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Last Name

profileConor L Evans, Ph.D.

TitleAssistant Professor of Dermatology
InstitutionMassachusetts General Hospital
AddressMassachusetts General Hospital
Dermatology/Bartlett 410
40 Blossom St
Boston MA 02114
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R21CA155535     (EVANS, CONOR LEE)Sep 1, 2011 - Aug 31, 2014
Hyperspectral and Structural Microscopy Platform for Therapy of Resistant Cancer
Role: Principal Investigator

DP2OD007096     (EVANS, CONOR LEE)Sep 30, 2010 - Jun 30, 2015
Imaging and Overcoming Hypoxia-Induced Resistance in Metastatic Ovarian Cancer
Role: Principal Investigator

F32CA138153     (EVANS, CONOR LEE)Apr 1, 2009 - Mar 31, 2012
Multimodality Microendoscope for Metastatic Ovarian Cancer Detection &Treatment
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Klein OJ, Yuan H, Nowell NH, Kaittanis C, Josephson L, Evans CL. An Integrin-Targeted, Highly Diffusive Construct for Photodynamic Therapy. Sci Rep. 2017 Oct 17; 7(1):13375. PMID: 29042620.
    View in: PubMed
  2. Li Z, Navarro-Alvarez N, Keeley EJ, Nowell NH, Goncalves BMM, Huang CA, Evans CL. Non-invasive monitoring of skin inflammation using an oxygen-sensing paint-on bandage. Biomed Opt Express. 2017 Oct 01; 8(10):4640-4651. PMID: 29082091.
    View in: PubMed
  3. Koolen PGL, Li Z, Roussakis E, Paul MA, Ibrahim AMS, Matyal R, Huang T, Evans CL, Lin SJ. Oxygen-Sensing Paint-On Bandage: Calibration of a Novel Approach in Tissue Perfusion Assessment. Plast Reconstr Surg. 2017 Jul; 140(1):89-96. PMID: 28654595.
    View in: PubMed
  4. Bazou D, Maimon N, Gruionu G, Grahovac J, Seano G, Liu H, Evans CL, Munn LL. Vascular beds maintain pancreatic tumour explants for ex vivo drug screening. J Tissue Eng Regen Med. 2017 Jun 01. PMID: 28568605.
    View in: PubMed
  5. Evans CL. New near-infrared dyes light up deep tissue imaging. Sci Transl Med. 2017 Feb 22; 9(378). PMID: 28228597.
    View in: PubMed
  6. Evans CL. Endomicroscope sheds light on cervical tissue. Sci Transl Med. 2017 Jan 11; 9(372). PMID: 28077680.
    View in: PubMed
  7. Apiou-Sbirlea G, Evans CL, Kelly KM, Tromberg BJ. Special Section Guest Editorial: Translational biophotonics. J Biomed Opt. 2016 Dec 01; 21(12):124002. PMID: 27999859.
    View in: PubMed
  8. Wang H, Osseiran S, Igras V, Nichols AJ, Roider EM, Pruessner J, Tsao H, Fisher DE, Evans CL. In vivo coherent Raman imaging of the melanomagenesis-associated pigment pheomelanin. Sci Rep. 2016 Nov 28; 6:37986. PMID: 27892516.
    View in: PubMed
  9. Evans CL. Photoacoustic imaging sounds the alarm on liver fibrosis. Sci Transl Med. 2016 Nov 23; 8(366):366ec186. PMID: 27881817.
    View in: PubMed
  10. Hung HI, Klein OJ, Peterson SW, Rokosh SR, Osseiran S, Nowell NH, Evans CL. PLGA nanoparticle encapsulation reduces toxicity while retaining the therapeutic efficacy of EtNBS-PDT in vitro. Sci Rep. 2016 Sep 30; 6:33234. PMID: 27686626.
    View in: PubMed
  11. Saytashev I, Glenn R, Murashova GA, Osseiran S, Spence D, Evans CL, Dantus M. Multiphoton excited hemoglobin fluorescence and third harmonic generation for non-invasive microscopy of stored blood. Biomed Opt Express. 2016 Sep 01; 7(9):3449-3460. PMID: 27699111.
    View in: PubMed
  12. Jung Y, Klein OJ, Wang H, Evans CL. Longitudinal, label-free, quantitative tracking of cell death and viability in a 3D tumor model with OCT. Sci Rep. 2016 Jun 01; 6:27017. PMID: 27248849; PMCID: PMC4888651.
  13. Kessel D, Evans CL. Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy. Photochem Photobiol. 2016 07; 92(4):620-3. PMID: 27096545; PMCID: PMC4961560 [Available on 07/01/17].
  14. Austin LA, Osseiran S, Evans CL. Raman technologies in cancer diagnostics. Analyst. 2016 Jan 21; 141(2):476-503. PMID: 26539569.
    View in: PubMed
  15. Roussakis E, Li Z, Nowell NH, Nichols AJ, Evans CL. Bright, "Clickable" Porphyrins for the Visualization of Oxygenation under Ambient Light. Angew Chem Int Ed Engl. 2015 Dec 01; 54(49):14728-31. PMID: 26510549; PMCID: PMC4715754 [Available on 12/01/16].
  16. Roussakis E, Li Z, Nichols AJ, Evans CL. Oxygen-Sensing Methods in Biomedicine from the Macroscale to the Microscale. Angew Chem Int Ed Engl. 2015 Jul 13; 54(29):8340-62. PMID: 26084034.
    View in: PubMed
  17. Ray Jalian H, Tam J, Vuong LN, Fisher J, Garibyan L, Mihm MC, Zurakowski D, Evans CL, Rox Anderson R. Selective Cryolysis of Sebaceous Glands. J Invest Dermatol. 2015 Sep; 135(9):2173-2180. PMID: 25860384.
    View in: PubMed
  18. Rowlands CJ, Wu J, Uzel SG, Klein O, Evans CL, So PT. 3D-resolved targeting of photodynamic therapy using temporal focusing. Laser Phys Lett. 2014 Nov; 11(11). PMID: 25620902.
    View in: PubMed
  19. Evans CL. Peering under the skin: measuring melanoma depth with ultrasound and optical coherence tomography. Br J Dermatol. 2014 Oct; 171(4):690-1. PMID: 25319422.
    View in: PubMed
  20. Li Z, Roussakis E, Koolen PG, Ibrahim AM, Kim K, Rose LF, Wu J, Nichols AJ, Baek Y, Birngruber R, Apiou-Sbirlea G, Matyal R, Huang T, Chan R, Lin SJ, Evans CL. Non-invasive transdermal two-dimensional mapping of cutaneous oxygenation with a rapid-drying liquid bandage. Biomed Opt Express. 2014 Nov 01; 5(11):3748-64. PMID: 25426308; PMCID: PMC4242015.
  21. Jung Y, Tam J, Ray Jalian H, Rox Anderson R, Evans CL. Longitudinal, 3D in vivo imaging of sebaceous glands by coherent anti-stokes Raman scattering microscopy: normal function and response to cryotherapy. J Invest Dermatol. 2015 Jan; 135(1):39-44. PMID: 25026458; PMCID: PMC4268001.
  22. Jung Y, Ng JH, Keating CP, Senthil-Kumar P, Zhao J, Randolph MA, Winograd JM, Evans CL. Comprehensive evaluation of peripheral nerve regeneration in the acute healing phase using tissue clearing and optical microscopy in a rodent model. PLoS One. 2014; 9(4):e94054. PMID: 24714405; PMCID: PMC3979924.
  23. Nichols AJ, Roussakis E, Klein OJ, Evans CL. Click-assembled, oxygen-sensing nanoconjugates for depth-resolved, near-infrared imaging in a 3D cancer model. Angew Chem Int Ed Engl. 2014 Apr 01; 53(14):3671-4. PMID: 24590700; PMCID: PMC4026265.
  24. Vecchio D, Bhayana B, Huang L, Carrasco E, Evans CL, Hamblin MR. Structure-function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers. Eur J Med Chem. 2014 Mar 21; 75:479-491. PMID: 24561676; PMCID: PMC3970436.
  25. Klein OJ, Bhayana B, Park YJ, Evans CL. In vitro optimization of EtNBS-PDT against hypoxic tumor environments with a tiered, high-content, 3D model optical screening platform. Mol Pharm. 2012 Nov 05; 9(11):3171-82. PMID: 22946843; PMCID: PMC3538815.
  26. Jung Y, Nichols AJ, Klein OJ, Roussakis E, Evans CL. Label-Free, Longitudinal Visualization of PDT Response In Vitro with Optical Coherence Tomography. Isr J Chem. 2012 Sep; 52(8-9):728-744. PMID: 23316088.
    View in: PubMed
  27. de Groot M, Evans CL, de Boer JF. Self-interference fluorescence microscopy: three dimensional fluorescence imaging without depth scanning. Opt Express. 2012 Jul 02; 20(14):15253-62. PMID: 22772223; PMCID: PMC3601652.
  28. Nichols AJ, Evans CL. Video-rate scanning confocal microscopy and microendoscopy. J Vis Exp. 2011 Oct 20; (56). PMID: 22042305; PMCID: PMC3227211.
  29. Evans CL, Abu-Yousif AO, Park YJ, Klein OJ, Celli JP, Rizvi I, Zheng X, Hasan T. Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT. PLoS One. 2011; 6(8):e23434. PMID: 21876751; PMCID: PMC3158086.
  30. Rizvi I, Celli JP, Evans CL, Abu-Yousif AO, Muzikansky A, Pogue BW, Finkelstein D, Hasan T. Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer. Cancer Res. 2010 Nov 15; 70(22):9319-28. PMID: 21062986; PMCID: PMC3057933.
  31. Celli JP, Rizvi I, Evans CL, Abu-Yousif AO, Hasan T. Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model. J Biomed Opt. 2010 Sep-Oct; 15(5):051603. PMID: 21054077; PMCID: PMC2948043.
  32. Celli JP, Spring BQ, Rizvi I, Evans CL, Samkoe KS, Verma S, Pogue BW, Hasan T. Imaging and photodynamic therapy: mechanisms, monitoring, and optimization. Chem Rev. 2010 May 12; 110(5):2795-838. PMID: 20353192; PMCID: PMC2896821.
  33. Joo C, Evans CL, Stepinac T, Hasan T, de Boer JF. Diffusive and directional intracellular dynamics measured by field-based dynamic light scattering. Opt Express. 2010 Feb 01; 18(3):2858-71. PMID: 20174115; PMCID: PMC2839546.
  34. Abu-Yousif AO, Rizvi I, Evans CL, Celli JP, Hasan T. PuraMatrix encapsulation of cancer cells. J Vis Exp. 2009 Dec 17; (34). PMID: 20019656; PMCID: PMC3152243.
  35. Evans CL, Rizvi I, Hasan T, de Boer JF. In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging. Opt Express. 2009 May 25; 17(11):8892-906. PMID: 19466138; PMCID: PMC2836890.
  36. Zheng X, Sallum UW, Verma S, Athar H, Evans CL, Hasan T. Exploiting a bacterial drug-resistance mechanism: a light-activated construct for the destruction of MRSA. Angew Chem Int Ed Engl. 2009; 48(12):2148-51. PMID: 19206126.
    View in: PubMed
  37. Evans CL, Xie XS. Coherent anti-stokes Raman scattering microscopy: chemical imaging for biology and medicine. Annu Rev Anal Chem (Palo Alto Calif). 2008; 1:883-909. PMID: 20636101.
    View in: PubMed
  38. Evans CL, Xu X, Kesari S, Xie XS, Wong ST, Young GS. Chemically-selective imaging of brain structures with CARS microscopy. Opt Express. 2007 Sep 17; 15(19):12076-87. PMID: 19547572.
    View in: PubMed
  39. Ganikhanov F, Evans CL, Saar BG, Xie XS. High-sensitivity vibrational imaging with frequency modulation coherent anti-Stokes Raman scattering (FM CARS) microscopy. Opt Lett. 2006 Jun 15; 31(12):1872-4. PMID: 16729099.
    View in: PubMed
  40. Légaré F, Evans CL, Ganikhanov F, Xie XS. Towards CARS Endoscopy. Opt Express. 2006 May 15; 14(10):4427-32. PMID: 19516594.
    View in: PubMed
  41. Potma EO, Evans CL, Xie XS. Heterodyne coherent anti-Stokes Raman scattering (CARS) imaging. Opt Lett. 2006 Jan 15; 31(2):241-3. PMID: 16441043.
    View in: PubMed
  42. Rakic B, Sagan SM, Noestheden M, Bélanger S, Nan X, Evans CL, Xie XS, Pezacki JP. Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replication. Chem Biol. 2006 Jan; 13(1):23-30. PMID: 16426968.
    View in: PubMed
  43. Evans CL, Potma EO, Puoris'haag M, Côté D, Lin CP, Xie XS. Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy. Proc Natl Acad Sci U S A. 2005 Nov 15; 102(46):16807-12. PMID: 16263923; PMCID: PMC1283840.
  44. Evans CL, Potma EO, Xie XS. Coherent anti-stokes raman scattering spectral interferometry: determination of the real and imaginary components of nonlinear susceptibility chi(3) for vibrational microscopy. Opt Lett. 2004 Dec 15; 29(24):2923-5. PMID: 15645825.
    View in: PubMed
  45. Potma EO, Evans C, Xie XS, Jones RJ, Ye J. Picosecond-pulse amplification with an external passive optical cavity. Opt Lett. 2003 Oct 01; 28(19):1835-7. PMID: 14514117.
    View in: PubMed
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