Harvard Catalyst Profiles

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Mei-Sing Ong, Ph.D.


Available: 12/01/22, Expires: 10/31/23

Improving representation of racial and ethnic groups in US clinical trials has been a focus of federal initiatives for nearly 3 decades. Equitable representation of racial and ethnic minorities in clinical trials is essential if they are to share the benefits derived from advances in medical science. Yet, racial and ethnic minorities continue to be underrepresented in clinical trials. The goal of this NIH-sponsored project is to investigate the extent to which racial and ethnic minorities are under-represented in pediatric clinical trials, and the potential factors contributing to willingness to participate in clinical trials. The student will work closely with the research team to review clinical trial data to evaluate participation of minority children in clinical trials. No prior experience is required, appropriate training will be provided.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Geier CB, Ellison M, Cruz R, Pawar S, Leiss-Piller A, Zmajkovicova K, McNulty SM, Yilmaz M, Evans MO, Gordon S, Ujhazi B, Wiest I, Abolhassani H, Aghamohammadi A, Barmettler S, Bhar S, Bondarenko A, Bolyard AA, Buchbinder D, Cada M, Cavieres M, Connelly JA, Dale DC, Deordieva E, Dorsey MJ, Drysdale SB, Ehl S, Elfeky R, Fioredda F, Firkin F, Förster-Waldl E, Geng B, Goda V, Gonzalez-Granado L, Grunebaum E, Grzesk E, Henrickson SE, Hilfanova A, Hiwatari M, Imai C, Ip W, Jyonouchi S, Kanegane H, Kawahara Y, Khojah AM, Kim VH, Kojic M, Koltan S, Krivan G, Langguth D, Lau YL, Leung D, Miano M, Mersyanova I, Mousallem T, Muskat M, Naoum FA, Noronha SA, Ouederni M, Ozono S, Richmond GW, Sakovich I, Salzer U, Schuetz C, Seeborg FO, Sharapova SO, Sockel K, Volokha A, von Bonin M, Warnatz K, Wegehaupt O, Weinberg GA, Wong KJ, Worth A, Yu H, Zharankova Y, Zhao X, Devlin L, Badarau A, Csomos K, Keszei M, Pereira J, Taveras AG, Beaussant-Cohen SL, Ong MS, Shcherbina A, Walter JE. Disease Progression of WHIM Syndrome in an International Cohort of 66 Pediatric and Adult Patients. J Clin Immunol. 2022 11; 42(8):1748-1765. PMID: 35947323; PMCID: PMC9700649.
    Citations:    Fields:    Translation:Humans
  2. Ong MS, Rothman D, Barmettler S, Son MB, Lo M, Roberts J, Natter M. New-onset hypogammaglobulinaemia and infectious complications associated with rituximab use in childhood-onset rheumatic diseases. Rheumatology (Oxford). 2022 04 11; 61(4):1610-1620. PMID: 34329428.
    Citations:    Fields:    Translation:Humans
  3. Kimura Y, Ong MS, Tomlinson G, Ringold S, Schanberg LE, Feldman BM, Dennos A, Del Gaizo V, Murphy KL, Natter M. The importance of rigorous methods in observational comparative effectiveness studies of rare diseases: comment on the article by Ruperto et al. Arthritis Rheumatol. 2022 05; 74(5):912-913. PMID: 34905294.
    Citations:    Fields:    Translation:Humans
  4. Kan M, Diwadkar AR, Shuai H, Joo J, Wang AL, Ong MS, Sordillo JE, Iribarren C, Lu MX, Hernandez-Pacheco N, Perez-Garcia J, Gorenjak M, Potocnik U, Burchard EG, Pino-Yanes M, Wu AC, Himes BE. Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene. J Allergy Clin Immunol. 2022 06; 149(6):1981-1991. PMID: 34971648; PMCID: PMC9177524.
    Citations: 1     Fields:    Translation:Humans
  5. Ong MS, Ringold S, Kimura Y, Schanberg LE, Tomlinson GA, Natter MD. Improved Disease Course Associated With Early Initiation of Biologics in Polyarticular Juvenile Idiopathic Arthritis: Trajectory Analysis of a Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans Study. Arthritis Rheumatol. 2021 10; 73(10):1910-1920. PMID: 34105303.
    Citations: 7     Fields:    Translation:Humans
  6. Labrosse R, Barmettler S, Derfalvi B, Blincoe A, Cros G, Lacombe-Barrios J, Barsalou J, Yang N, Alrumayyan N, Sinclair J, Ong MS, Camargo CA, Walter J, Haddad E. Rituximab-induced hypogammaglobulinemia and infection risk in pediatric patients. J Allergy Clin Immunol. 2021 08; 148(2):523-532.e8. PMID: 33862010.
    Citations: 7     Fields:    Translation:Humans
  7. Sharapova SO, Pashchenko OE, Bondarenko AV, Vakhlyarskaya SS, Prokofjeva T, Fedorova AS, Savchak I, Mareika Y, Valiev TT, Popa A, Tuzankina IA, Vlasova EV, Sakovich IS, Polyakova EA, Rumiantseva NV, Naumchik IV, Kulyova SA, Aleshkevich SN, Golovataya EI, Minakovskaya NV, Belevtsev MV, Latysheva EA, Latysheva TV, Beznoshchenko AG, Akopyan H, Makukh H, Kozlova O, Varabyou DS, Ballow M, Ong MS, Walter JE, Kondratenko IV, Kostyuchenko LV, Aleinikova OV. Geographical Distribution, Incidence, Malignancies, and Outcome of 136 Eastern Slavic Patients With Nijmegen Breakage Syndrome and NBN Founder Variant c.657_661del5. Front Immunol. 2020; 11:602482. PMID: 33488600; PMCID: PMC7819964.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  8. Ong MS. Socioeconomic status and survival in patients with pulmonary hypertension. ERJ Open Res. 2020 Oct; 6(4). PMID: 33263067.
    Citations: 1     
  9. Ong MS, Klann JG, Lin KJ, Maron BA, Murphy SN, Natter MD, Mandl KD. Claims-Based Algorithms for Identifying Patients With Pulmonary Hypertension: A Comparison of Decision Rules and Machine-Learning Approaches. J Am Heart Assoc. 2020 10 20; 9(19):e016648. PMID: 32990147.
    Citations: 7     Fields:    Translation:Humans
  10. Macías CG, Wharam JF, Maron BA, Ong MS. Urban-Rural Disparities in Pulmonary Hypertension Mortality. Ann Am Thorac Soc. 2020 09; 17(9):1168-1171. PMID: 32584607.
    Citations: 4     Fields:    Translation:Humans
  11. Ong MS, Lakoma M, Gees Bhosrekar S, Hickok J, McLean L, Murphy M, Poland RE, Purtell N, Ross-Degnan D. Risk factors for suicide attempt in children, adolescents, and young adults hospitalized for mental health disorders. Child Adolesc Ment Health. 2021 05; 26(2):134-142. PMID: 32569425.
    Citations: 6     Fields:    Translation:Humans
  12. Barmettler S, Ong MS, Farmer JR, Yang N, Cobbold M, Walter JE, Long AA, Camargo CA. Gastrointestinal manifestations in common variable immunodeficiency (CVID) are associated with an altered immunophenotype including B- and T-cell dysregulation. J Allergy Clin Immunol Pract. 2020 04; 8(4):1436-1438.e1. PMID: 31704440.
    Citations:    Fields:    Translation:HumansCells
  13. Weitzman ER, Ong MS. Rising Prevalence of Comorbid Alcohol and Opioid Use Disorders in Adolescents and Young Adults in the United States. J Gen Intern Med. 2019 10; 34(10):1987-1989. PMID: 31152359.
    Citations: 1     Fields:    Translation:Humans
  14. Ong MS, Abman S, Austin ED, Feinstein JA, Hopper RK, Krishnan US, Mullen MP, Natter MD, Raj JU, Rosenzweig EB, Mandl KD. Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry. J Pediatr. 2019 08; 211:63-71.e6. PMID: 31176455; PMCID: PMC6776463.
    Citations: 6     Fields:    Translation:Humans
  15. Ong MS. A Bayesian Network Approach to Disease Subtype Discovery. Methods Mol Biol. 2019; 1939:299-322. PMID: 30848469.
    Citations: 1     Fields:    Translation:Humans
  16. Barmettler S, Ong MS, Farmer JR, Choi H, Walter J. Association of Immunoglobulin Levels, Infectious Risk, and Mortality With Rituximab and Hypogammaglobulinemia. JAMA Netw Open. 2018 11 02; 1(7):e184169. PMID: 30646343; PMCID: PMC6324375.
    Citations: 78     Fields:    Translation:HumansAnimalsPHPublic Health
  17. Ong MS, Magrabi F, Coiera E. Delay in reviewing test results prolongs hospital length of stay: a retrospective cohort study. BMC Health Serv Res. 2018 05 16; 18(1):369. PMID: 29769074.
    Citations: 2     Fields:    Translation:Humans
  18. Farmer JR, Ong MS, Barmettler S, Yonker LM, Fuleihan R, Sullivan KE, Cunningham-Rundles C, Walter JE. Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets. Front Immunol. 2017; 8:1740. PMID: 29375540.
    Citations: 29     Fields:    
  19. Ong MS, Mullen MP, Austin ED, Szolovits P, Natter MD, Geva A, Cai T, Kong SW, Mandl KD. Learning a Comorbidity-Driven Taxonomy of Pediatric Pulmonary Hypertension. Circ Res. 2017 Aug 04; 121(4):341-353. PMID: 28611076; PMCID: PMC5559726.
    Citations: 5     Fields:    Translation:Humans
  20. Raichand S, Dunn AG, Ong MS, Bourgeois FT, Coiera E, Mandl KD. Conclusions in systematic reviews of mammography for breast cancer screening and associations with review design and author characteristics. Syst Rev. 2017 05 22; 6(1):105. PMID: 28532422.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  21. Ong MS, Mandl KD. Trends in Prostate-Specific Antigen Screening and Prostate Cancer Interventions 3 Years After the U.S. Preventive Services Task Force Recommendation. Ann Intern Med. 2017 03 21; 166(6):451-452. PMID: 28320011.
    Citations: 4     Fields:    Translation:Humans
  22. Ong MS, Olson KL, Chadwick L, Liu C, Mandl KD. The Impact of Provider Networks on the Co-Prescriptions of Interacting Drugs: A Claims-Based Analysis. Drug Saf. 2017 03; 40(3):263-272. PMID: 28000151.
    Citations: 15     Fields:    Translation:Humans
  23. Ong MS, Grand RJ, Mandl KD. Trends in Pharmacologic Interventions for Preventing Recurrence of Crohn's Disease After Ileocolonic Surgery. Inflamm Bowel Dis. 2016 10; 22(10):2432-41. PMID: 27631599.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  24. Ong MS, Olson KL, Cami A, Liu C, Tian F, Selvam N, Mandl KD. Erratum to: Provider patient-sharing networks and multiple-provider prescribing of benzodiazepines. J Gen Intern Med. 2016 May; 31(5):588. PMID: 26514839.
    Citations: 1     Fields:    
  25. Ramanan V, Trehan K, Ong ML, Luna JM, Hoffmann HH, Espiritu C, Sheahan TP, Chandrasekar H, Schwartz RE, Christine KS, Rice CM, van Oudenaarden A, Bhatia SN. Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies. Virology. 2016 07; 494:236-47. PMID: 27128351; PMCID: PMC5366982.
    Citations: 10     Fields:    Translation:HumansCells
  26. Ong MS, Mandl K. Mammography Risks: The Authors Reply. Health Aff (Millwood). 2016 Mar; 35(3):552. PMID: 26953317.
    Citations:    Fields:    
  27. Magrabi F, Ong MS, Coiera E. Health IT for Patient Safety and Improving the Safety of Health IT. Stud Health Technol Inform. 2016; 222:25-36. PMID: 27198089.
    Citations: 4     Fields:    Translation:Humans
  28. Ong MS, Mandl KD. New Guidelines For Breast Cancer Screening. Health Aff (Millwood). 2016 Jan; 35(1):180. PMID: 26733716.
    Citations:    Fields:    Translation:HumansPHPublic Health
  29. Wang Y, Coiera E, Gallego B, Concha OP, Ong MS, Tsafnat G, Roffe D, Jones G, Magrabi F. Measuring the effects of computer downtime on hospital pathology processes. J Biomed Inform. 2016 Feb; 59:308-15. PMID: 26732996.
    Citations: 6     Fields:    Translation:Humans
  30. Man MY, Ong MS, Mohamad MS, Deris S, Sulong G, Yunus J, Che Harun FK. A Review on the Bioinformatics Tools for Neuroimaging. Malays J Med Sci. 2015 Dec; 22(Spec Issue):9-19. PMID: 27006633; PMCID: PMC4795522.
    Citations: 2     
  31. Ong MS, Olson KL, Cami A, Liu C, Tian F, Selvam N, Mandl KD. Provider Patient-Sharing Networks and Multiple-Provider Prescribing of Benzodiazepines. J Gen Intern Med. 2016 Feb; 31(2):164-171. PMID: 26187583.
    Citations: 22     Fields:    Translation:Humans
  32. Ong MS, Mandl KD. Breast Cancer Diagnoses: The Authors Reply. Health Aff (Millwood). 2015 Jul; 34(7):1253. PMID: 26153323.
    Citations:    Fields:    
  33. Ong MS, Mandl KD. National expenditure for false-positive mammograms and breast cancer overdiagnoses estimated at $4 billion a year. Health Aff (Millwood). 2015 Apr; 34(4):576-83. PMID: 25847639.
    Citations: 28     Fields:    Translation:HumansPHPublic Health
  34. Magrabi F, Baker M, Sinha I, Ong MS, Harrison S, Kidd MR, Runciman WB, Coiera E. Clinical safety of England's national programme for IT: a retrospective analysis of all reported safety events 2005 to 2011. Int J Med Inform. 2015 Mar; 84(3):198-206. PMID: 25617015.
    Citations: 30     Fields:    Translation:Humans
  35. Zhou X, Coiera E, Tsafnat G, Arachi D, Ong MS, Dunn AG. Using social connection information to improve opinion mining: Identifying negative sentiment about HPV vaccines on Twitter. Stud Health Technol Inform. 2015; 216:761-5. PMID: 26262154.
    Citations: 31     Fields:    Translation:PHPublic Health
  36. Ong MS, Kohane IS, Cai T, Gorman MP, Mandl KD. Population-level evidence for an autoimmune etiology of epilepsy. JAMA Neurol. 2014 May; 71(5):569-74. PMID: 24687183; PMCID: PMC4324719.
    Citations: 60     Fields:    Translation:HumansPHPublic Health
  37. Ong MS, Umetsu DT, Mandl KD. Consequences of antibiotics and infections in infancy: bugs, drugs, and wheezing. Ann Allergy Asthma Immunol. 2014 May; 112(5):441-445.e1. PMID: 24631182.
    Citations: 34     Fields:    Translation:Humans
  38. Ong MS, Magrabi F, Post J, Morris S, Westbrook J, Wobcke W, Calcroft R, Coiera E. Communication interventions to improve adherence to infection control precautions: a randomised crossover trial. BMC Infect Dis. 2013 Feb 06; 13:72. PMID: 23388051.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  39. Ong MS, Magrabi F, Coiera E. Syndromic surveillance for health information system failures: a feasibility study. J Am Med Inform Assoc. 2013 May 01; 20(3):506-12. PMID: 23184193.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  40. Ong MS, Magrabi F, Jones G, Coiera E. Let's Just Check That Potassium One More Time . . . : Comment on "Last Orders: Follow-up of Tests Ordered on the Day of Hospital Discharge". Arch Intern Med. 2012 Sep 24; 172(17):1344-53. PMID: 22892945.
    Citations:    Fields:    
  41. Ong MS, Magrabi F, Jones G, Coiera E. Last Orders: Follow-up of Tests Ordered on the Day of Hospital Discharge. Arch Intern Med. 2012 Sep 24; 172(17):1347-9. PMID: 22892677.
    Citations: 4     Fields:    
  42. Ong MS, Magrabi F, Coiera E. Automated identification of extreme-risk events in clinical incident reports. J Am Med Inform Assoc. 2012 Jun; 19(e1):e110-8. PMID: 22237865.
    Citations: 13     Fields:    Translation:Humans
  43. Magrabi F, Ong MS, Runciman W, Coiera E. Patient safety problems associated with heathcare information technology: an analysis of adverse events reported to the US Food and Drug Administration. AMIA Annu Symp Proc. 2011; 2011:853-7. PMID: 22195143.
    Citations: 17     Fields:    Translation:HumansPHPublic Health
  44. Ong MS, Coiera E. Evaluating the effectiveness of clinical alerts: a signal detection approach. AMIA Annu Symp Proc. 2011; 2011:1036-44. PMID: 22195164.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  45. Magrabi F, Ong MS, Runciman W, Coiera E. Using FDA reports to inform a classification for health information technology safety problems. J Am Med Inform Assoc. 2012 Jan-Feb; 19(1):45-53. PMID: 21903979.
    Citations: 63     Fields:    
  46. Ong MS, Coiera E. A systematic review of failures in handoff communication during intrahospital transfers. Jt Comm J Qual Patient Saf. 2011 Jun; 37(6):274-84. PMID: 21706987.
    Citations: 38     Fields:    Translation:Humans
  47. Dunn AG, Ong MS, Westbrook JI, Magrabi F, Coiera E, Wobcke W. A simulation framework for mapping risks in clinical processes: the case of in-patient transfers. J Am Med Inform Assoc. 2011 May 01; 18(3):259-66. PMID: 21486883.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  48. Magrabi F, Ong MS, Runciman W, Coiera E. An analysis of computer-related patient safety incidents to inform the development of a classification. J Am Med Inform Assoc. 2010 Nov-Dec; 17(6):663-70. PMID: 20962128.
    Citations: 47     Fields:    Translation:Humans
  49. Ong MS, Magrabi F, Coiera E. Automated categorisation of clinical incident reports using statistical text classification. Qual Saf Health Care. 2010 Dec; 19(6):e55. PMID: 20724392.
    Citations: 20     Fields:    Translation:Humans
  50. Ong MS, Coiera E. Safety through redundancy: a case study of in-hospital patient transfers. Qual Saf Health Care. 2010 Oct; 19(5):e32. PMID: 20671076.
    Citations: 10     Fields:    Translation:Humans
  51. Holstein JH, Herrmann M, Splett C, Herrmann W, Garcia P, Histing T, Graeber S, Ong MF, Kurz K, Siebel T, Menger MD, Pohlemann T. Low serum folate and vitamin B-6 are associated with an altered cancellous bone structure in humans. Am J Clin Nutr. 2009 Nov; 90(5):1440-5. PMID: 19759168.
    Citations: 11     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.