Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Quang-De Nguyen, Ph.D.

Profile Picture

SNMMI-AACR Young Investigator Award

Quang-Dé Nguyen is the Scientific Director of the Lurie Family Imaging Center (DFCI), Lead Scientist in the Center for Biomedical Imaging in Oncology (DFCI), and a Research Associate in Radiology at Harvard Medical School. He received his PhD from University Pierre and Marie Curie in Paris, France, and trained as a Postdoctoral Research Fellow at Imperial College London, UK. Dr. His research and work are focused on the development and translation of novel molecular imaging strategies for the detection of cancer and early assessment of response to therapeutics, using a range of modalities including MRI, optical imaging (bioluminescence and fluorescence), CT, PET, SPECT and ultrasound imaging.

The Lurie Family Imaging Center (LFIC) is a state-of-the-art 14,000 square feet preclinical imaging facility. The studies conducted at the LFIC are focused on cancer, with an emphasis on assessment of novel cancer therapeutics, multimodality imaging of cancer, molecular imaging of pharmacodynamic efficacy, development of novel probes, and target validation.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Luo M, Berkowitz S, Nguyen Q, Yam CS, Faintuch S, Ahmed M, Collares F, Sarwar A, Weinstein JL, Brook OR. Electronic IR Group Peer Review and Learning Performed during Daily Clinical Rounds. J Vasc Interv Radiol. 2019 Apr; 30(4):594-600. PMID: 30824305.
    Citations:    Fields:    Translation:Humans
  2. Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, Brulle-Soumare L, Taylor P, Cairo S, Ryan CJ, Pease EJ, Maratea K, Travers J, Root DE, Signoretti S, Pellman D, Ashton S, Lord CJ, Barry ST, Kaelin WG. Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival. Cancer Discov. 2019 02; 9(2):230-247. PMID: 30373918; PMCID: PMC6368871.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  3. Protti A, Jones KL, Bonal DM, Qin L, Politi LS, Kravets S, Nguyen QD, Van den Abbeele AD. Development and validation of a new MRI simulation technique that can reliably estimate optimal in vivo scanning parameters in a glioblastoma murine model. PLoS One. 2018; 13(7):e0200611. PMID: 30036367.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Heinzmann K, Nguyen QD, Honess D, Smith DM, Stribbling S, Brickute D, Barnes C, Griffiths J, Aboagye E. Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using 18F-ICMT-11 and 18F-FLT PET. J Nucl Med. 2018 10; 59(10):1558-1565. PMID: 29794225; PMCID: PMC6167530.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  5. Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popovic M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE, Suvà ML. Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science. 2018 04 20; 360(6386):331-335. PMID: 29674595.
    Citations: 179     Fields:    Translation:HumansCells
  6. Gong L, Liu F, Xiong Z, Qi R, Luo Z, Gong X, Nie Q, Sun Q, Liu YF, Qing W, Wang L, Zhang L, Tang X, Huang S, Li G, Ouyang H, Xiang M, Nguyen QD, Liu Y, Li DW. Heterochromatin protects retinal pigment epithelium cells from oxidative damage by silencing p53 target genes. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):E3987-E3995. PMID: 29622681; PMCID: PMC5924883.
    Citations: 12     Fields:    Translation:AnimalsCells
  7. McBrayer SK, Olenchock BA, DiNatale GJ, Shi DD, Khanal J, Jennings RB, Novak JS, Oser MG, Robbins AK, Modiste R, Bonal D, Moslehi J, Bronson RT, Neuberg D, Nguyen QD, Signoretti S, Losman JA, Kaelin WG. Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3741-E3748. PMID: 29610306; PMCID: PMC5910822.
    Citations: 6     Fields:    Translation:AnimalsCells
  8. Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK. Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1-Specific VHHs. Cancer Immunol Res. 2018 04; 6(4):389-401. PMID: 29459478.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  9. Kedves AT, Gleim S, Liang X, Bonal DM, Sigoillot F, Harbinski F, Sanghavi S, Benander C, George E, Gokhale PC, Nguyen QD, Kirschmeier PT, Distel RJ, Jenkins J, Goldberg MS, Forrester WC. Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C. J Clin Invest. 2017 12 01; 127(12):4554-4568. PMID: 29130934; PMCID: PMC5707153.
    Citations: 12     Fields:    Translation:HumansCells
  10. Slade RL, Pisaneschi F, Nguyen QD, Smith G, Carroll L, Beckley A, Kaliszczak MA, Aboagye EO. Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography. PLoS One. 2016; 11(8):e0161427. PMID: 27552105.
    Citations: 2     Fields:    Translation:HumansCells
  11. Trousil S, Kaliszczak M, Schug Z, Nguyen QD, Tomasi G, Favicchio R, Brickute D, Fortt R, Twyman FJ, Carroll L, Kalusa A, Navaratnam N, Adejumo T, Carling D, Gottlieb E, Aboagye EO. The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth. Oncotarget. 2016 Jun 14; 7(24):37103-37120. PMID: 27206796.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  12. Ni J, Ramkissoon SH, Xie S, Goel S, Stover DG, Guo H, Luu V, Marco E, Ramkissoon LA, Kang YJ, Hayashi M, Nguyen QD, Ligon AH, Du R, Claus EB, Alexander BM, Yuan GC, Wang ZC, Iglehart JD, Krop IE, Roberts TM, Winer EP, Lin NU, Ligon KL, Zhao JJ. Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases. Nat Med. 2016 07; 22(7):723-6. PMID: 27270588; PMCID: PMC4938731.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  13. Van den Abbeele AD, Krajewski KM, Tirumani SH, Fennessy FM, DiPiro PJ, Nguyen QD, Harris GJ, Jacene HA, Lefever G, Ramaiya NH. Cancer Imaging at the Crossroads of Precision Medicine: Perspective From an Academic Imaging Department in a Comprehensive Cancer Center. J Am Coll Radiol. 2016 Apr; 13(4):365-71. PMID: 26774886.
    Citations: 1     Fields:    Translation:Humans
  14. Udemba A, Smith G, Nguyen QD, Kaliszczak M, Carroll L, Fortt R, Fuchter MJ, Aboagye EO. Design, synthesis and initial characterisation of a radiolabelled [(18)F]pyrimidoindolone probe for detecting activated caspase-3/7. Org Biomol Chem. 2015 May 21; 13(19):5418-23. PMID: 25865735.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  15. Alam IS, Arshad MA, Nguyen QD, Aboagye EO. Radiopharmaceuticals as probes to characterize tumour tissue. Eur J Nucl Med Mol Imaging. 2015 Apr; 42(4):537-61. PMID: 25647074.
    Citations: 5     Fields:    Translation:HumansAnimals
  16. Filipovic A, Lombardo Y, Faronato M, Fronato M, Abrahams J, Aboagye E, Nguyen QD, d'Aqua BB, Ridley A, Green A, Rahka E, Ellis I, Recchi C, Przulj N, Sarajlic A, Alattia JR, Fraering P, Deonarain M, Coombes RC. Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells. Breast Cancer Res Treat. 2014 Nov; 148(2):455-62. PMID: 25248409; PMCID: PMC4223543.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  17. Evans HL, Nguyen QD, Carroll LS, Kaliszczak M, Twyman FJ, Spivey AC, Aboagye EO. A bioorthogonal (68)Ga-labelling strategy for rapid in vivo imaging. Chem Commun (Camb). 2014 Aug 28; 50(67):9557-60. PMID: 25012592.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  18. Gallo J, Kamaly N, Lavdas I, Stevens E, Nguyen QD, Wylezinska-Arridge M, Aboagye EO, Long NJ. CXCR4-targeted and MMP-responsive iron oxide nanoparticles for enhanced magnetic resonance imaging. Angew Chem Int Ed Engl. 2014 Sep 01; 53(36):9550-4. PMID: 25045009; PMCID: PMC4321346.
    Citations: 33     Fields:    Translation:Animals
  19. Witney TH, Pisaneschi F, Alam IS, Trousil S, Kaliszczak M, Twyman F, Brickute D, Nguyen QD, Schug Z, Gottlieb E, Aboagye EO. Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection. J Nucl Med. 2014 Sep; 55(9):1506-12. PMID: 25012458.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  20. Sala R, Nguyen QD, Patel CB, Mann D, Steinke JH, Vilar R, Aboagye EO. Phosphorylation status of thymidine kinase 1 following antiproliferative drug treatment mediates 3'-deoxy-3'-[18F]-fluorothymidine cellular retention. PLoS One. 2014; 9(7):e101366. PMID: 25003822; PMCID: PMC4086825.
    Citations:    Fields:    Translation:HumansCells
  21. Witney TH, Carroll L, Alam IS, Chandrashekran A, Nguyen QD, Sala R, Harris R, DeBerardinis RJ, Agarwal R, Aboagye EO. A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography. Cancer Res. 2014 Mar 01; 74(5):1319-28. PMID: 24590807; PMCID: PMC3966281.
    Citations: 20     Fields:    Translation:HumansCells
  22. Trousil S, Hoppmann S, Nguyen QD, Kaliszczak M, Tomasi G, Iveson P, Hiscock D, Aboagye EO. Positron emission tomography imaging with 18F-labeled ZHER2:2891 affibody for detection of HER2 expression and pharmacodynamic response to HER2-modulating therapies. Clin Cancer Res. 2014 Mar 15; 20(6):1632-43. PMID: 24493830.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  23. George GP, Pisaneschi F, Nguyen QD, Aboagye EO. Positron emission tomographic imaging of CXCR4 in cancer: challenges and promises. Mol Imaging. 2014; 13. PMID: 25341373.
    Citations: 11     Fields:    Translation:HumansAnimals
  24. George GP, Stevens E, Åberg O, Nguyen QD, Pisaneschi F, Spivey AC, Aboagye EO. Preclinical evaluation of a CXCR4-specific (68)Ga-labelled TN14003 derivative for cancer PET imaging. Bioorg Med Chem. 2014 Jan 15; 22(2):796-803. PMID: 24365390.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  25. Alam IS, Witney TH, Tomasi G, Carroll L, Twyman FJ, Nguyen QD, Aboagye EO. Radiolabeled RGD tracer kinetics annotates differential avß 3 integrin expression linked to cell intrinsic and vessel expression. Mol Imaging Biol. 2014 Aug; 16(4):558-66. PMID: 24310722.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  26. Pisaneschi F, Slade RL, Iddon L, George GP, Nguyen QD, Spivey AC, Aboagye EO. Synthesis of a new fluorine-18 glycosylated 'click' cyanoquinoline for the imaging of epidermal growth factor receptor. J Labelled Comp Radiopharm. 2014 Feb; 57(2):92-6. PMID: 24307532.
    Citations: 6     Fields:    Translation:HumansCells
  27. Zhao L, Ashek A, Wang L, Fang W, Dabral S, Dubois O, Cupitt J, Pullamsetti SS, Cotroneo E, Jones H, Tomasi G, Nguyen QD, Aboagye EO, El-Bahrawy MA, Barnes G, Howard LS, Gibbs JS, Gsell W, He JG, Wilkins MR. Heterogeneity in lung (18)FDG uptake in pulmonary arterial hypertension: potential of dynamic (18)FDG positron emission tomography with kinetic analysis as a bridging biomarker for pulmonary vascular remodeling targeted treatments. Circulation. 2013 Sep 10; 128(11):1214-24. PMID: 23900048.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  28. George GP, Pisaneschi F, Stevens E, Nguyen QD, Åberg O, Spivey AC, Aboagye EO. Scavenging strategy for specific activity improvement: application to a new CXCR4-specific cyclopentapeptide positron emission tomography tracer. J Labelled Comp Radiopharm. 2013 Nov; 56(13):679-85. PMID: 25196030.
    Citations: 5     Fields:    Translation:HumansCells
  29. Nguyen QD, Lavdas I, Gubbins J, Smith G, Fortt R, Carroll LS, Graham MA, Aboagye EO. Temporal and spatial evolution of therapy-induced tumor apoptosis detected by caspase-3-selective molecular imaging. Clin Cancer Res. 2013 Jul 15; 19(14):3914-24. PMID: 23729364.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  30. Kaliszczak M, Trousil S, Åberg O, Perumal M, Nguyen QD, Aboagye EO. A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth. Br J Cancer. 2013 Feb 05; 108(2):342-50. PMID: 23322205.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  31. Lake MC, Nguyen QD, Ali S, Aboagye EO. Development of a novel molecular sensor for imaging estrogen receptor-coactivator protein-protein interactions. PLoS One. 2012; 7(8):e44160. PMID: 22952913.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  32. Smith G, Sala R, Carroll L, Behan K, Glaser M, Robins E, Nguyen QD, Aboagye EO. Synthesis and evaluation of nucleoside radiotracers for imaging proliferation. Nucl Med Biol. 2012 Jul; 39(5):652-65. PMID: 22321533.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  33. Åberg O, Pisaneschi F, Smith G, Nguyen QD, Stevens E, Aboagye EO. 18F-labelling of a cyclic pentapeptide inhibitor of the chemokine receptor CXCR4. J Fluorine Chem. 2012; (135):200-206.
  34. Witney TH, Alam IS, Turton DR, Smith G, Carroll L, Brickute D, Twyman FJ, Nguyen QD, Tomasi G, Awais RO, Aboagye EO. Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography. Clin Cancer Res. 2012 Feb 15; 18(4):1063-72. PMID: 22235095.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  35. Nguyen QD, Challapalli A, Smith G, Fortt R, Aboagye EO. Imaging apoptosis with positron emission tomography: 'bench to bedside' development of the caspase-3/7 specific radiotracer [(18)F]ICMT-11. Eur J Cancer. 2012 Mar; 48(4):432-40. PMID: 22226480.
    Citations: 30     Fields:    Translation:Humans
  36. Evans HL, Slade RL, Carroll L, Smith G, Nguyen QD, Iddon L, Kamaly N, Stöckmann H, Leeper FJ, Aboagye EO, Spivey AC. Copper-free click--a promising tool for pre-targeted PET imaging. Chem Commun (Camb). 2012 Jan 25; 48(7):991-3. PMID: 22158912.
    Citations: 15     Fields:    Translation:AnimalsCells
  37. Contractor KB, Kenny LM, Stebbing J, Challapalli A, Al-Nahhas A, Palmieri C, Shousha S, Lewis JS, Hogben K, De Nguyen Q, Coombes RC, Aboagye EO. Biological basis of [¹¹C]choline-positron emission tomography in patients with breast cancer: comparison with [¹8F]fluorothymidine positron emission tomography. Nucl Med Commun. 2011 Nov; 32(11):997-1004. PMID: 21862943.
    Citations: 10     Fields:    Translation:Humans
  38. Nguyen QD, Perumal M, Waldman TA, Aboagye EO. Glucose metabolism measured by [¹8F]fluorodeoxyglucose positron emission tomography is independent of PTEN/AKT status in human colon carcinoma cells. Transl Oncol. 2011 Aug; 4(4):241-8. PMID: 21804920; PMCID: PMC3140012.
    Citations: 16     
  39. Smith G, Zhao Y, Leyton J, Shan B, Nguyen QD, Perumal M, Turton D, Årstad E, Luthra SK, Robins EG, Aboagye EO. Radiosynthesis and pre-clinical evaluation of [(18)F]fluoro-[1,2-(2)H(4)]choline. Nucl Med Biol. 2011 Jan; 38(1):39-51. PMID: 21220128.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  40. Nguyen QD, Aboagye EO. Imaging the life and death of tumors in living subjects: Preclinical PET imaging of proliferation and apoptosis. Integr Biol (Camb). 2010 Oct; 2(10):483-95. PMID: 20737104.
    Citations: 8     Fields:    Translation:Animals
  41. Pisaneschi F, Nguyen QD, Shamsaei E, Glaser M, Robins E, Kaliszczak M, Smith G, Spivey AC, Aboagye EO. Development of a new epidermal growth factor receptor positron emission tomography imaging agent based on the 3-cyanoquinoline core: synthesis and biological evaluation. Bioorg Med Chem. 2010 Sep 15; 18(18):6634-45. PMID: 20797871.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  42. Smith G, Nguyen QD, Aboagye EO. Translational imaging of apoptosis. Anticancer Agents Med Chem. 2009 Nov; 9(9):958-67. PMID: 19663785.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  43. Leyton J, Smith G, Zhao Y, Perumal M, Nguyen QD, Robins E, Arstad E, Aboagye EO. [18F]fluoromethyl-[1,2-2H4]-choline: a novel radiotracer for imaging choline metabolism in tumors by positron emission tomography. Cancer Res. 2009 Oct 01; 69(19):7721-8. PMID: 19773436.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  44. Nguyen QD, Smith G, Glaser M, Perumal M, Arstad E, Aboagye EO. Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide. Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38):16375-80. PMID: 19805307.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  45. Tennant DA, Frezza C, MacKenzie ED, Nguyen QD, Zheng L, Selak MA, Roberts DL, Dive C, Watson DG, Aboagye EO, Gottlieb E. Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death. Oncogene. 2009 Nov 12; 28(45):4009-21. PMID: 19718054.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  46. Smith G, Glaser M, Perumal M, Nguyen QD, Shan B, Arstad E, Aboagye EO. Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide. J Med Chem. 2008 Dec 25; 51(24):8057-67. PMID: 19049429.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  47. Leyton J, Smith G, Lees M, Perumal M, Nguyen QD, Aigbirhio FI, Golovko O, He Q, Workman P, Aboagye EO. Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901. Mol Cancer Ther. 2008 Sep; 7(9):3112-21. PMID: 18790789.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  48. Chan F, Sun C, Perumal M, Nguyen QD, Bavetsias V, McDonald E, Martins V, Wilsher NE, Raynaud FI, Valenti M, Eccles S, Te Poele R, Workman P, Aboagye EO, Linardopoulos S. Mechanism of action of the Aurora kinase inhibitor CCT129202 and in vivo quantification of biological activity. Mol Cancer Ther. 2007 Dec; 6(12 Pt 1):3147-57. PMID: 18089709.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  49. Prévost GP, Lonchampt MO, Holbeck S, Attoub S, Zaharevitz D, Alley M, Wright J, Brezak MC, Coulomb H, Savola A, Huchet M, Chaumeron S, Nguyen QD, Forgez P, Bruyneel E, Bracke M, Ferrandis E, Roubert P, Demarquay D, Gespach C, Kasprzyk PG. Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex. Cancer Res. 2006 Sep 15; 66(18):9227-34. PMID: 16982767.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  50. Nguyen QD, Rodrigues S, Rodrigue CM, Rivat C, Grijelmo C, Bruyneel E, Emami S, Attoub S, Gespach C. Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts. Mol Cancer Ther. 2006 Aug; 5(8):2070-7. PMID: 16928828.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  51. Nguyen QD, De Wever O, Bruyneel E, Hendrix A, Xie WZ, Lombet A, Leibl M, Mareel M, Gieseler F, Bracke M, Gespach C. Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment. Oncogene. 2005 Dec 15; 24(56):8240-51. PMID: 16091733.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  52. Zimber A, Nguyen QD, Gespach C. Nuclear bodies and compartments: functional roles and cellular signalling in health and disease. Cell Signal. 2004 Oct; 16(10):1085-104. PMID: 15240004.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  53. De Wever O, Nguyen QD, Van Hoorde L, Bracke M, Bruyneel E, Gespach C, Mareel M. Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac. FASEB J. 2004 Jun; 18(9):1016-8. PMID: 15059978.
    Citations: 143     Fields:    Translation:HumansCells
  54. Rodrigues S, Attoub S, Nguyen QD, Bruyneel E, Rodrigue CM, Westley BR, May FE, Thim L, Mareel M, Emami S, Gespach C. Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells. Oncogene. 2003 Jul 17; 22(29):4488-97. PMID: 12881705.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  55. Rodrigues S, Van Aken E, Van Bocxlaer S, Attoub S, Nguyen QD, Bruyneel E, Westley BR, May FE, Thim L, Mareel M, Gespach C, Emami S. Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling. FASEB J. 2003 Jan; 17(1):7-16. PMID: 12522107.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  56. Régnauld K, Nguyen QD, Vakaet L, Bruyneel E, Launay JM, Endo T, Mareel M, Gespach C, Emami S. G-protein alpha(olf) subunit promotes cellular invasion, survival, and neuroendocrine differentiation in digestive and urogenital epithelial cells. Oncogene. 2002 Jun 06; 21(25):4020-31. PMID: 12037684.
    Citations: 7     Fields:    Translation:HumansCells
  57. Nguyen QD, Faivre S, Bruyneel E, Rivat C, Seto M, Endo T, Mareel M, Emami S, Gespach C. RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion. FASEB J. 2002 Apr; 16(6):565-76. PMID: 11919159.
    Citations: 13     Fields:    Translation:Cells
  58. Faivre S, Régnauld K, Bruyneel E, Nguyen QD, Mareel M, Emami S, Gespach C. Suppression of cellular invasion by activated G-protein subunits Galphao, Galphai1, Galphai2, and Galphai3 and sequestration of Gbetagamma. Mol Pharmacol. 2001 Aug; 60(2):363-72. PMID: 11455024.
    Citations: 7     Fields:    Translation:AnimalsCells
  59. Rodrigues S, Nguyen QD, Faivre S, Bruyneel E, Thim L, Westley B, May F, Flatau G, Mareel M, Gespach C, Emami S. Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase- and thromboxane A2 receptor-dependent signaling pathways. FASEB J. 2001 Jul; 15(9):1517-28. PMID: 11427483.
    Citations: 9     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Nguyen's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (391)
Co-Authors (55)
Similar People (60)
Same Department 
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.