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Ali Azarbarzin, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 1R01HL153874 (Ali Azarbarzin) Aug 1, 2020 - Jul 31, 2025
    NIH/NHLBI
    Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea
    Role: PI
  2. 19CDA34660137 (Ali Azarbarzin) Apr 1, 2019 - Mar 31, 2022
    American Heart Association
    Phenotyping hypoxia and arousal contributions to cardiovascular morbidity and mortality in patients with sleep apnea.
    Role: PI
  3. 1R21HL145492-01 (Shaun Purcell) Apr 1, 2019 - Mar 31, 2021
    NIH/NHLBI
    Sleep Physiology Dynamics: Quantification, Characterization and Genetic Dissection
    Role: Co-Investigator
  4. 188-SR-17 (Ali Azarbarzin-Susan Redline) Aug 1, 2018 - Jul 31, 2020
    American Academy of Sleep Medicine Foundation
    Identification of optimal, evidence-based definitions of apnea and hypopnea leveraging the National Sleep Research Resource.
    Role: PI
  5. 5R35HL135818-03 (Susan Redline) Jan 1, 2017 - Dec 31, 2023
    NIH/NHLBI
    Phenotypic and Molecular Signatures for Sleep Apnea and Sleep Apnea-Associated Cardiometabolic and Cognitive Outcomes
    Role: Co-Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Borker PV, Reid M, Sofer T, Butler MP, Azarbarzin A, Wang H, Wellman A, Sands SA, Redline S. Non-REM Apnea and Hypopnea Duration Varies across Population Groups and Physiologic Traits. Am J Respir Crit Care Med. 2021 May 01; 203(9):1173-1182. PMID: 33285084.
    Citations:    Fields:    
  2. Azarbarzin A, Wellman A, Redline S, Sands S. Reply to Sankari and to Kawada. Am J Respir Crit Care Med. 2021 Apr 29. PMID: 33915061.
    Citations:    Fields:    
  3. Kwon Y, Wiles C, Parker BE, Clark BR, Sohn MW, Mariani S, Hahn JO, Jacobs DR, Stein JH, Lima J, Kapur V, Wellman A, Redline S, Azarbarzin A. Pulse arrival time, a novel sleep cardiovascular marker: the multi-ethnic study of atherosclerosis. Thorax. 2021 Apr 16. PMID: 33863828.
    Citations:    Fields:    
  4. Op de Beeck S, Dieltjens M, Azarbarzin A, Willemen M, Verbraecken J, Braem MJ, Wellman A, Sands SA, Vanderveken OM. Mandibular Advancement Device Treatment Efficacy Is Associated with Polysomnographic Endotypes. Ann Am Thorac Soc. 2021 03; 18(3):511-518. PMID: 32946702.
    Citations: 1     Fields:    
  5. Azarbarzin A, White DP. Reply to "Impact of obstructive sleep apnea on left ventricular mass index in men with coronary artery disease". J Clin Sleep Med. 2021 Feb 01; 17(2):357. PMID: 33141010.
    Citations: 1     Fields:    
  6. Taranto-Montemurro L, Sands S, Azarbarzin A, Calianese N, Vena D, Hess L, Kim SW, White DP, Wellman A. Impact of cold and flu medication on obstructive sleep apnoea and its underlying traits: A pilot randomized controlled trial. Respirology. 2021 May; 26(5):485-492. PMID: 33491327.
    Citations:    Fields:    
  7. Azarbarzin A, Sands SA, Younes M, Taranto-Montemurro L, Sofer T, Vena D, Alex RM, Kim SW, Gottlieb DJ, White DP, Redline S, Wellman A. The Sleep Apnea-specific Pulse Rate Response Predicts Cardiovascular Morbidity and Mortality. Am J Respir Crit Care Med. 2021 Jan 06. PMID: 33406013.
    Citations: 1     Fields:    
  8. Jackson CL, Umesi C, Gaston SA, Azarbarzin A, Lunyera J, McGrath JA, Jackson Ii WB, Diamantidis CJ, Boulware E, Lutsey PL, Redline S. Multiple, objectively measured sleep dimensions including hypoxic burden and chronic kidney disease: findings from the Multi-Ethnic Study of Atherosclerosis. Thorax. 2020 Dec 04. PMID: 33277428.
    Citations:    Fields:    
  9. Kwon Y, Sands SA, Stone KL, Taranto-Montemurro L, Alex RM, White DP, Wellman A, Redline S, Azarbarzin A. Prolonged Circulation Time Is Associated With Mortality Among Older Men With Sleep-Disordered Breathing. Chest. 2020 Oct 16. PMID: 33069723.
    Citations:    Fields:    
  10. Messineo L, Eckert DJ, Lim R, Chiang A, Azarbarzin A, Carter SG, Carberry JC. Zolpidem increases sleep efficiency and the respiratory arousal threshold without changing sleep apnoea severity and pharyngeal muscle activity. J Physiol. 2020 10; 598(20):4681-4692. PMID: 32864734.
    Citations: 1     Fields:    Translation:Humans
  11. Vena D, Azarbarzin A, Marques M, Op de Beeck S, Vanderveken OM, Edwards BA, Calianese N, Hess LB, Radmand R, Hamilton GS, Joosten SA, Taranto-Montemurro L, Kim SW, Verbraecken J, Braem M, White DP, Sands SA, Wellman A. Predicting sleep apnea responses to oral appliance therapy using polysomnographic airflow. Sleep. 2020 07 13; 43(7). PMID: 32043131.
    Citations: 2     Fields:    Translation:Humans
  12. Kwon Y, Mariani S, Gadi SR, Jacobs DR, Punjabi NM, Reid ML, Azarbarzin A, Wellman AD, Redline S. Characterization of lung-to-finger circulation time in sleep study assessment: the Multi-Ethnic Study of Atherosclerosis. Physiol Meas. 2020 06 30; 41(6):065004. PMID: 32344384.
    Citations: 1     Fields:    
  13. Azarbarzin A, Younes M, Sands SA, Wellman A, Redline S, Czeisler CA, Gottlieb DJ. Interhemispheric sleep depth coherence predicts driving safety in sleep apnea. J Sleep Res. 2021 Apr; 30(2):e13092. PMID: 32441843.
    Citations:    Fields:    
  14. Won CHJ, Reid M, Sofer T, Azarbarzin A, Purcell S, White D, Wellman A, Sands S, Redline S. Sex differences in obstructive sleep apnea phenotypes, the multi-ethnic study of atherosclerosis. Sleep. 2020 05 12; 43(5). PMID: 31687772.
    Citations: 7     Fields:    Translation:Humans
  15. Azarbarzin A, Sands SA, Taranto-Montemurro L, Vena D, Sofer T, Kim SW, Stone KL, White DP, Wellman A, Redline S. The Sleep Apnea-Specific Hypoxic Burden Predicts Incident Heart Failure. Chest. 2020 Aug; 158(2):739-750. PMID: 32298733.
    Citations: 5     Fields:    
  16. Taranto-Montemurro L, Messineo L, Azarbarzin A, Vena D, Hess LB, Calianese NA, White DP, Wellman A, Sands SA. Effects of the Combination of Atomoxetine and Oxybutynin on OSA Endotypic Traits. Chest. 2020 Jun; 157(6):1626-1636. PMID: 32006590.
    Citations: 1     Fields:    
  17. Marques M, Genta PR, Azarbarzin A, Taranto-Montemurro L, Messineo L, Hess LB, Demko G, White DP, Sands SA, Wellman A. Structure and severity of pharyngeal obstruction determine oral appliance efficacy in sleep apnoea. J Physiol. 2019 11; 597(22):5399-5410. PMID: 31503323.
    Citations: 5     Fields:    Translation:Humans
  18. Azarbarzin A, Sands SA, Taranto-Montemurro L, Redline S, Wellman A. Hypoxic burden captures sleep apnoea-specific nocturnal hypoxaemia. Eur Heart J. 2019 09 14; 40(35):2989-2990. PMID: 31071210.
    Citations: 1     Fields:    Translation:Humans
  19. Azarbarzin A, Sands SA, White DP, Redline S, Wellman A. The hypoxic burden: a novel sleep apnoea severity metric and a predictor of cardiovascular mortality-Reply to 'The hypoxic burden: also known as the desaturation severity parameter'. Eur Heart J. 2019 09 14; 40(35):2994-2995. PMID: 31065680.
    Citations: 2     Fields:    Translation:Humans
  20. Kim JS, Azarbarzin A, Wang R, Djonlagic IE, Punjabi NM, Zee PC, Koo BB, Soliman EZ, Younes M, Redline S. Association of novel measures of sleep disturbances with blood pressure: the Multi-Ethnic Study of Atherosclerosis. Thorax. 2020 01; 75(1):57-63. PMID: 31439722.
    Citations: 3     Fields:    Translation:Humans
  21. Mann DL, Terrill PI, Azarbarzin A, Mariani S, Franciosini A, Camassa A, Georgeson T, Marques M, Taranto-Montemurro L, Messineo L, Redline S, Wellman A, Sands SA. Quantifying the magnitude of pharyngeal obstruction during sleep using airflow shape. Eur Respir J. 2019 07; 54(1). PMID: 31000679.
    Citations: 4     Fields:    Translation:Humans
  22. Messineo L, Taranto-Montemurro L, Azarbarzin A, Marques M, Calianese N, White DP, Wellman A, Sands SA. Loop gain in REM versus non-REM sleep using CPAP manipulation: A pilot study. Respirology. 2019 08; 24(8):805-808. PMID: 31212392.
    Citations: 3     Fields:    
  23. Taranto-Montemurro L, Sands SA, Azarbarzin A, Wellman A. Reply to Patel and Althouse: Robust Methods Are Needed to Evaluate the Pharmacologic Treatment of Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2019 05 15; 199(10):1295-1296. PMID: 30807201.
    Citations:    Fields:    Translation:Humans
  24. Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, Eckert DJ, White DP, Wellman A. The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial. Am J Respir Crit Care Med. 2019 05 15; 199(10):1267-1276. PMID: 30395486.
    Citations: 20     Fields:    Translation:Humans
  25. Azarbarzin A, Sands SA, Stone KL, Taranto-Montemurro L, Messineo L, Terrill PI, Ancoli-Israel S, Ensrud K, Purcell S, White DP, Redline S, Wellman A. The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study. Eur Heart J. 2019 04 07; 40(14):1149-1157. PMID: 30376054.
    Citations: 50     Fields:    Translation:Humans
  26. Sands SA, Edwards BA, Terrill PI, Butler JP, Owens RL, Taranto-Montemurro L, Azarbarzin A, Marques M, Hess LB, Smales ET, de Melo CM, White DP, Malhotra A, Wellman A. Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy. Eur Respir J. 2018 09; 52(3). PMID: 30139771.
    Citations: 23     Fields:    Translation:Humans
  27. Taranto-Montemurro L, Sands SA, Grace KP, Azarbarzin A, Messineo L, Salant R, White DP, Wellman DA. Neural memory of the genioglossus muscle during sleep is stage-dependent in healthy subjects and obstructive sleep apnoea patients. J Physiol. 2018 11; 596(21):5163-5173. PMID: 30022493.
    Citations: 3     Fields:    Translation:Humans
  28. Messineo L, Taranto-Montemurro L, Azarbarzin A, Oliveira Marques MD, Calianese N, White DP, Wellman A, Sands SA. Breath-holding as a means to estimate the loop gain contribution to obstructive sleep apnoea. J Physiol. 2018 09; 596(17):4043-4056. PMID: 29882226.
    Citations: 9     Fields:    Translation:Humans
  29. Camassa A, Franciosini A, Sands SA, Zhi YX, Yadollahi A, Bianchi AM, Wellman A, Redline S, Azarbarzin A, Mariani S. Validating an Algorithm for Automatic Scoring of Inspiratory Flow Limitation Within a Range of Recording Settings. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:4788-4791. PMID: 30441417.
    Citations: 1     Translation:Humans
  30. Marques M, Genta PR, Azarbarzin A, Sands SA, Taranto-Montemurro L, Messineo L, White DP, Wellman A. Retropalatal and retroglossal airway compliance in patients with obstructive sleep apnea. Respir Physiol Neurobiol. 2018 12; 258:98-103. PMID: 29913264.
    Citations: 1     Fields:    Translation:Humans
  31. Sands SA, Edwards BA, Terrill PI, Taranto-Montemurro L, Azarbarzin A, Marques M, Hess LB, White DP, Wellman A. Phenotyping Pharyngeal Pathophysiology using Polysomnography in Patients with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2018 05 01; 197(9):1187-1197. PMID: 29327943.
    Citations: 21     Fields:    Translation:Humans
  32. Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A, Bell GI, Below JE, Chun S, Evans DS, Ewert R, Frazier-Wood AC, Gharib SA, Haba-Rubio J, Hagen EW, Heinzer R, Hillman DR, Johnson WC, Kutalik Z, Lane JM, Larkin EK, Lee SK, Liang J, Loredo JS, Mukherjee S, Palmer LJ, Papanicolaou GJ, Penzel T, Peppard PE, Post WS, Ramos AR, Rice K, Rotter JI, Sands SA, Shah NA, Shin C, Stone KL, Stubbe B, Sul JH, Tafti M, Taylor KD, Teumer A, Thornton TA, Tranah GJ, Wang C, Wang H, Warby SC, Wellman DA, Zee PC, Hanis CL, Laurie CC, Gottlieb DJ, Patel SR, Zhu X, Sunyaev SR, Saxena R, Lin X, Redline S. Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men. Am J Respir Cell Mol Biol. 2018 03; 58(3):391-401. PMID: 29077507.
    Citations: 13     Fields:    Translation:Humans
  33. Azarbarzin A, Sands SA, Marques M, Genta PR, Taranto-Montemurro L, Messineo L, White DP, Wellman A. Palatal prolapse as a signature of expiratory flow limitation and inspiratory palatal collapse in patients with obstructive sleep apnoea. Eur Respir J. 2018 02; 51(2). PMID: 29444914.
    Citations: 7     Fields:    Translation:Humans
  34. Sands SA, Terrill PI, Edwards BA, Taranto Montemurro L, Azarbarzin A, Marques M, de Melo CM, Loring SH, Butler JP, White DP, Wellman A. Quantifying the Arousal Threshold Using Polysomnography in Obstructive Sleep Apnea. Sleep. 2018 01 01; 41(1). PMID: 29228393.
    Citations: 24     Fields:    Translation:Humans
  35. de Melo CM, Taranto-Montemurro L, Butler JP, White DP, Loring SH, Azarbarzin A, Marques M, Berger PJ, Wellman A, Sands SA. Stable Breathing in Patients With Obstructive Sleep Apnea Is Associated With Increased Effort but Not Lowered Metabolic Rate. Sleep. 2017 10 01; 40(10). PMID: 28977669.
    Citations: 2     Fields:    Translation:Humans
  36. Azarbarzin A, Marques M, Sands SA, Op de Beeck S, Genta PR, Taranto-Montemurro L, de Melo CM, Messineo L, Vanderveken OM, White DP, Wellman A. Predicting epiglottic collapse in patients with obstructive sleep apnoea. Eur Respir J. 2017 09; 50(3). PMID: 28931660.
    Citations: 14     Fields:    Translation:Humans
  37. Taranto-Montemurro L, Sands SA, Azarbarzin A, Marques M, de Melo CM, Edwards BA, Eckert DJ, Messineo L, White DP, Wellman A. Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults. Ann Am Thorac Soc. 2017 Jul; 14(7):1177-1183. PMID: 28387543.
    Citations: 5     Fields:    Translation:Humans
  38. Gao X, Azarbarzin A, Keenan BT, Ostrowski M, Pack FM, Staley B, Maislin G, Pack AI, Younes M, Kuna ST. Heritability of Heart Rate Response to Arousals in Twins. Sleep. 2017 06 01; 40(6). PMID: 28431171.
    Citations: 5     Fields:    Translation:Humans
  39. Marques M, Genta PR, Sands SA, Azarbazin A, de Melo C, Taranto-Montemurro L, White DP, Wellman A. Effect of Sleeping Position on Upper Airway Patency in Obstructive Sleep Apnea Is Determined by the Pharyngeal Structure Causing Collapse. Sleep. 2017 03 01; 40(3). PMID: 28329099.
    Citations: 6     Fields:    Translation:Humans
  40. Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A. Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients With Obstructive Sleep Apnea. Sleep. 2017 Feb 01; 40(2). PMID: 28364504.
    Citations: 3     Fields:    Translation:Humans
  41. Azarbarzin A, Sands SA, Taranto-Montemurro L, Oliveira Marques MD, Genta PR, Edwards BA, Butler J, White DP, Wellman A. Estimation of Pharyngeal Collapsibility During Sleep by Peak Inspiratory Airflow. Sleep. 2017 Jan 01; 40(1). PMID: 28364460.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  42. Amatoury J, Azarbarzin A, Younes M, Jordan AS, Wellman A, Eckert DJ. Arousal Intensity is a Distinct Pathophysiological Trait in Obstructive Sleep Apnea. Sleep. 2016 Dec 01; 39(12):2091-2100. PMID: 27784404.
    Citations: 19     Fields:    Translation:Humans
  43. Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A. Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients with Obstructive Sleep Apnea. Sleep. 2016 Nov 28. PMID: 27923429.
    Citations:    
  44. Taranto-Montemurro L, Sands SA, Edwards BA, Azarbarzin A, Marques M, de Melo C, Eckert DJ, White DP, Wellman A. Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation. Eur Respir J. 2016 11; 48(5):1340-1350. PMID: 27799387.
    Citations: 24     Fields:    Translation:HumansCells
  45. Azarbarzin A, Sands SA, Taranto-Montemurro L, Oliveira Marques MD, Genta PR, Edwards BA, Butler J, White DP, Wellman A. Estimation of pharyngeal collapsibility during sleep by peak inspiratory airflow. Sleep. 2016 Sep 09. PMID: 27634788.
    Citations:    
  46. Azarbarzin A, Ostrowski M, Younes M, Keenan BT, Pack AI, Staley B, Kuna ST. Arousal Responses during Overnight Polysomnography and their Reproducibility in Healthy Young Adults. Sleep. 2015 Aug 01; 38(8):1313-21. PMID: 25581917.
    Citations: 8     Fields:    Translation:Humans
  47. Azarbarzin A, Ostrowski M, Hanly P, Younes M. Relationship between arousal intensity and heart rate response to arousal. Sleep. 2014 Apr 01; 37(4):645-53. PMID: 24899756.
    Citations: 31     Fields:    Translation:Humans
  48. Azarbarzin A, Ostrowski M, Moussavi Z, Hanly P, Younes M. Contribution of arousal from sleep to postevent tachycardia in patients with obstructive sleep apnea. Sleep. 2013 Jun 01; 36(6):881-9. PMID: 23729931.
    Citations: 7     Fields:    Translation:Humans
  49. MacGregor CA, Karimi D, Azarbarzin A, Moussavi Z. Statistical analysis of tracheal breath sounds during wakefulness for screening obstructive sleep apnea. Annu Int Conf IEEE Eng Med Biol Soc. 2013; 2013:4549-52. PMID: 24110746.
    Citations:    Translation:Humans
  50. Azarbarzin A, Moussavi Z. Intra-subject variability of snoring sounds in relation to body position, sleep stage, and blood oxygen level. Med Biol Eng Comput. 2013 Apr; 51(4):429-39. PMID: 23269579.
    Citations: 5     Fields:    Translation:Humans
  51. Yadollahi A, Montazeri A, Azarbarzin A, Moussavi Z. Respiratory flow-sound relationship during both wakefulness and sleep and its variation in relation to sleep apnea. Ann Biomed Eng. 2013 Mar; 41(3):537-46. PMID: 23149903.
    Citations: 5     Fields:    Translation:Humans
  52. Azarbarzin A, Moussavi Z. Snoring sounds variability as a signature of obstructive sleep apnea. Med Eng Phys. 2013 Apr; 35(4):479-85. PMID: 22824726.
    Citations: 15     Fields:    Translation:Humans
  53. Yadollahi A, Azarbarzin A, Montazeri A, Moussavi Z. Acoustical flow estimation in patients with obstructive sleep apnea during sleep. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:3640-3. PMID: 23366716.
    Citations: 2     Translation:Humans
  54. Azarbarzin A, Moussavi Z. A comparison between recording sites of snoring sounds in relation to upper airway obstruction. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:4246-9. PMID: 23366865.
    Citations: 2     Translation:Humans
  55. Azarbarzin A, Moussavi Z. Do anthropometric parameters change the characteristics of snoring sound? Annu Int Conf IEEE Eng Med Biol Soc. 2011; 2011:1749-52. PMID: 22254665.
    Citations:    Translation:Humans
  56. Azarbarzin A, Moussavi ZM. Automatic and unsupervised snore sound extraction from respiratory sound signals. IEEE Trans Biomed Eng. 2011 May; 58(5):1156-62. PMID: 20679022.
    Citations: 8     Fields:    Translation:Humans
  57. Azarbarzin A, Moussavi Z. Unsupervised classification of respiratory sound signal into snore/no-snore classes. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:3666-9. PMID: 21097044.
    Citations:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.