Harvard Catalyst Profiles

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Hiroshi Sasaki, Ph.D.


The University of Tokyo, JapanPh.D.03/2011Structural Biology
The University of Tokyo, JapanM.S.03/2007Biophysics and Biochemistry
The University of Tokyo, JapanB.S.03/2005Biophysics and Biochemistry

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Takeda N, Fukuda M, Sasaki H, Sugiyama K. The Effects of Antiglaucoma Ophthalmic Solutions on the Cornea Revealed by a Corneal Electrical Resistance Device. J Ocul Pharmacol Ther. 2021 03; 37(2):97-103. PMID: 33439755.
    Citations:    Fields:    
  2. Hashimoto M, Sasaki H. Cell competition controls differentiation in mouse embryos and stem cells. Curr Opin Cell Biol. 2020 12; 67:1-8. PMID: 32763500.
    Citations:    Fields:    Translation:AnimalsCells
  3. Minev D, Guerra R, Kishi JY, Smith C, Krieg E, Said K, Hornick A, Sasaki HM, Filsinger G, Beliveau BJ, Yin P, Church GM, Shih WM. Rapid in vitro production of single-stranded DNA. Nucleic Acids Res. 2019 12 16; 47(22):11956-11962. PMID: 31713635.
    Citations: 4     Fields:    Translation:HumansCells
  4. Ezawa M, Sasaki H, Yamada K, Takano H, Iwasaka T, Nakao Y, Yokochi T, Okamoto A. Long term outcomes from lymphatic venous anastomosis after total hysterectomy to prevent postoperative lymphedema in lower limb. BMC Surg. 2019 Nov 26; 19(1):177. PMID: 31771562.
    Citations: 1     Fields:    Translation:Humans
  5. Hashimoto M, Sasaki H. Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells. Dev Cell. 2019 07 22; 50(2):139-154.e5. PMID: 31204175.
    Citations: 21     Fields:    Translation:AnimalsCells
  6. Kishi JY, Lapan SW, Beliveau BJ, West ER, Zhu A, Sasaki HM, Saka SK, Wang Y, Cepko CL, Yin P. SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues. Nat Methods. 2019 06; 16(6):533-544. PMID: 31110282.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  7. Nir G, Farabella I, Pérez Estrada C, Ebeling CG, Beliveau BJ, Sasaki HM, Lee SD, Nguyen SC, McCole RB, Chattoraj S, Erceg J, AlHaj Abed J, Martins NMC, Nguyen HQ, Hannan MA, Russell S, Durand NC, Rao SSP, Kishi JY, Soler-Vila P, Di Pierro M, Onuchic JN, Callahan SP, Schreiner JM, Stuckey JA, Yin P, Aiden EL, Marti-Renom MA, Wu CT. Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling. PLoS Genet. 2018 12; 14(12):e1007872. PMID: 30586358.
    Citations: 54     Fields:    Translation:HumansCells
  8. Kamura K, Shin J, Kiyonari H, Abe T, Shioi G, Fukuhara A, Sasaki H. Obesity in Yap transgenic mice is associated with TAZ downregulation. Biochem Biophys Res Commun. 2018 11 02; 505(3):951-957. PMID: 30309656.
    Citations: 3     Fields:    Translation:AnimalsCells
  9. Beliveau BJ, Kishi JY, Nir G, Sasaki HM, Saka SK, Nguyen SC, Wu CT, Yin P. OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):E2183-E2192. PMID: 29463736.
    Citations: 35     Fields:    Translation:HumansAnimals
  10. Sasaki HM, Tadakuma H, Tomari Y. Single-Molecule Analysis for RISC Assembly and Target Cleavage. Methods Mol Biol. 2018; 1680:145-164. PMID: 29030847.
    Citations:    Fields:    
  11. Schueder F, Lara-Gutiérrez J, Beliveau BJ, Saka SK, Sasaki HM, Woehrstein JB, Strauss MT, Grabmayr H, Yin P, Jungmann R. Multiplexed 3D super-resolution imaging of whole cells using spinning disk confocal microscopy and DNA-PAINT. Nat Commun. 2017 12 12; 8(1):2090. PMID: 29233999.
    Citations: 27     Fields:    Translation:HumansCells
  12. Yao C, Sasaki HM, Ueda T, Tomari Y, Tadakuma H. Single-Molecule Analysis of the Target Cleavage Reaction by the Drosophila RNAi Enzyme Complex. Mol Cell. 2015 Jul 02; 59(1):125-32. PMID: 26140368.
    Citations: 16     Fields:    Translation:AnimalsCells
  13. Iwasaki S, Sasaki HM, Sakaguchi Y, Suzuki T, Tadakuma H, Tomari Y. Defining fundamental steps in the assembly of the Drosophila RNAi enzyme complex. Nature. 2015 May 28; 521(7553):533-6. PMID: 25822791.
    Citations: 46     Fields:    Translation:AnimalsCells
  14. Wicklow E, Blij S, Frum T, Hirate Y, Lang RA, Sasaki H, Ralston A. HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. PLoS Genet. 2014 Oct; 10(10):e1004618. PMID: 25340657.
    Citations: 56     Fields:    Translation:AnimalsCells
  15. Sasaki HM, Tomari Y. The true core of RNA silencing revealed. Nat Struct Mol Biol. 2012 Jul 05; 19(7):657-60. PMID: 22767235.
    Citations: 9     Fields:    Translation:Humans
  16. Sugimoto K, Hashimoto T, Takahashi E, Saito Y, Haino T, Sasaki H, Kusuhara K, Tanaka T. Cancellation of in vitro fertilization treatment cycles predicts treatment outcome in female infertility patients aged 40 years or older. Reprod Med Biol. 2011 09; 10(3):179-184. PMID: 29662356.
  17. Sansores-Garcia L, Bossuyt W, Wada K, Yonemura S, Tao C, Sasaki H, Halder G. Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J. 2011 May 10; 30(12):2325-35. PMID: 21556047.
    Citations: 199     Fields:    Translation:HumansAnimalsCells
  18. Oki K, Sakamoto K, Kobayashi T, Sasaki HM, Yokoyama S. Transplantation of a tyrosine editing domain into a tyrosyl-tRNA synthetase variant enhances its specificity for a tyrosine analog. Proc Natl Acad Sci U S A. 2008 Sep 09; 105(36):13298-303. PMID: 18765802.
    Citations: 13     Fields:    Translation:Cells
  19. Sasaki HM, Sekine S, Sengoku T, Fukunaga R, Hattori M, Utsunomiya Y, Kuroishi C, Kuramitsu S, Shirouzu M, Yokoyama S. Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase. Proc Natl Acad Sci U S A. 2006 Oct 03; 103(40):14744-9. PMID: 17003130.
    Citations: 15     Fields:    Translation:Cells
  20. Dai P, Shinagawa T, Nomura T, Harada J, Kaul SC, Wadhwa R, Khan MM, Akimaru H, Sasaki H, Colmenares C, Ishii S. Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3. Genes Dev. 2002 Nov 15; 16(22):2843-8. PMID: 12435627.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.