Harvard Catalyst Profiles

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David Bargiela, M.D.


Imperial College London, UKMBBS2012Medicine
University of Cambridge, UKPhD2020Immunometabolism
2014 - 2015
Kennedy Scholarship - Harvard University

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bargiela D, Cunha PP, Veliça P, Foskolou IP, Barbieri L, Rundqvist H, Johnson RS. Vitamin B6 Metabolism Determines T Cell Anti-Tumor Responses. Front Immunol. 2022; 13:837669. PMID: 35251031; PMCID: PMC8891565.
    Citations:    Fields:    Translation:AnimalsCells
  2. Roda RH, Bargiela D, Chen W, Perry K, Ellis RJ, Clifford DB, Bharti A, Kallianpur AR, Oliveira MF, Diaz MM, Rubin LH, Gavegnano C, McArthur JC, Hoke A, Polydefkis M. Large Mitochondrial DNA Deletions in HIV Sensory Neuropathy. Neurology. 2021 07 13; 97(2):e156-e165. PMID: 33947785; PMCID: PMC8279564.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  3. Hiensch AE, Mijwel S, Bargiela D, Wengström Y, May AM, Rundqvist H. Inflammation Mediates Exercise Effects on Fatigue in Patients with Breast Cancer. Med Sci Sports Exerc. 2021 03 01; 53(3):496-504. PMID: 32910094; PMCID: PMC7886356.
    Citations: 3     Fields:    Translation:Humans
  4. Veliça P, Cunha PP, Vojnovic N, Foskolou IP, Bargiela D, Gojkovic M, Rundqvist H, Johnson RS. Modified Hypoxia-Inducible Factor Expression in CD8+ T Cells Increases Antitumor Efficacy. Cancer Immunol Res. 2021 04; 9(4):401-414. PMID: 33602720; PMCID: PMC7611205.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  5. Rundqvist H, Veliça P, Barbieri L, Gameiro PA, Bargiela D, Gojkovic M, Mijwel S, Reitzner SM, Wulliman D, Ahlstedt E, Ule J, Östman A, Johnson RS. Cytotoxic T-cells mediate exercise-induced reductions in tumor growth. Elife. 2020 10 23; 9. PMID: 33095157.
    Citations: 22     Fields:    Translation:AnimalsCells
  6. Foskolou IP, Barbieri L, Vernet A, Bargiela D, Cunha PP, Velica P, Suh E, Pietsch S, Matuleviciute R, Rundqvist H, McIntyre D, Smith KGC, Johnson RS. The S enantiomer of 2-hydroxyglutarate increases central memory CD8 populations and improves CAR-T therapy outcome. Blood Adv. 2020 09 22; 4(18):4483-4493. PMID: 32941648.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  7. Sim J, Cowburn AS, Palazon A, Madhu B, Tyrakis PA, Macías D, Bargiela DM, Pietsch S, Gralla M, Evans CE, Kittipassorn T, Chey YCJ, Branco CM, Rundqvist H, Peet DJ, Johnson RS. The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia. Cell Metab. 2018 04 03; 27(4):898-913.e7. PMID: 29617647; PMCID: PMC5887987.
    Citations: 20     Fields:    Translation:AnimalsCells
  8. Bargiela D, Burr SP, Chinnery PF. Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions. Trends Endocrinol Metab. 2018 04; 29(4):249-259. PMID: 29501229.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  9. Bargiela D, Verkerk MM, Wee I, Welman K, Ng E, Choong AMTL. The endovascular management of neurofibromatosis-associated aneurysms: A systematic review. Eur J Radiol. 2018 Mar; 100:66-75. PMID: 29496081.
    Citations: 6     Fields:    Translation:Humans
  10. Bargiela D, Chinnery PF. Mitochondria in neuroinflammation - Multiple sclerosis (MS), leber hereditary optic neuropathy (LHON) and LHON-MS. Neurosci Lett. 2019 09 25; 710:132932. PMID: 28668384.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  11. Bargiela D, Bianchi MT, Westover MB, Chibnik LB, Healy BC, De Jager PL, Xia Z. Selection of first-line therapy in multiple sclerosis using risk-benefit decision analysis. Neurology. 2017 Feb 14; 88(7):677-684. PMID: 28087821; PMCID: PMC5317380.
    Citations: 6     Fields:    Translation:Humans
  12. Nightingale H, Pfeffer G, Bargiela D, Horvath R, Chinnery PF. Emerging therapies for mitochondrial disorders. Brain. 2016 06; 139(Pt 6):1633-48. PMID: 27190030; PMCID: PMC4892756.
    Citations: 25     Fields:    Translation:HumansAnimals
  13. Bargiela D, Shanmugarajah P, Lo C, Blakely EL, Taylor RW, Horvath R, Wharton S, Chinnery PF, Hadjivassiliou M. Mitochondrial pathology in progressive cerebellar ataxia. Cerebellum Ataxias. 2015; 2:16. PMID: 26640698; PMCID: PMC4670505.
    Citations: 16     
  14. Bargiela D, Yu-Wai-Man P, Keogh M, Horvath R, Chinnery PF. Prevalence of neurogenetic disorders in the North of England. Neurology. 2015 Oct 06; 85(14):1195-201. PMID: 26341866; PMCID: PMC4607600.
    Citations: 9     Fields:    Translation:Humans
  15. Bove R, Malik MT, Diaz-Cruz C, Chua A, Saraceno TJ, Bargiela D, Greeke E, Glanz BI, Healy BC, Chitnis T. The 2D:4D ratio, a proxy for prenatal androgen levels, differs in men with and without MS. Neurology. 2015 Oct 06; 85(14):1209-13. PMID: 26341868; PMCID: PMC4607599.
    Citations: 6     Fields:    Translation:Humans
  16. Sewpaul A, Bargiela D, James A, Johnson SJ, French JJ. Spontaneous Regression of a Carcinoid Tumor following Pregnancy. Case Rep Endocrinol. 2014; 2014:481823. PMID: 25587468; PMCID: PMC4283420.
    Citations: 3     
  17. Pyle A, Smertenko T, Bargiela D, Griffin H, Duff J, Appleton M, Douroudis K, Pfeffer G, Santibanez-Koref M, Eglon G, Yu-Wai-Man P, Ramesh V, Horvath R, Chinnery PF. Exome sequencing in undiagnosed inherited and sporadic ataxias. Brain. 2015 Feb; 138(Pt 2):276-83. PMID: 25497598; PMCID: PMC4306819.
    Citations: 54     Fields:    Translation:Humans
  18. Erritzoe D, Tziortzi A, Bargiela D, Colasanti A, Searle GE, Gunn RN, Beaver JD, Waldman A, Nutt DJ, Bani M, Merlo-Pich E, Rabiner EA, Lingford-Hughes A. In vivo imaging of cerebral dopamine D3 receptors in alcoholism. Neuropsychopharmacology. 2014 Jun; 39(7):1703-12. PMID: 24469594; PMCID: PMC4023144.
    Citations: 27     Fields:    Translation:HumansCells
  19. Bargiela D, Eglon G, Horvath R, Chinnery PF. An under-recognised cause of spastic paraparesis in middle-aged women. Pract Neurol. 2014 Jun; 14(3):182-4. PMID: 24154795; PMCID: PMC4040405.
    Citations: 2     Fields:    Translation:Humans
  20. Verkerk MM, Bargiela D. How to appraise medical apps: a guideline-based framework. BMJ Careers. 2013.
  21. Bargiela D, Verkerk MM. The clinician-programmer: designing the future of medical practice. BMJ Careers. 2013.
  22. Russell S, Moon T, Bargiela D, Sokolov E, Bain PG. The 'attack of the demyelinator'. Pract Neurol. 2013 Aug; 13(4):276-7. PMID: 23703943.
    Citations: 1     Fields:    Translation:Humans
  23. Bargiela D, Lyall H, Mewasingh L. Oral acyclovir suppression after neonatal herpes. N Engl J Med. 2012 01 05; 366(1):90; author reply 90-1. PMID: 22216852.
    Citations: 1     Fields:    Translation:Humans
  24. Welman K, Bargiela D, Choong AM, Das S. Horner's syndrome: an incidental confounder. Br J Hosp Med (Lond). 2012 Jan; 73(1):50-1. PMID: 22241412.
    Citations:    Fields:    Translation:Humans
  25. Bargiela D, Mullin S, Manji, H. . The Evolving Epidemic of HIV-associated Sensory Neuropathy in sub- Saharan Africa. CML Neurology. 2012; 3(28):69-73.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.