Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Kevin Struhl, PH.D.

Title
Institution
Department
Address
Phone
Fax

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA107486 (STRUHL, KEVIN) May 25, 2004 - Apr 30, 2021
    NIH/NCI
    Genomic targets of oncoproteins and tumor suppressors
    Role: Principal Investigator
  2. R13CA078317 (STRUHL, KEVIN) Jul 1, 1998 - Jun 30, 1999
    NIH/NCI
    TRANSCRIPTIONAL REG IN CELL GROWTH AND DEVELOPMENT
    Role: Principal Investigator
  3. R01GM053720 (STRUHL, KEVIN) Sep 30, 1995 - Dec 31, 2009
    NIH/NIGMS
    Molecular Mechanisms of Global Represion in Yeast
    Role: Principal Investigator
  4. R01CA065965 (STRUHL, KEVIN) Sep 7, 1995 - Jun 30, 2001
    NIH/NCI
    CELLULAR TRANSFORMATION BY AP-1 TRANSCRIPTION FACTORS
    Role: Principal Investigator
  5. R01GM046555 (STRUHL, KEVIN) Aug 1, 1991 - Jul 31, 1995
    NIH/NIGMS
    DIMERIZATION &DNA BINDING SPECIFICITY OF BZIP PROTEINS
    Role: Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Struhl Laboratory - Plasmids (766), S. cerevisiae strains (1018) and S. pombe strains (2)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Petrenko N, Jin Y, Dong L, Wong KH, Struhl K. Requirements for RNA polymerase II preinitiation complex formation in vivo. Elife. 2019 Jan 25; 8. PMID: 30681409.
    Citations:    Fields:    
  2. Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa EJ, Almada LL, Mahurkar-Joshi S, Williams J, Tirado-Rodriguez AB, Huerta-Yepez S, Karavias D, Kourea H, Poultsides GA, Struhl K, Dawson DW, Donahue TR, Fernández-Zapico ME, Iliopoulos D. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Gut. 2018 Oct 18. PMID: 30337373.
    Citations:    Fields:    
  3. Moqtaderi Z, Geisberg JV, Struhl K. Extensive Structural Differences of Closely Related 3' mRNA Isoforms: Links to Pab1 Binding and mRNA Stability. Mol Cell. 2018 Dec 06; 72(5):849-861.e6. PMID: 30318446.
    Citations:    
  4. Li BB, Qian C, Gameiro PA, Liu CC, Jiang T, Roberts TM, Struhl K, Zhao JJ. Targeted profiling of RNA translation reveals mTOR-4EBP1/2-independent translation regulation of mRNAs encoding ribosomal proteins. Proc Natl Acad Sci U S A. 2018 10 02; 115(40):E9325-E9332. PMID: 30224479.
    Citations:    Fields:    Translation:HumansCells
  5. Gameiro PA, Struhl K. Nutrient Deprivation Elicits a Transcriptional and Translational Inflammatory Response Coupled to Decreased Protein Synthesis. Cell Rep. 2018 Aug 07; 24(6):1415-1424. PMID: 30089253.
    Citations:    Fields:    
  6. Ji Z, He L, Rotem A, Janzer A, Cheng CS, Regev A, Struhl K. Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation. Nat Commun. 2018 05 25; 9(1):2068. PMID: 29802342.
    Citations:    Fields:    Translation:HumansCells
  7. Petrenko N, Jin Y, Wong KH, Struhl K. Correction: Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo. Elife. 2017 09 18; 6. PMID: 28920856.
    Citations: 1     Fields:    
  8. Jin Y, Eser U, Struhl K, Churchman LS. The Ground State and Evolution of Promoter Region Directionality. Cell. 2017 Aug 24; 170(5):889-898.e10. PMID: 28803729.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  9. Petrenko N, Jin Y, Wong KH, Struhl K. Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo. Elife. 2017 07 12; 6. PMID: 28699889.
    Citations: 2     Fields:    Translation:AnimalsCells
  10. Henry WS, Hendrickson DG, Beca F, Glass B, Lindahl-Allen M, He L, Ji Z, Struhl K, Beck AH, Rinn JL, Toker A. LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer. Oncotarget. 2016 Dec 13; 7(50):81981-81994. PMID: 27626181.
    Citations: 2     Fields:    Translation:HumansCells
  11. Petrenko N, Jin Y, Wong KH, Struhl K. Mediator Undergoes a Compositional Change during Transcriptional Activation. Mol Cell. 2016 11 03; 64(3):443-454. PMID: 27773675.
    Citations: 12     Fields:    Translation:AnimalsCells
  12. Miotto B, Ji Z, Struhl K. Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):E4810-9. PMID: 27436900; PMCID: PMC4995967.
    Citations: 19     Fields:    Translation:HumansCells
  13. Ji Z, Song R, Huang H, Regev A, Struhl K. Transcriptome-scale RNase-footprinting of RNA-protein complexes. Nat Biotechnol. 2016 Apr; 34(4):410-3. PMID: 26900662; PMCID: PMC4824641.
    Citations: 10     Fields:    Translation:HumansCells
  14. Ji Z, Song R, Regev A, Struhl K. Many lncRNAs, 5'UTRs, and pseudogenes are translated and some are likely to express functional proteins. Elife. 2015 Dec 19; 4:e08890. PMID: 26687005; PMCID: PMC4739776.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  15. Rotem A, Janzer A, Izar B, Ji Z, Doench JG, Garraway LA, Struhl K. Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation. Proc Natl Acad Sci U S A. 2015 May 05; 112(18):5708-13. PMID: 25902495; PMCID: PMC4426412.
    Citations: 10     Fields:    Translation:HumansCells
  16. Jin Y, Geisberg JV, Moqtaderi Z, Ji Z, Hoque M, Tian B, Struhl K. Mapping 3' mRNA isoforms on a genomic scale. Curr Protoc Mol Biol. 2015 Apr 01; 110:4.23.1-17. PMID: 25827089; PMCID: PMC4397975.
    Citations:    Fields:    
  17. Fleming JD, Giresi PG, Lindahl-Allen M, Krall EB, Lieb JD, Struhl K. STAT3 acts through pre-existing nucleosome-depleted regions bound by FOS during an epigenetic switch linking inflammation to cancer. Epigenetics Chromatin. 2015; 8:7. PMID: 25784959; PMCID: PMC4362815.
    Citations: 4     Fields:    
  18. Janzer A, German NJ, Gonzalez-Herrera KN, Asara JM, Haigis MC, Struhl K. Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells. Proc Natl Acad Sci U S A. 2014 Jul 22; 111(29):10574-9. PMID: 25002509; PMCID: PMC4115496.
    Citations: 75     Fields:    Translation:HumansCells
  19. Wong KH, Jin Y, Struhl K. TFIIH phosphorylation of the Pol II CTD stimulates mediator dissociation from the preinitiation complex and promoter escape. Mol Cell. 2014 May 22; 54(4):601-12. PMID: 24746699; PMCID: PMC4035452.
    Citations: 37     Fields:    Translation:AnimalsCells
  20. Moqtaderi Z, Geisberg JV, Struhl K. Secondary structures involving the poly(A) tail and other 3' sequences are major determinants of mRNA isoform stability in yeast. Microb Cell. 2014 Apr; 1(4):137-139. PMID: 25279376.
    Citations: 2     
  21. Struhl K. Is DNA methylation of tumour suppressor genes epigenetic? Elife. 2014 Mar 12; 3:e02475. PMID: 24623307; PMCID: PMC3949415.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  22. Geisberg JV, Moqtaderi Z, Fan X, Ozsolak F, Struhl K. Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast. Cell. 2014 Feb 13; 156(4):812-24. PMID: 24529382; PMCID: PMC3939777.
    Citations: 63     Fields:    Translation:AnimalsCells
  23. Moqtaderi Z, Geisberg JV, Jin Y, Fan X, Struhl K. Species-specific factors mediate extensive heterogeneity of mRNA 3' ends in yeasts. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):11073-8. PMID: 23776204; PMCID: PMC3703967.
    Citations: 18     Fields:    Translation:AnimalsCells
  24. Fleming JD, Pavesi G, Benatti P, Imbriano C, Mantovani R, Struhl K. NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors. Genome Res. 2013 Aug; 23(8):1195-209. PMID: 23595228; PMCID: PMC3730095.
    Citations: 34     Fields:    Translation:HumansCells
  25. Struhl K, Segal E. Determinants of nucleosome positioning. Nat Struct Mol Biol. 2013 Mar; 20(3):267-73. PMID: 23463311; PMCID: PMC3740156.
    Citations: 156     Fields:    Translation:AnimalsCells
  26. Hirsch HA, Iliopoulos D, Struhl K. Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):972-7. PMID: 23277563; PMCID: PMC3549132.
    Citations: 130     Fields:    Translation:HumansAnimalsCells
  27. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012 Sep 06; 489(7414):57-74. PMID: 22955616.
    Citations: 3893     Fields:    Translation:HumansAnimalsCells
  28. Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci U S A. 2012 Sep 04; 109(36):14470-5. PMID: 22908280; PMCID: PMC3437881.
    Citations: 42     Fields:    Translation:HumansCells
  29. Hughes AL, Jin Y, Rando OJ, Struhl K. A functional evolutionary approach to identify determinants of nucleosome positioning: a unifying model for establishing the genome-wide pattern. Mol Cell. 2012 Oct 12; 48(1):5-15. PMID: 22885008.
    Citations: 59     Fields:    Translation:AnimalsCells
  30. Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature. 2012 Jul 05; 487(7405):114-8. PMID: 22722849; PMCID: PMC3412143.
    Citations: 126     Fields:    Translation:HumansAnimalsCells
  31. Yuan CC, Matthews AG, Jin Y, Chen CF, Chapman BA, Ohsumi TK, Glass KC, Kutateladze TG, Borowsky ML, Struhl K, Oettinger MA. Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes. Cell Rep. 2012 Feb 23; 1(2):83-90. PMID: 22720264; PMCID: PMC3377377.
    Citations: 21     Fields:    Translation:AnimalsCells
  32. Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, Ogata H, Karin M, Struhl K, Hadzopoulou-Cladaras M, Iliopoulos D. An HNF4a-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell. 2011 Dec 09; 147(6):1233-47. PMID: 22153071; PMCID: PMC3251960.
    Citations: 168     Fields:    Translation:HumansAnimalsCells
  33. Wong KH, Struhl K. The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein. Genes Dev. 2011 Dec 01; 25(23):2525-39. PMID: 22156212; PMCID: PMC3243062.
    Citations: 47     Fields:    Translation:AnimalsCells
  34. Lee JJ, Drakaki A, Iliopoulos D, Struhl K. MiR-27b targets PPAR? to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells. Oncogene. 2012 Aug 16; 31(33):3818-25. PMID: 22120719; PMCID: PMC3290753.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  35. Krebs AR, Karmodiya K, Lindahl-Allen M, Struhl K, Tora L. SAGA and ATAC histone acetyl transferase complexes regulate distinct sets of genes and ATAC defines a class of p300-independent enhancers. Mol Cell. 2011 Nov 04; 44(3):410-423. PMID: 22055187; PMCID: PMC4641564.
    Citations: 55     Fields:    Translation:HumansCells
  36. Miotto B, Struhl K. JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress. Mol Cell. 2011 Oct 07; 44(1):62-71. PMID: 21856198; PMCID: PMC3190045.
    Citations: 18     Fields:    Translation:HumansCells
  37. Tirosh I, Wong KH, Barkai N, Struhl K. Extensive divergence of yeast stress responses through transitions between induced and constitutive activation. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16693-8. PMID: 21930916; PMCID: PMC3189053.
    Citations: 13     Fields:    Translation:AnimalsCells
  38. Iliopoulos D, Rotem A, Struhl K. Inhibition of miR-193a expression by Max and RXRa activates K-Ras and PLAU to mediate distinct aspects of cellular transformation. Cancer Res. 2011 Aug 01; 71(15):5144-53. PMID: 21670079; PMCID: PMC3148313.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  39. Esberg A, Moqtaderi Z, Fan X, Lu J, Struhl K, Byström A. Iwr1 protein is important for preinitiation complex formation by all three nuclear RNA polymerases in Saccharomyces cerevisiae. PLoS One. 2011; 6(6):e20829. PMID: 21695216; PMCID: PMC3112208.
    Citations: 7     Fields:    Translation:AnimalsCells
  40. Polytarchou C, Iliopoulos D, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, Tsichlis PN. Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Res. 2011 Jul 01; 71(13):4720-31. PMID: 21555366; PMCID: PMC3129420.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  41. Iliopoulos D, Hirsch HA, Struhl K. Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types. Cancer Res. 2011 May 01; 71(9):3196-201. PMID: 21415163; PMCID: PMC3085572.
    Citations: 128     Fields:    Translation:HumansAnimalsCells
  42. Iliopoulos D, Hirsch HA, Wang G, Struhl K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1397-402. PMID: 21220315; PMCID: PMC3029760.
    Citations: 195     Fields:    Translation:HumansAnimalsCells
  43. Katan-Khaykovich Y, Struhl K. Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1296-301. PMID: 21220302; PMCID: PMC3029712.
    Citations: 29     Fields:    Translation:AnimalsCells
  44. Locke G, Tolkunov D, Moqtaderi Z, Struhl K, Morozov AV. High-throughput sequencing reveals a simple model of nucleosome energetics. Proc Natl Acad Sci U S A. 2010 Dec 07; 107(49):20998-1003. PMID: 21084631; PMCID: PMC3000311.
    Citations: 31     Fields:    Translation:HumansCells
  45. Fan X, Moqtaderi Z, Jin Y, Zhang Y, Liu XS, Struhl K. Nucleosome depletion at yeast terminators is not intrinsic and can occur by a transcriptional mechanism linked to 3'-end formation. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17945-50. PMID: 20921369.
    Citations: 38     Fields:    Translation:Cells
  46. Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell. 2010 Sep 10; 39(5):761-72. PMID: 20832727; PMCID: PMC2938080.
    Citations: 157     Fields:    Translation:HumansAnimalsCells
  47. Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K. STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell. 2010 Aug 27; 39(4):493-506. PMID: 20797623; PMCID: PMC2929389.
    Citations: 306     Fields:    Translation:HumansAnimalsCells
  48. Zhang Y, Moqtaderi Z, Rattner BP, Euskirchen G, Snyder M, Kadonaga JT, Liu XS, Struhl K. Evidence against a genomic code for nucleosome positioning. Reply to "Nucleosome sequence preferences influence in vivo nucleosome organization.". Nat Struct Mol Biol. 2010 Aug; 17(8):920-3. PMID: 20683474; PMCID: PMC4742340.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  49. Yang A, Zhu Z, Kettenbach A, Kapranov P, McKeon F, Gingeras TR, Struhl K. Genome-wide mapping indicates that p73 and p63 co-occupy target sites and have similar dna-binding profiles in vivo. PLoS One. 2010 Jul 14; 5(7):e11572. PMID: 20644729; PMCID: PMC2904373.
    Citations: 20     Fields:    Translation:HumansCells
  50. Moqtaderi Z, Wang J, Raha D, White RJ, Snyder M, Weng Z, Struhl K. Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cells. Nat Struct Mol Biol. 2010 May; 17(5):635-40. PMID: 20418883; PMCID: PMC3350333.
    Citations: 96     Fields:    Translation:HumansCells
  51. Hirsch HA, Iliopoulos D, Joshi A, Zhang Y, Jaeger SA, Bulyk M, Tsichlis PN, Shirley Liu X, Struhl K. A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases. Cancer Cell. 2010 Apr 13; 17(4):348-61. PMID: 20385360; PMCID: PMC2854678.
    Citations: 104     Fields:    Translation:HumansCells
  52. Raha D, Wang Z, Moqtaderi Z, Wu L, Zhong G, Gerstein M, Struhl K, Snyder M. Close association of RNA polymerase II and many transcription factors with Pol III genes. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3639-44. PMID: 20139302; PMCID: PMC2840497.
    Citations: 96     Fields:    Translation:HumansCells
  53. Miotto B, Struhl K. HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin. Mol Cell. 2010 Jan 15; 37(1):57-66. PMID: 20129055; PMCID: PMC2818871.
    Citations: 93     Fields:    Translation:HumansCells
  54. Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell. 2009 Nov 13; 139(4):693-706. PMID: 19878981; PMCID: PMC2783826.
    Citations: 531     Fields:    Translation:HumansAnimalsCells
  55. Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou IG, Struhl K, Tsichlis PN. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Sci Signal. 2009 Oct 13; 2(92):ra62. PMID: 19825827; PMCID: PMC2862216.
    Citations: 99     Fields:    Translation:HumansAnimalsCells
  56. Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res. 2009 Oct 01; 69(19):7507-11. PMID: 19752085; PMCID: PMC2756324.
    Citations: 356     Fields:    Translation:HumansAnimalsCells
  57. Auerbach RK, Euskirchen G, Rozowsky J, Lamarre-Vincent N, Moqtaderi Z, Lefrançois P, Struhl K, Gerstein M, Snyder M. Mapping accessible chromatin regions using Sono-Seq. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):14926-31. PMID: 19706456; PMCID: PMC2736440.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  58. Zhang Y, Moqtaderi Z, Rattner BP, Euskirchen G, Snyder M, Kadonaga JT, Liu XS, Struhl K. Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo. Nat Struct Mol Biol. 2009 Aug; 16(8):847-52. PMID: 19620965; PMCID: PMC2823114.
    Citations: 177     Fields:    Translation:AnimalsCells
  59. Fan X, Struhl K. Where does mediator bind in vivo? PLoS One. 2009; 4(4):e5029. PMID: 19343176; PMCID: PMC2661142.
    Citations: 38     Fields:    Translation:AnimalsCells
  60. Madhani HD, Francis NJ, Kingston RE, Kornberg RD, Moazed D, Narlikar GJ, Panning B, Struhl K. Epigenomics: a roadmap, but to where? Science. 2008 Oct 03; 322(5898):43-4. PMID: 18832628; PMCID: PMC4479142.
    Citations: 14     Fields:    Translation:Cells
  61. Miotto B, Struhl K. HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1. Genes Dev. 2008 Oct 01; 22(19):2633-8. PMID: 18832067; PMCID: PMC2559906.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  62. Struhl K. The hisB463 mutation and expression of a eukaryotic protein in Escherichia coli. Genetics. 2008 Oct; 180(2):709-14. PMID: 18927256; PMCID: PMC2567374.
    Citations: 1     Fields:    Translation:Cells
  63. Fan X, Lamarre-Vincent N, Wang Q, Struhl K. Extensive chromatin fragmentation improves enrichment of protein binding sites in chromatin immunoprecipitation experiments. Nucleic Acids Res. 2008 Nov; 36(19):e125. PMID: 18765474; PMCID: PMC2577354.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  64. Thakur JK, Arthanari H, Yang F, Pan SJ, Fan X, Breger J, Frueh DP, Gulshan K, Li DK, Mylonakis E, Struhl K, Moye-Rowley WS, Cormack BP, Wagner G, Näär AM. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature. 2008 Apr 03; 452(7187):604-9. PMID: 18385733.
    Citations: 112     Fields:    Translation:AnimalsCells
  65. Moqtaderi Z, Struhl K. Expanding the repertoire of plasmids for PCR-mediated epitope tagging in yeast. Yeast. 2008 Apr; 25(4):287-92. PMID: 18338317.
    Citations: 14     Fields:    Translation:AnimalsCells
  66. Wade JT, Struhl K. The transition from transcriptional initiation to elongation. Curr Opin Genet Dev. 2008 Apr; 18(2):130-6. PMID: 18282700; PMCID: PMC2563432.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  67. Johnson DS, Li W, Gordon DB, Bhattacharjee A, Curry B, Ghosh J, Brizuela L, Carroll JS, Brown M, Flicek P, Koch CM, Dunham I, Bieda M, Xu X, Farnham PJ, Kapranov P, Nix DA, Gingeras TR, Zhang X, Holster H, Jiang N, Green RD, Song JS, McCuine SA, Anton E, Nguyen L, Trinklein ND, Ye Z, Ching K, Hawkins D, Ren B, Scacheri PC, Rozowsky J, Karpikov A, Euskirchen G, Weissman S, Gerstein M, Snyder M, Yang A, Moqtaderi Z, Hirsch H, Shulha HP, Fu Y, Weng Z, Struhl K, Myers RM, Lieb JD, Liu XS. Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res. 2008 Mar; 18(3):393-403. PMID: 18258921; PMCID: PMC2259103.
    Citations: 73     Fields:    Translation:HumansCells
  68. Struhl K. Kevin Struhl. Interview. Curr Biol. 2008 Jan 08; 18(1):R7-9. PMID: 18228638.
    Citations:    Fields:    
  69. Ghosh S, Hirsch HA, Sekinger EA, Kapranov P, Struhl K, Gingeras TR. Differential analysis for high density tiling microarray data. BMC Bioinformatics. 2007 Sep 24; 8:359. PMID: 17892592; PMCID: PMC2231405.
    Citations: 3     Fields:    Translation:HumansCells
  70. Schwabish MA, Struhl K. The Swi/Snf complex is important for histone eviction during transcriptional activation and RNA polymerase II elongation in vivo. Mol Cell Biol. 2007 Oct; 27(20):6987-95. PMID: 17709398; PMCID: PMC2168902.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  71. Miotto B, Struhl K. [Histone H4 lysine 16 acetylation: from genome regulation to tumoral progression]. Med Sci (Paris). 2007 Aug-Sep; 23(8-9):735-40. PMID: 17875292.
    Citations: 1     Fields:    Translation:HumansCells
  72. Peckham HE, Thurman RE, Fu Y, Stamatoyannopoulos JA, Noble WS, Struhl K, Weng Z. Nucleosome positioning signals in genomic DNA. Genome Res. 2007 Aug; 17(8):1170-7. PMID: 17620451; PMCID: PMC1933512.
    Citations: 145     Fields:    Translation:AnimalsCells
  73. Wade JT, Struhl K, Busby SJ, Grainger DC. Genomic analysis of protein-DNA interactions in bacteria: insights into transcription and chromosome organization. Mol Microbiol. 2007 Jul; 65(1):21-6. PMID: 17581117.
    Citations: 39     Fields:    Translation:Cells
  74. Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith