Harvard Catalyst Profiles

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Andrea Clocchiatti, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Goruppi S, Clocchiatti A, Bottoni G, Di Cicco E, Ma M, Tassone B, Neel V, Demehri S, Simon C, Paolo Dotto G. The ULK3 kinase is a determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome. Nat Commun. 2023 02 16; 14(1):887. PMID: 36797248; PMCID: PMC9935893.
    Citations:    Fields:    Translation:HumansCells
  2. Ma M, Ghosh S, Tavernari D, Katarkar A, Clocchiatti A, Mazzeo L, Samarkina A, Epiney J, Yu YR, Ho PC, Levesque MP, Özdemir BC, Ciriello G, Dummer R, Dotto GP. Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis. J Exp Med. 2021 02 01; 218(2). PMID: 33112375.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  3. Katarkar A, Bottoni G, Clocchiatti A, Goruppi S, Bordignon P, Lazzaroni F, Gregnanin I, Ostano P, Neel V, Dotto GP. NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin. Nat Commun. 2020 10 12; 11(1):5126. PMID: 33046701.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  4. Bottoni G, Katarkar A, Tassone B, Ghosh S, Clocchiatti A, Goruppi S, Bordignon P, Jafari P, Tordini F, Lunardi T, Hoetzenecker W, Neel V, Lingner J, Paolo Dotto G. CSL controls telomere maintenance and genome stability in human dermal fibroblasts. Nat Commun. 2019 08 29; 10(1):3884. PMID: 31467287.
    Citations: 6     Fields:    Translation:HumansCells
  5. Goruppi S, Clocchiatti A, Dotto GP. A role for stromal autophagy in cancer-associated fibroblast activation. Autophagy. 2019 04; 15(4):738-739. PMID: 30653445.
    Citations: 8     Fields:    Translation:HumansCells
  6. Clocchiatti A, Ghosh S, Procopio MG, Mazzeo L, Bordignon P, Ostano P, Goruppi S, Bottoni G, Katarkar A, Levesque M, Kölblinger P, Dummer R, Neel V, Özdemir BC, Dotto GP. Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation. J Clin Invest. 2018 12 03; 128(12):5531-5548. PMID: 30395538; PMCID: PMC6264730.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  7. Goruppi S, Jo SH, Laszlo C, Clocchiatti A, Neel V, Dotto GP. Autophagy Controls CSL/RBPJ? Stability through a p62/SQSTM1-Dependent Mechanism. Cell Rep. 2018 09 18; 24(12):3108-3114.e4. PMID: 30231994.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  8. Goruppi S, Procopio MG, Jo S, Clocchiatti A, Neel V, Dotto GP. The ULK3 Kinase Is Critical for Convergent Control of Cancer-Associated Fibroblast Activation by CSL and GLI. Cell Rep. 2017 Sep 05; 20(10):2468-2479. PMID: 28877478; PMCID: PMC5616185.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  9. Jo SH, Kim DE, Clocchiatti A, Dotto GP. PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation. Oncotarget. 2016 Sep 13; 7(37):58717-58727. PMID: 27542230.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  10. Clocchiatti A, Cora E, Zhang Y, Dotto GP. Sexual dimorphism in cancer. Nat Rev Cancer. 2016 05; 16(5):330-9. PMID: 27079803.
    Citations: 116     Fields:    Translation:HumansCells
  11. Clocchiatti A, Di Giorgio E, Viviani G, Streuli C, Sgorbissa A, Picco R, Cutano V, Brancolini C. The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro. J Cell Sci. 2015 Nov 01; 128(21):3961-76. PMID: 26403201.
    Citations: 14     Fields:    Translation:HumansCells
  12. Di Giorgio E, Gagliostro E, Clocchiatti A, Brancolini C. The control operated by the cell cycle machinery on MEF2 stability contributes to the downregulation of CDKN1A and entry into S phase. Mol Cell Biol. 2015 May; 35(9):1633-47. PMID: 25733682; PMCID: PMC4387215.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  13. Di Giorgio E, Clocchiatti A, Piccinin S, Sgorbissa A, Viviani G, Peruzzo P, Romeo S, Rossi S, Dei Tos AP, Maestro R, Brancolini C. MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation. Mol Cell Biol. 2013 Nov; 33(22):4473-91. PMID: 24043307.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  14. Clocchiatti A, Di Giorgio E, Ingrao S, Meyer-Almes FJ, Tripodo C, Brancolini C. Class IIa HDACs repressive activities on MEF2-depedent transcription are associated with poor prognosis of ER? breast tumors. FASEB J. 2013 Mar; 27(3):942-54. PMID: 23159930.
    Citations: 22     Fields:    Translation:HumansCells
  15. Clocchiatti A, Di Giorgio E, Demarchi F, Brancolini C. Beside the MEF2 axis: unconventional functions of HDAC4. Cell Signal. 2013 Jan; 25(1):269-76. PMID: 23063464.
    Citations: 15     Fields:    Translation:HumansCells
  16. Clocchiatti A, Florean C, Brancolini C. Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis. J Cell Mol Med. 2011 Sep; 15(9):1833-46. PMID: 21435179.
    Citations: 41     Fields:    Translation:HumansAnimals
  17. Cernotta N, Clocchiatti A, Florean C, Brancolini C. Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility. Mol Biol Cell. 2011 Jan 15; 22(2):278-89. PMID: 21118993.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.