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Shuhan He, M.D.

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Harvard Affiliated Emergency Medicine Residency, Boston, MA06/2019Emergency Medicine
Keck School of Medicine, Los Angeles, CAMD06/2015Medicine
University of Wisconsin-Madison, Madison, WIBS2009Biological Sciences
The Boston Business Journal 40 Under 40 2021
Modern HealthCare Top 25 Emerging Leaders
EMRA’s 25 Under 45 Influencers in Emergency Medicine
Language for Equity--Doctorlingo.com
Richard C Wuerz, MD Scholarship for Emergency Medicine Research.
2015 Irving I. Lasky M.D., Memorial Award
Market Traction Award. BriskRabbit Physiologic Portable Temperature Monitoring Device
Dean’s Research Scholarship


Available: 01/10/22, Expires: 02/01/23

There has been little standardization among visual analogue scales used to measure pain severity and quality of care in medicine. We propose that we can capture health outcome data using a universal and open-access Emoji-based visual analogue scale(EbVAS) in place of current Visual analogue scales(VAS), which are trademarked and not digitally native. Subjects in the Intensive Care Unit (ICU) of Mass General Hospital(MGH) will be asked to score their pain intensity using the EbVAS, compare their EbVAS to a traditional the Numerical Rating Scale (NRS), and use a novel EbVAS to describe the quality and nature of their symptoms. A scientifically validated universal and open access EbVAS has impacts for tools like telemedicine and digital health applications, healthcare cost controls through shifts from fee for service to accountable care compensation models, and improvements in healthcare communication, language and accessibility. Introduction: The worldwide accepted definition of pain by the International Association for the Study of Pain (IASP) is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage (Merskey, 1994). For effective pain treatment, pain needs to be recognized and described accurately. The pain literature contains many pain intensity rating techniques, but patient's self-report is the most precise and reliable method to measure the existence and intensity of current pain. There are various types of self-report visual analog pain scales. For example, Wong-Baker FACES Pain Rating Scale and Colored Analogue Scale (Stinson, Kavanagh, Yamada, & Stevens, 2006) are used to measure pain in children while somewhat nonphysical rating scales such as Verbal Rating Scale (VRS), and Numeric Rating Scale (NRS), are used mostly for adults. Other visual rating scales currently in use include Smileyometer (Read & Macfarlane, 2002), AffectButton (Broekens, 2014), EmoCards (Desmet, Overbeeke, & Tax, 2001), Biberoglu and Behrman Scale (Biberoglu & Behrman, 1981). There has been little standardization among these scales. We propose that Emoji, representing a universal language common to people from all backgrounds and age groups, will make a practical visual analog scale that is free-to-use without trademarks. Moreover, most visual analog scales were designed for paper whereas Emoji are digitally native and can make up-to-date versions of visual analog scales (Lai et al 2021). Aim 1. To determine the extent to which patients in the Intensive Care Unit can accurately describe their pain using a visual analogue scale created from standard Emoji Sets from Unicode V12.0. Aim 2. To determine the extent to which patients in the Intensive Care Unit can accurately describe the nature of their symptoms using a visual analogue scale from standard Emoji Sets from Unicode V12.0. Aim 3. To determine the extent to which there is an agreement between patient's severity description of their pain using the Numerical Rating Scale and patient's description of their pain using a visual analogue scale created from standard Emoji Sets from Unicode V12.0. Role for Student: manuscript writing, data analysis, data collection Prior Skills: none Reference Reading: https://jamanetwork.com/journals/jama/article-abstract/2783847

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. (Shuhan He) Mar 1, 2020
    Foundation for Opioid Response Efforts (FORE)
    GetWaivered Digital

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Renne A, He S, Lee J. An Emoji-Based Visual Analog Scale Compared With a Numeric Rating Scale for Pain Assessment-Reply. JAMA. 2022 11 15; 328(19):1980-1981. PMID: 36378209.
    Citations:    Fields:    
  2. Marzouk S, He S, Lee J. Emoji Education: How Students Can Help Increase Health Awareness by Making Emojis. JMIR Med Educ. 2022 Nov 11; 8(4):e39059. PMID: 36367758; PMCID: PMC9700240.
  3. He S, Shyamsundar S, Chong P, Kannikal J, Calvano J, Balapal N, Kallenberg N, Balaji A, Ankem A, Martin A. Analyzing opioid-use disorder websites in the United States: An optimized website usability study. Digit Health. 2022 Jan-Dec; 8:20552076221121529. PMID: 36225987; PMCID: PMC9549183.
  4. He S, Renne A, Argandykov D, Convissar D, Lee J. Comparison of an Emoji-Based Visual Analog Scale With a Numeric Rating Scale for Pain Assessment. JAMA. 2022 07 12; 328(2):208-209. PMID: 35819433; PMCID: PMC9277495.
    Citations:    Fields:    Translation:Humans
  5. Seethapathy H, Beach J, Gillcrist M, Conway PT, Teakell J, Lee J, Vlasschaert C, He S, Lerma E. The Case for a Kidney Emoji. Am J Kidney Dis. 2022 08; 80(2):155-157. PMID: 35513182.
    Citations:    Fields:    Translation:Humans
  6. He S, Marzouk S, Balk A, Boyle T, Lee J. The telehealth advantage: Supporting humanitarian disasters with remote solutions. Am J Disaster Med. 2022; 17(2):95-99. PMID: 36494880.
    Citations:    Fields:    
  7. Balk A, Lee J, Renne C, He S. The liver emoji. Hepatology. 2022 05; 75(5):1073-1074. PMID: 34860429.
    Citations:    Fields:    
  8. Martin A, Raber JP, Shayer D, Lai D, Goodcoff A, Kannikal J, Raja AS, He S. Get waivered remote: Nationwide, remote DEA-x waiver course in response to COVID-19. Digit Health. 2021 Jan-Dec; 7:20552076211048985. PMID: 34691756; PMCID: PMC8529309.
    Citations: 1     
  9. Jaffe TA, Wang D, Loveless B, Lai D, Loesche M, White B, Raja AS, He S. A Scoping Review of Emergency Department Discharge Risk Stratification. West J Emerg Med. 2021 Sep 23; 22(6):1218-1226. PMID: 34787544.
    Citations:    Fields:    Translation:Humans
  10. Lai D, Lee J8, He S. Emoji for the Medical Community-Challenges and Opportunities. JAMA. 2021 09 07; 326(9):795-796. PMID: 34547099.
    Citations: 2     Fields:    Translation:Humans
  11. Lai D, Wang D, McGillivray M, Baajour S, Raja AS, He S. Assessing the quality of randomization methods in randomized control trials. Healthc (Amst). 2021 Dec; 9(4):100570. PMID: 34343852.
    Citations:    Fields:    Translation:HumansCells
  12. He S, Ivkovic V, Friedstat J, Lee J. Physician and first responder collaborations to ease personal protective equipment shortages. Am J Emerg Med. 2022 05; 55:213. PMID: 34229941; PMCID: PMC8240462.
    Citations:    Fields:    Translation:Humans
  13. He S, Bala R, Anupindi R, Ranney ML. Effective supply chain surveillance for PPE. Lancet. 2021 05 08; 397(10286):1706-1707. PMID: 33965082; PMCID: PMC8102039.
    Citations: 1     Fields:    Translation:PHPublic Health
  14. Fundingsland E, Fike J, Calvano J, Raja A, Lai D, Silacci S, Haas M, Chan T, He S. Website usability analysis of United States emergency medicine residencies. AEM Educ Train. 2021 Jul; 5(3):e10604. PMID: 34124531; PMCID: PMC8171769.
    Citations: 2     
  15. Calvano JD, Fundingsland EL, Lai D, Silacci S, Raja AS, He S. Applying Website Rankings to Digital Health Centers in the United States to Assess Public Engagement: Website Usability Study. JMIR Hum Factors. 2021 Mar 29; 8(1):e20721. PMID: 33779564.
    Citations: 3     
  16. He S, Lai D, Lee J. The medical right to repair: the right to save lives. Lancet. 2021 04 03; 397(10281):1260-1261. PMID: 33773116; PMCID: PMC7990498.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  17. Bala R, Lee C, Pallant B, Srinivasan M, Lurie D, Jacob R, Bhagchandani N, Ranney M, He S. Algorithmic matching of personal protective equipment donations with healthcare facilities during the COVID-19 pandemic. NPJ Digit Med. 2021 Jan 29; 4(1):13. PMID: 33514805; PMCID: PMC7846564.
    Citations: 1     
  18. Jordan J, Sternberg K, Haas MRC, He S, Yarris LM, Chan TM, Deiorio NM. Reimagining Residency Selection: Part 3-A Practical Guide to Ranking Applicants in the Post-COVID-19 Era. J Grad Med Educ. 2020 Dec; 12(6):666-670. PMID: 33391587.
    Citations: 3     Fields:    Translation:Humans
  19. Lai L, Wittbold KA, Dadabhoy FZ, Sato R, Landman AB, Schwamm LH, He S, Patel R, Wei N, Zuccotti G, Lennes IT, Medina D, Sequist TD, Bomba G, Keschner YG, Zhang HM. Digital triage: Novel strategies for population health management in response to the COVID-19 pandemic. Healthc (Amst). 2020 Dec; 8(4):100493. PMID: 33129176.
    Citations: 18     Fields:    Translation:HumansPHPublic Health
  20. Lai D, Wang D, Calvano J, Raja AS, He S. Addressing immediate public coronavirus (COVID-19) concerns through social media: Utilizing Reddit's AMA as a framework for Public Engagement with Science. PLoS One. 2020; 15(10):e0240326. PMID: 33021985.
    Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
  21. Haas MRC, He S, Sternberg K, Jordan J, Deiorio NM, Chan TM, Yarris LM. Reimagining Residency Selection: Part 1-A Practical Guide to Recruitment in the Post-COVID-19 Era. J Grad Med Educ. 2020 Oct; 12(5):539-544. PMID: 33149819.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  22. Sternberg K, Jordan J, Haas MRC, He S, Deiorio NM, Yarris LM, Chan TM. Reimagining Residency Selection: Part 2-A Practical Guide to Interviewing in the Post-COVID-19 Era. J Grad Med Educ. 2020 Oct; 12(5):545-549. PMID: 33149820.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  23. Lai L, Sato R, He S, Ouchi K, Leiter R, deLima Thomas J, Lawton A, Landman AB, Mark Zhang H. Usage Patterns of a Web-Based Palliative Care Content Platform (PalliCOVID) During the COVID-19 Pandemic. J Pain Symptom Manage. 2020 10; 60(4):e20-e27. PMID: 32730951.
    Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
  24. He S, Ojo A, Beckman AL, Gondi S, Gondi S, Betz M, Faust JS, Choo E, Kass D, Raja AS. The Story of #GetMePPE and GetUsPPE.org to Mobilize Health Care Response to COVID-19 : Rapidly Deploying Digital Tools for Better Health Care. J Med Internet Res. 2020 07 20; 22(7):e20469. PMID: 32530813.
    Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
  25. He S, Lai D, Mott S, Little A, Grock A, Haas MRC, Chan TM. Remote e-Work and Distance Learning for Academic Medicine: Best Practices and Opportunities for the Future. J Grad Med Educ. 2020 Jun; 12(3):256-263. PMID: 32595840.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  26. Gondi S, Beckman AL, Deveau N, Raja AS, Ranney ML, Popkin R, He S. Personal protective equipment needs in the USA during the COVID-19 pandemic. Lancet. 2020 05 23; 395(10237):e90-e91. PMID: 32416784; PMCID: PMC7255297.
    Citations: 25     Fields:    Translation:HumansCellsPHPublic Health
  27. Russin JJ, Montagne A, D'Amore F, He S, Shiroishi MS, Rennert RC, Depetris J, Zlokovic BV, Mack WJ. Permeability imaging as a predictor of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2018 06; 38(6):973-979. PMID: 29611451; PMCID: PMC5998996.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  28. Patel A, Moalem A, Cheng H, Babadjouni RM, Patel K, Hodis DM, Chandegara D, Cen S, He S, Liu Q, Mack WJ. Chronic cerebral hypoperfusion induced by bilateral carotid artery stenosis causes selective recognition impairment in adult mice. Neurol Res. 2017 Oct; 39(10):910-917. PMID: 28828966; PMCID: PMC5591078.
    Citations: 10     Fields:    Translation:AnimalsCells
  29. Ramirez L, Kim-Tenser MA, Sanossian N, Cen S, Wen G, He S, Mack WJ, Towfighi A. Trends in Transient Ischemic Attack Hospitalizations in the United States. J Am Heart Assoc. 2016 Sep 24; 5(9). PMID: 27664805.
    Citations: 4     Fields:    
  30. Ramirez L, Kim-Tenser MA, Sanossian N, Cen S, Wen G, He S, Mack WJ, Towfighi A. Trends in Acute Ischemic Stroke Hospitalizations in the United States. J Am Heart Assoc. 2016 05 11; 5(5). PMID: 27169548; PMCID: PMC4889194.
    Citations: 56     Fields:    Translation:Humans
  31. Liu Q, Babadjouni R, Radwanski R, Cheng H, Patel A, Hodis DM, He S, Baumbacher P, Russin JJ, Morgan TE, Sioutas C, Finch CE, Mack WJ. Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model. PLoS One. 2016; 11(4):e0153376. PMID: 27071057.
    Citations: 10     Fields:    Translation:Animals
  32. Wen T, Attenello FJ, He S, Cen Y, Kim-Tenser MA, Sanossian N, Amar AP, Mack WJ. Racial and socioeconomic disparities in incidence of hospital-acquired complications following cerebrovascular procedures. Neurosurgery. 2014 Jul; 75(1):43-50. PMID: 24662507.
    Citations: 12     Fields:    Translation:Humans
  33. Hanks N, Wen G, He S, Song S, Saver JL, Cen S, Kim-Tenser M, Mack W, Sanossian N. Expansion of U.S. emergency medical service routing for stroke care: 2000-2010. West J Emerg Med. 2014 Jul; 15(4):499-503. PMID: 25035758.
    Citations: 6     Fields:    Translation:Humans
  34. Wen T, He S, Attenello F, Cen SY, Kim-Tenser M, Adamczyk P, Amar AP, Sanossian N, Mack WJ. The impact of patient age and comorbidities on the occurrence of "never events" in cerebrovascular surgery: an analysis of the Nationwide Inpatient Sample. J Neurosurg. 2014 Sep; 121(3):580-6. PMID: 24972123.
    Citations: 7     Fields:    Translation:Humans
  35. Liu Q, He S, Groysman L, Shaked D, Russin J, Scotton TC, Cen S, Mack WJ. White matter injury due to experimental chronic cerebral hypoperfusion is associated with C5 deposition. PLoS One. 2013; 8(12):e84802. PMID: 24386419.
    Citations: 14     Fields:    Translation:Animals
  36. Chang X, Shi L, Gao F, Russin J, Zeng L, He S, Chen TC, Giannotta SL, Weisenberger DJ, Zada G, Wang K, Mack WJ. Genomic and transcriptome analysis revealing an oncogenic functional module in meningiomas. Neurosurg Focus. 2013 Dec; 35(6):E3. PMID: 24289128.
    Citations: 15     Fields:    Translation:HumansCells
  37. He S, Pham MH, Pease M, Zada G, Giannotta SL, Wang K, Mack WJ. A review of epigenetic and gene expression alterations associated with intracranial meningiomas. Neurosurg Focus. 2013 Dec; 35(6):E5. PMID: 24289130.
    Citations: 24     Fields:    Translation:Humans
  38. He S, Russin JJ, Adamczyk P, Giannotta SL, Amar AP, Mack WJ. A persistent primitive hypoglossal artery arising from the external carotid artery associated with subarachnoid hemorrhage. World Neurosurg. 2014 Jul-Aug; 82(1-2):239.e1-3. PMID: 23851212.
    Citations: 6     Fields:    Translation:Humans
  39. Attenello FJ, Adamczyk P, Wen G, He S, Zhang K, Russin JJ, Sanossian N, Amar AP, Mack WJ. Racial and socioeconomic disparities in access to mechanical revascularization procedures for acute ischemic stroke. J Stroke Cerebrovasc Dis. 2014 Feb; 23(2):327-34. PMID: 23680690; PMCID: PMC4467551.
    Citations: 13     Fields:    Translation:Humans
  40. Belur PK, Chang JJ, He S, Emanuel BA, Mack WJ. Emerging experimental therapies for intracerebral hemorrhage: targeting mechanisms of secondary brain injury. Neurosurg Focus. 2013 May; 34(5):E9. PMID: 23634928.
    Citations: 27     Fields:    Translation:Humans
  41. Adamczyk P, He S, Amar AP, Mack WJ. Medical Management of Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage: A Review of Current and Emerging Therapeutic Interventions. Neurol Res Int. 2013; 2013:462491. PMID: 23691312.
    Citations: 12     
  42. Mehta V, Russin J, Spirtos A, He S, Adamczyk P, Amar AP, Mack WJ. Matrix Metalloproteinases in Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage. Neurol Res Int. 2013; 2013:943761. PMID: 23691315.
    Citations: 2     
  43. He S, Mack WJ. Considering radiation exposure during diagnostic and therapeutic procedures for arteriovenous malformations in the setting of pregnancy. World Neurosurg. 2014 Jan; 81(1):22-4. PMID: 23416771.
    Citations: 1     Fields:    Translation:Humans
  44. Gao F, Shi L, Russin J, Zeng L, Chang X, He S, Chen TC, Giannotta SL, Weisenberger DJ, Zada G, Mack WJ, Wang K. DNA methylation in the malignant transformation of meningiomas. PLoS One. 2013; 8(1):e54114. PMID: 23349797.
    Citations: 31     Fields:    Translation:HumansCells
  45. He S, Mack WJ. Health-related quality of life after aneurysmal subarachnoid hemorrhage: interplay between physical, cognitive, and emotional factors. World Neurosurg. 2014 Jan; 81(1):37-9. PMID: 23333474.
    Citations: 1     Fields:    Translation:Humans
  46. Adamczyk P, Attenello F, Wen G, He S, Russin J, Sanossian N, Amar AP, Mack WJ. Mechanical thrombectomy in acute stroke: utilization variances and impact of procedural volume on inpatient mortality. J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):1263-9. PMID: 23017430.
    Citations: 14     Fields:    Translation:Humans
  47. Pham MH, Attenello FJ, Lucas J, He S, Stapleton CJ, Hsieh PC. Conservative management of ossification of the posterior longitudinal ligament. A review. Neurosurg Focus. 2011 Mar; 30(3):E2. PMID: 21434818.
    Citations: 13     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.