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Navin Rajput Mahadevan, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Knelson EH, Ivanova EV, Tarannum M, Campisi M, Lizotte PH, Booker MA, Ozgenc I, Noureddine M, Meisenheimer B, Chen M, Piel B, Spicer N, Obua B, Messier CM, Shannon E, Mahadevan NR, Tani T, Schol PJ, Lee-Hassett AM, Zlota A, Vo HV, Ha M, Bertram AA, Han S, Thai TC, Gustafson CE, Venugopal K, Haggerty TJ, Albertson TP, Hartley AV, Eser PO, Li ZH, Cañadas I, Vivero M, De Rienzo A, Richards WG, Abu-Yousif AO, Appleman VA, Gregory RC, Parent A, Lineberry N, Smith EL, Jänne PA, Miret JJ, Tolstorukov MY, Romee R, Paweletz CP, Bueno R, Barbie DA. Activation of Tumor-Cell STING Primes NK-Cell Therapy. Cancer Immunol Res. 2022 08 03; 10(8):947-961. PMID: 35678717; PMCID: PMC9357206.
    Citations: 1     Fields:    
  2. Ricciuti B, Wang X, Alessi JV, Rizvi H, Mahadevan NR, Li YY, Polio A, Lindsay J, Umeton R, Sinha R, Vokes NI, Recondo G, Lamberti G, Lawrence M, Vaz VR, Leonardi GC, Plodkowski AJ, Gupta H, Cherniack AD, Tolstorukov MY, Sharma B, Felt KD, Gainor JF, Ravi A, Getz G, Schalper KA, Henick B, Forde P, Anagnostou V, Jänne PA, Van Allen EM, Nishino M, Sholl LM, Christiani DC, Lin X, Rodig SJ, Hellmann MD, Awad MM. Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels. JAMA Oncol. 2022 08 01; 8(8):1160-1168. PMID: 35708671; PMCID: PMC9204620.
    Citations:    Fields:    
  3. Mahadevan NR, Knelson EH, Wolff JO, Vajdi A, Saigí M, Campisi M, Hong D, Thai TC, Piel B, Han S, Reinhold BB, Duke-Cohan JS, Poitras MJ, Taus LJ, Lizotte PH, Portell A, Quadros V, Santucci AD, Murayama T, Cañadas I, Kitajima S, Akitsu A, Fridrikh M, Watanabe H, Reardon B, Gokhale PC, Paweletz CP, Awad MM, Van Allen EM, Lako A, Wang XT, Chen B, Hong F, Sholl LM, Tolstorukov MY, Pfaff K, Jänne PA, Gjini E, Edwards R, Rodig S, Reinherz EL, Oser MG, Barbie DA. Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity. Cancer Discov. 2021 08; 11(8):1952-1969. PMID: 33707236; PMCID: PMC8338750.
    Citations: 12     Fields:    Translation:HumansAnimals
  4. Sehgal K, Portell A, Ivanova EV, Lizotte PH, Mahadevan NR, Greene JR, Vajdi A, Gurjao C, Teceno T, Taus LJ, Thai TC, Kitajima S, Liu D, Tani T, Noureddine M, Lau CJ, Kirschmeier PT, Liu D, Giannakis M, Jenkins RW, Gokhale PC, Goldoni S, Pinzon-Ortiz M, Hastings WD, Hammerman PS, Miret JJ, Paweletz CP, Barbie DA. Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade. J Clin Invest. 2021 01 19; 131(2). PMID: 33151910; PMCID: PMC7810472.
    Citations: 13     Fields:    Translation:AnimalsCells
  5. Campisi M, Sundararaman SK, Shelton SE, Knelson EH, Mahadevan NR, Yoshida R, Tani T, Ivanova E, Cañadas I, Osaki T, Lee SWL, Thai T, Han S, Piel BP, Gilhooley S, Paweletz CP, Chiono V, Kamm RD, Kitajima S, Barbie DA. Tumor-Derived cGAMP Regulates Activation of the Vasculature. Front Immunol. 2020; 11:2090. PMID: 33013881.
    Citations: 7     Fields:    Translation:HumansCells
  6. Ritter JL, Zhu Z, Thai TC, Mahadevan NR, Mertins P, Knelson EH, Piel BP, Han S, Jaffe JD, Carr SA, Barbie DA, Barbie TU. Phosphorylation of RAB7 by TBK1/IKKe Regulates Innate Immune Signaling in Triple-Negative Breast Cancer. Cancer Res. 2020 01 01; 80(1):44-56. PMID: 31662325; PMCID: PMC6942622.
    Citations: 5     Fields:    Translation:HumansCells
  7. Helgager J, Lidov HG, Mahadevan NR, Kieran MW, Ligon KL, Alexandrescu S. A novel GIT2-BRAF fusion in pilocytic astrocytoma. Diagn Pathol. 2017 Nov 15; 12(1):82. PMID: 29141672.
    Citations: 10     Fields:    Translation:HumansCells
  8. Rodvold JJ, Chiu KT, Hiramatsu N, Nussbacher JK, Galimberti V, Mahadevan NR, Willert K, Lin JH, Zanetti M. Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells. Sci Signal. 2017 Jun 06; 10(482). PMID: 28588081; PMCID: PMC5962022.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  9. Mahadevan NR, Morgan EA, Mitchell RN. Case report and literature review: cardiac tamponade as a complication of pericardial extramedullary hematopoiesis. Cardiovasc Pathol. 2016 Sep-Oct; 25(5):371-4. PMID: 27288747.
    Citations: 2     Fields:    Translation:Humans
  10. Rodvold JJ, Mahadevan NR, Zanetti M. Immune modulation by ER stress and inflammation in the tumor microenvironment. Cancer Lett. 2016 09 28; 380(1):227-36. PMID: 26525580.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  11. Zanetti M, Rodvold JJ, Mahadevan NR. The evolving paradigm of cell-nonautonomous UPR-based regulation of immunity by cancer cells. Oncogene. 2016 Jan 21; 35(3):269-78. PMID: 25893303.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  12. Mahadevan NR, Rodvold JJ, Zanetti M. A Janus-faced role of the unfolded protein response in antitumor immunity. Oncoimmunology. 2013 May 01; 2(5):e23901. PMID: 23762789.
    Citations: 3     Fields:    
  13. Mahadevan NR, Zanetti M. Sensing hyperploidy and immune surveillance: a pas-de-deux. Cell Cycle. 2013 Feb 15; 12(4):544-5. PMID: 23370385.
    Citations:    Fields:    Translation:Animals
  14. Mahadevan NR, Anufreichik V, Rodvold JJ, Chiu KT, Sepulveda H, Zanetti M. Cell-extrinsic effects of tumor ER stress imprint myeloid dendritic cells and impair CD8? T cell priming. PLoS One. 2012; 7(12):e51845. PMID: 23272178.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  15. Tumaneng K, Schlegelmilch K, Russell RC, Yimlamai D, Basnet H, Mahadevan N, Fitamant J, Bardeesy N, Camargo FD, Guan KL. YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29. Nat Cell Biol. 2012 Dec; 14(12):1322-9. PMID: 23143395; PMCID: PMC4019071.
    Citations: 245     Fields:    Translation:HumansAnimalsCells
  16. Kumandan S, Mahadevan NR, Chiu K, DeLaney A, Zanetti M. Activation of the unfolded protein response bypasses trastuzumab-mediated inhibition of the PI-3K pathway. Cancer Lett. 2013 Feb 28; 329(2):236-42. PMID: 23200669; PMCID: PMC4091625.
    Citations: 9     Fields:    Translation:HumansCells
  17. Zanetti M, Mahadevan NR. Cancer. Immune surveillance from chromosomal chaos? Science. 2012 Sep 28; 337(6102):1616-7. PMID: 23019639.
    Citations: 4     Fields:    Translation:HumansAnimals
  18. Rodvold JJ, Mahadevan NR, Zanetti M. Lipocalin 2 in cancer: when good immunity goes bad. Cancer Lett. 2012 Mar 28; 316(2):132-8. PMID: 22075378.
    Citations: 48     Fields:    Translation:HumansAnimals
  19. Mahadevan NR, Zanetti M. Tumor stress inside out: cell-extrinsic effects of the unfolded protein response in tumor cells modulate the immunological landscape of the tumor microenvironment. J Immunol. 2011 Nov 01; 187(9):4403-9. PMID: 22013206.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  20. Mahadevan NR, Rodvold J, Almanza G, Pérez AF, Wheeler MC, Zanetti M. ER stress drives Lipocalin 2 upregulation in prostate cancer cells in an NF-?B-dependent manner. BMC Cancer. 2011 Jun 07; 11:229. PMID: 21649922.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  21. Mahadevan NR, Rodvold J, Sepulveda H, Rossi S, Drew AF, Zanetti M. Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6561-6. PMID: 21464300; PMCID: PMC3081038.
    Citations: 125     Fields:    Translation:AnimalsCells
  22. Mahadevan NR, Fernandez A, Rodvold JJ, Almanza G, Zanetti M. Prostate cancer cells undergoing ER stress in vitro and in vivo activate transcription of pro-inflammatory cytokines. J Inflamm Res. 2010; 3:99-103. PMID: 22096360.
    Citations: 8     
  23. Horton AC, Mahadevan NR, Minguillon C, Osoegawa K, Rokhsar DS, Ruvinsky I, de Jong PJ, Logan MP, Gibson-Brown JJ. Conservation of linkage and evolution of developmental function within the Tbx2/3/4/5 subfamily of T-box genes: implications for the origin of vertebrate limbs. Dev Genes Evol. 2008 Dec; 218(11-12):613-28. PMID: 18815807.
    Citations: 26     Fields:    Translation:HumansAnimals
  24. Mahadevan NR, Horton AC, Gibson-Brown JJ. Developmental expression of the amphioxus Tbx1/ 10 gene illuminates the evolution of vertebrate branchial arches and sclerotome. Dev Genes Evol. 2004 Nov; 214(11):559-66. PMID: 15372236.
    Citations: 16     Fields:    Translation:AnimalsCells
  25. Horton AC, Mahadevan NR, Ruvinsky I, Gibson-Brown JJ. Phylogenetic analyses alone are insufficient to determine whether genome duplication(s) occurred during early vertebrate evolution. J Exp Zool B Mol Dev Evol. 2003 Oct 15; 299(1):41-53. PMID: 14508816.
    Citations: 10     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.