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Hanny Al-Samkari, M.D.

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Biography
University of Dayton, Dayton, OHB.S., B.A.05/2007Biology, Chemistry
Washington University School of Medicine, St. Louis, MOM.D.05/2011Medicine
Hospital of the University of Pennsylvania, Philadelphia, PA06/2014Internal Medicine Residency
Hospital of the University of Pennsylvania, Philadelphia, PA06/2015Chief Medical Resident
Dana-Farber Cancer Institute/Massachusetts General Hospital/Brigham & Women's Hospital, Boston, MA06/2018Hematology & Medical Oncology Fellowship
2007
John E. Dlugos, Jr. Memoral Award of Excellence in Biology
2007
Montgomery County Medical Society Award
2007
Carl I. Michaelis Chemistry Scholarship Award
2007
Department of Chemistry Teaching Excellence Award
2007
John C. Johnson Research Award
2008
Antoinette Frances Dames Award in Cell Biology and Physiology
2008
Edmund V. Cowdry Prize in Histology
2010
Doctor Richard S. Brookings Medical School Prize
2010
Alpha Omega Alpha, Honor Medical Society
2011
Missouri State Medical Association Award
2011
American College of Physicians Michael M. Karl, M.D. Book Award

Mentoring
Available: 07/06/18, Expires: 07/01/21

Utilizing the Research Patient Data Registry (RPDR) Database at Partners, an incredibly powerful clinical data resource unique to Harvard, as well as other valuable databases available within the Massachusetts General Hospital Division of Hematology & Oncology, I will work with the mentee (medical student or resident) to design, execute, and publish a clinical research project in the field of Hematology. Projects will be designed to fit your goals and the time you have available to you (which can be as little as one month) and answer important questions. As your faculty mentor on this scholarly project, upon its completion you can expect at least one and possibly multiple publications on which you will be first author. Depending on the timing of the research, presentation of an abstract at a national meeting prior to submitting the work for publication is also a possibility. As your mentor, I will guide you through the research process, which will include weekly in-person meetings with you to facilitate consistent progress and availability by phone or text message to answer questions and troubleshoot issues. You will have the benefit of a mentor who has the experience necessary for your success and very importantly the time to spend on you to ensure your academic development and the completion of your project. Those interested should contact me by email to express interest and schedule an in-person or telephone meeting at least 6 weeks prior to the block of time intended for performing the research itself (if at all possible), as IRB approval takes approximately 5 weeks.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. (AL-SAMKARI, HANNY) Jul 1, 2018 - Jun 30, 2020
    NATIONAL HEMOPHILIA FOUNDATION
    NHF-SHIRE CLINICAL FELLOWSHIP

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Virk ZM, Kuter DJ, Al-Samkari H. An evaluation of avatrombopag for the treatment of thrombocytopenia. Expert Opin Pharmacother. 2020 Oct 23. PMID: 33095074.
    Citations:    Fields:    
  2. Al-Samkari H, Croteau SE. Beliefs, opinions and impact of emicizumab in haemophilia A patients: A National US Survey Study. Haemophilia. 2020 Sep 08. PMID: 32897603.
    Citations:    Fields:    
  3. Faughnan ME, Mager JJ, Hetts SW, Palda VA, Lang-Robertson K, Buscarini E, Deslandres E, Kasthuri RS, Lausman A, Poetker D, Ratjen F, Chesnutt MS, Clancy M, Whitehead KJ, Al-Samkari H, Chakinala M, Conrad M, Cortes D, Crocione C, Darling J, de Gussem E, Derksen C, Dupuis-Girod S, Foy P, Geisthoff U, Gossage JR, Hammill A, Heimdal K, Henderson K, Iyer VN, Kjeldsen AD, Komiyama M, Korenblatt K, McDonald J, McMahon J, McWilliams J, Meek ME, Mei-Zahav M, Olitsky S, Palmer S, Pantalone R, Piccirillo JF, Plahn B, Porteous MEM, Post MC, Radovanovic I, Rochon PJ, Rodriguez-Lopez J, Sabba C, Serra M, Shovlin C, Sprecher D, White AJ, Winship I, Zarrabeitia R. Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia. Ann Intern Med. 2020 Sep 08. PMID: 32894695.
    Citations:    Fields:    
  4. Al-Samkari H, Song F, Van Cott EM, Kuter DJ, Rosovsky R. Evaluation of the prothrombin fragment 1.2 in patients with coronavirus disease 2019 (COVID-19). Am J Hematol. 2020 Aug 11. PMID: 32780525.
    Citations:    Fields:    
  5. Al-Samkari H, Karp Leaf RS, Dzik WH, Carlson JCT, Fogerty AE, Waheed A, Goodarzi K, Bendapudi PK, Bornikova L, Gupta S, Leaf DE, Kuter DJ, Rosovsky RP. COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection. Blood. 2020 07 23; 136(4):489-500. PMID: 32492712.
    Citations: 25     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  6. Al-Samkari H, Goodarzi K. An Eltrombopag Red (Plasma) Alert. Acta Haematol. 2020 Jul 22; 1-2. PMID: 32702690.
    Citations:    Fields:    
  7. Leiva O, Connors JM, Al-Samkari H. Impact of Tumor Genomic Mutations on Thrombotic Risk in Cancer Patients. Cancers (Basel). 2020 Jul 19; 12(7). PMID: 32707653.
    Citations:    
  8. Al-Samkari H, Kasthuri RS, Parambil JG, Albitar HA, Almodallal YA, Vázquez C, Serra MM, Dupuis-Girod S, Wilsen CB, McWilliams JP, Fountain EH, Gossage JR, Weiss CR, Latif MA, Issachar A, Mei-Zahav M, Meek ME, Conrad M, Rodriguez-Lopez J, Kuter DJ, Iyer VN. An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study. Haematologica. 2020 Jul 16. PMID: 32675221.
    Citations:    Fields:    
  9. Song AB, Kuter DJ, Al-Samkari H. Characterization of the rate, predictors, and thrombotic complications of thrombocytosis in iron deficiency anemia. Am J Hematol. 2020 Jul 03. PMID: 32619079.
    Citations:    Fields:    
  10. Al-Samkari H, van Beers EJ, Morton DH, Barcellini W, Eber SW, Glader B, Yaish HM, Chonat S, Kuo KHM, Kollmar N, Despotovic JM, Pospíšilová D, Knoll CM, Kwiatkowski JL, Pastore YD, Thompson AA, Wlodarski MW, Ravindranath Y, Rothman JA, Wang H, Holzhauer S, Breakey VR, Verhovsek MM, Kunz J, Sheth S, Sharma M, Rose MJ, Bradeen HA, McNaull MN, Addonizio K, Al-Sayegh H, London WB, Grace RF. Characterization of the severe phenotype of pyruvate kinase deficiency. Am J Hematol. 2020 Jul 03. PMID: 32619047.
    Citations:    Fields:    
  11. Leaf RK, Al-Samkari H, Brenner SK, Gupta S, Leaf DE. ABO Phenotype and Death in Critically Ill Patients with COVID-19. Br J Haematol. 2020 Jul 01. PMID: 32609874.
    Citations: 2     Fields:    
  12. Cheloff AZ, Al-Samkari H. Emapalumab for the treatment of hemophagocytic lymphohistiocytosis. Drugs Today (Barc). 2020 Jul; 56(7):439-446. PMID: 32648854.
    Citations:    Fields:    
  13. Cheloff AZ, Kuter DJ, Al-Samkari H. Serum complement levels in immune thrombocytopenia: Characterization and relation to clinical features. Res Pract Thromb Haemost. 2020 Jul; 4(5):807-812. PMID: 32685889.
    Citations:    
  14. Al-Samkari H, Van Beers EJ, Kuo KHM, Barcellini W, Bianchi P, Glenthøj A, Del Mar Mañú Pereira M, Van Wijk R, Glader B, Grace RF. The variable manifestations of disease in pyruvate kinase deficiency and their management. Haematologica. 2020 Jun 05; 105(9):2229-2239. PMID: 33054048.
    Citations:    Fields:    
  15. Al-Samkari H, Parnes AD, Goodarzi K, Weitzman JI, Connors JM, Kuter DJ. A multicenter study of romiplostim for chemotherapy-induced thrombocytopenia in solid tumors and hematologic malignancies. Haematologica. 2020 Jun 04. PMID: 32499239.
    Citations:    Fields:    
  16. Al-Samkari H, Addonizio K, Glader B, Morton DH, Chonat S, Thompson AA, Kuo KHM, Ravindranath Y, Wang H, Rothman JA, Kwiatkowski JL, Kung C, Kosinski PA, Al-Sayegh H, London WB, Grace RF. The pyruvate kinase (PK) to hexokinase enzyme activity ratio and erythrocyte PK protein level in the diagnosis and phenotype of PK deficiency. Br J Haematol. 2020 May 28. PMID: 32463523.
    Citations:    Fields:    
  17. Al-Samkari H, Albitar HA, Olitsky SE, Clancy MS, Iyer VN. An international survey to evaluate systemic bevacizumab for chronic bleeding in hereditary haemorrhagic telangiectasia. Haemophilia. 2020 May 20. PMID: 32432841.
    Citations:    Fields:    
  18. Al-Samkari H, Leiva O, Dagogo-Jack I, Shaw A, Lennerz J, Iafrate AJ, Bendapudi PK, Connors JM. Impact of ALK Rearrangement on Venous and Arterial Thrombotic Risk in NSCLC. J Thorac Oncol. 2020 Sep; 15(9):1497-1506. PMID: 32437899.
    Citations: 1     Fields:    
  19. Al-Samkari H, Ozonoff A, Landschaft A, Kimia R, Harper MB, Croteau SE, Kimia AA. Utility of Blood Cultures and Empiric Antibiotics in Febrile Pediatric Hemophilia Patients With Central Venous Access Devices. Pediatr Emerg Care. 2020 Apr 28. PMID: 32349076.
    Citations:    Fields:    
  20. Al-Samkari H, Grace RF, Kuter DJ. The role of romiplostim for pediatric patients with immune thrombocytopenia. Ther Adv Hematol. 2020; 11:2040620720912992. PMID: 32523658.
    Citations:    
  21. Al-Samkari H, van Beers EJ, Kuo KHM, Barcellini W, Bianchi P, Glenthøj AB, Mañú-Pereira M, van Wijk R, Glader B, Grace RF. The variable manifestations of disease in pyruvate kinase deficiency and their management. Haematologica. 2020 Mar 12. PMID: 32165483.
    Citations:    Fields:    
  22. Al-Samkari H, Patel AA. How to focus our efforts in improving prognostic disclosure in oncology. Cancer. 2020 Jun 01; 126(11):2716-2717. PMID: 32073651.
    Citations:    Fields:    
  23. Boyajian MK, Al-Samkari H, Nguyen DC, Naidoo S, Woo AS. Partial Suture Fusion in Nonsyndromic Single-Suture Craniosynostosis. Cleft Palate Craniofac J. 2020 04; 57(4):499-505. PMID: 32013562.
    Citations:    Fields:    Translation:Humans
  24. Koehl JL, Hayes BD, Al-Samkari H, Rosovsky R. A comprehensive evaluation of apixaban in the treatment of venous thromboembolism. Expert Rev Hematol. 2020 02; 13(2):155-173. PMID: 31958251.
    Citations:    Fields:    
  25. Al-Samkari H, Rosovsky RP, Karp Leaf RS, Smith DB, Goodarzi K, Fogerty AE, Sykes DB, Kuter DJ. A modern reassessment of glycoprotein-specific direct platelet autoantibody testing in immune thrombocytopenia. Blood Adv. 2020 01 14; 4(1):9-18. PMID: 31891657.
    Citations: 7     Fields:    
  26. Bloom PP, Rodriguez-Lopez J, Witkin AS, Al-Samkari H, Kuter DJ, Mojtahed A, Luther J. Ammonia Predicts Hepatic Involvement and Pulmonary Hypertension in Patients With Hereditary Hemorrhagic Telangiectasia. Clin Transl Gastroenterol. 2020 01; 11(1):e00118. PMID: 31977452.
    Citations:    Fields:    
  27. Cai J, Ribkoff J, Olson S, Raghunathan V, Al-Samkari H, DeLoughery TG, Shatzel JJ. The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. Eur J Haematol. 2020 Feb; 104(2):79-87. PMID: 31729076.
    Citations: 4     Fields:    Translation:Humans
  28. Al-Samkari H, Kuter DJ. Immune Thrombocytopenia in Adults: Modern Approaches to Diagnosis and Treatment. Semin Thromb Hemost. 2020 Apr; 46(3):275-288. PMID: 31830764.
    Citations:    Fields:    
  29. Al-Samkari H, Connors JM. Managing the competing risks of thrombosis, bleeding, and anticoagulation in patients with malignancy. Hematology Am Soc Hematol Educ Program. 2019 12 06; 2019(1):71-79. PMID: 31808892.
    Citations:    Fields:    Translation:Humans
  30. Al-Samkari H. Striving for full disclosure-An intergenerational challenge. Cancer. 2020 03 15; 126(6):1150-1151. PMID: 31774549.
    Citations: 2     Fields:    Translation:Humans
  31. Al-Samkari H, Connors JM. Managing the competing risks of thrombosis, bleeding, and anticoagulation in patients with malignancy. Blood Adv. 2019 11 26; 3(22):3770-3779. PMID: 31770442.
    Citations: 4     Fields:    Translation:Humans
  32. Hollenhorst MA, Al-Samkari H, Kuter DJ. Markers of autoimmunity in immune thrombocytopenia: prevalence and prognostic significance. Blood Adv. 2019 11 26; 3(22):3515-3521. PMID: 31730698.
    Citations: 2     Fields:    Translation:Humans
  33. Al-Samkari H, Albitar HA, Olitsky SE, Clancy MS, Iyer VN. Systemic bevacizumab for high-output cardiac failure in hereditary hemorrhagic telangiectasia: an international survey of HHT centers. Orphanet J Rare Dis. 2019 11 14; 14(1):256. PMID: 31727111.
    Citations: 1     Fields:    Translation:Humans
  34. Stern RM, Al-Samkari H, Connors JM. Thrombophilia evaluation in pulmonary embolism. Curr Opin Cardiol. 2019 11; 34(6):603-609. PMID: 31389825.
    Citations: 1     Fields:    Translation:Humans
  35. Al-Samkari H, Kuter DJ. Lactate dehydrogenase is elevated in immune thrombocytopenia and inversely correlates with platelet count. Br J Haematol. 2019 11; 187(3):e61-e64. PMID: 31487388.
    Citations:    Fields:    Translation:Humans
  36. Cheloff AZ, Al-Samkari H. Avatrombopag for the treatment of immune thrombocytopenia and thrombocytopenia of chronic liver disease. J Blood Med. 2019; 10:313-321. PMID: 31565009.
    Citations: 1     
  37. Song AB, Rosovsky RP, Connors JM, Al-Samkari H. Direct oral anticoagulants for treatment and prevention of venous thromboembolism in cancer patients. Vasc Health Risk Manag. 2019; 15:175-186. PMID: 31417269.
    Citations: 1     Fields:    Translation:Humans
  38. Al-Samkari H, Kuter DJ. Optimal use of thrombopoietin receptor agonists in immune thrombocytopenia. Ther Adv Hematol. 2019; 10:2040620719841735. PMID: 31007886.
    Citations: 4     
  39. Al-Samkari H, Shin K, Cardoni L, Pighetti EH, Rits S, McMahon L, Perkins R, Uluer A, Connors JM. Antifibrinolytic Agents for Hemoptysis Management in Adults With Cystic Fibrosis. Chest. 2019 06; 155(6):1226-1233. PMID: 30790551.
    Citations: 2     Fields:    Translation:Humans
  40. Al-Samkari H, Patel AA, Schiano TD, Kuter DJ. Recurrence of Acute Intermittent Porphyria After Liver Transplantation. Ann Intern Med. 2019 06 18; 170(12):904-905. PMID: 30716770.
    Citations:    Fields:    Translation:Humans
  41. Al-Samkari H. Systemic Bevacizumab for Hereditary Hemorrhagic Telangiectasia: Considerations from Observational Studies. Otolaryngol Head Neck Surg. 2019 02; 160(2):368. PMID: 30798765.
    Citations: 1     Fields:    Translation:Humans
  42. Al-Samkari H. Optimal anticoagulant treatment of cancer-associated venous thromboembolism remains unclear. BMJ Evid Based Med. 2019 06; 24(3):115-116. PMID: 30518668.
    Citations:    Fields:    Translation:Humans
  43. Al-Samkari H, Van Cott EM, Kuter DJ. Platelet aggregation response in immune thrombocytopenia patients treated with romiplostim. Ann Hematol. 2019 Mar; 98(3):581-588. PMID: 30446804.
    Citations: 2     Fields:    Translation:Humans
  44. Al-Samkari H. Avatrombopag maleate for the treatment of periprocedural thrombocytopenia in patients with chronic liver disease. Drugs Today (Barc). 2018 Nov; 54(11):647-655. PMID: 30539164.
    Citations: 3     Fields:    Translation:HumansAnimals
  45. Nagrebetsky A, Al-Samkari H, Davis NM, Kuter DJ, Wiener-Kronish JP. Perioperative thrombocytopenia: evidence, evaluation, and emerging therapies. Br J Anaesth. 2019 Jan; 122(1):19-31. PMID: 30579402.
    Citations: 7     Fields:    Translation:Humans
  46. Al-Samkari H, Kritharis A, Rodriguez-Lopez JM, Kuter DJ. Systemic bevacizumab for the treatment of chronic bleeding in hereditary haemorrhagic telangiectasia. J Intern Med. 2019 02; 285(2):223-231. PMID: 30191646.
    Citations: 4     Fields:    Translation:Humans
  47. Al-Samkari H, Snyder GD, Nikiforow S, Tolaney SM, Freedman RA, Losman JA. Haemophagocytic lymphohistiocytosis complicating pembrolizumab treatment for metastatic breast cancer in a patient with the PRF1A91V gene polymorphism. J Med Genet. 2019 01; 56(1):39-42. PMID: 30287596.
    Citations: 1     Fields:    Translation:Humans
  48. Al-Samkari H, Kritharis A, Kuter DJ. Infections and vaccination in hereditary hemorrhagic telangiectasia: microbiological evidence-based considerations. Haematologica. 2018 10; 103(10):e492-e495. PMID: 30270207.
    Citations: 2     Fields:    Translation:Humans
  49. Al-Samkari H, Kuter DJ. Thrombopoietin level predicts response to treatment with eltrombopag and romiplostim in immune thrombocytopenia. Am J Hematol. 2018 12; 93(12):1501-1508. PMID: 30187942.
    Citations: 6     Fields:    Translation:Humans
  50. Al-Samkari H, Connors JM. The Role of Direct Oral Anticoagulants in Treatment of Cancer-Associated Thrombosis. Cancers (Basel). 2018 Aug 15; 10(8). PMID: 30111746.
    Citations: 8     
  51. Al-Samkari H, Kuter DJ. An alternative intermittent eltrombopag dosing protocol for the treatment of chronic immune thrombocytopenia. Br J Clin Pharmacol. 2018 11; 84(11):2673-2677. PMID: 30032487.
    Citations: 4     Fields:    Translation:Humans
  52. Al-Samkari H, Kuter DJ. Relative potency of the thrombopoietin receptor agonists eltrombopag, avatrombopag and romiplostim in a patient with chronic immune thrombocytopenia. Br J Haematol. 2018 10; 183(2):168. PMID: 29978577.
    Citations: 4     Fields:    Translation:Humans
  53. Al-Samkari H, Grace RF, Connors JM. Ofatumumab for acute treatment and prophylaxis of a patient with multiple relapses of acquired thrombotic thrombocytopenic purpura. J Thromb Thrombolysis. 2018 Jul; 46(1):81-83. PMID: 29564686.
    Citations: 2     Fields:    Translation:Humans
  54. Al-Samkari H, Croteau SE. Shifting Landscape of Hemophilia Therapy: Implications for Current Clinical Laboratory Coagulation Assays. Am J Hematol. 2018 Jun 08. PMID: 29884997.
    Citations: 1     Fields:    
  55. Kritharis A, Al-Samkari H, Kuter DJ. Hereditary hemorrhagic telangiectasia: diagnosis and management from the hematologist's perspective. Haematologica. 2018 09; 103(9):1433-1443. PMID: 29794143.
    Citations: 11     Fields:    Translation:HumansAnimals
  56. Al-Samkari H, Marshall AL, Goodarzi K, Kuter DJ. Romiplostim for the management of perioperative thrombocytopenia. Br J Haematol. 2018 07; 182(1):106-113. PMID: 29767837.
    Citations: 6     Fields:    Translation:Humans
  57. Al-Samkari H, Connors JM. Dual anticoagulation with fondaparinux and dabigatran for treatment of cancer-associated hypercoagulability. Am J Hematol. 2018 06; 93(6):E156-E158. PMID: 29603336.
    Citations: 3     Fields:    Translation:Humans
  58. Al-Samkari H, Connors JM. Approach to Thrombophilia Testing in Patients with Splanchnic Vein Thrombosis. AME Med J. 2018; 3(7).
  59. Al-Samkari H, Marshall AL, Goodarzi K, Kuter DJ. The use of romiplostim in treating chemotherapy-induced thrombocytopenia in patients with solid tumors. Haematologica. 2018 04; 103(4):e169-e172. PMID: 29242295.
    Citations: 6     Fields:    Translation:Humans
  60. Al-Samkari H, Connors JM. Anticoagulation and Enzalutamide: Caution Over Convenience. J Oncol Pract. 2017 11; 13(11):728-729. PMID: 29125926.
    Citations:    Fields:    Translation:Humans
  61. Al-Samkari H, Berliner N. Hemophagocytic Lymphohistiocytosis. Annu Rev Pathol. 2018 01 24; 13:27-49. PMID: 28934563.
    Citations: 25     Fields:    Translation:Humans
  62. Phua PD, Al-Samkari HT, Borschel GH. Is the term "obstetrical brachial plexus palsy" obsolete? An international survey to assess consensus among peripheral nerve surgeons. J Plast Reconstr Aesthet Surg. 2012 Sep; 65(9):1227-32. PMID: 22512941.
    Citations: 1     Fields:    Translation:Humans
  63. Al-Samkari HT, Kane AA, Molter DW, Vachharajani A. Neonatal outcomes of Pierre Robin sequence: an institutional experience. Clin Pediatr (Phila). 2010 Dec; 49(12):1117-22. PMID: 20837617.
    Citations: 7     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.