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Leonid Lecca, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Peloquin CA, Phillips PPJ, Mitnick CD, Eisenach K, Patientia RF, Lecca L, Gotuzzo E, Gandhi NR, Butler D, Diacon AH, Martel B, Santillan J, Hunt KR, Vargas D, von Groote-Bidlingmaier F, Seas C, Dianis N, Moreno-Martinez A, Kaur P, Horsburgh CR. Increased Doses Lead to Higher Drug Exposures of Levofloxacin for the Treatment of Tuberculosis. Antimicrob Agents Chemother. 2018 Jul 16. PMID: 30012767.
    View in: PubMed
  2. Thakore N, Norville R, Franke M, Calderon R, Lecca L, Villanueva M, Murray MB, Cooney CG, Chandler DP, Holmberg RC. Automated TruTip nucleic acid extraction and purification from raw sputum. PLoS One. 2018; 13(7):e0199869. PMID: 29975759.
    View in: PubMed
  3. Velásquez GE, Brooks MB, Coit JM, Pertinez H, Vargas Vásquez D, Sánchez Garavito E, Calderón RI, Jiménez J, Tintaya K, Peloquin CA, Osso E, Tierney DB, Seung KJ, Lecca L, Davies GR, Mitnick CD. Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis: A Randomized Controlled Trial. Am J Respir Crit Care Med. 2018 Jun 29. PMID: 29954183.
    View in: PubMed
  4. Nelson AK, Miller AC, Munoz M, Rumaldo N, Kammerer B, Vibbert M, Lundy S, Soplapuco G, Lecca L, Condeso A, Valdivia Y, Atwood SA, Shin SS. CASITA: a controlled pilot study of community-based family coaching to stimulate early child development in Lima, Peru. BMJ Paediatr Open. 2018; 2(1):e000268. PMID: 29862331.
    View in: PubMed
  5. Linger Y, Knickerbocker C, Sipes D, Golova J, Franke M, Calderon R, Lecca L, Thakore N, Holmberg R, Qu P, Kukhtin A, Murray MB, Cooney CG, Chandler DP. Genotyping Multidrug-Resistant Mycobacterium tuberculosis from Primary Sputum and Decontaminated Sediment with an Integrated Microfluidic Amplification Microarray Test. J Clin Microbiol. 2018 Mar; 56(3). PMID: 29305543.
    View in: PubMed
  6. Zelner J, Murray M, Becerra M, Galea J, Lecca L, Calderon R, Yataco R, Zhang Z, Cohen T. Protective effects of household-based TB interventions are robust to neighbourhood-level variation in exposure risk in Lima, Peru: a model-based analysis. Int J Epidemiol. 2018 Feb 01; 47(1):185-192. PMID: 29025111.
    View in: PubMed
  7. McLaughlin MM, Franke MF, Muñoz M, Nelson AK, Saldaña O, Cruz JS, Wong M, Zhang Z, Lecca L, Ticona E, Arevalo J, Sanchez E, Sebastián JL, Shin S. Community-Based Accompaniment with Supervised Antiretrovirals for HIV-Positive Adults in Peru: A Cluster-Randomized Trial. AIDS Behav. 2018 Jan; 22(1):287-296. PMID: 28074421.
    View in: PubMed
  8. Aibana O, Franke MF, Huang CC, Galea JT, Calderon R, Zhang Z, Becerra MC, Smith ER, Contreras C, Yataco R, Lecca L, Murray MB. Vitamin E Status Is Inversely Associated with Risk of Incident Tuberculosis Disease among Household Contacts. J Nutr. 2018 01 01; 148(1):56-62. PMID: 29378042.
    View in: PubMed
  9. Byrne AL, Marais BJ, Mitnick CD, Garden FL, Lecca L, Contreras C, Yauri Y, Garcia F, Marks GB. Feasibility and yield of screening for non-communicable diseases among treated tuberculosis patients in Peru. Int J Tuberc Lung Dis. 2018 Jan 01; 22(1):86-92. PMID: 29297431.
    View in: PubMed
  10. Shu E, Sobieszczyk ME, Sal Y Rosas VG, Segura P, Galea JT, Lecca L, Sanchez J, Lama JR. Knowledge of tuberculosis and vaccine trial preparedness in Lima, Peru. Int J Tuberc Lung Dis. 2017 Dec 01; 21(12):1288-1293. PMID: 29297450.
    View in: PubMed
  11. Bouton TC, Phillips PPJ, Mitnick CD, Peloquin CA, Eisenach K, Patientia RF, Lecca L, Gotuzzo E, Gandhi NR, Butler D, Diacon AH, Martel B, Santillan J, Hunt KR, Vargas D, von Groote-Bidlingmaier F, Seas C, Dianis N, Moreno-Martinez A, Horsburgh CR. An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial. Trials. 2017 Nov 25; 18(1):563. PMID: 29178937.
    View in: PubMed
  12. Nathavitharana RR, Shi CX, Chindelevitch L, Calderon R, Zhang Z, Galea JT, Contreras C, Yataco R, Lecca L, Becerra MC, Murray MB, Cohen T. Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru. Emerg Infect Dis. 2017 11; 23(11):1887-1890. PMID: 29048297.
    View in: PubMed
  13. Rodriguez CA, Smith ER, Villamor E, Zavaleta N, Respicio-Torres G, Contreras C, Perea S, Jimenez J, Tintaya K, Lecca L, Murray MB, Franke MF. Development and Validation of a Food Frequency Questionnaire to Estimate Intake among Children and Adolescents in Urban Peru. Nutrients. 2017 Oct 14; 9(10). PMID: 29036893.
    View in: PubMed
  14. Scuffell J, Boccia D, Garcia Velarde F, Leon SR, Raviola G, Lecca L, Galea JT. Mental disorders and drug/alcohol use in patients commencing extensively drug-resistant tuberculosis treatment. Public Health Action. 2017 Sep 21; 7(3):237-239. PMID: 29201659.
    View in: PubMed
  15. Aibana O, Franke MF, Huang CC, Galea JT, Calderon R, Zhang Z, Becerra MC, Smith ER, Ronnenberg AG, Contreras C, Yataco R, Lecca L, Murray MB. Impact of Vitamin A and Carotenoids on the Risk of Tuberculosis Progression. Clin Infect Dis. 2017 Sep 15; 65(6):900-909. PMID: 28531276.
    View in: PubMed
  16. Peloquin CA, Velásquez GE, Lecca L, Calderón RI, Coit J, Milstein M, Osso E, Jimenez J, Tintaya K, Garavito ES, Vasquez DV, Mitnick CD, Davies G. Erratum for Peloquin et al., "Pharmacokinetic Evidence from the HIRIF Trial To Support Increased Doses of Rifampin for Tuberculosis". Antimicrob Agents Chemother. 2017 Sep; 61(9). PMID: 28839086.
    View in: PubMed
  17. Calderón RI, Velásquez GE, Becerra MC, Zhang Z, Contreras CC, Yataco RM, Galea JT, Lecca LW, Kritski AL, Murray MB, Mitnick CD. Prevalence of pyrazinamide resistance and Wayne assay performance analysis in a tuberculosis cohort in Lima, Peru. Int J Tuberc Lung Dis. 2017 08 01; 21(8):894-901. PMID: 28786798.
    View in: PubMed
  18. Peloquin CA, Velásquez GE, Lecca L, Calderón RI, Coit J, Milstein M, Osso E, Jimenez J, Tintaya K, Sanchez Garavito E, Vargas Vasquez D, Mitnick CD, Davies G. Pharmacokinetic Evidence from the HIRIF Trial To Support Increased Doses of Rifampin for Tuberculosis. Antimicrob Agents Chemother. 2017 08; 61(8). PMID: 28559269.
    View in: PubMed
  19. Byrne AL, Marais BJ, Mitnick CD, Garden FL, Lecca L, Contreras C, Yauri Y, Garcia F, Marks GB. Chronic airflow obstruction after successful treatment of multidrug-resistant tuberculosis. ERJ Open Res. 2017 Jul; 3(3). PMID: 28717643.
    View in: PubMed
  20. Lecca L, Galea J, Contreras CC, Millones AK, Clendenes M, Yuen CM. Challenges in tuberculosis/HIV management in a country with a concentrated HIV epidemic. AIDS. 2017 Jun 01; 31(9):1207-1209. PMID: 28492390.
    View in: PubMed
  21. Lecca L, Galea J, Contreras CC, Millones AK, Clendenes M, Yuen CM. Challenges in TB/HIV management in a country with a concentrated HIV epidemic. AIDS. 2017 Mar 28. PMID: 28353540.
    View in: PubMed
  22. Velásquez GE, Calderon RI, Mitnick CD, Becerra MC, Huang CC, Zhang Z, Contreras CC, Yataco RM, Galea JT, Lecca LW, Murray MB. Erratum for Velásquez et al., Pyrazinamide Resistance Assays and Two-Month Sputum Culture Status in Patients with Multidrug-Resistant Tuberculosis. Antimicrob Agents Chemother. 2017 Mar; 61(3). PMID: 28232308.
    View in: PubMed
  23. Contreras CC, Millones AK, Santa Cruz J, Aguilar M, Clendenes M, Toranzo M, Llaro K, Lecca L, Becerra MC, Yuen CM. Addressing tuberculosis patients' medical and socio-economic needs: a comprehensive programmatic approach. Trop Med Int Health. 2017 04; 22(4):505-511. PMID: 28117937.
    View in: PubMed
  24. Chiang SS, Roche S, Contreras C, Del Castillo H, Canales P, Jimenez J, Tintaya K, Becerra MC, Lecca L. Barriers to the treatment of childhood tuberculous infection and tuberculosis disease: a qualitative study. Int J Tuberc Lung Dis. 2017 02 01; 21(2):154-160. PMID: 28234078.
    View in: PubMed
  25. Aibana O, Acharya X, Huang CC, Becerra MC, Galea JT, Chiang SS, Contreras C, Calderon R, Yataco R, Velásquez GE, Tintaya K, Jimenez J, Lecca L, Murray MB. Nutritional Status and Tuberculosis Risk in Adult and Pediatric Household Contacts. PLoS One. 2016; 11(11):e0166333. PMID: 27835678.
    View in: PubMed
  26. Velásquez GE, Calderon RI, Mitnick CD, Becerra MC, Huang CC, Zhang Z, Contreras CC, Yataco RM, Galea JT, Lecca LW, Murray MB. Pyrazinamide Resistance Assays and Two-Month Sputum Culture Status in Patients with Multidrug-Resistant Tuberculosis. Antimicrob Agents Chemother. 2016 11; 60(11):6766-6773. PMID: 27600032.
    View in: PubMed
  27. Milstein M, Lecca L, Peloquin C, Mitchison D, Seung K, Pagano M, Coleman D, Osso E, Coit J, Vargas Vasquez DE, Sanchez Garavito E, Calderon R, Contreras C, Davies G, Mitnick CD. Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial. BMC Infect Dis. 2016 08 27; 16(1):453. PMID: 27567500; PMCID: PMC5002098.
  28. Chiang SS, Starke JR, Miller AC, Cruz AT, Del Castillo H, Valdivia WJ, Tunque G, García F, Contreras C, Lecca L, Alarcón VA, Becerra MC. Baseline Predictors of Treatment Outcomes in Children With Multidrug-Resistant Tuberculosis: A Retrospective Cohort Study. Clin Infect Dis. 2016 Oct 15; 63(8):1063-71. PMID: 27458026.
    View in: PubMed
  29. Odone A, Calderon R, Becerra MC, Zhang Z, Contreras CC, Yataco R, Galea J, Lecca L, Bonds MH, Mitnick CD, Murray MB. Acquired and Transmitted Multidrug Resistant Tuberculosis: The Role of Social Determinants. PLoS One. 2016; 11(1):e0146642. PMID: 26765328; PMCID: PMC4713093.
  30. Chiang SS, Roche S, Contreras C, Alarcón V, Del Castillo H, Becerra MC, Lecca L. Barriers to the diagnosis of childhood tuberculosis: a qualitative study. Int J Tuberc Lung Dis. 2015 Oct; 19(10):1144-52. PMID: 26459524.
    View in: PubMed
  31. Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Manjourides J, Grenfell BT, Cohen T. Identifying Hotspots of Multidrug-Resistant Tuberculosis Transmission Using Spatial and Molecular Genetic Data. J Infect Dis. 2016 Jan 15; 213(2):287-94. PMID: 26175455; PMCID: PMC4690150 [Available on 01/15/17].
  32. Byrne AL, Marais BJ, Mitnick CD, Lecca L, Marks GB. Risk factors for and origins of COPD. Lancet. 2015 May 02; 385(9979):1723-1724. PMID: 25943930.
    View in: PubMed
  33. Byrne AL, Marais BJ, Mitnick CD, Lecca L, Marks GB. Tuberculosis and chronic respiratory disease: a systematic review. Int J Infect Dis. 2015 Mar; 32:138-46. PMID: 25809770.
    View in: PubMed
  34. Huang CC, Tchetgen ET, Becerra MC, Cohen T, Galea J, Calderon R, Yataco R, Contreras C, Zhang ZB, Lecca L, Murray M. Cigarette smoking among tuberculosis patients increases risk of transmission to child contacts. Int J Tuberc Lung Dis. 2014 Nov; 18(11):1285-91. PMID: 25299859.
    View in: PubMed
  35. Franke MF, Nelson AK, Muñoz M, Cruz JS, Atwood S, Lecca L, Shin SS. Validation of 2 Spanish-Language Scales to Assess HIV-Related Stigma in Communities. J Int Assoc Provid AIDS Care. 2015 Nov-Dec; 14(6):527-35. PMID: 25294853.
    View in: PubMed
  36. Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Grenfell BT, Cohen T. Age-specific risks of tuberculosis infection from household and community exposures and opportunities for interventions in a high-burden setting. Am J Epidemiol. 2014 Oct 15; 180(8):853-61. PMID: 25190676; PMCID: PMC4188339.
  37. Del Castillo-Barrientos H, Centeno-Luque G, Untiveros-Tello A, Simms B, Lecca L, Nelson AK, Lastimoso C, Shin S. Clinical presentation of children with pulmonary tuberculosis: 25 years of experience in Lima, Peru. Int J Tuberc Lung Dis. 2014 Sep; 18(9):1066-73. PMID: 25189554.
    View in: PubMed
  38. Chiang SS, Cruz AT, Del Castillo H, Contreras C, Becerra MC, Lecca L. Evaluation of health-care providers' knowledge of childhood tuberculosis in Lima, Peru. Paediatr Int Child Health. 2015 Feb; 35(1):29-35. PMID: 25161060.
    View in: PubMed
  39. Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Grenfell BT, Cohen T. Bacillus Calmette-Guérin and isoniazid preventive therapy protect contacts of patients with tuberculosis. Am J Respir Crit Care Med. 2014 Apr 01; 189(7):853-9. PMID: 24592878; PMCID: PMC4225829.
  40. Franke MF, del Castillo H, Pereda Y, Lecca L, Cárdenas L, Fuertes J, Murray MB, Bayona J, Becerra MC. Modifiable factors associated with tuberculosis disease in children: a case-control study. Pediatr Infect Dis J. 2014 Jan; 33(1):109-11. PMID: 24064556.
    View in: PubMed
  41. Franke MF, Del Castillo H, Pereda Y, Lecca L, Fuertes J, Cárdenas L, Becerra MC, Bayona J, Murray M. Parasite infection and tuberculosis disease among children: a case-control study. Am J Trop Med Hyg. 2014 Feb; 90(2):279-82. PMID: 24379242; PMCID: PMC3919232.
  42. Huang CC, Tchetgen ET, Becerra MC, Cohen T, Hughes KC, Zhang Z, Calderon R, Yataco R, Contreras C, Galea J, Lecca L, Murray M. The effect of HIV-related immunosuppression on the risk of tuberculosis transmission to household contacts. Clin Infect Dis. 2014 Mar; 58(6):765-74. PMID: 24368620; PMCID: PMC3935504.
  43. Minnery M, Contreras C, Pérez R, Solórzano N, Tintaya K, Jimenez J, Soto S, Lecca L. A cross sectional study of knowledge and attitudes towards tuberculosis amongst front-line tuberculosis personnel in high burden areas of Lima, Peru. PLoS One. 2013; 8(9):e75698. PMID: 24069437; PMCID: PMC3777965.
  44. Galea JT, Contreras C, Lecca L, Shin S, Lobatón R, Zhang Z, Calderón R, Murray M, Becerra MC. RAPID HOME-BASED HIV TESTING TO REDUCE COSTS IN A LARGE TUBERCULOSIS COHORT STUDY. Public Health Action. 2013 Jun 21; 3(2):172-174. PMID: 25580381.
    View in: PubMed
  45. Fraser HS, Thomas D, Tomaylla J, Garcia N, Lecca L, Murray M, Becerra MC. Adaptation of a web-based, open source electronic medical record system platform to support a large study of tuberculosis epidemiology. BMC Med Inform Decis Mak. 2012 Nov 07; 12:125. PMID: 23131180; PMCID: PMC3531253.
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