Harvard Catalyst Profiles

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George Eng, M.D.,Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hwang WL, Jagadeesh KA, Guo JA, Hoffman HI, Yadollahpour P, Reeves JW, Mohan R, Drokhlyansky E, Van Wittenberghe N, Ashenberg O, Farhi SL, Schapiro D, Divakar P, Miller E, Zollinger DR, Eng G, Schenkel JM, Su J, Shiau C, Yu P, Freed-Pastor WA, Abbondanza D, Mehta A, Gould J, Lambden C, Porter CBM, Tsankov A, Dionne D, Waldman J, Cuoco MS, Nguyen L, Delorey T, Phillips D, Barth JL, Kem M, Rodrigues C, Ciprani D, Roldan J, Zelga P, Jorgji V, Chen JH, Ely Z, Zhao D, Fuhrman K, Fropf R, Beechem JM, Loeffler JS, Ryan DP, Weekes CD, Ferrone CR, Qadan M, Aryee MJ, Jain RK, Neuberg DS, Wo JY, Hong TS, Xavier R, Aguirre AJ, Rozenblatt-Rosen O, Mino-Kenudson M, Castillo CF, Liss AS, Ting DT, Jacks T, Regev A. Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment. Nat Genet. 2022 08; 54(8):1178-1191. PMID: 35902743.
    Citations:    Fields:    
  2. Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz ÖH, Kwon DS. Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival. Clin Infect Dis. 2022 03 23; 74(6):1081-1084. PMID: 34245255; PMCID: PMC8406863.
    Citations: 5     Fields:    Translation:HumansCells
  3. Hwabejire JO, Kaafarani HMA, Mashbari H, Misdraji J, Fagenholz PJ, Gartland RM, Abraczinskas DR, Mehta RS, Paranjape CN, Eng G, Saillant NN, Parks J, Fawley JA, Lee J, King DR, Mendoza AE, Velmahos GC. Bowel Ischemia in COVID-19 Infection: One-Year Surgical Experience. Am Surg. 2021 Dec; 87(12):1893-1900. PMID: 34772281.
    Citations: 5     Fields:    Translation:HumansCells
  4. Cole AJ, Slutzman JE, Ryan ET, Lev MH, Eng G. Case 34-2021: A 38-Year-Old Man with Altered Mental Status and New Onset of Seizures. N Engl J Med. 2021 Nov 11; 385(20):1894-1902. PMID: 34758256.
    Citations:    Fields:    Translation:Humans
  5. Westcott PMK, Sacks NJ, Schenkel JM, Ely ZA, Smith O, Hauck H, Jaeger AM, Zhang D, Backlund CM, Beytagh MC, Patten JJ, Elbashir R, Eng G, Irvine DJ, Yilmaz OH, Jacks T. Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer. Nat Cancer. 2021 10; 2(10):1071-1085. PMID: 34738089; PMCID: PMC8562866.
    Citations: 4     Translation:HumansAnimalsCells
  6. Schenkel JM, Herbst RH, Canner D, Li A, Hillman M, Shanahan SL, Gibbons G, Smith OC, Kim JY, Westcott P, Hwang WL, Freed-Pastor WA, Eng G, Cuoco MS, Rogers P, Park JK, Burger ML, Rozenblatt-Rosen O, Cong L, Pauken KE, Regev A, Jacks T. Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes. Immunity. 2021 10 12; 54(10):2338-2353.e6. PMID: 34534439; PMCID: PMC8604155.
    Citations: 16     Fields:    Translation:AnimalsCells
  7. Freed-Pastor WA, Lambert LJ, Ely ZA, Pattada NB, Bhutkar A, Eng G, Mercer KL, Garcia AP, Lin L, Rideout WM, Hwang WL, Schenkel JM, Jaeger AM, Bronson RT, Westcott PMK, Hether TD, Divakar P, Reeves JW, Deshpande V, Delorey T, Phillips D, Yilmaz OH, Regev A, Jacks T. The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell. 2021 10 11; 39(10):1342-1360.e14. PMID: 34358448; PMCID: PMC8511341.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  8. Alba GA, Samokhin AO, Wang RS, Zhang YY, Wertheim BM, Arons E, Greenfield EA, Lundberg Slingsby MH, Ceglowski JR, Haley KJ, Bowman FP, Yu YR, Haney JC, Eng G, Mitchell RN, Sheets A, Vargas SO, Seo S, Channick RN, Leary PJ, Rajagopal S, Loscalzo J, Battinelli EM, Maron BA. NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. Am J Respir Crit Care Med. 2021 06 15; 203(12):1533-1545. PMID: 33523764; PMCID: PMC8483217.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  9. Zhang J, Huang YJ, Yoon JY, Kemmitt J, Wright C, Schneider K, Sphabmixay P, Hernandez-Gordillo V, Holcomb SJ, Bhushan B, Rohatgi G, Benton K, Carpenter D, Kester JC, Eng G, Breault DT, Yilmaz O, Taketani M, Voigt CA, Carrier RL, Trumper DL, Griffith LG. Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in continuous culture. Med (N Y). 2021 01 15; 2(1):74-98.e9. PMID: 33511375; PMCID: PMC7839961.
    Citations: 13     Translation:HumansAnimalsCells
  10. Trapecar M, Communal C, Velazquez J, Maass CA, Huang YJ, Schneider K, Wright CW, Butty V, Eng G, Yilmaz O, Trumper D, Griffith LG. Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids. Cell Syst. 2020 03 25; 10(3):223-239.e9. PMID: 32191873.
    Citations: 32     Fields:    Translation:HumansCells
  11. Turbett SE, Anahtar MN, Pattanayak V, Azar MM, Coffey KC, Eng G, Rudolf JW, Lewandrowski KB, Baron J, Rosenberg ES, Branda JA. Use of Routine Complete Blood Count Results to Rule Out Anaplasmosis Without the Need for Specific Diagnostic Testing. Clin Infect Dis. 2020 03 03; 70(6):1215-1221. PMID: 31044232.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  12. Lee M, Eng G, Barbari SR, Deshpande V, Shcherbakova PV, Gala MK. Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors. Clin Transl Gastroenterol. 2020 03; 11(3):e00149. PMID: 32352724; PMCID: PMC7145036.
    Citations: 2     Fields:    Translation:HumansCells
  13. Fasano A, Leonard MM, Mitchell DM, Eng G. Case 1-2020: An 11-Year-Old Boy with Vomiting and Weight Loss. N Engl J Med. 2020 Jan 09; 382(2):180-189. PMID: 31914246; PMCID: PMC8176458.
    Citations:    Fields:    Translation:Humans
  14. Cheng CW, Biton M, Haber AL, Gunduz N, Eng G, Gaynor LT, Tripathi S, Calibasi-Kocal G, Rickelt S, Butty VL, Moreno-Serrano M, Iqbal AM, Bauer-Rowe KE, Imada S, Ulutas MS, Mylonas C, Whary MT, Levine SS, Basbinar Y, Hynes RO, Mino-Kenudson M, Deshpande V, Boyer LA, Fox JG, Terranova C, Rai K, Piwnica-Worms H, Mihaylova MM, Regev A, Yilmaz ÖH. Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell. 2019 08 22; 178(5):1115-1131.e15. PMID: 31442404; PMCID: PMC6732196.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  15. Walley AY, Wakeman SE, Eng G. Case 6-2019: A 29-Year-Old Woman with Nausea, Vomiting, and Diarrhea. N Engl J Med. 2019 02 21; 380(8):772-779. PMID: 30786192.
    Citations:    Fields:    Translation:HumansPHPublic Health
  16. Eng G, Braverman J, Yilmaz ÖH. CRAD as a cytoskeletal tumour suppressor. Nat Cell Biol. 2018 11; 20(11):1232-1233. PMID: 30361696.
    Citations: 1     Fields:    Translation:HumansCells
  17. Turbett SE, Tsiaras WG, McDermott S, Eng G. Case 26-2018: A 48-Year-Old Man with Fever, Chills, Myalgias, and Rash. N Engl J Med. 2018 Aug 23; 379(8):775-785. PMID: 30134139.
    Citations:    Fields:    Translation:HumansCells
  18. Knuesel SJ, Guseh JS, Karp Leaf R, Ciaranello AL, Eng GM. Case 6-2018: A 35-Year-Old Woman with Headache, Subjective Fever, and Anemia. N Engl J Med. 2018 Feb 22; 378(8):753-760. PMID: 29466149.
    Citations: 1     Fields:    Translation:HumansCells
  19. Taylor MS, Altukhov I, Molloy KR, Mita P, Jiang H, Adney EM, Wudzinska A, Badri S, Ischenko D, Eng G, Burns KH, Fenyö D, Chait BT, Alexeev D, Rout MP, Boeke JD, LaCava J. Dissection of affinity captured LINE-1 macromolecular complexes. Elife. 2018 01 08; 7. PMID: 29309035.
    Citations: 29     Fields:    Translation:HumansCells
  20. Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol. 2017 12 08; 35(12):1211. PMID: 29220013.
    Citations:    Fields:    
  21. Raja AS, Miller ES, Flores EJ, Wakeman SE, Eng G. Case 37-2017. A 36-Year-Old Man with Unintentional Opioid Overdose. N Engl J Med. 2017 Nov 30; 377(22):2181-2188. PMID: 29171813.
    Citations: 1     Fields:    Translation:Humans
  22. Kradin RL, Eng G, Christiani DC. Diffuse peritoneal mesothelioma: A case series of 62 patients including paraoccupational exposures to chrysotile asbestos. Am J Ind Med. 2017 Nov; 60(11):963-967. PMID: 28940402.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  23. Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera FJ, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol. 2017 06; 35(6):569-576. PMID: 28459449; PMCID: PMC5462879.
    Citations: 111     Fields:    Translation:AnimalsCells
  24. Lee BW, Liu B, Pluchinsky A, Kim N, Eng G, Vunjak-Novakovic G. Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue. Adv Healthc Mater. 2016 Apr 20; 5(8):900-6. PMID: 26865105.
    Citations: 7     Fields:    Translation:AnimalsCells
  25. Eng G, Lee BW, Protas L, Gagliardi M, Brown K, Kass RS, Keller G, Robinson RB, Vunjak-Novakovic G. Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nat Commun. 2016 Jan 19; 7:10312. PMID: 26785135.
    Citations: 57     Fields:    Translation:HumansCells
  26. Halushka MK, Eng G, Collins AB, Judge DP, Semigran MJ, Stone JR. Optimization of Serum Immunoglobulin Free Light Chain Analysis for Subclassification of Cardiac Amyloidosis. J Cardiovasc Transl Res. 2015 Jun; 8(4):264-8. PMID: 25925232.
    Citations: 3     Fields:    Translation:Humans
  27. Yuan X, Eng GM, Arkonac DE, Chao PH, Vunjak-Novakovic G. Endothelial cells enhance the migration of bovine meniscus cells. Arthritis Rheumatol. 2015 Jan; 67(1):182-92. PMID: 25307081; PMCID: PMC4280351.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  28. Martins AM, Eng G, Caridade SG, Mano JF, Reis RL, Vunjak-Novakovic G. Electrically conductive chitosan/carbon scaffolds for cardiac tissue engineering. Biomacromolecules. 2014 Feb 10; 15(2):635-43. PMID: 24417502.
    Citations: 55     Fields:    Translation:AnimalsCells
  29. Godier-Furnémont AF, Tekabe Y, Kollaros M, Eng G, Morales A, Vunjak-Novakovic G, Johnson LL. Noninvasive imaging of myocyte apoptosis following application of a stem cell-engineered delivery platform to acutely infarcted myocardium. J Nucl Med. 2013 Jun; 54(6):977-83. PMID: 23616583.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  30. Eng G, Lee BW, Parsa H, Chin CD, Schneider J, Linkov G, Sia SK, Vunjak-Novakovic G. Assembly of complex cell microenvironments using geometrically docked hydrogel shapes. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4551-6. PMID: 23487790.
    Citations: 32     Fields:    Translation:HumansCellsCTClinical Trials
  31. Lovett M, Eng G, Kluge JA, Cannizzaro C, Vunjak-Novakovic G, Kaplan DL. Tubular silk scaffolds for small diameter vascular grafts. Organogenesis. 2010 Oct-Dec; 6(4):217-24. PMID: 21220960.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  32. Wan LQ, Kang SM, Eng G, Grayson WL, Lu XL, Huo B, Gimble J, Guo XE, Mow VC, Vunjak-Novakovic G. Geometric control of human stem cell morphology and differentiation. Integr Biol (Camb). 2010 Aug; 2(7-8):346-53. PMID: 20652175.
    Citations: 24     Fields:    Translation:HumansCells
  33. Trkov S, Eng G, Di Liddo R, Parnigotto PP, Vunjak-Novakovic G. Micropatterned three-dimensional hydrogel system to study human endothelial-mesenchymal stem cell interactions. J Tissue Eng Regen Med. 2010 Mar; 4(3):205-15. PMID: 19998330.
    Citations: 36     Fields:    Translation:HumansCells
  34. Ifkovits JL, Devlin JJ, Eng G, Martens TP, Vunjak-Novakovic G, Burdick JA. Biodegradable fibrous scaffolds with tunable properties formed from photo-cross-linkable poly(glycerol sebacate). ACS Appl Mater Interfaces. 2009 Sep; 1(9):1878-86. PMID: 20160937.
    Citations: 21     Fields:    Translation:AnimalsCellsPHPublic Health
  35. Martens TP, Godier AF, Parks JJ, Wan LQ, Koeckert MS, Eng GM, Hudson BI, Sherman W, Vunjak-Novakovic G. Percutaneous cell delivery into the heart using hydrogels polymerizing in situ. Cell Transplant. 2009; 18(3):297-304. PMID: 19558778.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  36. Grayson WL, Martens TP, Eng GM, Radisic M, Vunjak-Novakovic G. Biomimetic approach to tissue engineering. Semin Cell Dev Biol. 2009 Aug; 20(6):665-73. PMID: 19146967.
    Citations: 47     Fields:    Translation:HumansAnimals
  37. Karp JM, Yeh J, Eng G, Fukuda J, Blumling J, Suh KY, Cheng J, Mahdavi A, Borenstein J, Langer R, Khademhosseini A. Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip. 2007 Jun; 7(6):786-94. PMID: 17538722.
    Citations: 101     Fields:    Translation:HumansCells
  38. Khademhosseini A, Eng G, Yeh J, Kucharczyk PA, Langer R, Vunjak-Novakovic G, Radisic M. Microfluidic patterning for fabrication of contractile cardiac organoids. Biomed Microdevices. 2007 Apr; 9(2):149-57. PMID: 17146728.
    Citations: 59     Fields:    Translation:AnimalsCells
  39. Khademhosseini A, Eng G, Yeh J, Fukuda J, Blumling J, Langer R, Burdick JA. Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment. J Biomed Mater Res A. 2006 Dec 01; 79(3):522-32. PMID: 16788972.
    Citations: 73     Fields:    Translation:AnimalsCells
  40. Yeh J, Ling Y, Karp JM, Gantz J, Chandawarkar A, Eng G, Blumling J, Langer R, Khademhosseini A. Micromolding of shape-controlled, harvestable cell-laden hydrogels. Biomaterials. 2006 Nov; 27(31):5391-8. PMID: 16828863.
    Citations: 90     Fields:    Translation:AnimalsCells
  41. Fukuda J, Khademhosseini A, Yeo Y, Yang X, Yeh J, Eng G, Blumling J, Wang CF, Kohane DS, Langer R. Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures. Biomaterials. 2006 Oct; 27(30):5259-67. PMID: 16814859.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  42. Fukuda J, Khademhosseini A, Yeh J, Eng G, Cheng J, Farokhzad OC, Langer R. Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components. Biomaterials. 2006 Mar; 27(8):1479-86. PMID: 16242769.
    Citations: 51     Fields:    Translation:AnimalsCells
  43. Khademhosseini A, Yeh J, Eng G, Karp J, Kaji H, Borenstein J, Farokhzad OC, Langer R. Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab Chip. 2005 Dec; 5(12):1380-6. PMID: 16286969.
    Citations: 52     Fields:    
  44. Farokhzad OC, Khademhosseini A, Jon S, Hermmann A, Cheng J, Chin C, Kiselyuk A, Teply B, Eng G, Langer R. Microfluidic system for studying the interaction of nanoparticles and microparticles with cells. Anal Chem. 2005 Sep 01; 77(17):5453-9. PMID: 16131052.
    Citations: 50     Fields:    Translation:HumansCells
  45. Khademhosseini A, Suh KY, Yang JM, Eng G, Yeh J, Levenberg S, Langer R. Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures. Biomaterials. 2004 Aug; 25(17):3583-92. PMID: 15020132.
    Citations: 52     Fields:    Translation:AnimalsCells
  46. Khademhosseini A, Yeh J, Jon S, Eng G, Suh KY, Burdick JA, Langer R. Molded polyethylene glycol microstructures for capturing cells within microfluidic channels. Lab Chip. 2004 Oct; 4(5):425-30. PMID: 15472725.
    Citations: 43     Fields:    Translation:AnimalsCells
  47. Suh KY, Khademhosseini A, Eng G, Langer R. Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying. Langmuir. 2004 Jul 20; 20(15):6080-4. PMID: 15248685.
    Citations: 2     Fields:    
  48. Khademhosseini A, Suh KY, Jon S, Eng G, Yeh J, Chen GJ, Langer R. A soft lithographic approach to fabricate patterned microfluidic channels. Anal Chem. 2004 Jul 01; 76(13):3675-81. PMID: 15228340.
    Citations: 21     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.