Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Christina Louise Costantino, M.D.

Profile Picture

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F32CA221103 (COSTANTINO, CHRISTINA L) Jul 1, 2017 - Jun 30, 2019
    Circulating tumor cells (CTCs) in EGFR-mutant human lung cancer
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Reinicke T, Costantino CL, Anderson DJ, Tran J, Griggs C. A Network of Anomalies Prompting VACTERL Workup in a Trisomy 21 Newborn. Cureus. 2022 Jan; 14(1):e21290. PMID: 35186552; PMCID: PMC8846374.
    Citations: 1     
  2. Costantino CL, Wright CD. Extended Pulmonary Resection by Sleeve Lobectomy and Carinal Pneumonectomy: Selection and Technique. Thorac Surg Clin. 2021 Aug; 31(3):273-281. PMID: 34304835.
    Citations:    Fields:    Translation:Humans
  3. Costantino CL, Schumacher LY. Surgical Technique: Minimally Invasive First-Rib Resection. Thorac Surg Clin. 2021 Feb; 31(1):81-87. PMID: 33220774.
    Citations:    Fields:    Translation:Humans
  4. Li SS, Klempner SJ, Costantino CL, Parikh A, Clark JW, Wo JY, Hong TS, Mullen JT. Impact of Treatment Sequencing on Survival for Patients with Locally Advanced Gastric Cancer. Ann Surg Oncol. 2021 May; 28(5):2856-2865. PMID: 33393043.
    Citations: 2     Fields:    Translation:Humans
  5. Surface LE, Burrow DT, Li J, Park J, Kumar S, Lyu C, Song N, Yu Z, Rajagopal A, Bae Y, Lee BH, Mumm S, Gu CC, Baker JC, Mohseni M, Sum M, Huskey M, Duan S, Bijanki VN, Civitelli R, Gardner MJ, McAndrew CM, Ricci WM, Gurnett CA, Diemer K, Wan F, Costantino CL, Shannon KM, Raje N, Dodson TB, Haber DA, Carette JE, Varadarajan M, Brummelkamp TR, Birsoy K, Sabatini DM, Haller G, Peterson TR. ATRAID regulates the action of nitrogen-containing bisphosphonates on bone. Sci Transl Med. 2020 05 20; 12(544). PMID: 32434850; PMCID: PMC7882121.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  6. Costantino CL, Geller AD, Visenio MR, Morse CR, Rattner DW. Outcomes of Laparoscopic Heller Myotomy for Achalasia: 22-Year Experience. J Gastrointest Surg. 2020 06; 24(6):1411-1416. PMID: 32300963.
    Citations: 3     Fields:    Translation:Humans
  7. Chabon JJ, Hamilton EG, Kurtz DM, Esfahani MS, Moding EJ, Stehr H, Schroers-Martin J, Nabet BY, Chen B, Chaudhuri AA, Liu CL, Hui AB, Jin MC, Azad TD, Almanza D, Jeon YJ, Nesselbush MC, Co Ting Keh L, Bonilla RF, Yoo CH, Ko RB, Chen EL, Merriott DJ, Massion PP, Mansfield AS, Jen J, Ren HZ, Lin SH, Costantino CL, Burr R, Tibshirani R, Gambhir SS, Berry GJ, Jensen KC, West RB, Neal JW, Wakelee HA, Loo BW, Kunder CA, Leung AN, Lui NS, Berry MF, Shrager JB, Nair VS, Haber DA, Sequist LV, Alizadeh AA, Diehn M. Integrating genomic features for non-invasive early lung cancer detection. Nature. 2020 04; 580(7802):245-251. PMID: 32269342.
    Citations: 134     Fields:    Translation:Humans
  8. McKinley SK, Wang LJ, Gartland RM, Westfal ML, Costantino CL, Schwartz D, Merrill AL, Petrusa E, Lillemoe K, Phitayakorn R. "Yes, I'm the Doctor": One Department's Approach to Assessing and Addressing Gender-Based Discrimination in the Modern Medical Training Era. Acad Med. 2019 11; 94(11):1691-1698. PMID: 31274522.
    Citations: 13     Fields:    Translation:Humans
  9. Li SS, Costantino CL, Mullen JT. Morbidity and Mortality of Total Gastrectomy: a Comprehensive Analysis of 90-Day Outcomes. J Gastrointest Surg. 2019 07; 23(7):1340-1348. PMID: 31062268.
    Citations: 7     Fields:    Translation:Humans
  10. Li SS, Costantino CL, Rattner DW, Mullen JT. Outcomes of Extended Lymphadenectomy for Gastroesophageal Carcinoma: A Large Western Series. J Am Coll Surg. 2019 06; 228(6):879-891. PMID: 30825638.
    Citations: 1     Fields:    Translation:Humans
  11. Costantino CL, Mullen JT. Minimally Invasive Gastric Cancer Surgery. Surg Oncol Clin N Am. 2019 04; 28(2):201-213. PMID: 30851823.
    Citations: 9     Fields:    Translation:Humans
  12. Costantino CL, Geller AD, Wright CD, Ott HC, Muniappan A, Mathisen DJ, Lanuti M. Carinal surgery: A single-institution experience spanning 2 decades. J Thorac Cardiovasc Surg. 2019 05; 157(5):2073-2083.e1. PMID: 30709673.
    Citations: 13     Fields:    Translation:Humans
  13. Costantino CL, Niles JL, Wright CD, Mathisen DJ, Muniappan A. Subglottic Stenosis in Granulomatosis With Polyangiitis: The Role of Laryngotracheal Resection. Ann Thorac Surg. 2018 Jan; 105(1):249-253. PMID: 29100647.
    Citations: 1     Fields:    Translation:Humans
  14. Costantino CL, Mathisen DJ. Idiopathic laryngotracheal stenosis. J Thorac Dis. 2016 Mar; 8(Suppl 2):S204-9. PMID: 26981272; PMCID: PMC4775268.
    Citations: 8     
  15. Twerdahl EH, Costantino CL, Ferrone CR, Hodin RA. Primary Hepatic Gastrinoma. J Gastrointest Surg. 2016 Mar; 20(3):662-3. PMID: 26556475.
    Citations: 3     Fields:    
  16. Costantino CL, Winter JM, Yeo CJ, Cowan SW. Alton Ochsner, MD (1896-1981): surgical pioneer and legacy linking smoking and disease. Am Surg. 2015 Jun; 81(6):547-9. PMID: 26031264.
    Citations:    Fields:    
  17. Williams TK, Costantino CL, Bildzukewicz NA, Richards NG, Rittenhouse DW, Einstein L, Cozzitorto JA, Keen JC, Dasgupta A, Gorospe M, Gonye GE, Yeo CJ, Witkiewicz AK, Brody JR. pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs. PLoS One. 2010 Nov 29; 5(11):e15455. PMID: 21152064.
    Citations: 29     Fields:    Translation:HumansCells
  18. Showalter SL, Wang Z, Costantino CL, Witkiewicz AK, Yeo CJ, Brody JR, Carr BI. Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway. J Gastroenterol Hepatol. 2010 Apr; 25(4):738-44. PMID: 19929921.
    Citations: 17     Fields:    Translation:HumansCells
  19. Brody JR, Costantino CL, Berger AC, Sato T, Lisanti MP, Yeo CJ, Emmons RV, Witkiewicz AK. Expression of indoleamine 2,3-dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival. Cell Cycle. 2009 Jun 15; 8(12):1930-4. PMID: 19448397.
    Citations: 72     Fields:    Translation:HumansCells
  20. Costantino CL, Witkiewicz AK, Kuwano Y, Cozzitorto JA, Kennedy EP, Dasgupta A, Keen JC, Yeo CJ, Gorospe M, Brody JR. The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase. Cancer Res. 2009 Jun 01; 69(11):4567-72. PMID: 19487279.
    Citations: 92     Fields:    Translation:HumansCells
  21. Witkiewicz AK, Costantino CL, Metz R, Muller AJ, Prendergast GC, Yeo CJ, Brody JR. Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target. J Am Coll Surg. 2009 May; 208(5):781-7; discussion 787-9. PMID: 19476837; PMCID: PMC3176891.
    Citations: 55     Fields:    Translation:HumansCells
  22. Brody JR, Costantino CL, Potoczek M, Cozzitorto J, McCue P, Yeo CJ, Hruban RH, Witkiewicz AK. Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma. Mod Pathol. 2009 May; 22(5):651-9. PMID: 19270646.
    Citations: 31     Fields:    Translation:Humans
  23. Brody JR, Hucl T, Costantino CL, Eshleman JR, Gallmeier E, Zhu H, van der Heijden MS, Winter JM, Wikiewicz AK, Yeo CJ, Kern SE. Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence. Cancer Res. 2009 Feb 01; 69(3):984-91. PMID: 19155291.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  24. Showalter SL, Huang YH, Witkiewicz A, Costantino CL, Yeo CJ, Green JJ, Langer R, Anderson DG, Sawicki JA, Brody JR. Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells. Cancer Biol Ther. 2008 Oct; 7(10):1584-90. PMID: 19039293; PMCID: PMC3218426.
    Citations: 23     Fields:    Translation:HumansCells
  25. Hostetter C, Licata LA, Witkiewicz A, Costantino CL, Yeo CJ, Brody JR, Keen JC. Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells. Cancer Biol Ther. 2008 Sep; 7(9):1496-506. PMID: 18769129.
    Citations: 48     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Costantino's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (156)
Co-Authors (26)
Similar People (60)
Same Department 
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.