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Last Name

profileMin Dong, Ph.D.

TitleAssistant Professor of Surgery
InstitutionBoston Children's Hospital
AddressChildren's Hospital
Dept. of Urology, En 1070
300 Longwood Ave
Boston MA 02115
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R21NS082830     (DONG, MIN)Sep 30, 2013 - Aug 31, 2015
Next generation of botulinum neurotoxins with enhanced binding to human receptors
Role: Principal Investigator

R01NS080833     (DONG, MIN)Mar 1, 2013 - Feb 28, 2018
Long-term effects of botulinum neurotoxins on neuronal viability
Role: Principal Investigator

R56AI097834     (DONG, MIN)Aug 20, 2012 - Aug 19, 2014
Cytotoxicity of botulinum neurotoxins
Role: Principal Investigator

P51RR000168     (FLIER, JEFFREY S)Jun 1, 1978 - Apr 30, 2013
New England Primate Research Center Base Grant
Role: Co-Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Tao L, Peng L, Berntsson RP, Liu SM, Park S, Yu F, Boone C, Palan S, Beard M, Chabrier PE, Stenmark P, Krupp J, Dong M. Engineered botulinum neurotoxin B with improved efficacy for targeting human receptors. Nat Commun. 2017 Jul 03; 8(1):53. PMID: 28674381.
    View in: PubMed
  2. Ma Y, Yang AC, Duan Y, Dong M, Yeung AS. Quality and readability of online information resources on insomnia. Front Med. 2017 May 13. PMID: 28500432.
    View in: PubMed
  3. Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, Zhang X, Stallcup WB, Miao J, He X, Hurdle JG, Breault DT, Brass AL, Dong M. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature. 2016 Oct 20; 538(7625):350-355. PMID: 27680706.
    View in: PubMed
  4. Peng L, Adler M, Demogines A, Borrell A, Liu H, Tao L, Tepp WH, Zhang SC, Johnson EA, Sawyer SL, Dong M. Widespread sequence variations in VAMP1 across vertebrates suggest a potential selective pressure from botulinum neurotoxins. PLoS Pathog. 2014 Jul; 10(7):e1004177. PMID: 25010769; PMCID: PMC4092145.
  5. Lü J, Yang J, Dong M, Sahin O. Nanomechanical spectroscopy of synthetic and biological membranes. Nanoscale. 2014 Jul 07; 6(13):7604-8. PMID: 24895687.
    View in: PubMed
  6. Zhang Z, Song J, Besenbacher F, Dong M, Gothelf KV. Self-assembly of DNA origami and single-stranded tile structures at room temperature. Angew Chem Int Ed Engl. 2013 Aug 26; 52(35):9219-23. PMID: 23843201.
    View in: PubMed
  7. Song J, Zhang Z, Zhang S, Liu L, Li Q, Xie E, Gothelf KV, Besenbacher F, Dong M. Isothermal hybridization kinetics of DNA assembly of two-dimensional DNA origami. Small. 2013 Sep 09; 9(17):2954-9. PMID: 23436715.
    View in: PubMed
  8. Zhang S, Andreasen M, Nielsen JT, Liu L, Nielsen EH, Song J, Ji G, Sun F, Skrydstrup T, Besenbacher F, Nielsen NC, Otzen DE, Dong M. Coexistence of ribbon and helical fibrils originating from hIAPP(20-29) revealed by quantitative nanomechanical atomic force microscopy. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):2798-803. PMID: 23388629; PMCID: PMC3581879.
  9. Peng L, Liu H, Ruan H, Tepp WH, Stoothoff WH, Brown RH, Johnson EA, Yao WD, Zhang SC, Dong M. Cytotoxicity of botulinum neurotoxins reveals a direct role of syntaxin 1 and SNAP-25 in neuron survival. Nat Commun. 2013; 4:1472. PMID: 23403573; PMCID: PMC4052923.
  10. Pfeffer C, Larsen S, Song J, Dong M, Besenbacher F, Meyer RL, Kjeldsen KU, Schreiber L, Gorby YA, El-Naggar MY, Leung KM, Schramm A, Risgaard-Petersen N, Nielsen LP. Filamentous bacteria transport electrons over centimetre distances. Nature. 2012 Nov 08; 491(7423):218-21. PMID: 23103872.
    View in: PubMed
  11. Song J, Arbona JM, Zhang Z, Liu L, Xie E, Elezgaray J, Aime JP, Gothelf KV, Besenbacher F, Dong M. Direct visualization of transient thermal response of a DNA origami. J Am Chem Soc. 2012 Jun 20; 134(24):9844-7. PMID: 22646845.
    View in: PubMed
  12. Chen M, Gao S, Dong M, Song J, Yang C, Howard KA, Kjems J, Besenbacher F. Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery. ACS Nano. 2012 Jun 26; 6(6):4835-44. PMID: 22621383.
    View in: PubMed
  13. Peng L, Berntsson RP, Tepp WH, Pitkin RM, Johnson EA, Stenmark P, Dong M. Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins. J Cell Sci. 2012 Jul 01; 125(Pt 13):3233-42. PMID: 22454523; PMCID: PMC4067266.
  14. Song J, Kahveci D, Chen M, Guo Z, Xie E, Xu X, Besenbacher F, Dong M. Enhanced catalytic activity of lipase encapsulated in PCL nanofibers. Langmuir. 2012 Apr 10; 28(14):6157-62. PMID: 22397625.
    View in: PubMed
  15. Song J, Chen M, Olesen MB, Wang C, Havelund R, Li Q, Xie E, Yang R, Bøggild P, Wang C, Besenbacher F, Dong M. Direct electrospinning of Ag/polyvinylpyrrolidone nanocables. Nanoscale. 2011 Dec; 3(12):4966-71. PMID: 21989684.
    View in: PubMed
  16. Peng L, Tepp WH, Johnson EA, Dong M. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors. PLoS Pathog. 2011 Mar; 7(3):e1002008. PMID: 21483489; PMCID: PMC3068998.
  17. Dong M, Sahin O. A nanomechanical interface to rapid single-molecule interactions. Nat Commun. 2011; 2:247. PMID: 21427718.
    View in: PubMed
  18. Liu H, Tørring T, Dong M, Rosen CB, Besenbacher F, Gothelf KV. DNA-templated covalent coupling of G4 PAMAM dendrimers. J Am Chem Soc. 2010 Dec 29; 132(51):18054-6. PMID: 21133363.
    View in: PubMed
  19. Michelow IC, Dong M, Mungall BA, Yantosca LM, Lear C, Ji X, Karpel M, Rootes CL, Brudner M, Houen G, Eisen DP, Kinane TB, Takahashi K, Stahl GL, Olinger GG, Spear GT, Ezekowitz RA, Schmidt EV. A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus. J Biol Chem. 2010 Aug 06; 285(32):24729-39. PMID: 20516066; PMCID: PMC2915709.
  20. Dong M, Husale S, Sahin O. Determination of protein structural flexibility by microsecond force spectroscopy. Nat Nanotechnol. 2009 Aug; 4(8):514-7. PMID: 19662014.
    View in: PubMed
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