Harvard Catalyst Profiles

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Julian Bryan Iorgulescu, M.D.


Department of Pathology, Brigham and Women's Hospital
Department of Medical Oncology, Dana-Farber Cancer Institute
Computational Neuroscience Outcomes Center, Department of Neurosurgery
Harvard Medical School

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Iorgulescu JB, Sun C, Neff C, Cioffi G, Gutierrez C, Kruchko C, Ruhl J, Waite KA, Negoita S, Hofferkamp J, Tihan T, McLendon R, Brat DJ, Ostrom QT, Barnholtz-Sloan JS. Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States. Neuro Oncol. 2022 11 02; 24(11):1989-2000. PMID: 35460555; PMCID: PMC9629432.
    Citations:    Fields:    
  2. Liu S, Iorgulescu JB, Li S, Borji M, Barrera-Lopez IA, Shanmugam V, Lyu H, Morriss JW, Garcia ZN, Murray E, Reardon DA, Yoon CH, Braun DA, Livak KJ, Wu CJ, Chen F. Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response. Immunity. 2022 10 11; 55(10):1940-1952.e5. PMID: 36223726.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Papke DJ, Lindeman NI, Schrag D, Iorgulescu JB. Underutilization of Guideline-Recommended Mismatch Repair/Microsatellite Instability Biomarker Testing in Advanced Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2022 09 02; 31(9):1746-1751. PMID: 35767976; PMCID: PMC9444979.
    Citations:    Fields:    
  4. Ostrom QT, Shoaf ML, Cioffi G, Waite K, Kruchko C, Wen PY, Brat D, Barnholtz-Sloan JS, Iorgulescu JB. National-level overall survival patterns for molecularly-defined diffuse glioma types in the United States. Neuro Oncol. 2022 Aug 22. PMID: 35994777.
    Citations: 1     Fields:    
  5. Backlund CM, Holden RL, Moynihan KD, Garafola D, Farquhar C, Mehta NK, Maiorino L, Pham S, Iorgulescu JB, Reardon DA, Wu CJ, Pentelute BL, Irvine DJ. Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2204078119. PMID: 35914154; PMCID: PMC9371699.
    Citations: 2     Fields:    Translation:AnimalsCells
  6. Lamba N, Ott PA, Iorgulescu JB. Use of First-Line Immune Checkpoint Inhibitors and Association With Overall Survival Among Patients With Metastatic Melanoma in the Anti-PD-1 Era. JAMA Netw Open. 2022 08 01; 5(8):e2225459. PMID: 36006646; PMCID: PMC9412220.
    Citations:    Fields:    Translation:Humans
  7. Lee PC, Klaeger S, Le PM, Korthauer K, Cheng J, Ananthapadmanabhan V, Frost TC, Stevens JD, Wong AY, Iorgulescu JB, Tarren AY, Chea VA, Carulli IP, Lemvigh CK, Pedersen CB, Gartin AK, Sarkizova S, Wright KT, Li LW, Nomburg J, Li S, Huang T, Liu X, Pomerance L, Doherty LM, Apffel AM, Wallace LJ, Rachimi S, Felt KD, Wolff JO, Witten E, Zhang W, Neuberg D, Lane WJ, Zhang G, Olsen LR, Thakuria M, Rodig SJ, Clauser KR, Starrett GJ, Doench JG, Buhrlage SJ, Carr SA, DeCaprio JA, Wu CJ, Keskin DB. Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma. J Clin Invest. 2022 07 01; 132(13). PMID: 35775490; PMCID: PMC9246387.
    Citations:    Fields:    Translation:HumansCells
  8. Lim-Fat MJ, Youssef GC, Touat M, Iorgulescu JB, Whorral S, Allen M, Rahman R, Chukwueke U, McFaline-Figueroa JR, Nayak L, Lee EQ, Batchelor TT, Arnaout O, Peruzzi PP, Chiocca EA, Reardon DA, Meredith D, Santagata S, Beroukhim R, Bi WL, Ligon KL, Wen PY. Clinical utility of targeted next-generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making. Neuro Oncol. 2022 07 01; 24(7):1140-1149. PMID: 34878541; PMCID: PMC9248387.
    Citations: 4     Fields:    Translation:Humans
  9. Yearley AG, Iorgulescu JB, Chiocca EA, Peruzzi PP, Smith TR, Reardon DA, Mooney MA. The current state of glioma data registries. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac099. PMID: 36196363; PMCID: PMC9521197.
  10. Oliveira G, Stromhaug K, Cieri N, Iorgulescu JB, Klaeger S, Wolff JO, Rachimi S, Chea V, Krause K, Freeman SS, Zhang W, Li S, Braun DA, Neuberg D, Carr SA, Livak KJ, Frederick DT, Fritsch EF, Wind-Rotolo M, Hacohen N, Sade-Feldman M, Yoon CH, Keskin DB, Ott PA, Rodig SJ, Boland GM, Wu CJ. Landscape of helper and regulatory antitumour CD4+ T cells in melanoma. Nature. 2022 05; 605(7910):532-538. PMID: 35508657.
    Citations: 1     Fields:    Translation:HumansCells
  11. Kavouridis VK, Ligon KL, Wen PY, Iorgulescu JB. Survival outcomes associated with MGMT promoter methylation and temozolomide in gliosarcoma patients. J Neurooncol. 2022 May; 158(1):111-116. PMID: 35474499.
    Citations:    Fields:    Translation:HumansCells
  12. Lamba N, Groves A, Torre M, Yeo KK, Iorgulescu JB. The epidemiology of primary and metastatic brain tumors in infancy through childhood. J Neurooncol. 2022 Jan; 156(2):419-429. PMID: 35037155.
    Citations: 1     Fields:    Translation:Humans
  13. Lamba N, McAvoy M, Kavouridis VK, Smith TR, Touat M, Reardon DA, Iorgulescu JB. Short-term outcomes associated with temozolomide or PCV chemotherapy for 1p/19q-codeleted WHO grade 3 oligodendrogliomas: A national evaluation. Neurooncol Pract. 2022 May; 9(3):201-207. PMID: 35601971; PMCID: PMC9113268.
    Citations: 1     
  14. Gartland RM, Myers LC, Iorgulescu JB, Nguyen AT, Yu-Moe CW, Falcone B, Mitchell R, Kachalia A, Mort E. Body of Evidence: Do Autopsy Findings Impact Medical Malpractice Claim Outcomes? J Patient Saf. 2021 12 01; 17(8):576-582. PMID: 32209947; PMCID: PMC7508944.
    Citations: 1     Fields:    Translation:Humans
  15. Castellanos LE, Gutierrez C, Smith T, Laws ER, Iorgulescu JB. Epidemiology of common and uncommon adult pituitary tumors in the U.S. according to the 2017 World Health Organization classification. Pituitary. 2022 Feb; 25(1):201-209. PMID: 34580820.
    Citations: 1     Fields:    Translation:Humans
  16. Chen X, Lim-Fat MJ, Qin L, Li A, Bryant A, Bay CP, Gao L, Miskin N, Liu Z, Iorgulescu JB, Xu X, Reardon DA, Young GS. A Comparative Retrospective Study of Immunotherapy RANO Versus Standard RANO Criteria in Glioblastoma Patients Receiving Immune Checkpoint Inhibitor Therapy. Front Oncol. 2021; 11:679331. PMID: 34249718; PMCID: PMC8268004.
    Citations: 1     
  17. Boaro A, Kavouridis VK, Siddi F, Mezzalira E, Harary M, Iorgulescu JB, Reardon DA, Smith TR. Improved outcomes associated with maximal extent of resection for butterfly glioblastoma: insights from institutional and national data. Acta Neurochir (Wien). 2021 07; 163(7):1883-1894. PMID: 33871698.
    Citations: 2     Fields:    Translation:HumansCells
  18. Lim-Fat MJ, Song KW, Iorgulescu JB, Andersen BM, Forst DA, Jordan JT, Gerstner ER, Reardon DA, Wen PY, Arrillaga-Romany I. Clinical, radiological and genomic features and targeted therapy in BRAF V600E mutant adult glioblastoma. J Neurooncol. 2021 May; 152(3):515-522. PMID: 33646525; PMCID: PMC8415171.
    Citations: 2     Fields:    Translation:Humans
  19. Hu Z, Leet DE, Allesøe RL, Oliveira G, Li S, Luoma AM, Liu J, Forman J, Huang T, Iorgulescu JB, Holden R, Sarkizova S, Gohil SH, Redd RA, Sun J, Elagina L, Giobbie-Hurder A, Zhang W, Peter L, Ciantra Z, Rodig S, Olive O, Shetty K, Pyrdol J, Uduman M, Lee PC, Bachireddy P, Buchbinder EI, Yoon CH, Neuberg D, Pentelute BL, Hacohen N, Livak KJ, Shukla SA, Olsen LR, Barouch DH, Wucherpfennig KW, Fritsch EF, Keskin DB, Wu CJ, Ott PA. Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma. Nat Med. 2021 03; 27(3):515-525. PMID: 33479501; PMCID: PMC8273876.
    Citations: 53     Fields:    Translation:Humans
  20. Castellanos LE, Misra M, Smith TR, Laws ER, Iorgulescu JB. The epidemiology and management patterns of pediatric pituitary tumors in the United States. Pituitary. 2021 Jun; 24(3):412-419. PMID: 33433891.
    Citations: 2     Fields:    Translation:Humans
  21. Gohil SH, Iorgulescu JB, Braun DA, Keskin DB, Livak KJ. Applying high-dimensional single-cell technologies to the analysis of cancer immunotherapy. Nat Rev Clin Oncol. 2021 04; 18(4):244-256. PMID: 33277626; PMCID: PMC8415132.
    Citations: 37     Fields:    Translation:HumansCells
  22. Lamba N, Chukwueke UN, Smith TR, Ligon KL, Aizer A, Reardon DA, Iorgulescu JB. Socioeconomic Disparities Associated With MGMT Promoter Methylation Testing for Patients With Glioblastoma. JAMA Oncol. 2020 12 01; 6(12):1972-1974. PMID: 33090181.
    Citations: 9     Fields:    Translation:HumansCells
  23. Iorgulescu JB, Gokhale PC, Speranza MC, Eschle BK, Poitras MJ, Wilkens MK, Soroko KM, Chhoeu C, Knott A, Gao Y, Lim-Fat MJ, Baker GJ, Bonal DM, Nguyen QD, Grant GRL, Ligon KL, Sorger PK, Chiocca EA, Anderson AC, Kirschmeier PT, Sharpe AH, Freeman GJ, Reardon DA. Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma. Clin Cancer Res. 2021 01 01; 27(1):276-287. PMID: 33239433; PMCID: PMC8034990.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  24. Harary M, Tung JK, Sood S, Corrales CE, Smith T, Iorgulescu JB. Benign purely intraosseous meningioma of the skull: Diagnosis and surgical outcomes. J Clin Neurosci. 2020 Dec; 82(Pt A):36-42. PMID: 33317736.
    Citations: 1     Fields:    Translation:Humans
  25. Gupta S, Iorgulescu JB, Hoffman S, Catalino M, Bernstock JD, Chua M, Segar DJ, Fandino LB, Laws ER, Smith TR. The diagnosis and management of primary and iatrogenic soft tissue sarcomas of the sella. Pituitary. 2020 Oct; 23(5):558-572. PMID: 32613388.
    Citations: 2     Fields:    Translation:Humans
  26. Hulsbergen AFC, Mammi M, Nagtegaal SHJ, Lak AM, Kavouridis V, Smith TR, Iorgulescu JB, Mekary RA, Verhoeff JJC, Broekman MLD, Phillips JG. Programmed Death Receptor Ligand One Expression May Independently Predict Survival in Patients With Non-Small Cell Lung Carcinoma Brain Metastases Receiving Immunotherapy. Int J Radiat Oncol Biol Phys. 2020 09 01; 108(1):258-267. PMID: 32335185.
    Citations: 5     Fields:    Translation:Humans
  27. Touat M, Li YY, Boynton AN, Spurr LF, Iorgulescu JB, Bohrson CL, Cortes-Ciriano I, Birzu C, Geduldig JE, Pelton K, Lim-Fat MJ, Pal S, Ferrer-Luna R, Ramkissoon SH, Dubois F, Bellamy C, Currimjee N, Bonardi J, Qian K, Ho P, Malinowski S, Taquet L, Jones RE, Shetty A, Chow KH, Sharaf R, Pavlick D, Albacker LA, Younan N, Baldini C, Verreault M, Giry M, Guillerm E, Ammari S, Beuvon F, Mokhtari K, Alentorn A, Dehais C, Houillier C, Laigle-Donadey F, Psimaras D, Lee EQ, Nayak L, McFaline-Figueroa JR, Carpentier A, Cornu P, Capelle L, Mathon B, Barnholtz-Sloan JS, Chakravarti A, Bi WL, Chiocca EA, Fehnel KP, Alexandrescu S, Chi SN, Haas-Kogan D, Batchelor TT, Frampton GM, Alexander BM, Huang RY, Ligon AH, Coulet F, Delattre JY, Hoang-Xuan K, Meredith DM, Santagata S, Duval A, Sanson M, Cherniack AD, Wen PY, Reardon DA, Marabelle A, Park PJ, Idbaih A, Beroukhim R, Bandopadhayay P, Bielle F, Ligon KL. Mechanisms and therapeutic implications of hypermutation in gliomas. Nature. 2020 04; 580(7804):517-523. PMID: 32322066; PMCID: PMC8235024.
    Citations: 130     Fields:    Translation:HumansAnimalsCells
  28. Helgager J, Pytel P, Vasudevaraja V, Lee EQ, Snuderl M, Iorgulescu JB, Ligon KL. WNT-Activated Medulloblastomas With Hybrid Molecular Subtypes. JCO Precis Oncol. 2020; 4. PMID: 32923883.
    Citations: 2     Fields:    
  29. Harary M, Kavouridis VK, Torre M, Zaidi HA, Chukwueke UN, Reardon DA, Smith TR, Iorgulescu JB. Predictors and early survival outcomes of maximal resection in WHO grade II 1p/19q-codeleted oligodendrogliomas. Neuro Oncol. 2020 03 05; 22(3):369-380. PMID: 31538193.
    Citations: 3     Fields:    Translation:HumansCells
  30. Kavouridis VK, Boaro A, Dorr J, Cho EY, Iorgulescu JB, Reardon DA, Arnaout O, Smith TR. Contemporary assessment of extent of resection in molecularly defined categories of diffuse low-grade glioma: a volumetric analysis. J Neurosurg. 2019 Oct 25; 1-11. PMID: 31653812; PMCID: PMC7348099.
    Citations: 9     Fields:    
  31. Guièze R, Liu VM, Rosebrock D, Jourdain AA, Hernández-Sánchez M, Martinez Zurita A, Sun J, Ten Hacken E, Baranowski K, Thompson PA, Heo JM, Cartun Z, Aygün O, Iorgulescu JB, Zhang W, Notarangelo G, Livitz D, Li S, Davids MS, Biran A, Fernandes SM, Brown JR, Lako A, Ciantra ZB, Lawlor MA, Keskin DB, Udeshi ND, Wierda WG, Livak KJ, Letai AG, Neuberg D, Harper JW, Carr SA, Piccioni F, Ott CJ, Leshchiner I, Johannessen CM, Doench J, Mootha VK, Getz G, Wu CJ. Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies. Cancer Cell. 2019 10 14; 36(4):369-384.e13. PMID: 31543463.
    Citations: 91     Fields:    Translation:HumansAnimalsCells
  32. Iorgulescu JB, Freedman RA, Lester SC, Mittendorf EA, Brock JE. 21-Gene Recurrence Score Adds Significant Value for Grade 3 Breast Cancers: Results From a National Cohort. JCO Precis Oncol. 2019; 3. PMID: 32457931; PMCID: PMC7250459.
    Citations: 1     Fields:    
  33. Kavouridis VK, Harary M, Hulsbergen AFC, Lo YT, Reardon DA, Aizer AA, Iorgulescu JB, Smith TR. Survival and prognostic factors in surgically treated brain metastases. J Neurooncol. 2019 Jun; 143(2):359-367. PMID: 30989623.
    Citations: 13     Fields:    Translation:Humans
  34. Harary M, Reardon DA, Iorgulescu JB. Efficacy and safety of immune checkpoint blockade for brain metastases. CNS Oncol. 2019 06; 8(2):CNS33. PMID: 30854898; PMCID: PMC6713022.
    Citations: 6     Fields:    Translation:Humans
  35. Iorgulescu JB, Torre M, Harary M, Smith TR, Aizer AA, Reardon DA, Barnholtz-Sloan JS, Perry A. The Misclassification of Diffuse Gliomas: Rates and Outcomes. Clin Cancer Res. 2019 04 15; 25(8):2656-2663. PMID: 30635340; PMCID: PMC6467794.
    Citations: 15     Fields:    Translation:Humans
  36. Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA. Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. Nature. 2019 01; 565(7738):234-239. PMID: 30568305.
    Citations: 410     Fields:    Translation:HumansCellsCTClinical Trials
  37. Iorgulescu JB, Braun D, Oliveira G, Keskin DB, Wu CJ. Acquired mechanisms of immune escape in cancer following immunotherapy. Genome Med. 2018 11 22; 10(1):87. PMID: 30466478.
    Citations: 22     Fields:    Translation:Humans
  38. Giantini Larsen AM, Cote DJ, Zaidi HA, Bi WL, Schmitt PJ, Iorgulescu JB, Miller MB, Smith TR, Lopes MB, Jane JA, Laws ER. Spindle cell oncocytoma of the pituitary gland. J Neurosurg. 2018 10 19; 131(2):517-525. PMID: 30485213; PMCID: PMC6486883.
    Citations: 8     Fields:    Translation:Humans
  39. Gupta S, Ahmed AK, Bi WL, Dawood HY, Iorgulescu JB, Corrales CE, Dunn IF, Smith TR. Predicting Readmission and Reoperation for Benign Cranial Nerve Neoplasms: A Nationwide Analysis. World Neurosurg. 2019 Jan; 121:e223-e229. PMID: 30261394.
    Citations: 2     Fields:    Translation:Humans
  40. Dobry AS, Zogg CK, Hodi FS, Smith TR, Ott PA, Iorgulescu JB. Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies. Cancer Immunol Immunother. 2018 Dec; 67(12):1833-1844. PMID: 30191256; PMCID: PMC6249064.
    Citations: 24     Fields:    Translation:Humans
  41. Iorgulescu JB, Reardon DA, Chiocca EA, Wu CJ. Immunotherapy for glioblastoma: going viral. Nat Med. 2018 08; 24(8):1094-1096. PMID: 30082860.
    Citations: 10     Fields:    Translation:Humans
  42. Iorgulescu JB, Harary M, Zogg CK, Ligon KL, Reardon DA, Hodi FS, Aizer AA, Smith TR. Improved Risk-Adjusted Survival for Melanoma Brain Metastases in the Era of Checkpoint Blockade Immunotherapies: Results from a National Cohort. Cancer Immunol Res. 2018 09; 6(9):1039-1045. PMID: 30002157.
    Citations: 32     Fields:    Translation:Humans
  43. Abd-El-Barr MM, Huang KT, Moses ZB, Iorgulescu JB, Chi JH. Recent advances in intradural spinal tumors. Neuro Oncol. 2018 05 18; 20(6):729-742. PMID: 29216380; PMCID: PMC5961256.
    Citations: 14     Fields:    Translation:Humans
  44. Iorgulescu JB, Ferris S, Agarwal A, Casavilca Zambrano S, Hill DA, Schmidt R, Perry A. Non-meningothelial meningeal tumours with meningioangiomatosis-like pattern of spread. Neuropathol Appl Neurobiol. 2018 12; 44(7):743-746. PMID: 29495087; PMCID: PMC6119531.
    Citations:    Fields:    Translation:Humans
  45. Iorgulescu JB, Van Ziffle J, Stevers M, Grenert JP, Bastian BC, Chavez L, Stichel D, Buchhalter I, Samuel D, Nicolaides T, Banerjee A, Mueller S, Gupta N, Tihan T, Bollen AW, Northcott PA, Kool M, Pfister S, Korshunov A, Perry A, Solomon DA. Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation. Acta Neuropathol. 2018 04; 135(4):635-638. PMID: 29435664; PMCID: PMC6078208.
    Citations: 14     Fields:    Translation:HumansCells
  46. Zuckerman SL, Kreines F, Powers A, Iorgulescu JB, Elder JB, Bilsky MH, Laufer I. Stabilization of Tumor-Associated Craniovertebral Junction Instability: Indications, Operative Variables, and Outcomes. Neurosurgery. 2017 Aug 01; 81(2):251-258. PMID: 28368478.
    Citations: 5     Fields:    Translation:Humans
  47. Maggio DM, Singh A, Iorgulescu JB, Bleicher DH, Ghosh M, Lopez MM, Tuesta LM, Flora G, Dietrich WD, Pearse DD. Identifying the Long-Term Role of Inducible Nitric Oxide Synthase after Contusive Spinal Cord Injury Using a Transgenic Mouse Model. Int J Mol Sci. 2017 Jan 25; 18(2). PMID: 28125047.
    Citations: 2     Fields:    Translation:AnimalsCells
  48. Karhade AV, Fandino L, Gupta S, Cote DJ, Iorgulescu JB, Broekman ML, Aglio LS, Dunn IF, Smith TR. Impact of operative length on post-operative complications in meningioma surgery: a NSQIP analysis. J Neurooncol. 2017 01; 131(1):59-67. PMID: 27864707.
    Citations: 6     Fields:    Translation:Humans
  49. Xu R, Shimizu F, Hovinga K, Beal K, Karimi S, Droms L, Peck KK, Gutin P, Iorgulescu JB, Kaley T, DeAngelis L, Pentsova E, Nolan C, Grommes C, Chan T, Bobrow D, Hormigo A, Cross JR, Wu N, Takebe N, Panageas K, Ivy P, Supko JG, Tabar V, Omuro A. Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial. Clin Cancer Res. 2016 Oct 01; 22(19):4786-4796. PMID: 27154916.
    Citations: 47     Fields:    Translation:HumansCellsCTClinical Trials
  50. Iorgulescu JB, Ivan ME, Safaee M, Parsa AT. The limited capacity of malignant glioma-derived exosomes to suppress peripheral immune effectors. J Neuroimmunol. 2016 Jan 15; 290:103-8. PMID: 26711578.
    Citations: 17     Fields:    Translation:HumansCells
  51. Iorgulescu JB, Patel SP, Louro J, Andrade CM, Sanchez AR, Pearse DD. Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats. Neural Plast. 2015; 2015:186385. PMID: 26550496; PMCID: PMC4621347.
    Citations: 6     Fields:    Translation:AnimalsCells
  52. McCrea HJ, Bander ED, Venn RA, Reiner AS, Iorgulescu JB, Puchi LA, Schaefer PM, Cederquist G, Greenfield JP. Sex, Age, Anatomic Location, and Extent of Resection Influence Outcomes in Children With High-grade Glioma. Neurosurgery. 2015 Sep; 77(3):443-52; discussion 452-3. PMID: 26083157.
    Citations: 20     Fields:    Translation:Humans
  53. Walcott BP, Iorgulescu JB, Stapleton CJ, Kamel H. Incidence, Timing, and Predictors of Delayed Shunting for Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage. Neurocrit Care. 2015 Aug; 23(1):54-8. PMID: 25519720.
    Citations: 7     Fields:    Translation:Humans
  54. Luther N, Iorgulescu JB, Geannette C, Gebhard H, Saleh T, Tsiouris AJ, Härtl R. Comparison of navigated versus non-navigated pedicle screw placement in 260 patients and 1434 screws: screw accuracy, screw size, and the complexity of surgery. J Spinal Disord Tech. 2015 Jun; 28(5):E298-303. PMID: 23511642.
    Citations: 24     Fields:    Translation:Humans
  55. Moussazadeh N, Kulwin C, Anand VK, Ting JY, Gamss C, Iorgulescu JB, Tsiouris AJ, Cohen-Gadol AA, Schwartz TH. Endoscopic endonasal resection of skull base chondrosarcomas: technique and early results. J Neurosurg. 2015 Apr; 122(4):735-42. PMID: 25594323.
    Citations: 6     Fields:    Translation:Humans
  56. Ivan ME, Iorgulescu JB, El-Sayed I, McDermott MW, Parsa AT, Pletcher SD, Jahangiri A, Wagner J, Aghi MK. Risk factors for postoperative cerebrospinal fluid leak and meningitis after expanded endoscopic endonasal surgery. J Clin Neurosci. 2015 Jan; 22(1):48-54. PMID: 25439754.
    Citations: 30     Fields:    Translation:Humans
  57. Vera E, Iorgulescu JB, Raper DM, Madhavan K, Lally BE, Morcos J, Elhammady S, Sherman J, Komotar RJ. A review of stereotactic radiosurgery practice in the management of skull base meningiomas. J Neurol Surg B Skull Base. 2014 Jun; 75(3):152-8. PMID: 25072008.
    Citations: 10     
  58. Amankulor NM, Xu R, Iorgulescu JB, Chapman T, Reiner AS, Riedel E, Lis E, Yamada Y, Bilsky M, Laufer I. The incidence and patterns of hardware failure after separation surgery in patients with spinal metastatic tumors. Spine J. 2014 Sep 01; 14(9):1850-9. PMID: 24216397.
    Citations: 29     Fields:    Translation:Humans
  59. Iorgulescu JB, Laufer I, Hameed M, Boland P, Yamada Y, Lis E, Bilsky M. Benign notochordal cell tumors of the spine: natural history of 8 patients with histologically confirmed lesions. Neurosurgery. 2013 Sep; 73(3):411-6. PMID: 23719057.
    Citations: 7     Fields:    Translation:Humans
  60. Laufer I, Iorgulescu JB, Chapman T, Lis E, Shi W, Zhang Z, Cox BW, Yamada Y, Bilsky MH. Local disease control for spinal metastases following "separation surgery" and adjuvant hypofractionated or high-dose single-fraction stereotactic radiosurgery: outcome analysis in 186 patients. J Neurosurg Spine. 2013 Mar; 18(3):207-14. PMID: 23339593.
    Citations: 105     Fields:    Translation:Humans
  61. Komotar RJ, Iorgulescu JB, Raper DM, Holland EC, Beal K, Bilsky MH, Brennan CW, Tabar V, Sherman JH, Yamada Y, Gutin PH. The role of radiotherapy following gross-total resection of atypical meningiomas. J Neurosurg. 2012 Oct; 117(4):679-86. PMID: 22920955.
    Citations: 43     Fields:    Translation:Humans
  62. Siu A, Wind JJ, Iorgulescu JB, Chan TA, Yamada Y, Sherman JH. Radiation necrosis following treatment of high grade glioma--a review of the literature and current understanding. Acta Neurochir (Wien). 2012 Feb; 154(2):191-201; discussion 201. PMID: 22130634.
    Citations: 59     Fields:    Translation:HumansCellsPHPublic Health
  63. Shah AH, Madhavan K, Heros D, Raper DM, Iorgulescu JB, Lally BE, Komotar RJ. The management of incidental low-grade gliomas using magnetic resonance imaging: systematic review and optimal treatment paradigm. Neurosurg Focus. 2011 Dec; 31(6):E12. PMID: 22133169.
    Citations: 9     Fields:    Translation:Humans
  64. Komotar RJ, Raper DM, Starke RM, Iorgulescu JB, Gutin PH. Prophylactic antiepileptic drug therapy in patients undergoing supratentorial meningioma resection: a systematic analysis of efficacy. J Neurosurg. 2011 Sep; 115(3):483-90. PMID: 21639698.
    Citations: 16     Fields:    Translation:Humans
  65. Luther N, Rubens E, Sethi N, Kandula P, Labar DR, Harden C, Perrine K, Christos PJ, Iorgulescu JB, Lancman G, Schaul NS, Kolesnik DV, Nouri S, Dawson A, Tsiouris AJ, Schwartz TH. The value of intraoperative electrocorticography in surgical decision making for temporal lobe epilepsy with normal MRI. Epilepsia. 2011 May; 52(5):941-8. PMID: 21480886.
    Citations: 8     Fields:    Translation:Humans
  66. Pearse DD, Tian RX, Nigro J, Iorgulescu JB, Puzis L, Jaimes EA. Angiotensin II increases the expression of the transcription factor ETS-1 in mesangial cells. Am J Physiol Renal Physiol. 2008 May; 294(5):F1094-100. PMID: 18337545.
    Citations: 16     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.