Harvard Catalyst Profiles

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Binkai Chi, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang K, Yin C, Du X, Chen S, Wang J, Zhang L, Wang L, Yu Y, Chi B, Shi M, Wang C, Reed R, Zhou Y, Huang J, Cheng H. A U2-snRNP-independent role of SF3b in promoting mRNA export. Proc Natl Acad Sci U S A. 2019 04 16; 116(16):7837-7846. PMID: 30923118.
    Citations:    
  2. Chi B, O'Connell JD, Iocolano AD, Coady JA, Yu Y, Gangopadhyay J, Gygi SP, Reed R. The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex. Nucleic Acids Res. 2018 12 14; 46(22):11939-11951. PMID: 30398641.
    Citations:    Fields:    
  3. Fan J, Kuai B, Wang K, Wang L, Wang Y, Wu X, Chi B, Li G, Cheng H. mRNAs are sorted for export or degradation before passing through nuclear speckles. Nucleic Acids Res. 2018 09 19; 46(16):8404-8416. PMID: 30032211.
    Citations:    Fields:    
  4. Chi B, O'Connell JD, Yamazaki T, Gangopadhyay J, Gygi SP, Reed R. Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins. Sci Rep. 2018 06 08; 8(1):8755. PMID: 29884807.
    Citations:    Fields:    
  5. Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer-Hurt ME, Yin S, Eliasse Y, Adams E, Shaw CE, Reed R. U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish. Nucleic Acids Res. 2015 Mar 31; 43(6):3208-18. PMID: 25735748.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  6. Chi B, Wang K, Du Y, Gui B, Chang X, Wang L, Fan J, Chen S, Wu X, Li G, Cheng H. A Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18. Nucleic Acids Res. 2014 Jun; 42(11):7305-18. PMID: 24782531.
    Citations: 14     Fields:    Translation:HumansCells
  7. Chi B, Wang Q, Wu G, Tan M, Wang L, Shi M, Chang X, Cheng H. Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA. Nucleic Acids Res. 2013 Jan; 41(2):1294-306. PMID: 23222130.
    Citations: 36     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.