Harvard Catalyst Profiles

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David Johnson Einstein, M.D.

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Biography
Yale University, New Haven, CTBS05/2007Biology
Tufts University School of Medicine, Boston, MAMD05/2011
Tufts Medical Center, Boston, MA06/2014Internal Medicine Residency
Beth Israel Deaconess Medical Center, Boston, MA06/2017Hematology/Oncology Fellowship

Overview
I am an academic medical oncologist specializing in genitourinary (GU) cancers. I care for patients with prostate, bladder, kidney, and testicular cancer. My clinical activities include providing direct patient care and consultation during three-to-four half-day clinics a week and four weeks a year on the inpatient oncology ward and hematology/oncology consult services, during which time I also teach and supervise residents and fellows. In addition, I spend approximately half of my time on genitourinary oncology research, particularly focusing on immunotherapy and targeted approaches in prostate, bladder, and kidney cancers, with support from the Prostate Cancer Foundation, DoD, BIDMC, and industry partners. I am interested in clinical trial development, serving as overall Principal Investigator (PI) and site PI of several Dana-Farber/Harvard Cancer Center (DF/HCC) clinical trials that investigate immune-based and targeted therapies for GU cancers. In addition, I am the Director of GU Oncology Clinical Research for the Beth Israel-Lahey Health network. I conduct translational research as PI of the DF/HCC GU Rapid Autopsy program, a component of the Pathology core of the DF/HCC Prostate SPORE proposal. I am first author of the American Society of Clinical Oncology Self-Evaluation Program GU chapter 7th edition and ongoing reviewer. Finally, I have developed tools to improve quality of life, physician communication, and end-of-life decision-making, especially as it relates to patients with GU cancers.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P20-CA233255 Developmental Research Project (Steven Balk and David Einstein) Mar 31, 2019 - Mar 31, 2020
    Genomic Features of Immunogenic Prostate Cancer in African-American Patients
    Role: Co-Investigator
  2. Bridge Grant (Steven Balk, David Einstein, & Michael Yaffe) Mar 1, 2019 - Feb 28, 2021
    Bridge Project (Koch Institute for Integrative Cancer Research at MIT and the Dana-Farber/Harvard Cancer Center
    Optimizing Plk1 Therapeutics for Clinical Translation
  3. Challenge Award (Steven Balk) Jan 1, 2019 - Jan 1, 2021
    Prostate Cancer Foundation
    Identifying and Targeting Immunogenic Prostate Cancer at High Risk for Lethal Metastatic Progression
    Role: Co-Investigator
  4. W81XWH-17-1-0350 (David J Einstein) Aug 1, 2017 - Jul 30, 2021
    Congressionally Directed Medical Research Programs (CDMRP) Prostate Cancer Research Program (PCRP)
    Prognostic Biomarkers in Active Surveillance: Parsing Risk in Early-Stage Prostate Cancer

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.