Harvard Catalyst Profiles

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Gareth Rhys Willis, Ph.D.

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  1. 1K99HL146986-01A1 (Willis, Gareth Rhys) Feb 10, 2020 - Feb 1, 2025
    Mechanisms of immunomodulation in lung injury by mesenchymal stromal cell exosomes
    Role: PI

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mansouri N, Willis GR, Fernandez-Gonzalez A, Reis M, Nassiri S, Mitsialis SA, Kourembanas S. Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes. JCI Insight. 2019 Nov 01; 4(21). PMID: 31581150.
  2. Hudalla H, Michael Z, Christodoulou N, Willis GR, Fernandez-Gonzalez A, Filatava EJ, Dieffenbach P, Fredenburgh LE, Stearman RS, Geraci MW, Kourembanas S, Christou H. Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2019 10; 61(4):512-524. PMID: 30951642.
  3. Willis GR, Fernandez-Gonzalez A, Reis M, Mitsialis SA, Kourembanas S. Macrophage Immunomodulation: The Gatekeeper for Mesenchymal Stem Cell Derived-Exosomes in Pulmonary Arterial Hypertension? Int J Mol Sci. 2018 Aug 27; 19(9). PMID: 30150544.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Mitsialis SA, Willis GR, Fernandez-Gonzalez A, Kourembanas S. Reply to Muraca et al.: Exosome Treatment of Bronchopulmonary Dysplasia: How Pure Should Your Exosome Preparation Be? Am J Respir Crit Care Med. 2018 04 01; 197(7):970. PMID: 29160730.
    Citations: 1     Fields:    
  5. Willis GR, Fernandez-Gonzalez A, Anastas J, Vitali SH, Liu X, Ericsson M, Kwong A, Mitsialis SA, Kourembanas S. Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation. Am J Respir Crit Care Med. 2018 01 01; 197(1):104-116. PMID: 28853608.
    Citations: 16     Fields:    
  6. Willis GR, Mitsialis SA, Kourembanas S. "Good things come in small packages": application of exosome-based therapeutics in neonatal lung injury. Pediatr Res. 2018 01; 83(1-2):298-307. PMID: 28985201.
    Citations: 1     Fields:    
  7. Willis GR, Kourembanas S, Mitsialis SA. Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency. Front Cardiovasc Med. 2017; 4:63. PMID: 29062835.
    Citations: 8     
  8. Willis GR, Kourembanas S, Mitsialis SA. Therapeutic Applications of Extracellular Vesicles: Perspectives from Newborn Medicine. Methods Mol Biol. 2017; 1660:409-432. PMID: 28828676.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  9. Burnley-Hall N, Willis G, Davis J, Rees DA, James PE. Nitrite-derived nitric oxide reduces hypoxia-inducible factor 1a-mediated extracellular vesicle production by endothelial cells. Nitric Oxide. 2017 Feb 28; 63:1-12. PMID: 28017872.
    Citations: 3     Fields:    Translation:HumansCells
  10. James PE, Willis GR, Allen JD, Winyard PG, Jones AM. Nitrate pharmacokinetics: Taking note of the difference. Nitric Oxide. 2015 Aug 01; 48:44-50. PMID: 25937621.
    Citations: 1     Fields:    Translation:HumansAnimals
  11. Willis GR, Connolly K, Ladell K, Davies TS, Guschina IA, Ramji D, Miners K, Price DA, Clayton A, James PE, Rees DA. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Hum Reprod. 2014 Dec; 29(12):2756-63. PMID: 25336711.
    Citations: 3     Fields:    Translation:HumansCells
  12. Muggeridge DJ, Sculthorpe N, Grace FM, Willis G, Thornhill L, Weller RB, James PE, Easton C. Acute whole body UVA irradiation combined with nitrate ingestion enhances time trial performance in trained cyclists. Nitric Oxide. 2015 Aug 01; 48:3-9. PMID: 25289793.
    Citations: 3     Fields:    Translation:Humans
  13. Connolly KD, Willis GR, Datta DB, Ellins EA, Ladell K, Price DA, Guschina IA, Rees DA, James PE. Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. J Lipid Res. 2014 Oct; 55(10):2064-72. PMID: 25121984.
    Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
  14. Willis GR, Udiawar M, Evans WD, Blundell HL, James PE, Rees DA. Detailed characterisation of circulatory nitric oxide and free radical indices--is there evidence for abnormal cardiovascular homeostasis in young women with polycystic ovary syndrome? BJOG. 2014 Dec; 121(13):1596-603. PMID: 24816317.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.