Harvard Catalyst Profiles

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Seth M. Bloom, M.D., Ph.D.

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Biography
Washington University, St. Louis, MO, USABA05/2004Biology
Washington University School of Medicine, St. Louis, MO, USAMD, PhD05/2012Medicine and Microbiology
Barnes-Jewish Hospital & Washington University, St. Louis, MO, USA06/2015Internal Medicine (residency)
Massachusetts General Hospital and Brigham & Women's Hospital, Boston, MA, USA07/2017Infectious Diseases (fellowship)

Overview
I am an Infectious Disease physician-scientist at Massachusetts General Hospital and Instructor in Medicine at HMS doing research at the Ragon Institute of MGH, MIT, and Harvard. I study how the cervicovaginal microbiota and metabolome influence genital tract health, mucosal immunity, and risk for diseases such as HIV and bacterial vaginosis. I seek to elucidate basic mechanisms of disease and identify new therapies to modify microbiota composition. This research is broadly relevant for genital tract health but holds particular importance for southern and eastern African populations, where the burden of key microbiota-associated diseases is highest.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.