Christina Louise Costantino, M.D.
This page shows the publications Christina Costantino has written about Antimetabolites, Antineoplastic.
The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase. Cancer Res. 2009 Jun 01; 69(11):4567-72.
Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence. Cancer Res. 2009 Feb 01; 69(3):984-91.
pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs. PLoS One. 2010 Nov 29; 5(11):e15455.
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