Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Check out the new look and feel of Harvard Catalyst Profiles! Learn more on our About and Help pages.

Youssef Jounaidi, Ph.D.

Title
Institution
Department
Address
Phone

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Yang X, Jounaidi Y, Dai JB, Marte-Oquendo F, Halpin ES, Brown LE, Trilles R, Xu W, Daigle R, Yu B, Schaus SE, Porco JA, Forman SA. High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics. Anesthesiology. 2018 Jun 12. PMID: 29894316.
    View in: PubMed
  2. Zhou X, Desai R, Zhang Y, Stec WJ, Miller KW, Jounaidi Y. High-level production and purification in a functional state of an extrasynaptic gamma-aminobutyric acid type A receptor containing a4ß3d subunits. PLoS One. 2018; 13(1):e0191583. PMID: 29352320.
    View in: PubMed
  3. Jounaidi Y, Cotten JF, Miller KW, Forman SA. Tethering IL2 to Its Receptor IL2Rß Enhances Antitumor Activity and Expansion of Natural Killer NK92 Cells. Cancer Res. 2017 11 01; 77(21):5938-5951. PMID: 28916655.
    View in: PubMed
  4. Chiara DC, Jounaidi Y, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. General Anesthetic Binding Sites in Human a4ß3d ?-Aminobutyric Acid Type A Receptors (GABAARs). J Biol Chem. 2016 Dec 16; 291(51):26529-26539. PMID: 27821594.
    View in: PubMed
  5. Liu K, Jounaidi Y, Forman SA, Feng HJ. Etomidate uniquely modulates the desensitization of recombinant a1ß3d GABA(A) receptors. Neuroscience. 2015 Aug 06; 300:307-13. PMID: 26028470; PMCID: PMC4484732.
  6. Feng HJ, Jounaidi Y, Haburcak M, Yang X, Forman SA. Etomidate produces similar allosteric modulation in a1ß3d and a1ß3?2L GABA(A) receptors. Br J Pharmacol. 2014 Feb; 171(3):789-98. PMID: 24199598; PMCID: PMC3969089.
  7. Mupparaju S, Hou H, Lariviere JP, Swartz H, Jounaidi Y, Khan N. Repeated tumor oximetry to identify therapeutic window during metronomic cyclophosphamide treatment of 9L gliomas. Oncol Rep. 2011 Jul; 26(1):281-6. PMID: 21503586; PMCID: PMC3146786.
  8. Doloff JC, Jounaidi Y, Waxman DJ. Dual E1A oncolytic adenovirus: targeting tumor heterogeneity with two independent cancer-specific promoter elements, DF3/MUC1 and hTERT. Cancer Gene Ther. 2011 Mar; 18(3):153-66. PMID: 20865021; PMCID: PMC3010505.
  9. Doloff JC, Khan N, Ma J, Demidenko E, Swartz HM, Jounaidi Y. Increased tumor oxygenation and drug uptake during anti-angiogenic weekly low dose cyclophosphamide enhances the anti-tumor effect of weekly tirapazamine. Curr Cancer Drug Targets. 2009 Sep; 9(6):777-88. PMID: 19754361; PMCID: PMC2912211.
  10. Doloff JC, Waxman DJ, Jounaidi Y. Human telomerase reverse transcriptase promoter-driven oncolytic adenovirus with E1B-19 kDa and E1B-55 kDa gene deletions. Hum Gene Ther. 2008 Dec; 19(12):1383-400. PMID: 18771358; PMCID: PMC2715448.
  11. Chen CS, Jounaidi Y, Su T, Waxman DJ. Enhancement of intratumoral cyclophosphamide pharmacokinetics and antitumor activity in a P450 2B11-based cancer gene therapy model. Cancer Gene Ther. 2007 Dec; 14(12):935-44. PMID: 17853921; PMCID: PMC2613860.
  12. Jounaidi Y, Doloff JC, Waxman DJ. Conditionally replicating adenoviruses for cancer treatment. Curr Cancer Drug Targets. 2007 May; 7(3):285-301. PMID: 17504125; PMCID: PMC3354698.
  13. Jounaidi Y, Chen CS, Veal GJ, Waxman DJ. Enhanced antitumor activity of P450 prodrug-based gene therapy using the low Km cyclophosphamide 4-hydroxylase P450 2B11. Mol Cancer Ther. 2006 Mar; 5(3):541-55. PMID: 16546968.
    View in: PubMed
  14. Riddick DS, Lee C, Ramji S, Chinje EC, Cowen RL, Williams KJ, Patterson AV, Stratford IJ, Morrow CS, Townsend AJ, Jounaidi Y, Chen CS, Su T, Lu H, Schwartz PS, Waxman DJ. Cancer chemotherapy and drug metabolism. Drug Metab Dispos. 2005 Aug; 33(8):1083-96. PMID: 16049130.
    View in: PubMed
  15. Chen CS, Jounaidi Y, Waxman DJ. Enantioselective metabolism and cytotoxicity of R-ifosfamide and S-ifosfamide by tumor cell-expressed cytochromes P450. Drug Metab Dispos. 2005 Sep; 33(9):1261-7. PMID: 15919850.
    View in: PubMed
  16. Jounaidi Y, Waxman DJ. Use of replication-conditional adenovirus as a helper system to enhance delivery of P450 prodrug-activation genes for cancer therapy. Cancer Res. 2004 Jan 01; 64(1):292-303. PMID: 14729637.
    View in: PubMed
  17. Baldwin A, Huang Z, Jounaidi Y, Waxman DJ. Identification of novel enzyme-prodrug combinations for use in cytochrome P450-based gene therapy for cancer. Arch Biochem Biophys. 2003 Jan 01; 409(1):197-206. PMID: 12464259.
    View in: PubMed
  18. Jounaidi Y. Cytochrome P450-based gene therapy for cancer treatment: from concept to the clinic. Curr Drug Metab. 2002 Dec; 3(6):609-22. PMID: 12369889.
    View in: PubMed
  19. Jounaidi Y, Waxman DJ. Frequent, moderate-dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase-based cancer gene therapy. Cancer Res. 2001 Jun 01; 61(11):4437-44. PMID: 11389073.
    View in: PubMed
  20. Jounaidi Y, Waxman DJ. Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy. Cancer Res. 2000 Jul 15; 60(14):3761-9. PMID: 10919648.
    View in: PubMed
  21. Hecht JE, Jounaidi Y, Waxman DJ. Construction of p450-expressing tumor cell lines using retroviruses. Methods Mol Med. 2000; 35:85-94. PMID: 21390801.
    View in: PubMed
  22. Pascussi JM, Jounaidi Y, Drocourt L, Domergue J, Balabaud C, Maurel P, Vilarem MJ. Evidence for the presence of a functional pregnane X receptor response element in the CYP3A7 promoter gene. Biochem Biophys Res Commun. 1999 Jul 05; 260(2):377-81. PMID: 10403778.
    View in: PubMed
  23. Waxman DJ, Chen L, Hecht JE, Jounaidi Y. Cytochrome P450-based cancer gene therapy: recent advances and future prospects. Drug Metab Rev. 1999 May; 31(2):503-22. PMID: 10335450.
    View in: PubMed
  24. Jounaidi Y, Hecht JE, Waxman DJ. Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy. Cancer Res. 1998 Oct 01; 58(19):4391-401. PMID: 9766669.
    View in: PubMed
  25. Gábelová A, Périn-Roussel O, Jounaidi Y, Périn F. DNA adduct formation in primary mouse embryo cells induced by 7H-dibenzo[c,g]carbazole and its organ-specific carcinogenic derivatives. Environ Mol Mutagen. 1997; 30(1):56-64. PMID: 9258330.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Jounaidi's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (157)
Explore
_
Co-Authors (8)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_