hupertz V, Radhakrishnan K, Fujiki M, Eghtesad B, Miller CM, Quintini C, Hashimoto K. Improved Survival Following Living Donor Liver Transplantation for Pediatric Acute Liver Failure: Analysis of 20 Years of US National Registry Data. Liver Transpl. 2019 08; 25(8):1241-1250. PMID: 31119826.
    Citations: 6     Fields:    Translation:Humans
  10. Sasaki K, Firl DJ, McVey JC, Schold JD, Iuppa G, Diago Uso T, Fujiki M, Aucejo FN, Quintini C, Eghetsad B, Miller CM, Hashimoto K. Elevated Risk of Split-Liver grafts in adult liver Transplantation: Statistical Artifact or Nature of the Beast? Liver Transpl. 2019 05; 25(5):741-751. PMID: 30615254.
    Citations: 7     Fields:    Translation:Humans
  11. Kusakabe J, Firl DJ, Sasaki K. Toward the universal scoring system in treatment for patients with hepatocellular carcinoma. J Hepatol. 2019 03; 70(3):568-570. PMID: 30554931.
    Citations:    Fields:    Translation:Humans
  12. McVey JC, Sasaki K, Margonis GA, Nowacki AS, Firl DJ, He J, Berber E, Wolfgang C, Miller CC, Weiss M, Aucejo FN. The impact of resection margin on overall survival for patients with colon cancer liver metastasis varied according to the primary cancer location. HPB (Oxford). 2019 06; 21(6):702-710. PMID: 30501989.
    Citations: 3     Fields:    Translation:Humans
  13. Firl DJ, Kimura S, McVey J, Hashimoto K, Yeh H, Miller CM, Markmann JF, Sasaki K, Aucejo FN. Reframing the approach to patients with hepatocellular carcinoma: Longitudinal assessment with hazard associated with liver transplantation for HCC (HALTHCC) improves ablate and wait strategy. Hepatology. 2018 10; 68(4):1448-1458. PMID: 29604231.
    Citations: 6     Fields:    Translation:Humans
  14. Jones JC, Alomar S, McGovern RA, Firl D, Fitzgerald Z, Gale J, Gonzalez-Martinez JA. Techniques for placement of stereotactic electroencephalographic depth electrodes: Comparison of implantation and tracking accuracies in a cadaveric human study. Epilepsia. 2018 09; 59(9):1667-1675. PMID: 30142255.
    Citations: 2     Fields:    Translation:Humans
  15. Firl DJ, Degn SE, Padera T, Carroll MC. Capturing change in clonal composition amongst single mouse germinal centers. Elife. 2018 08 01; 7. PMID: 30066671.
    Citations: 8     Fields:    Translation:AnimalsCells
  16. Firl DJ, Sasaki K, Aucejo FN. Predicting Outcomes of Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma. Gastroenterology. 2018 05; 154(6):1856-1857. PMID: 29621517.
    Citations:    Fields:    Translation:Humans
  17. Degn SE, van der Poel CE, Firl DJ, Ayoglu B, Al Qureshah FA, Bajic G, Mesin L, Reynaud CA, Weill JC, Utz PJ, Victora GD, Carroll MC. Clonal Evolution of Autoreactive Germinal Centers. Cell. 2017 Aug 24; 170(5):913-926.e19. PMID: 28841417.
    Citations: 48     Fields:    Translation:AnimalsCells
  18. Elshamy M, Presser N, Hammad AY, Firl DJ, Coppa C, Fung J, Aucejo FN. Liver transplantation in patients with incidental hepatocellular carcinoma/cholangiocarcinoma and intrahepatic cholangiocarcinoma: a single-center experience. Hepatobiliary Pancreat Dis Int. 2017 Jun; 16(3):264-270. PMID: 28603094.
    Citations: 6     Fields:    Translation:Humans
  19. Sasaki K, Firl DJ, Hashimoto K, Fujiki M, Diago-Uso T, Quintini C, Eghtesad B, Fung JJ, Aucejo FN, Miller CM. Development and validation of the HALT-HCC score to predict mortality in liver transplant recipients with hepatocellular carcinoma: a retrospective cohort analysis. Lancet Gastroenterol Hepatol. 2017 08; 2(8):595-603. PMID: 28546007.
    Citations: 21     Fields:    Translation:Humans
  20. Firl DJ, Benichou G, Kim JI, Yeh H. A Paradigm Shift on the Question of B Cells in Transplantation? Recent Insights on Regulating the Alloresponse. Front Immunol. 2017; 8:80. PMID: 28210263.
    Citations: 5     Fields:    
  21. Firl DJ, Hashimoto K, O'Rourke C, Diago-Uso T, Fujiki M, Aucejo FN, Quintini C, Kelly DM, Miller CM, Fung JJ, Eghtesad B. Role of donor hemodynamic trajectory in determining graft survival in liver transplantation from donation after circulatory death donors. Liver Transpl. 2016 11; 22(11):1469-1481. PMID: 27600806.
    Citations: 2     Fields:    Translation:Humans
  22. Firl DJ, Hashimoto K, O'Rourke C, Diago-Uso T, Fujiki M, Aucejo FN, Quintini C, Kelly DM, Miller CM, Fung JJ, Eghtesad B. Impact of donor age in liver transplantation from donation after circulatory death donors: A decade of experience at Cleveland Clinic. Liver Transpl. 2015 Dec; 21(12):1494-503. PMID: 26334196.
    Citations: 6     Fields:    Translation:Humans
  23. Jantzie LL, Getsy PM, Denson JL, Firl DJ, Maxwell JR, Rogers DA, Wilson CG, Robinson S. Prenatal Hypoxia-Ischemia Induces Abnormalities in CA3 Microstructure, Potassium Chloride Co-Transporter 2 Expression and Inhibitory Tone. Front Cell Neurosci. 2015; 9:347. PMID: 26388734; PMCID: PMC4558523.
    Citations: 17     
  24. Jantzie LL, Corbett CJ, Berglass J, Firl DJ, Flores J, Mannix R, Robinson S. Complex pattern of interaction between in utero hypoxia-ischemia and intra-amniotic inflammation disrupts brain development and motor function. J Neuroinflammation. 2014 Aug 01; 11:131. PMID: 25082427.
    Citations: 29     Fields:    Translation:AnimalsCells
  25. Jantzie LL, Getsy PM, Firl DJ, Wilson CG, Miller RH, Robinson S. Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury. Mol Cell Neurosci. 2014 Jul; 61:152-62. PMID: 24983520.
    Citations: 28     Fields:    Translation:Animals
  26. Jantzie LL, Corbett CJ, Firl DJ, Robinson S. Postnatal Erythropoietin Mitigates Impaired Cerebral Cortical Development Following Subplate Loss from Prenatal Hypoxia-Ischemia. Cereb Cortex. 2015 Sep; 25(9):2683-95. PMID: 24722771.
    Citations: 36     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.