Harvard Catalyst Profiles

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Waihay Wong, Ph.D., M.D.

Title
Institution
Department
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Biography
education and training
Duke UniversityB.S.2004
University of PennsylvaniaPh.D2012
University of PennsylvaniaM.D.2014
Brigham and Women's HospitalResidency2017Pathology
Brigham and Women's HospitalFellowship2018Hematopathology

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Agrawal M, Niroula A, Cunin P, McConkey M, Shkolnik V, Kim PG, Wong WJ, Weeks LD, Lin AE, Miller PG, Gibson CJ, Sekar A, Schaefer IM, Neuberg D, Stone RM, Bick AG, Uddin MM, Griffin GK, Jaiswal S, Natarajan P, Nigrovic PA, Rao DA, Ebert BL. TET2-mutant clonal hematopoiesis and risk of gout. Blood. 2022 09 08; 140(10):1094-1103. PMID: 35714308; PMCID: PMC9461470.
    Citations: 2     Fields:    Translation:HumansAnimals
  2. Vining KH, Marneth AE, Adu-Berchie K, Grolman JM, Tringides CM, Liu Y, Wong WJ, Pozdnyakova O, Severgnini M, Stafford A, Duda GN, Hodi FS, Mullally A, Wucherpfennig KW, Mooney DJ. Mechanical checkpoint regulates monocyte differentiation in fibrotic niches. Nat Mater. 2022 08; 21(8):939-950. PMID: 35817965.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  3. Evans MG, Crymes A, Crombie JL, Basu SS, Dillon DA, Wong WJ. Monotypic plasmacytoid cells mimicking lymph node malignancy in the setting of COVID-19 recovery. Am J Hematol. 2022 05; 97(5):666-667. PMID: 34779014; PMCID: PMC8646593.
    Citations: 1     Fields:    Translation:HumansCells
  4. Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, Slabicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, Shin WJ, Pirruccello J, Tsai JM, Agrawal M, Kiel DP, Bouxsein ML, Richards JB, Evans DM, Wein MN, Charles JF, Jaiswal S, Natarajan P, Ebert BL. Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. J Exp Med. 2021 12 06; 218(12). PMID: 34698806; PMCID: PMC8552148.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  5. Niroula A, Sekar A, Murakami MA, Trinder M, Agrawal M, Wong WJ, Bick AG, Uddin MM, Gibson CJ, Griffin GK, Honigberg MC, Zekavat SM, Paruchuri K, Natarajan P, Ebert BL. Distinction of lymphoid and myeloid clonal hematopoiesis. Nat Med. 2021 11; 27(11):1921-1927. PMID: 34663986; PMCID: PMC8621497.
    Citations: 23     Fields:    Translation:HumansCells
  6. Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A, Wong W, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, Nilsson B, Bick AG, Weinstock JS, Miller M, Niroula A, Dunford A, Taylor-Weiner A, Wood T, Barbera A, Anand S, Psaty BM, Desai P, Cho MH, Johnson AD, Loos R, MacArthur DG, Lek M, Neuberg DS, Lage K, Carr SA, Hellstrom-Lindberg E, Malcovati L, Papaemmanuil E, Stewart C, Getz G, Bradley RK, Jaiswal S, Ebert BL. ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021 09; 2(5):500-517. PMID: 34568833; PMCID: PMC8462124.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  7. Miller PG, Sperling AS, Gibson CJ, Pozdnyakova O, Wong WJ, Manos MP, Buchbinder EI, Hodi FS, Ebert BL, Davids MS. A deep molecular response of splenic marginal zone lymphoma to front-line checkpoint blockade. Haematologica. 2021 02 01; 106(2):651-654. PMID: 33054119.
    Citations: 2     Fields:    Translation:Humans
  8. Boettcher S, Miller PG, Sharma R, McConkey M, Leventhal M, Krivtsov AV, Giacomelli AO, Wong W, Kim J, Chao S, Kurppa KJ, Yang X, Milenkowic K, Piccioni F, Root DE, Rücker FG, Flamand Y, Neuberg D, Lindsley RC, Jänne PA, Hahn WC, Jacks T, Döhner H, Armstrong SA, Ebert BL. A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies. Science. 2019 08 09; 365(6453):599-604. PMID: 31395785.
    Citations: 118     Fields:    Translation:HumansAnimalsCells
  9. Patel SS, Ho C, Ptashkin RN, Sadigh S, Bagg A, Geyer JT, Xu ML, Prebet T, Mason EF, Seegmiller AC, Morgan EA, Steensma DP, Winer ES, Wong WJ, Hasserjian RP, Weinberg OK. Clinicopathologic and genetic characterization of nonacute NPM1-mutated myeloid neoplasms. Blood Adv. 2019 05 14; 3(9):1540-1545. PMID: 31085507; PMCID: PMC6517660.
    Citations: 12     Fields:    Translation:Humans
  10. Wong WJ, Wong WJ, Baltay M, Getz A, Fuhrman K, Aster JC, Hasserjian RP, Pozdnyakova O. Gene expression profiling distinguishes prefibrotic from overtly fibrotic myeloproliferative neoplasms and identifies disease subsets with distinct inflammatory signatures. PLoS One. 2019; 14(5):e0216810. PMID: 31071164; PMCID: PMC6534080.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  11. Wong WJ, Wong WJ, Pozdnyakova O. Myeloproliferative neoplasms: Diagnostic workup of the cythemic patient. Int J Lab Hematol. 2019 May; 41 Suppl 1:142-150. PMID: 31069979.
    Citations: 3     Fields:    Translation:Humans
  12. Boiocchi L, Hasserjian RP, Pozdnyakova O, Wong WJ, Wong WJ, Lennerz JK, Le LP, Dias-Santagata D, Iafrate AJ, Hobbs GS, Nardi V. Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms. Hum Pathol. 2019 04; 86:1-11. PMID: 30594750.
    Citations: 12     Fields:    Translation:Humans
  13. Wong WJ, Wong WJ, Ruhangaza D, Manirakiza A, Omondi J, Mugabe MC, Isabelle I, Morgan EA, Aster JC. Concomitant classic Hodgkin lymphoma and schistosomiasis. Am J Hematol. 2019 07; 94(7):840-841. PMID: 30328130.
    Citations:    Fields:    Translation:HumansAnimals
  14. Wong WJ, Hasserjian RP, Pinkus GS, Breyfogle LJ, Mullally A, Pozdnyakova O. JAK2, CALR, MPL and ASXL1 mutational status correlates with distinct histological features in Philadelphia chromosome-negative myeloproliferative neoplasms. Haematologica. 2018 02; 103(2):e63-e68. PMID: 29146710.
    Citations: 9     Fields:    Translation:HumansCells
  15. Gade TPF, Tucker E, Nakazawa MS, Hunt SJ, Wong W, Krock B, Weber CN, Nadolski GJ, Clark TWI, Soulen MC, Furth EE, Winkler JD, Amaravadi RK, Simon MC. Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma. Radiology. 2017 06; 283(3):702-710. PMID: 28253108; PMCID: PMC5452879.
    Citations: 26     Fields:    Translation:AnimalsCells
  16. Naunheim MR, Wong WJ, Carroll TL. Chalky Vocal Fold Lesions. JAMA Otolaryngol Head Neck Surg. 2017 02 01; 143(2):185-186. PMID: 27542104.
    Citations:    Fields:    Translation:Humans
  17. Wong WJ, Wong WJ, Lauria A, Hornick JL, Xiao S, Fletcher JA, Marino-Enriquez A. Alternate PAX3-FOXO1 oncogenic fusion in biphenotypic sinonasal sarcoma. Genes Chromosomes Cancer. 2016 Jan; 55(1):25-9. PMID: 26355893.
    Citations: 22     Fields:    Translation:Humans
  18. Wong WJ, Wong WJ, Richardson T, Seykora JT, Cotsarelis G, Simon MC. Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function. J Invest Dermatol. 2015 Feb; 135(2):454-461. PMID: 24999590; PMCID: PMC4286527.
    Citations: 19     Fields:    Translation:AnimalsCells
  19. Wong WJ, Wong WJ, Qiu B, Nakazawa MS, Qing G, Simon MC. MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death. Mol Cell Biol. 2013 Sep; 33(17):3494-504. PMID: 23816886.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  20. Marzec M, Liu X, Wong W, Yang Y, Pasha T, Kantekure K, Zhang P, Woetmann A, Cheng M, Odum N, Wasik MA. Oncogenic kinase NPM/ALK induces expression of HIF1a mRNA. Oncogene. 2011 Mar 17; 30(11):1372-8. PMID: 21102525.
    Citations: 20     Fields:    Translation:HumansCells
  21. Majmundar AJ, Wong WJ, Wong WJ, Simon MC. Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell. 2010 Oct 22; 40(2):294-309. PMID: 20965423; PMCID: PMC3143508.
    Citations: 1041     Fields:    Translation:HumansAnimalsCells
  22. Wong WJ, Wong WJ, Simon MC. The role of MXI1 in VHL deficient tumorigenesis. Cancer Biol Ther. 2008 Oct; 7(10):1628-9. PMID: 18836305; PMCID: PMC3141207.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  23. Winter-Vann AM, Baron RA, Wong W, dela Cruz J, York JD, Gooden DM, Bergo MO, Young SG, Toone EJ, Casey PJ. A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. Proc Natl Acad Sci U S A. 2005 Mar 22; 102(12):4336-41. PMID: 15784746; PMCID: PMC555472.
    Citations: 74     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.