Harvard Catalyst Profiles

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Jonathan Sylvan Williams, M.D.

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Biography
1994 - 1998
Calabrese Scholaraship for Academic Excellence
1996
Alpha Omega Alpha Medical Honor Society
2003
Scholars in Endocrinology Award
2006 - 2009
Nomination, Excellence in Mentoring Award
2012
Early Career Mentoring Award

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 1R01HL144779-01 (WILLIAMS, GORDON H) Jan 20, 2019 - Dec 31, 2022
    NIH
    Salt Sensitive Hypertension and Striatin
    Role: Co-Investigator
  2. UL1TR002541 (NADLER, LEE MARSHALL) May 1, 2018 - Apr 30, 2023
    NIH/NCATS
    The Harvard Clinical and Translational Science Center
    Role: CT Academy Co-Director
  3. R01HL141406 (WAINFORD, RICHARD DAVID) May 1, 2018 - Feb 28, 2022
    NIH
    Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure
    Role: Site-PI
  4. R01HL136567 (ADLER, GAIL KURR) Feb 3, 2017 - Jan 31, 2021
    NIH/NHLBI
    Regulation of Aldosterone: The Effect of Statins
    Role: Co-Investigator
  5. R01HL127146 (WILLIAMS, JONATHAN S) Feb 1, 2016 - Jan 31, 2021
    NIH/NHLBI
    Epigenetic regulation of aldosterone and salt sensitivity in hypertension
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Haas AV, Baudrand R, Easly RM, Murray GR, Touyz RM, Pojoga LH, Jeunemaitre X, Hopkins PN, Rosner B, Williams JS, Williams GH, Adler GK. Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone. Hypertension. 2020 Aug 03; HYPERTENSIONAHA12014777. PMID: 32755411.
    Citations:    
  2. Hornik ES, Altman-Merino AE, Koefoed AW, Meyer KM, Stone IB, Green JA, Williams GH, Adler GK, Williams JS. A clinical trial to evaluate the effect of statin use on lowering aldosterone levels. BMC Endocr Disord. 2020 Jul 14; 20(1):105. PMID: 32664962.
    Citations:    
  3. Yuan RK, Zitting KM, Wang W, Buxton OM, Williams JS, Duffy JF, Czeisler CA. Fasting blood triglycerides vary with circadian phase in both young and older people. Physiol Rep. 2020 06; 8(11):e14453. PMID: 32519460.
    Citations:    
  4. Bayomy O, Zaheer S, Williams JS, Curhan G, Vaidya A. Disentangling the Relationships Between the Renin-Angiotensin-Aldosterone System, Calcium Physiology, and Risk for Kidney Stones. J Clin Endocrinol Metab. 2020 Jun 01; 105(6). PMID: 32163150.
    Citations:    
  5. Treesaranuwattana T, Wong KYH, Brooks DL, Tay CS, Williams GH, Williams JS, Pojoga LH. Lysine-Specific Demethylase-1 Deficiency Increases Agonist Signaling Via the Mineralocorticoid Receptor. Hypertension. 2020 Apr; 75(4):1045-1053. PMID: 32160100.
    Citations:    
  6. Carmichael CY, Kuwabara JT, Pascale CL, Moreira JD, Mahne SE, Kapusta DR, Rosene DL, Williams JS, Cunningham JT, Wainford RD. Hypothalamic Paraventricular Nucleus Gai2 (Guanine Nucleotide-Binding Protein Alpha Inhibiting Activity Polypeptide 2) Protein-Mediated Neural Control of the Kidney and the Salt Sensitivity of Blood Pressure. Hypertension. 2020 Apr; 75(4):1002-1011. PMID: 32148128.
    Citations:    
  7. Roumie CL, Hung AM, Russell GB, Basile J, Kreider KE, Nord J, Ramsey TM, Rastogi A, Sweeney ME, Tamariz L, Kostis WJ, Williams JS, Zias A, Cushman WC. Blood Pressure Control and the Association With Diabetes Mellitus Incidence: Results From SPRINT Randomized Trial. Hypertension. 2020 Feb; 75(2):331-338. PMID: 31865790.
    Citations:    
  8. Ranjit S, Wong JY, Tan JW, Sin Tay C, Lee JM, Yin Han Wong K, Pojoga LH, Brooks DL, Garza AE, Maris SA, Katayama IA, Williams JS, Rivera A, Adler GK, Williams GH, Romero JR. Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses. JCI Insight. 2019 11 01; 4(21). PMID: 31672933.
    Citations:    
  9. Chellappa SL, Vujovic N, Williams JS, Scheer FAJL. Impact of Circadian Disruption on Cardiovascular Function and Disease. Trends Endocrinol Metab. 2019 10; 30(10):767-779. PMID: 31427142.
    Citations:    
  10. Maris SA, Williams JS, Sun B, Brown S, Mitchell GF, Conlin PR. Interactions of the DASH Diet with the Renin-Angiotensin-Aldosterone System. Curr Dev Nutr. 2019 Sep; 3(9):nzz091. PMID: 31528838.
    Citations:    
  11. Haas AV, Hopkins PN, Brown NJ, Pojoga LH, Williams JS, Adler GK, Williams GH. Higher urinary cortisol levels associate with increased cardiovascular risk. Endocr Connect. 2019 Jun 01; 8(6):634-640. PMID: 31018177.
    Citations:    
  12. Huang Y, Ting PY, Yao TM, Homma T, Brooks D, Katayama Rangel I, Adler GK, Romero JR, Williams JS, Pojoga LH, Williams GH. Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production. J Endocrinol. 2019 02 01; 240(2):111-122. PMID: 30400034.
    Citations:    Fields:    
  13. Zitting KM, Vujovic N, Yuan RK, Isherwood CM, Medina JE, Wang W, Buxton OM, Williams JS, Czeisler CA, Duffy JF. Human Resting Energy Expenditure Varies with Circadian Phase. Curr Biol. 2018 11 19; 28(22):3685-3690.e3. PMID: 30416064.
    Citations:    Fields:    
  14. Zhang X, Frame AA, Williams JS, Wainford RD. GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study. Physiol Genomics. 2018 09 01; 50(9):724-725. PMID: 29906209.
    Citations:    Fields:    
  15. Shukri MZ, Tan JW, Manosroi W, Pojoga LH, Rivera A, Williams JS, Seely EW, Adler GK, Jaffe IZ, Karas RH, Williams GH, Romero JR. Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II. Hypertension. 2018 06; 71(6):1083-1090. PMID: 29686001.
    Citations: 1     Fields:    
  16. Williams JS, Autori PJ, Kidd SK, Piazza G, Connors MC, Czeisler CA, Scheuermaier KD, Duffy J, Klerman EB, Scheer FA, Kozak M, Driscoll SM, Goldhaber SZ. Heparin-Induced Thrombocytopenia in Healthy Individuals with Continuous Heparin Infusion. TH Open. 2018 Jan; 2(1):e49-e53. PMID: 31249929.
    Citations:    
  17. Zaheer S, Taquechel K, Brown JM, Adler GK, Williams JS, Vaidya A. A randomized intervention study to evaluate the effect of calcitriol therapy on the renin-angiotensin system in diabetes. J Renin Angiotensin Aldosterone Syst. 2018 Jan-Mar; 19(1):1470320317754178. PMID: 29562806.
    Citations:    Fields:    Translation:Humans
  18. Gupta T, Connors M, Tan JW, Manosroi W, Ahmed N, Ting PY, Garza AE, Romero JR, Hopkins PN, Williams JS, Williams GH. Striatin Gene Polymorphic Variants Are Associated With Salt Sensitive Blood Pressure in Normotensives and Hypertensives. Am J Hypertens. 2017 Dec 08; 31(1):124-131. PMID: 28985281.
    Citations:    Fields:    Translation:HumansAnimals
  19. Tan JW, Gupta T, Manosroi W, Yao TM, Hopkins PN, Williams JS, Adler GK, Romero JR, Williams GH. Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants. JCI Insight. 2017 12 07; 2(23). PMID: 29212952.
    Citations:    Fields:    
  20. Manosroi W, Tan JW, Rariy CM, Sun B, Goodarzi MO, Saxena AR, Williams JS, Pojoga LH, Lasky-Su J, Cui J, Guo X, Taylor KD, Chen YI, Xiang AH, Hsueh WA, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Seely EW. The Association of Estrogen Receptor-ß Gene Variation With Salt-Sensitive Blood Pressure. J Clin Endocrinol Metab. 2017 11 01; 102(11):4124-4135. PMID: 28938457.
    Citations: 1     Fields:    Translation:Humans
  21. Bress AP, King JB, Kreider KE, Beddhu S, Simmons DL, Cheung AK, Zhang Y, Doumas M, Nord J, Sweeney ME, Taylor AA, Herring C, Kostis WJ, Powell J, Rastogi A, Roumie CL, Wiggers A, Williams JS, Yunis R, Zias A, Evans GW, Greene T, Rocco MV, Cushman WC, Reboussin DM, Feinglos MN, Papademetriou V. Effect of Intensive Versus Standard Blood Pressure Treatment According to Baseline Prediabetes Status: A Post Hoc Analysis of a Randomized Trial. Diabetes Care. 2017 Aug 09. PMID: 28793997.
    Citations: 1     Fields:    
  22. Zaheer S, Brown JM, Connors M, Williams JS, Adler GK, Vaidya A. Angiotensin-Converting Enzyme Inhibition and Parathyroid Hormone Secretion. Int J Endocrinol. 2017; 2017:4138783. PMID: 28808443.
    Citations:    
  23. Leonardi GC, Oxnard GR, Haas A, Lang JP, Williams JS, Awad MM. Diabetic Ketoacidosis as an Immune-related Adverse Event from Pembrolizumab in Non-Small Cell Lung Cancer. J Immunother. 2017 Jul/Aug; 40(6):249-251. PMID: 28557813.
    Citations: 1     Fields:    Translation:Humans
  24. Baudrand R, Gupta N, Garza AE, Vaidya A, Leopold JA, Hopkins PN, Jeunemaitre X, Ferri C, Romero JR, Williams J, Loscalzo J, Adler GK, Williams GH, Pojoga LH. Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 09 28; 5(10). PMID: 27680666.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  25. Xiao Y, Thoresen DT, Miao L, Williams JS, Wang C, Atit RP, Wong SY, Brownell I. A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet. 2016 07; 12(7):e1006150. PMID: 27414798.
    Citations: 3     Fields:    Translation:AnimalsCells
  26. Baudrand R, Pojoga L, Vaidya A, Garza A, Vöhringer P, Jeunemaitre X, Hopkins P, Yao T, Williams J, Adler G, Williams G. Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects". Circulation. 2016 Apr 19; 133(16):e606. PMID: 27142613.
    Citations:    Fields:    Translation:Humans
  27. Baudrand R, Pojoga LH, Vaidya A, Garza AE, Vöhringer PA, Jeunemaitre X, Hopkins PN, Yao TM, Williams J, Adler GK, Williams GH. Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects. Circulation. 2015 Nov 10; 132(19):1825-33. PMID: 26432671.
    Citations: 5     Fields:    Translation:HumansAnimals
  28. Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Pojoga LH. A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics. Metabolism. 2015 Dec; 64(12):1674-81. PMID: 26475177.
    Citations: 6     Fields:    Translation:Humans
  29. Vaidya A, Brown JM, Williams JS. The renin-angiotensin-aldosterone system and calcium-regulatory hormones. J Hum Hypertens. 2015 Sep; 29(9):515-21. PMID: 25631218.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  30. Arora P, Reingold J, Baggish A, Guanaga DP, Wu C, Ghorbani A, Song Y, Chen-Tournaux A, Khan AM, Tainsh LT, Buys ES, Williams JS, Heublein DM, Burnett JC, Semigran MJ, Bloch KD, Scherrer-Crosbie M, Newton-Cheh C, Kaplan LM, Wang TJ. Weight loss, saline loading, and the natriuretic peptide system. J Am Heart Assoc. 2015 Jan 16; 4(1):e001265. PMID: 25595796.
    Citations: 6     Fields:    Translation:Humans
  31. Garza AE, Rariy CM, Sun B, Williams J, Lasky-Su J, Baudrand R, Yao T, Moize B, Hafiz WM, Romero JR, Adler GK, Ferri C, Hopkins PN, Pojoga LH, Williams GH. Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans. Hypertension. 2015 Jan; 65(1):211-217. PMID: 25368024.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  32. Hamnvik OP, Choueiri TK, Turchin A, McKay RR, Goyal L, Davis M, Kaymakcalan MD, Williams JS. Clinical risk factors for the development of hypertension in patients treated with inhibitors of the VEGF signaling pathway. Cancer. 2015 Jan 15; 121(2):311-9. PMID: 25236375.
    Citations: 32     Fields:    Translation:HumansCells
  33. Garg R, Sun B, Williams J. Effect of low salt diet on insulin resistance in salt-sensitive versus salt-resistant hypertension. Hypertension. 2014 Dec; 64(6):1384-7. PMID: 25185125.
    Citations: 2     Fields:    Translation:Humans
  34. Coutinho P, Vega C, Pojoga LH, Rivera A, Prado GN, Yao TM, Adler G, Torres-Grajales M, Maldonado ER, Ramos-Rivera A, Williams JS, Williams G, Romero JR. Aldosterone's rapid, nongenomic effects are mediated by striatin: a modulator of aldosterone's effect on estrogen action. Endocrinology. 2014 Jun; 155(6):2233-43. PMID: 24654783.
    Citations: 9     Fields:    Translation:AnimalsCells
  35. Seth B, Williams JS. Recent AHA/ACC cholesterol guidelines: vice or virtue? Metabolism. 2014 May; 63(5):605-6. PMID: 24560624.
    Citations: 1     Fields:    Translation:Humans
  36. Brown JM, Williams JS, Luther JM, Garg R, Garza AE, Pojoga LH, Ruan DT, Williams GH, Adler GK, Vaidya A. Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. Hypertension. 2014 Feb; 63(2):273-80. PMID: 24191286.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  37. Brown JM, Secinaro K, Williams JS, Vaidya A. Evaluating hormonal mechanisms of vitamin D receptor agonist therapy in diabetic kidney disease: the VALIDATE-D study. BMC Endocr Disord. 2013 Aug 23; 13:33. PMID: 23971740.
    Citations: 8     Fields:    
  38. Williams JS. Evolving research in nongenomic actions of aldosterone. Curr Opin Endocrinol Diabetes Obes. 2013 Jun; 20(3):198-203. PMID: 23519092.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  39. Vaidya A, Underwood PC, Annes JP, Sun B, Williams GH, Forman JP, Williams JS. The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes. Metabolism. 2013 Apr; 62(4):539-47. PMID: 23142162.
    Citations: 3     Fields:    Translation:Humans
  40. Krug AW, Tille E, Sun B, Pojoga L, Williams J, Chamarthi B, Lichtman AH, Hopkins PN, Adler GK, Williams GH. Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake. Age (Dordr). 2013 Oct; 35(5):1809-20. PMID: 23054827.
    Citations: 2     Fields:    Translation:HumansAnimals
  41. Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, Park MJ, Sobota RS, Underwood PC, Williams J, Sun B, Raby B, Lasky-Su J, Hopkins PN, Adler GK, Williams SM, Jose PA, Felder RA. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension. 2012 Nov; 60(5):1359-66. PMID: 22987918.
    Citations: 29     Fields:    Translation:Humans
  42. Underwood PC, Chamarthi B, Williams JS, Vaidya A, Garg R, Adler GK, Grotzke MP, Staskus G, Wadwekar D, Hopkins PN, Ferri C, McCall A, McClain D, Williams GH. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2012 Oct; 97(10):3775-82. PMID: 22865897.
    Citations: 7     Fields:    Translation:Humans
  43. Sun B, Chamarthi B, Williams JS, Krug AW, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH. Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension. J Clin Endocrinol Metab. 2012 Sep; 97(9):E1825-9. PMID: 22723323.
    Citations: 1     Fields:    Translation:Humans
  44. Rao AD, Sun B, Saxena A, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams JS. Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake. J Hum Hypertens. 2013 Mar; 27(3):176-80. PMID: 22648267.
    Citations: 13     Fields:    Translation:Humans
  45. Williams JS. The early-stage patient-oriented researcher in 2012: challenges and strategies. Clin Transl Sci. 2012 Jun; 5(3):221-2. PMID: 22686197.
    Citations:    Fields:    Translation:Humans
  46. Williams JS, Chamarthi B, Goodarzi MO, Pojoga LH, Sun B, Garza AE, Raby BA, Adler GK, Hopkins PN, Brown NJ, Jeunemaitre X, Ferri C, Fang R, Leonor T, Cui J, Guo X, Taylor KD, Ida Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Shi Y. Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Am J Hypertens. 2012 Jul; 25(7):812-7. PMID: 22534796.
    Citations: 9     Fields:    Translation:HumansAnimals
  47. Vaidya A, Sun B, Larson C, Forman JP, Williams JS. Vitamin D3 therapy corrects the tissue sensitivity to angiotensin ii akin to the action of a converting enzyme inhibitor in obese hypertensives: an interventional study. J Clin Endocrinol Metab. 2012 Jul; 97(7):2456-65. PMID: 22539586.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  48. Vaidya A, Williams JS. Vitamin D and insulin sensitivity: can gene association and pharmacogenetic studies of the vitamin D receptor provide clarity? Metabolism. 2012 Jun; 61(6):759-61. PMID: 22304841.
    Citations: 5     Fields:    Translation:Humans
  49. Larson C, Vaidya A, Sun B, Williams JS. Influence of dietary sodium modulation on electrocardiographic voltage criteria for left ventricular hypertrophy in normotensive individuals. J Investig Med. 2012 Jan; 60(1):39-43. PMID: 22089249.
    Citations:    Fields:    Translation:Humans
  50. Pojoga LH, Coutinho P, Rivera A, Yao TM, Maldonado ER, Youte R, Adler GK, Williams J, Turchin A, Williams GH, Romero JR. Activation of the mineralocorticoid receptor increases striatin levels. Am J Hypertens. 2012 Feb; 25(2):243-9. PMID: 22089104.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  51. Vaidya A, Williams JS. The relationship between vitamin D and the renin-angiotensin system in the pathophysiology of hypertension, kidney disease, and diabetes. Metabolism. 2012 Apr; 61(4):450-8. PMID: 22075270.
    Citations: 32     Fields:    Translation:HumansAnimals
  52. Underwood PC, Chamarthi B, Williams JS, Sun B, Vaidya A, Raby BA, Lasky-Su J, Hopkins PN, Adler GK, Williams GH. Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance. Metabolism. 2012 May; 61(5):667-71. PMID: 22075267.
    Citations: 5     Fields:    Translation:HumansCells
  53. Williams JS, Hopkins PN, Jeunemaitre X, Brown NJ. CYP4A11 T8590C polymorphism, salt-sensitive hypertension, and renal blood flow. J Hypertens. 2011 Oct; 29(10):1913-8. PMID: 21873888.
    Citations: 12     Fields:    Translation:Humans
  54. Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA. Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H1862-71. PMID: 21873498.
    Citations: 16     Fields:    Translation:AnimalsCells
  55. Vaidya A, Williams JS, Forman JP. The independent association between 25-hydroxyvitamin D and adiponectin and its relation with BMI in two large cohorts: the NHS and the HPFS. Obesity (Silver Spring). 2012 Jan; 20(1):186-91. PMID: 21760630.
    Citations: 24     Fields:    Translation:Humans
  56. Vaidya A, Sun B, Forman JP, Hopkins PN, Brown NJ, Kolatkar NS, Williams GH, Williams JS. The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians. Clin Endocrinol (Oxf). 2011 Jun; 74(6):783-90. PMID: 21521263.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  57. Pojoga LH, Underwood PC, Goodarzi MO, Williams JS, Adler GK, Jeunemaitre X, Hopkins PN, Raby BA, Lasky-Su J, Sun B, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH. Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension. J Clin Endocrinol Metab. 2011 Aug; 96(8):E1288-92. PMID: 21613355.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  58. Sun B, Williams JS, Pojoga L, Chamarthi B, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Brown NJ, Ferri C, Williams GH. Renin gene polymorphism: its relationship to hypertension, renin levels and vascular responses. J Renin Angiotensin Aldosterone Syst. 2011 Dec; 12(4):564-71. PMID: 21490026.
    Citations: 8     Fields:    Translation:Humans
  59. Vaidya A, Forman JP, Underwood PC, Hopkins PN, Williams GH, Pojoga LH, Williams JS. The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men. Eur J Endocrinol. 2011 Jun; 164(6):995-1002. PMID: 21402748.
    Citations: 17     Fields:    Translation:Humans
  60. Vaidya A, Pojoga L, Underwood PC, Forman JP, Hopkins PN, Williams GH, Williams JS. The association of plasma resistin with dietary sodium manipulation, the renin-angiotensin-aldosterone system, and 25-hydroxyvitamin D3 in human hypertension. Clin Endocrinol (Oxf). 2011 Mar; 74(3):294-9. PMID: 21050256.
    Citations: 10     Fields:    Translation:Humans
  61. Vaidya A, Forman JP, Hopkins PN, Seely EW, Williams JS. 25-Hydroxyvitamin D is associated with plasma renin activity and the pressor response to dietary sodium intake in Caucasians. J Renin Angiotensin Aldosterone Syst. 2011 Sep; 12(3):311-9. PMID: 21330422.
    Citations: 29     Fields:    Translation:HumansCTClinical Trials
  62. Underwood PC, Sun B, Williams JS, Pojoga LH, Raby B, Lasky-Su J, Hunt S, Hopkins PN, Jeunemaitre X, Adler GK, Williams GH. The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach. Metabolism. 2011 Aug; 60(8):1150-7. PMID: 21306748.
    Citations: 5     Fields:    Translation:Humans
  63. Vaidya A, Forman JP, Williams JS. Vitamin D and the vascular sensitivity to angiotensin II in obese Caucasians with hypertension. J Hum Hypertens. 2011 Nov; 25(11):672-8. PMID: 21124341.
    Citations: 19     Fields:    Translation:Humans
  64. Underwood PC, Sun B, Williams JS, Pojoga LH, Chamarthi B, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams GH. The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study. J Clin Endocrinol Metab. 2010 Sep; 95(9):E75-9. PMID: 20631015.
    Citations: 4     Fields:    Translation:Humans
  65. Sun B, Williams JS, Svetkey LP, Kolatkar NS, Conlin PR. Beta2-adrenergic receptor genotype affects the renin-angiotensin-aldosterone system response to the Dietary Approaches to Stop Hypertension (DASH) dietary pattern. Am J Clin Nutr. 2010 Aug; 92(2):444-9. PMID: 20519561.
    Citations: 7     Fields:    Translation:Humans
  66. Chamarthi B, Williams JS, Williams GH. A mechanism for salt-sensitive hypertension: abnormal dietary sodium-mediated vascular response to angiotensin-II. J Hypertens. 2010 May; 28(5):1020-6. PMID: 20216091.
    Citations: 22     Fields:    Translation:Humans
  67. Williams JS. Hypertension: spironolactone and resistant hypertension. Nat Rev Endocrinol. 2010 May; 6(5):248-50. PMID: 20414316.
    Citations: 1     Fields:    Translation:Humans
  68. Forman JP, Williams JS, Fisher ND. Plasma 25-hydroxyvitamin D and regulation of the renin-angiotensin system in humans. Hypertension. 2010 May; 55(5):1283-8. PMID: 20351344.
    Citations: 74     Fields:    Translation:Humans
  69. Vaidya A, Bentley-Lewis R, Jeunemaitre X, Adler GK, Williams JS. Dietary sodium alters the prevalence of electrocardiogram determined left ventricular hypertrophy in hypertension. Am J Hypertens. 2009 Jun; 22(6):669-73. PMID: 19265788.
    Citations: 3     Fields:    Translation:Humans
  70. Williams JS, Brown SM, Conlin PR. Videos in clinical medicine. Blood-pressure measurement. N Engl J Med. 2009 Jan 29; 360(5):e6. PMID: 19179309.
    Citations: 10     Fields:    Translation:Humans
  71. Chamarthi B, Kolatkar NS, Hunt SC, Williams JS, Seely EW, Brown NJ, Murphey LJ, Jeunemaitre X, Williams GH. Urinary free cortisol: an intermediate phenotype and a potential genetic marker for a salt-resistant subset of essential hypertension. J Clin Endocrinol Metab. 2007 Apr; 92(4):1340-6. PMID: 17264181.
    Citations: 8     Fields:    Translation:Humans
  72. Gumieniak O, Perlstein TS, Williams JS, Hopkins PN, Brown NJ, Raby BA, Williams GH. Ala92 type 2 deiodinase allele increases risk for the development of hypertension. Hypertension. 2007 Mar; 49(3):461-6. PMID: 17224473.
    Citations: 21     Fields:    Translation:Humans
  73. Williams JS, Williams GH, Ricchuiti V. Low-renin hypertension is associated with elevated NT-proBNP concentrations on a high sodium diet. Proceedings of the 22nd Annual Scientific Meeting of the American Society of Hypertension. 2007.
  74. Raji A, Williams JS, Hopkins PN, Simonson DC, Williams GH. Familial aggregation of insulin resistance and cardiovascular risk factors in hypertension. J Clin Hypertens (Greenwich). 2006 Nov; 8(11):791-6. PMID: 17086019.
    Citations: 3     Fields:    Translation:Humans
  75. Pojoga L, Kolatkar NS, Williams JS, Perlstein TS, Jeunemaitre X, Brown NJ, Hopkins PN, Raby BA, Williams GH. Beta-2 adrenergic receptor diplotype defines a subset of salt-sensitive hypertension. Hypertension. 2006 Nov; 48(5):892-900. PMID: 17015767.
    Citations: 21     Fields:    Translation:HumansAnimals
  76. Williams JS, Solomon SD, Crivaro M, Conlin PR. Dietary sodium intake modulates myocardial relaxation responsiveness to angiotensin II. Transl Res. 2006 Aug; 148(2):49-54. PMID: 16890144.
    Citations: 2     Fields:    Translation:Humans
  77. Szmuilowicz ED, Adler GK, Williams JS, Green DE, Yao TM, Hopkins PN, Seely EW. Relationship between aldosterone and progesterone in the human menstrual cycle. J Clin Endocrinol Metab. 2006 Oct; 91(10):3981-7. PMID: 16868049.
    Citations: 11     Fields:    Translation:Humans
  78. Raji A, Gerhard-Herman MD, Williams JS, O'connor ME, Simonson DC. Effect of pioglitazone on insulin sensitivity, vascular function and cardiovascular inflammatory markers in insulin-resistant non-diabetic Asian Indians. Diabet Med. 2006 May; 23(5):537-43. PMID: 16681563.
    Citations: 3     Fields:    Translation:Humans
  79. Williams JS, Williams GH, Raji A, Jeunemaitre X, Brown NJ, Hopkins PN, Conlin PR. Prevalence of primary hyperaldosteronism in mild to moderate hypertension without hypokalaemia. J Hum Hypertens. 2006 Feb; 20(2):129-36. PMID: 16292348.
    Citations: 20     Fields:    Translation:HumansPHPublic Health
  80. *Raji A, *Williams JS, Hopkins PN, Simonson DC, Williams GH. Familial aggregation of insulin resistance in hypertension. Proceedings of the American Diabetes Association. 2006.
  81. Williams JS, Raji A, Conlin PR, Hopkins PN, Jeunemaitre X, Williams GH. Non-modulating hypertension is associated with insulin resistance and the Lys528Arg variant of human adipocyte derived leucine aminopeptidase. Proceedings of the 60th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research. 2006.
  82. Williams JS, Williams GH, Jeunemaitre X, Hopkins PN, Conlin PR. Influence of dietary sodium on the renin-angiotensin-aldosterone system and prevalence of left ventricular hypertrophy by EKG criteria. J Hum Hypertens. 2005 Feb; 19(2):133-8. PMID: 15361890.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  83. Williams JS, Williams GH, Raji A, Jeuenemaitre X, Brown NJ, Hopkins PN, Conlin PR. Low prevalence of primary hyperaldosteronism in general hypertension. Proceedings of the 20th Annual Scientific Meeting of the American Society of Hypertension. 2005.
  84. Williams JR. Depression as a mediator between spousal bereavement and mortality from cardiovascular disease: appreciating and managing the adverse health consequences of depression in an elderly surviving spouse. South Med J. 2005 Jan; 98(1):90-5. PMID: 15678641.
    Citations: 2     Fields:    Translation:Humans
  85. Williams JS, Williams GH, Jeunemaitre X, Hopkins PN, Brown NJ, Conlin PR. Loss of normal dietary sodium blood pressure response to angiotensin II infusion in essential hypertension. Proceedings of the American Society of Hypertension. 2004.
  86. Williams JS, Solomon SD, Crivaro M, Gerhard-Herman, M, Conlin PR. Dietary sodium intake modulates myocardial relaxation velocity in normal healthy individuals. Proceedings of Clinical Research 2004. 2004.
  87. Williams JS, Williams GH. 50th anniversary of aldosterone. J Clin Endocrinol Metab. 2003 Jun; 88(6):2364-72. PMID: 12788829.
    Citations: 30     Fields:    Translation:HumansAnimals
  88. Williams JS, Williams GH, Jeunemaitre X, Hopkins PN, Hurwitz S, Conlin PR. Prevalence of left ventricular hypertrophy by EKG criteria in low-renin hypertension. Proceedings of the 57th Annual Fall Conference and Scientific Sessions of the Council on High Blood Pressure Research. 2003.
  89. Conlin, PR, Bryan McIver, Williams JS. A diagnostic approach for evaluating the adrenal mass. Hospital Physician Board Review Manual, Endocrinology. 2002; 1-12.
  90. Williams JS, Baker J, Nelson LM, Ward K, Smotkin D. No Evidence for somatic deletion of the COL4A5 and COL4A6 collagen gene of the X chromosome in benign uterine leiomyomata. Proceedings of the Annual Program of the Society for Gynecologic Investigations. 1993.
  91. Williams JS, Baker J, Dildy G, Ward K. Rhesus D typing of the fetus at risk for isoimmunization using DNA from amniotic fluid. Proceedings of the Annual Program of the Society for Gynecologic Investigations. 1993.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.