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Martin S. Taylor, M.D.,Ph.D.

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Research
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  1. K08DK129824 (TAYLOR, MARTIN S) Jul 15, 2021 - Apr 30, 2026
    NIH
    Elucidating structural, mechanistic, and allosteric determinants of mTOR Complex 2 (mTORC2) signaling.
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Rajurkar M, Parikh AR, Solovyov A, You E, Kulkarni AS, Chu C, Xu KH, Jaicks C, Taylor MS, Wu C, Alexander KA, Good CR, Szabolcs A, Gerstberger S, Tran AV, Xu N, Ebright RY, Van Seventer EE, Vo KD, Tai EC, Lu C, Joseph-Chazan J, Raabe MJ, Nieman LT, Desai N, Arora KS, Ligorio M, Thapar V, Cohen L, Garden PM, Senussi Y, Zheng H, Allen JN, Blaszkowsky LS, Clark JW, Goyal L, Wo JY, Ryan DP, Corcoran RB, Deshpande V, Rivera MN, Aryee MJ, Hong TS, Berger SL, Walt DR, Burns KH, Park PJ, Greenbaum BD, Ting DT. Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer. Cancer Discov. 2022 06 02; 12(6):1462-1481. PMID: 35320348; PMCID: PMC9167735.
    Citations:    Fields:    Translation:HumansAnimals
  2. Rickelt S, Neyaz A, Condon C, Whittaker CA, Zaidi AH, Taylor MS, Abbruzzese G, Mattia AR, Zukerberg L, Shroff SG, Yilmaz OH, Yilmaz O, Wu EY, Choi WT, Jobe BA, Odze RD, Patil DT, Deshpande V, Hynes RO. Agrin Loss in Barrett's Esophagus-Related Neoplasia and Its Utility as a Diagnostic and Predictive Biomarker. Clin Cancer Res. 2022 03 15; 28(6):1167-1179. PMID: 34785582; PMCID: PMC8923984.
    Citations:    Fields:    Translation:Humans
  3. Chebib I, Taylor MS, Nardi V, Rivera MN, Lennerz JK, Cote GM, Choy E, Lozano Calderón SA, Raskin KA, Schwab JH, Mullen JT, Chen YE, Hung YP, Nielsen GP, Deshpande V. Clinical Utility of Anchored Multiplex Solid Fusion Assay for Diagnosis of Bone and Soft Tissue Tumors. Am J Surg Pathol. 2021 08 01; 45(8):1127-1137. PMID: 34115673.
    Citations:    Fields:    Translation:Humans
  4. Ukadike KC, Ni K, Wang X, Taylor MS, LaCava J, Pachman LM, Eckert M, Stevens A, Lood C, Mustelin T. IgG and IgA autoantibodies against L1 ORF1p expressed in granulocytes correlate with granulocyte consumption and disease activity in pediatric systemic lupus erythematosus. Arthritis Res Ther. 2021 05 29; 23(1):153. PMID: 34051843; PMCID: PMC8164314.
    Citations:    Fields:    Translation:HumansCells
  5. Pereira B, Chen CT, Goyal L, Walmsley C, Pinto CJ, Baiev I, Allen R, Henderson L, Saha S, Reyes S, Taylor MS, Fitzgerald DM, Broudo MW, Sahu A, Gao X, Winckler W, Brannon AR, Engelman JA, Leary R, Stone JR, Campbell CD, Juric D. Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer. Nat Commun. 2021 05 27; 12(1):3199. PMID: 34045463.
    Citations: 7     Fields:    Translation:Humans
  6. Miller JO, Shih AR, Mino-Kenudson M, Taylor MS, Goldman JL. Trimethoprim-Sulfamethoxazole-associated Fulminant Respiratory Failure in Children and Young Adults. Am J Respir Crit Care Med. 2021 04 01; 203(7):918-921. PMID: 33513317; PMCID: PMC8017575.
    Citations: 1     Fields:    Translation:Humans
  7. Hung YP, Chen AL, Taylor MS, Huynh TG, Kem M, Selig MK, Nielsen GP, Lennerz JK, Azzoli CG, Dagogo-Jack I, Kradin RL, Mino-Kenudson M. Thoracic nuclear protein in testis (NUT) carcinoma: expanded pathological spectrum with expression of thyroid transcription factor-1 and neuroendocrine markers. Histopathology. 2021 May; 78(6):896-904. PMID: 33231320.
    Citations: 5     Fields:    Translation:Humans
  8. Anderson MA, Dhami RS, Fadzen CM, Molina G, Taylor MS, Deshpande V, Qadan M, Catalano OA, Ferrone CR, Mojtahed A. CT and MRI features differentiating mucinous cystic neoplasms of the liver from pathologically simple cysts. Clin Imaging. 2021 Aug; 76:46-52. PMID: 33549919.
    Citations: 2     Fields:    Translation:Humans
  9. Michelakos T, Cai L, Villani V, Sabbatino F, Kontos F, Fernández-Del Castillo C, Yamada T, Neyaz A, Taylor MS, Deshpande V, Kurokawa T, Ting DT, Qadan M, Weekes CD, Allen JN, Clark JW, Hong TS, Ryan DP, Wo JY, Warshaw AL, Lillemoe KD, Ferrone S, Ferrone CR. Tumor Microenvironment Immune Response in Pancreatic Ductal Adenocarcinoma Patients Treated With Neoadjuvant Therapy. J Natl Cancer Inst. 2021 02 01; 113(2):182-191. PMID: 32497200; PMCID: PMC7850539.
    Citations: 11     Fields:    Translation:Humans
  10. Miller PG, Sperling AS, Gibson CJ, Viswanathan K, Castellano C, McConkey M, Ceremsak J, Taylor MS, Birndt S, Perner F, Arnason J, Agrawal M, Schram AM, Nikiforow S, Pihan G, Hasserjian RP, Aster JC, La Rosée P, Morgan EA, Berliner N, Ebert BL. Contribution of clonal hematopoiesis to adult-onset hemophagocytic lymphohistiocytosis. Blood. 2020 12 24; 136(26):3051-3055. PMID: 32961550; PMCID: PMC7770567.
    Citations: 6     Fields:    Translation:HumansAnimals
  11. Neyaz A, Odze RD, Rickelt S, Nieman LT, Bledsoe JR, Mahadevan KK, Arora K, Jeck WR, Taylor MS, Gala M, Patil DT, Yilmaz OH, Rivera MN, Ting DT, Deshpande V. LGR5 in Barrett's Esophagus and its Utility in Predicting Patients at Increased Risk of Advanced Neoplasia. Clin Transl Gastroenterol. 2020 12 22; 12(1):e00272. PMID: 33464729.
    Citations:    Fields:    Translation:Humans
  12. Honselmann KC, Pergolini I, Castillo CF, Deshpande V, Ting D, Taylor MS, Bolm L, Qadan M, Wellner U, Sandini M, Bausch D, Warshaw AL, Lillemoe KD, Keck T, Ferrone CR. Timing But Not Patterns of Recurrence Is Different Between Node-negative and Node-positive Resected Pancreatic Cancer. Ann Surg. 2020 08; 272(2):357-365. PMID: 32675550; PMCID: PMC6639153.
    Citations: 13     Fields:    Translation:Humans
  13. Erstad DJ, Sojoodi M, Taylor MS, Jordan VC, Farrar CT, Axtell AL, Rotile NJ, Jones C, Graham-O'Regan KA, Ferreira DS, Michelakos T, Kontos F, Chawla A, Li S, Ghoshal S, Chen YI, Arora G, Humblet V, Deshpande V, Qadan M, Bardeesy N, Ferrone CR, Lanuti M, Tanabe KK, Caravan P, Fuchs BC. Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and Is Measurable with Collagen-Targeted Molecular MRI. Clin Cancer Res. 2020 09 15; 26(18):5007-5018. PMID: 32611647.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  14. Neyaz A, Tabb ES, Shih A, Zhao Q, Shroff S, Taylor MS, Rickelt S, Wo JY, Fernandez-Del Castillo C, Qadan M, Hong TS, Lillemoe KD, Ting DT, Ferrone CR, Deshpande V. Pancreatic ductal adenocarcinoma: tumour regression grading following neoadjuvant FOLFIRINOX and radiation. Histopathology. 2020 Jul; 77(1):35-45. PMID: 32031712.
    Citations: 2     Fields:    Translation:Humans
  15. Reiter JG, Hung WT, Lee IH, Nagpal S, Giunta P, Degner S, Liu G, Wassenaar ECE, Jeck WR, Taylor MS, Farahani AA, Marble HD, Knott S, Kranenburg O, Lennerz JK, Naxerova K. Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases. Nat Genet. 2020 07; 52(7):692-700. PMID: 32451459.
    Citations: 26     Fields:    Translation:Humans
  16. Erstad DJ, Taylor MS, Qadan M, Axtell AL, Fuchs BC, Berger DL, Clancy TE, Tanabe KK, Chang DC, Ferrone CR. Platelet and neutrophil to lymphocyte ratios predict survival in patients with resectable colorectal liver metastases. Am J Surg. 2020 12; 220(6):1579-1585. PMID: 32580870.
    Citations: 2     Fields:    Translation:HumansCells
  17. Liang NE, Taylor MS, Ferrone CR. A Rare Case of Gallbladder Small Cell Carcinoma. J Gastrointest Surg. 2021 02; 25(2):561-564. PMID: 32394121.
    Citations:    Fields:    Translation:Humans
  18. Crotty R, Taylor MS, Farmer JR, Kakar S, Yilmaz F, Ardeniz Ö, Patil DT, Deshpande V. Spectrum of Hepatic Manifestations of Common Variable Immunodeficiency. Am J Surg Pathol. 2020 05; 44(5):617-625. PMID: 32187043.
    Citations: 3     Fields:    Translation:HumansCells
  19. Miller PG, Niroula A, Ceremsak JJ, Gibson CJ, Taylor MS, Birndt S, Perner F, Arnason J, Sperling AS, Agrawal M, Schram AM, Nikiforow S, Pihan G, Hasserjian RP, Aster JC, La Rosée P, Morgan EA, Berliner N, Ebert BL. Identification of germline variants in adults with hemophagocytic lymphohistiocytosis. Blood Adv. 2020 03 10; 4(5):925-929. PMID: 32150605.
    Citations: 3     Fields:    Translation:HumansCells
  20. Ardeljan D, Steranka JP, Liu C, Li Z, Taylor MS, Payer LM, Gorbounov M, Sarnecki JS, Deshpande V, Hruban RH, Boeke JD, Fenyö D, Wu PH, Smogorzewska A, Holland AJ, Burns KH. Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication. Nat Struct Mol Biol. 2020 02; 27(2):168-178. PMID: 32042151; PMCID: PMC7080318.
    Citations: 24     Fields:    Translation:HumansCells
  21. Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM. Author Correction: A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nat Med. 2020 Feb; 26(2):300. PMID: 31996837; PMCID: PMC7545464.
    Citations: 2     Fields:    
  22. Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM. A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nat Med. 2020 02; 26(2):244-251. PMID: 31959991; PMCID: PMC7018620.
    Citations: 15     Fields:    Translation:HumansCells
  23. Carter V, LaCava J, Taylor MS, Liang SY, Mustelin C, Ukadike KC, Bengtsson A, Lood C, Mustelin T. High Prevalence and Disease Correlation of Autoantibodies Against p40 Encoded by Long Interspersed Nuclear Elements in Systemic Lupus Erythematosus. Arthritis Rheumatol. 2020 01; 72(1):89-99. PMID: 31342656; PMCID: PMC6935427.
    Citations: 11     Fields:    Translation:HumansCells
  24. Mustelin T, Ukadike K, LaCava J, Taylor M. Reply. Arthritis Rheumatol. 2020 02; 72(2):376-377. PMID: 31513363.
    Citations:    Fields:    Translation:HumansCells
  25. Zubiri L, Allen IM, Taylor MS, Guidon AC, Chen ST, Schoenfeld SR, Neilan TG, Sise ME, Mooradian MJ, Rubin KM, Leaf RK, Parikh AR, Faje A, Gainor JF, Cohen JV, Fintelmann FJ, Kohler MJ, Dougan M, Reynolds KL. Immune-Related Adverse Events in the Setting of PD-1/L1 Inhibitor Combination Therapy. Oncologist. 2020 03; 25(3):e398-e404. PMID: 32162817; PMCID: PMC7066708.
    Citations: 3     Fields:    Translation:Humans
  26. Zubiri L, Allen IM, Taylor MS, Guidon AC, Chen ST, Schoenfeld SR, Neilan TG, Sise ME, Mooradian MJ, Rubin KM, Leaf RK, Parikh AR, Faje A, Gainor JF, Cohen JV, Fintelmann FJ, Kohler MJ, Dougan M, Reynolds KL. Immune-Related Adverse Events in the Setting of PD-1/L1 Inhibitor Combination Therapy. Oncologist. 2019 Nov 21. PMID: 31754069.
    Citations:    
  27. Leijssen LGJ, Dinaux AM, Taylor MS, Deshpande V, Kunitake H, Bordeianou LG, Berger DL. Perineural Invasion Is a Prognostic but not a Predictive Factor in Nonmetastatic Colon Cancer. Dis Colon Rectum. 2019 10; 62(10):1212-1221. PMID: 31490830.
    Citations: 10     Fields:    Translation:Humans
  28. Krystel-Whittemore M, Taylor MS, Rivera M, Lennerz JK, Le LP, Dias-Santagata D, Iafrate AJ, Deshpande V, Chebib I, Nielsen GP, Wu CL, Nardi V. Novel and established EWSR1 gene fusions and associations identified by next-generation sequencing and fluorescence in-situ hybridization. Hum Pathol. 2019 11; 93:65-73. PMID: 31430493.
    Citations: 9     Fields:    Translation:Humans
  29. Diaz-Perez JA, Nielsen GP, Antonescu C, Taylor MS, Lozano-Calderon SA, Rosenberg AE. EWSR1/FUS-NFATc2 rearranged round cell sarcoma: clinicopathological series of 4 cases and literature review. Hum Pathol. 2019 08; 90:45-53. PMID: 31078563; PMCID: PMC6714048.
    Citations: 10     Fields:    Translation:Humans
  30. Jiang H, Taylor MS, Molloy KR, Altukhov I, LaCava J. Identification of RNase-sensitive LINE-1 Ribonucleoprotein Interactions by Differential Affinity Immobilization. Bio Protoc. 2019 Apr 05; 9(7). PMID: 31106238; PMCID: PMC6519465.
    Citations: 1     
  31. Taylor MS, Chougule A, MacLeay AR, Kurzawa P, Chebib I, Le L, Deshpande V. Morphologic Overlap Between Inflammatory Myofibroblastic Tumor and IgG4-related Disease: Lessons From Next-generation Sequencing. Am J Surg Pathol. 2019 03; 43(3):314-324. PMID: 30451733; PMCID: PMC6637760.
    Citations: 9     Fields:    Translation:Humans
  32. Suster DI, Deshpande V, Chebib I, Taylor MS, Mullen J, Bredella MA, Nielsen GP. Spindle cell liposarcoma with a TRIO-TERT fusion transcript. Virchows Arch. 2019 Sep; 475(3):391-394. PMID: 30793229.
    Citations: 2     Fields:    Translation:Humans
  33. Chougule A, Taylor MS, Nardi V, Chebib I, Cote GM, Choy E, Nielsen GP, Deshpande V. Spindle and Round Cell Sarcoma With EWSR1-PATZ1 Gene Fusion: A Sarcoma With Polyphenotypic Differentiation. Am J Surg Pathol. 2019 02; 43(2):220-228. PMID: 30379650; PMCID: PMC6590674.
    Citations: 15     Fields:    Translation:Humans
  34. Cai L, Michelakos T, Deshpande V, Arora KS, Yamada T, Ting DT, Taylor MS, Castillo CF, Warshaw AL, Lillemoe KD, Ferrone S, Ferrone CR. Role of Tumor-Associated Macrophages in the Clinical Course of Pancreatic Neuroendocrine Tumors (PanNETs). Clin Cancer Res. 2019 04 15; 25(8):2644-2655. PMID: 30670493; PMCID: PMC6582654.
    Citations: 24     Fields:    Translation:HumansCells
  35. Honselmann KC, Pergolini I, Castillo CF, Deshpande V, Ting D, Taylor MS, Bolm L, Qadan M, Wellner U, Sandini M, Bausch D, Warshaw AL, Lillemoe KD, Keck T, Ferrone CR. Timing But Not Patterns of Recurrence Is Different Between Node-negative and Node-positive Resected Pancreatic Cancer. Ann Surg. 2019 Jan 18. PMID: 30672796.
    Citations:    Fields:    
  36. Leijssen LGJ, Dinaux AM, Amri R, Taylor MS, Deshpande V, Bordeianou LG, Kunitake H, Berger DL. Impact of intramural and extramural vascular invasion on stage II-III colon cancer outcomes. J Surg Oncol. 2019 May; 119(6):749-757. PMID: 30644557; PMCID: PMC6629581.
    Citations: 11     Fields:    Translation:Humans
  37. Erstad DJ, Sojoodi M, Taylor MS, Ghoshal S, Razavi AA, Graham-O'Regan KA, Bardeesy N, Ferrone CR, Lanuti M, Caravan P, Tanabe KK, Fuchs BC. Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy. Dis Model Mech. 2018 07 30; 11(7). PMID: 29903803.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  38. Farago AF, Taylor MS, Doebele RC, Zhu VW, Kummar S, Spira AI, Boyle TA, Haura EB, Arcila ME, Benayed R, Aisner DL, Horick NK, Lennerz JK, Le LP, Iafrate AJ, Ou SI, Shaw AT, Mino-Kenudson M, Drilon A. Clinicopathologic Features of Non-Small-Cell Lung Cancer Harboring an NTRK Gene Fusion. JCO Precis Oncol. 2018; 2018. PMID: 30215037; PMCID: PMC6132056.
    Citations: 44     Fields:    
  39. Taylor MS, Chivukula RR, Myers LC, Jeck WR, Waghray A, Tata PR, Selig MK, O'Donnell WJ, Farver CF, Thompson BT, Rajagopal J, Kradin RL. A Conserved Distal Lung Regenerative Pathway in Acute Lung Injury. Am J Pathol. 2018 05; 188(5):1149-1160. PMID: 29476724; PMCID: PMC5906746.
    Citations: 11     Fields:    Translation:Humans
  40. Taylor MS, Chivukula RR, Myers LC, Jeck WR, Tata PR, O'Donnell WJ, Farver CF, Thompson BT, Rajagopal J, Kradin RL. Delayed Alveolar Epithelialization: A Distinct Pathology in Diffuse Acute Lung Injury. Am J Respir Crit Care Med. 2018 02 15; 197(4):522-524. PMID: 28696778; PMCID: PMC5821904.
    Citations: 3     Fields:    Translation:Humans
  41. Zhang Y, Poobalasingam T, Yates LL, Walker SA, Taylor MS, Chessum L, Harrison J, Tsaprouni L, Adcock IM, Lloyd CM, Cookson WO, Moffatt MF, Dean CH. Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma. Dis Model Mech. 2018 01 29; 11(1). PMID: 29361513; PMCID: PMC5818078.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  42. Taylor MS, Altukhov I, Molloy KR, Mita P, Jiang H, Adney EM, Wudzinska A, Badri S, Ischenko D, Eng G, Burns KH, Fenyö D, Chait BT, Alexeev D, Rout MP, Boeke JD, LaCava J. Dissection of affinity captured LINE-1 macromolecular complexes. Elife. 2018 01 08; 7. PMID: 29309035.
    Citations: 29     Fields:    Translation:HumansCells
  43. Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol. 2017 12 08; 35(12):1211. PMID: 29220013.
    Citations:    Fields:    
  44. Miller CL, Taylor MS, Qadan M, Deshpande V, Worthington S, Smalley R, Collura C, Ryan DP, Allen JN, Blaszkowsky LS, Clark JW, Murphy JE, Parikh AR, Berger D, Tanabe KK, Lillemoe KD, Ferrone CR. Prognostic Significance of Surgical Margin Size After Neoadjuvant FOLFOX and/or FOLFIRI for Colorectal Liver Metastases. J Gastrointest Surg. 2017 Nov; 21(11):1831-1840. PMID: 28884391.
    Citations: 8     Fields:    Translation:Humans
  45. Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera FJ, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol. 2017 06; 35(6):569-576. PMID: 28459449; PMCID: PMC5462879.
    Citations: 111     Fields:    Translation:AnimalsCells
  46. Ardeljan D, Taylor MS, Ting DT, Burns KH. The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia. Clin Chem. 2017 04; 63(4):816-822. PMID: 28188229; PMCID: PMC6177209.
    Citations: 39     Fields:    Translation:HumansCells
  47. Ardeljan D, Taylor MS, Burns KH, Boeke JD, Espey MG, Woodhouse EC, Howcroft TK. Meeting Report: The Role of the Mobilome in Cancer. Cancer Res. 2016 08 01; 76(15):4316-9. PMID: 27527733; PMCID: PMC4991632.
    Citations: 3     Fields:    Translation:HumansCells
  48. Taylor MS, LaCava J, Dai L, Mita P, Burns KH, Rout MP, Boeke JD. Characterization of L1-Ribonucleoprotein Particles. Methods Mol Biol. 2016; 1400:311-38. PMID: 26895062; PMCID: PMC5084692.
    Citations: 12     Fields:    Translation:HumansCells
  49. Sharma R, Rodic N, Burns KH, Taylor MS. Immunodetection of Human LINE-1 Expression in Cultured Cells and Human Tissues. Methods Mol Biol. 2016; 1400:261-80. PMID: 26895059; PMCID: PMC5679191.
    Citations: 8     Fields:    Translation:HumansCells
  50. Rodic N, Steranka JP, Makohon-Moore A, Moyer A, Shen P, Sharma R, Kohutek ZA, Huang CR, Ahn D, Mita P, Taylor MS, Barker NJ, Hruban RH, Iacobuzio-Donahue CA, Boeke JD, Burns KH. Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma. Nat Med. 2015 Sep; 21(9):1060-4. PMID: 26259033; PMCID: PMC4775273.
    Citations: 68     Fields:    Translation:HumansCells
  51. Kaiser VB, Svinti V, Prendergast JG, Chau YY, Campbell A, Patarcic I, Barroso I, Joshi PK, Hastie ND, Miljkovic A, Taylor MS, Enroth S, Memari Y, Kolb-Kokocinski A, Wright AF, Gyllensten U, Durbin R, Rudan I, Campbell H, Polašek O, Johansson Å, Sauer S, Porteous DJ, Fraser RM, Drake C, Vitart V, Hayward C, Semple CA, Wilson JF. Homozygous loss-of-function variants in European cosmopolitan and isolate populations. Hum Mol Genet. 2015 Oct 01; 24(19):5464-74. PMID: 26173456; PMCID: PMC4572071.
    Citations: 15     Fields:    Translation:Humans
  52. Taylor MS, Dempsey DR, Hwang Y, Chen Z, Chu N, Boeke JD, Cole PA. Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs. Bioorg Chem. 2015 Oct; 62:64-73. PMID: 26246082; PMCID: PMC4567917.
    Citations: 5     Fields:    Translation:AnimalsCells
  53. Luciano M, Svinti V, Campbell A, Marioni RE, Hayward C, Wright AF, Taylor MS, Porteous DJ, Thomson P, Prendergast JG, Hastie ND, Farrington SM, Scotland G, Dunlop MG, Deary IJ. Exome sequencing to detect rare variants associated with general cognitive ability: a pilot study. Twin Res Hum Genet. 2015 Apr; 18(2):117-25. PMID: 25744449.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  54. LaCava J, Molloy KR, Taylor MS, Domanski M, Chait BT, Rout MP. Affinity proteomics to study endogenous protein complexes: pointers, pitfalls, preferences and perspectives. Biotechniques. 2015 Mar; 58(3):103-19. PMID: 25757543.
    Citations: 23     Fields:    Translation:HumansCells
  55. Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, Rainger JK, Karaca E, Gonzaga-Jauregui C, Jhangiani S, Muzny DM, Seawright A, Soares DC, Kharbanda M, Murday V, Finch A, Gibbs RA, van Heyningen V, Taylor MS, Yakut T, Knappskog PM, Hurles ME, Ponting CP, Lupski JR, Houge G, FitzPatrick DR. Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations. Am J Hum Genet. 2014 Jun 05; 94(6):915-23. PMID: 24906020; PMCID: PMC4121478.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  56. Dai L, LaCava J, Taylor MS, Boeke JD. Expression and detection of LINE-1 ORF-encoded proteins. Mob Genet Elements. 2014; 4:e29319. PMID: 25054082.
    Citations: 20     
  57. Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA, Taverna SD, Qian J, Tackett AJ, Ratan RR, McDonald OG, Feinberg AP, Cole PA. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20; 9(6):1284-93. PMID: 24707965.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  58. Rodic N, Sharma R, Sharma R, Zampella J, Dai L, Taylor MS, Hruban RH, Iacobuzio-Donahue CA, Maitra A, Torbenson MS, Goggins M, Shih IeM, Duffield AS, Montgomery EA, Gabrielson E, Netto GJ, Lotan TL, De Marzo AM, Westra W, Binder ZA, Orr BA, Gallia GL, Eberhart CG, Boeke JD, Harris CR, Burns KH. Long interspersed element-1 protein expression is a hallmark of many human cancers. Am J Pathol. 2014 May; 184(5):1280-6. PMID: 24607009; PMCID: PMC4005969.
    Citations: 112     Fields:    Translation:HumansCells
  59. Williamson KA, Rainger J, Floyd JA, Ansari M, Meynert A, Aldridge KV, Rainger JK, Anderson CA, Moore AT, Hurles ME, Clarke A, van Heyningen V, Verloes A, Taylor MS, Wilkie AO, Fitzpatrick DR. Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects. Am J Hum Genet. 2014 Feb 06; 94(2):295-302. PMID: 24462371; PMCID: PMC3928658.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  60. Taylor MS, LaCava J, Mita P, Molloy KR, Huang CR, Li D, Adney EM, Jiang H, Burns KH, Chait BT, Rout MP, Boeke JD, Dai L. Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition. Cell. 2013 Nov 21; 155(5):1034-48. PMID: 24267889.
    Citations: 102     Fields:    Translation:HumansAnimalsCells
  61. Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, Huang CRL, Berndsen CE, Kim MS, Pandey A, Wolberger C, Marmorstein R, Machamer C, Boeke JD, Cole PA. Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase. J Biol Chem. 2013 Nov 08; 288(45):32211-32228. PMID: 24045953.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  62. Meynert AM, Bicknell LS, Hurles ME, Jackson AP, Taylor MS. Quantifying single nucleotide variant detection sensitivity in exome sequencing. BMC Bioinformatics. 2013 Jun 18; 14:195. PMID: 23773188; PMCID: PMC3695811.
    Citations: 32     Fields:    Translation:Humans
  63. Dai L, Taylor MS, O'Donnell KA, Boeke JD. Poly(A) binding protein C1 is essential for efficient L1 retrotransposition and affects L1 RNP formation. Mol Cell Biol. 2012 Nov; 32(21):4323-36. PMID: 22907758.
    Citations: 35     Fields:    Translation:HumansCells
  64. Devonshire AS, Sanders R, Wilkes TM, Taylor MS, Foy CA, Huggett JF. Application of next generation qPCR and sequencing platforms to mRNA biomarker analysis. Methods. 2013 Jan; 59(1):89-100. PMID: 22841564.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  65. Taylor MS, Hwang Y, Hsiao PY, Boeke JD, Cole PA. Ghrelin O-acyltransferase assays and inhibition. Methods Enzymol. 2012; 514:205-28. PMID: 22975055.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  66. Barnett BP, Hwang Y, Taylor MS, Kirchner H, Pfluger PT, Bernard V, Lin YY, Bowers EM, Mukherjee C, Song WJ, Longo PA, Leahy DJ, Hussain MA, Tschöp MH, Boeke JD, Cole PA. Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor. Science. 2010 Dec 17; 330(6011):1689-92. PMID: 21097901.
    Citations: 96     Fields:    Translation:HumansAnimalsCells
  67. Dickinson P, Smith SN, Webb S, Kilanowski FM, Campbell IJ, Taylor MS, Porteous DJ, Willemsen R, de Jonge HR, Farley R, Alton EW, Dorin JR. The severe G480C cystic fibrosis mutation, when replicated in the mouse, demonstrates mistrafficking, normal survival and organ-specific bioelectrics. Hum Mol Genet. 2002 Feb 01; 11(3):243-51. PMID: 11823443.
    Citations: 12     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.