Harvard Catalyst Profiles

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Erik Henry Knelson, M.D.,Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F30CA168043 (KNELSON, ERIK H.) Apr 1, 2012 - Mar 31, 2014
    The Role of Stroma-derived Soluble TbetaRIII in Neuroblastoma
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gupta S, Dawood H, Giantini Larsen A, Fandino L, Knelson EH, Smith TR, Lee EQ, Aizer A, Dunn IF, Bi WL. Surgical and Peri-Operative Considerations for Brain Metastases. Front Oncol. 2021; 11:662943. PMID: 34026641.
  2. Tani T, Kitajima S, Conway EB, Knelson EH, Barbie DA. KRAS G12C inhibition and innate immune targeting. Expert Opin Ther Targets. 2021 Mar; 25(3):167-174. PMID: 33703985.
    Citations:    Fields:    
  3. Mahadevan NR, Knelson EH, Wolff JO, Vajdi A, Saigi M, Campisi M, Hong D, Thai TC, Piel B, Han S, Reinhold BB, Duke-Cohan JS, Poitras MJ, Taus LJ, Lizotte PH, Portell A, Quadros V, Santucci AD, Murayama T, Canadas I, Kitajima S, Akitsu A, Fridrikh M, Watanabe H, Reardon B, Gokhale PC, Paweletz CP, Awad MM, Van Allen EM, Lako A, Wang XT, Chen B, Hong F, Sholl LM, Tolstorukov MY, Pfaff K, Janne PA, Gjini E, Edwards R, Rodig S, Reinherz EL, Oser MG, Barbie DA. Intrinsic immunogenicity of small cell lung carcinoma revealed by its cellular plasticity. Cancer Discov. 2021 Mar 11. PMID: 33707236.
    Citations:    Fields:    
  4. Knelson EH, Patel SA, Sands JM. PARP Inhibitors in Small-Cell Lung Cancer: Rational Combinations to Improve Responses. Cancers (Basel). 2021 Feb 10; 13(4). PMID: 33578789.
    Citations: 1     
  5. Campisi M, Sundararaman SK, Shelton SE, Knelson EH, Mahadevan NR, Yoshida R, Tani T, Ivanova E, Cañadas I, Osaki T, Lee SWL, Thai T, Han S, Piel BP, Gilhooley S, Paweletz CP, Chiono V, Kamm RD, Kitajima S, Barbie DA. Tumor-Derived cGAMP Regulates Activation of the Vasculature. Front Immunol. 2020; 11:2090. PMID: 33013881.
    Citations: 3     Fields:    Translation:HumansCells
  6. Puram RV, Erdil RM, Weber BN, Knelson EH, Van Beuningen AM, Wallwork R, Gilyard SN, Curtis BR, Ranganathan R, Leaf RK, Malhotra R. Thrombocytopenia and Thromboses in Myocardial Infarction Associated with Eptifibatide-Dependent Activating Antiplatelet Antibodies. Thromb Haemost. 2020 Jul; 120(7):1137-1141. PMID: 32483771.
    Citations:    Fields:    
  7. Kurppa KJ, Liu Y, To C, Zhang T, Fan M, Vajdi A, Knelson EH, Xie Y, Lim K, Cejas P, Portell A, Lizotte PH, Ficarro SB, Li S, Chen T, Haikala HM, Wang H, Bahcall M, Gao Y, Shalhout S, Boettcher S, Shin BH, Thai T, Wilkens MK, Tillgren ML, Mushajiang M, Xu M, Choi J, Bertram AA, Ebert BL, Beroukhim R, Bandopadhayay P, Awad MM, Gokhale PC, Kirschmeier PT, Marto JA, Camargo FD, Haq R, Paweletz CP, Wong KK, Barbie DA, Long HW, Gray NS, Jänne PA. Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. Cancer Cell. 2020 01 13; 37(1):104-122.e12. PMID: 31935369.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  8. Ritter JL, Zhu Z, Thai TC, Mahadevan NR, Mertins P, Knelson EH, Piel BP, Han S, Jaffe JD, Carr SA, Barbie DA, Barbie TU. Phosphorylation of RAB7 by TBK1/IKKe Regulates Innate Immune Signaling in Triple-Negative Breast Cancer. Cancer Res. 2020 01 01; 80(1):44-56. PMID: 31662325.
    Citations: 3     Fields:    Translation:HumansCells
  9. Knelson EH, Vaidya A, Rawizza HE, Vaduganathan M, O'Gara PT. On the Cusp. N Engl J Med. 2017 05 25; 376(21):e45. PMID: 28538122.
    Citations:    Fields:    Translation:HumansCells
  10. Gaviglio AL, Knelson EH, Blobe GC. Heparin-binding epidermal growth factor-like growth factor promotes neuroblastoma differentiation. FASEB J. 2017 05; 31(5):1903-1915. PMID: 28174207.
    Citations: 7     Fields:    Translation:HumansCells
  11. Knelson EH, Gaviglio AL, Nee JC, Starr MD, Nixon AB, Marcus SG, Blobe GC. Stromal heparan sulfate differentiates neuroblasts to suppress neuroblastoma growth. J Clin Invest. 2014 Jul; 124(7):3016-31. PMID: 24937430.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  12. Knelson EH, Nee JC, Blobe GC. Heparan sulfate signaling in cancer. Trends Biochem Sci. 2014 Jun; 39(6):277-88. PMID: 24755488.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  13. Knelson EH, Gaviglio AL, Tewari AK, Armstrong MB, Mythreye K, Blobe GC. Type III TGF-ß receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma. J Clin Invest. 2013 Nov; 123(11):4786-98. PMID: 24216509.
    Citations: 16     Fields:    Translation:HumansCells
  14. Oh SY, Knelson EH, Blobe GC, Mythreye K. The type III TGFß receptor regulates filopodia formation via a Cdc42-mediated IRSp53-N-WASP interaction in epithelial cells. Biochem J. 2013 Aug 15; 454(1):79-89. PMID: 23750457.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  15. Van Mater D, Knelson EH, Kaiser-Rogers KA, Armstrong MB. Neuroblastoma in a pediatric patient with a microduplication of 2p involving the MYCN locus. . 2013 Mar; 161A(3):605-10. PMID: 23401364.
    Citations: 3     Translation:HumansCells
  16. Mythreye K, Knelson EH, Gatza CE, Gatza ML, Blobe GC. TßRIII/ß-arrestin2 regulates integrin a5ß1 trafficking, function, and localization in epithelial cells. Oncogene. 2013 Mar 14; 32(11):1416-27. PMID: 22562249.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  17. Ramirez JJ, Poulton WE, Knelson E, Barton C, King MA, Klein RL. Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory. Behav Brain Res. 2011 Jan 01; 216(1):332-40. PMID: 20727915.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.