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Soon Gang Choi, Ph.D.

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Biography
Illinois Institute of Technology, ChicagoBS05/2004Biology
University of Michigan , Ann ArborMS05/2006MCDB
Mount Sinai School of Medicine, New YorkPhD05/2012Pharmacology and Systems Biology

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. (Soon Gang Choi) Jul 1, 2017 - Dec 31, 2019
    Claudia Adams Barr Program
    Druggability of the cancer interactome: High-throughput discovery of chemical modulators of protein-protein interactions
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, Simonovsky E, Tasan M, Tejeda A, Tropepe V, Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J, Hill DE, Vidal M, Roth FP, Calderwood MA. A reference map of the human binary protein interactome. Nature. 2020 04; 580(7803):402-408. PMID: 32296183.
    Citations:    
  2. Choi SG, Olivet J, Cassonnet P, Vidalain PO, Luck K, Lambourne L, Spirohn K, Lemmens I, Dos Santos M, Demeret C, Jones L, Rangarajan S, Bian W, Coutant EP, Janin YL, van der Werf S, Trepte P, Wanker EE, De Las Rivas J, Tavernier J, Twizere JC, Hao T, Hill DE, Vidal M, Calderwood MA, Jacob Y. Maximizing binary interactome mapping with a minimal number of assays. Nat Commun. 2019 08 29; 10(1):3907. PMID: 31467278.
    Citations:    
  3. Choi SG, Richardson A, Lambourne L, Hill DE, Vidal M. Protein Interactomics by Two-Hybrid Methods. Methods Mol Biol. 2018; 1794:1-14. PMID: 29855947.
    Citations:    Fields:    
  4. Cafarelli TM, Desbuleux A, Wang Y, Choi SG, De Ridder D, Vidal M. Mapping, modeling, and characterization of protein-protein interactions on a proteomic scale. Curr Opin Struct Biol. 2017 06; 44:201-210. PMID: 28575754.
    Citations:    Fields:    Translation:Humans
  5. Stern E, Ruf-Zamojski F, Zalepa-King L, Pincas H, Choi SG, Peskin CS, Hayot F, Turgeon JL, Sealfon SC. Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency. J Biol Chem. 2017 06 09; 292(23):9815-9829. PMID: 28385888.
    Citations: 3     Fields:    Translation:Humans
  6. Choi SG, Wang Q, Jia J, Chikina M, Pincas H, Dolios G, Sasaki K, Wang R, Minamino N, Salton SR, Sealfon SC. Characterization of Gonadotrope Secretoproteome Identifies Neurosecretory Protein VGF-derived Peptide Suppression of Follicle-stimulating Hormone Gene Expression. J Biol Chem. 2016 Sep 30; 291(40):21322-21334. PMID: 27466366.
    Citations: 2     Fields:    Translation:AnimalsCells
  7. Choi SG, Wang Q, Jia J, Pincas H, Turgeon JL, Sealfon SC. Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone ß-subunit (FSHß) gene expression. J Biol Chem. 2014 Jun 06; 289(23):16164-75. PMID: 24778184.
    Citations: 6     Fields:    Translation:AnimalsCells
  8. Pincas H, Choi SG, Wang Q, Jia J, Turgeon JL, Sealfon SC. Outside the box signaling: secreted factors modulate GnRH receptor-mediated gonadotropin regulation. Mol Cell Endocrinol. 2014 Mar 25; 385(1-2):56-61. PMID: 23994024.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  9. Choi SG, Jia J, Pfeffer RL, Sealfon SC. G proteins and autocrine signaling differentially regulate gonadotropin subunit expression in pituitary gonadotrope. J Biol Chem. 2012 Jun 15; 287(25):21550-60. PMID: 22549790.
    Citations: 12     Fields:    Translation:AnimalsCells
  10. Yuen T, Choi SG, Pincas H, Waring DW, Sealfon SC, Turgeon JL. Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes. Mol Cell Endocrinol. 2012 Mar 05; 350(1):10-9. PMID: 22127306.
    Citations: 2     Fields:    Translation:AnimalsCells
  11. Choi SG, Ruf-Zamojski F, Pincas H, Roysam B, Sealfon SC. Characterization of a MAPK scaffolding protein logic gate in gonadotropes. Mol Endocrinol. 2011 Jun; 25(6):1027-39. PMID: 21436256.
    Citations: 8     Fields:    Translation:AnimalsCells
  12. Shtilbans A, Choi SG, Fowkes ME, Khitrov G, Shahbazi M, Ting J, Zhang W, Sun Y, Sealfon SC, Lange DJ. Differential gene expression in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2011 Jul; 12(4):250-6. PMID: 21375368.
    Citations: 8     Fields:    Translation:HumansAnimals
  13. Fink MY, Pincas H, Choi SG, Nudelman G, Sealfon SC. Research resource: Gonadotropin-releasing hormone receptor-mediated signaling network in LbetaT2 cells: a pathway-based web-accessible knowledgebase. Mol Endocrinol. 2010 Sep; 24(9):1863-71. PMID: 20592162.
    Citations: 8     Fields:    Translation:AnimalsCells
  14. Shimoni Y, Fink MY, Choi SG, Sealfon SC. Plato's cave algorithm: inferring functional signaling networks from early gene expression shadows. PLoS Comput Biol. 2010 Jun 24; 6(6):e1000828. PMID: 20585619.
    Citations: 4     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.