Harvard Catalyst Profiles

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Sudeshna Das, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yusuf R, Saez B, Sharda A, van Gastel N, Yu V, Baryawno N, Scadden EW, Acharya SS, Chattophadhyay S, Huang C, Viswanathan V, S'aulis D, Cobert J, Sykes DB, Keibler MA, Das S, Hutchinson JN, Churchill M, Mukherjee S, Lee D, Mercier FE, Doench J, Bullinger L, Logan DJ, Schreiber S, Stephanopoulos G, Rizzo WB, Scadden DT. Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers. Blood. 2020 May 26. PMID: 32458004.
  2. Calvo-Rodriguez M, Hou SS, Snyder AC, Kharitonova EK, Russ AN, Das S, Fan Z, Muzikansky A, Garcia-Alloza M, Serrano-Pozo A, Hudry E, Bacskai BJ. Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease. Nat Commun. 2020 May 01; 11(1):2146. PMID: 32358564.
  3. Gui Y, Marks JD, Das S, Hyman BT, Serrano-Pozo A. Characterization of the 18 kDa translocator protein (TSPO) expression in post-mortem normal and Alzheimer's disease brains. Brain Pathol. 2020 01; 30(1):151-164. PMID: 31276244.
  4. Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B. The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aß Plaques. Cell Rep. 2019 04 23; 27(4):1293-1306.e6. PMID: 31018141.
  5. Bihlmeyer NA, Merrill E, Lambert Y, Srivastava GP, Clark TW, Hyman BT, Das S. Novel methods for integration and visualization of genomics and genetics data in Alzheimer's disease. Alzheimers Dement. 2019 06; 15(6):788-798. PMID: 30935898.
  6. Zhou B, Kreuzer J, Kumsta C, Wu L, Kamer KJ, Cedillo L, Zhang Y, Li S, Kacergis MC, Webster CM, Fejes-Toth G, Naray-Fejes-Toth A, Das S, Hansen M, Haas W, Soukas AA. Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension. Cell. 2019 04 04; 177(2):299-314.e16. PMID: 30929899.
  7. Das S, Rogan M, Kawadler H, Brin S, Corlosquet S, Clark T. Workshop on The Future of the Web for Collaborative Science (FWCS 2010), WWW2010. PD Online: A case study in scientific collaboration on the web. 2018. View Publication.
  8. Antoury L, Hu N, Balaj L, Das S, Georghiou S, Darras B, Clark T, Breakefield XO, Wheeler TM. Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies. Nat Commun. 2018 09 25; 9(1):3906. PMID: 30254196.
    Citations:    Fields:    Translation:HumansAnimalsCells
  9. Hopp SC, Bihlmeyer NA, Corradi JP, Vanderburg C, Cacace AM, Das S, Clark TW, Betensky RA, Hyman BT, Hudry E. Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain. J Neurochem. 2018 10; 147(1):24-39. PMID: 29806693.
    Citations:    Fields:    
  10. Das S, Mishra KP, Ganju L, Singh SB. Intranasally delivered small interfering RNA-mediated suppression of scavenger receptor Mac-1 attenuates microglial phenotype switching and working memory impairment following hypoxia. Neuropharmacology. 2018 07 15; 137:240-255. PMID: 29738851.
  11. Bennett RE, Robbins AB, Hu M, Cao X, Betensky RA, Clark T, Das S, Hyman BT. Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease. Proc Natl Acad Sci U S A. 2018 02 06; 115(6):E1289-E1298. PMID: 29358399.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  12. Ofengeim D, Mazzitelli S, Ito Y, DeWitt JP, Mifflin L, Zou C, Das S, Adiconis X, Chen H, Zhu H, Kelliher MA, Levin JZ, Yuan J. RIPK1 mediates a disease-associated microglial response in Alzheimer's disease. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):E8788-E8797. PMID: 28904096.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  13. Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS. Science. 2016 Aug 05; 353(6299):603-8. PMID: 27493188.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  14. Allen GI, Amoroso N, Anghel C, Balagurusamy V, Bare CJ, Beaton D, Bellotti R, Bennett DA, Boehme KL, Boutros PC, Caberlotto L, Caloian C, Campbell F, Chaibub Neto E, Chang YC, Chen B, Chen CY, Chien TY, Clark T, Das S, Davatzikos C, Deng J, Dillenberger D, Dobson RJ, Dong Q, Doshi J, Duma D, Errico R, Erus G, Everett E, Fardo DW, Friend SH, Fröhlich H, Gan J, St George-Hyslop P, Ghosh SS, Glaab E, Green RC, Guan Y, Hong MY, Huang C, Hwang J, Ibrahim J, Inglese P, Iyappan A, Jiang Q, Katsumata Y, Kauwe JS, Klein A, Kong D, Krause R, Lalonde E, Lauria M, Lee E, Lin X, Liu Z, Livingstone J, Logsdon BA, Lovestone S, Ma TW, Malhotra A, Mangravite LM, Maxwell TJ, Merrill E, Nagorski J, Namasivayam A, Narayan M, Naz M, Newhouse SJ, Norman TC, Nurtdinov RN, Oyang YJ, Pawitan Y, Peng S, Peters MA, Piccolo SR, Praveen P, Priami C, Sabelnykova VY, Senger P, Shen X, Simmons A, Sotiras A, Stolovitzky G, Tangaro S, Tateo A, Tung YA, Tustison NJ, Varol E, Vradenburg G, Weiner MW, Xiao G, Xie L, Xie Y, Xu J, Yang H, Zhan X, Zhou Y, Zhu F, Zhu H, Zhu S. Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease. Alzheimers Dement. 2016 06; 12(6):645-53. PMID: 27079753.
    Citations: 9     Fields:    Translation:Humans
  15. Merrill E, Corlosquet S, Ciccarese P, Clark T, Das S. Semantic Web repositories for genomics data using the eXframe platform. J Biomed Semantics. 2014; 5(Suppl 1 Proceedings of the Bio-Ontologies Spec Interest G):S3. PMID: 25093072.
    Citations: 2     Fields:    
  16. Das S, McCaffrey PG, Talkington MW, Andrews NA, Corlosquet S, Ivinson AJ, Clark T. Pain Research Forum: application of scientific social media frameworks in neuroscience. Front Neuroinform. 2014; 8:21. PMID: 24653693.
    Citations: 2     
  17. Merrill E, Corlosquet S, Ciccarese P, Clark T and Das S. Bio-Ontologies 2013. eXframe: A Semantic Web Platform for Genomics Experiments. 2013. View Publication.
  18. Ho Sui S, Merrill E, Gehlenborg N, Haseley P, Sytchev I, Park R, Rocca-Serra P, Corlosquet S, Gonzalez-Beltran A, Maguire E, Hofmann O, Park P, Das S, Sansone SA, Hide W. The Stem Cell Commons: an exemplar for data integration in the biomedical domain driven by the ISA framework. AMIA Jt Summits Transl Sci Proc. 2013; 2013:70. PMID: 24303302.
    Citations: 1     
  19. McFarland KN, Das S, Sun TT, Leyfer D, Kim MO, Xia E, Sangrey GR, Kuhn A, Luthi-Carter R, Clark TW, Sadri-Vakili G, Cha JH. Genome-wide increase in histone H2A ubiquitylation in a mouse model of Huntington's disease. J Huntingtons Dis. 2013; 2(3):263-77. PMID: 25062675.
    Citations: 2     Fields:    Translation:AnimalsCells
  20. McFarland KN, Das S, Sun TT, Leyfer D, Xia E, Sangrey GR, Kuhn A, Luthi-Carter R, Clark TW, Sadri-Vakili G, Cha JH. Genome-wide histone acetylation is altered in a transgenic mouse model of Huntington's disease. PLoS One. 2012; 7(7):e41423. PMID: 22848491.
    Citations: 18     Fields:    Translation:AnimalsCells
  21. Deus HF, Prud'hommeaux E, Miller M, Zhao J, Malone J, Adamusiak T, McCusker J, Das S, Rocca Serra P, Fox R, Marshall MS. Translating standards into practice - one Semantic Web API for Gene Expression. J Biomed Inform. 2012 Aug; 45(4):782-94. PMID: 22449719.
    Citations: 2     Fields:    Translation:Humans
  22. Sansone SA, Rocca-Serra P, Field D, Maguire E, Taylor C, Hofmann O, Fang H, Neumann S, Tong W, Amaral-Zettler L, Begley K, Booth T, Bougueleret L, Burns G, Chapman B, Clark T, Coleman LA, Copeland J, Das S, de Daruvar A, de Matos P, Dix I, Edmunds S, Evelo CT, Forster MJ, Gaudet P, Gilbert J, Goble C, Griffin JL, Jacob D, Kleinjans J, Harland L, Haug K, Hermjakob H, Ho Sui SJ, Laederach A, Liang S, Marshall S, McGrath A, Merrill E, Reilly D, Roux M, Shamu CE, Shang CA, Steinbeck C, Trefethen A, Williams-Jones B, Wolstencroft K, Xenarios I, Hide W. Toward interoperable bioscience data. Nat Genet. 2012 Jan 27; 44(2):121-6. PMID: 22281772.
    Citations: 88     Fields:    
  23. Sinha AU, Merrill E, Armstrong SA, Clark TW, Das S. eXframe: reusable framework for storage, analysis and visualization of genomics experiments. BMC Bioinformatics. 2011 Nov 21; 12:452. PMID: 22103807.
    Citations: 3     Fields:    Translation:HumansCells
  24. Ciccarese P, Ocana M, Garcia Castro LJ, Das S, Clark T. An open annotation ontology for science on web 3.0. J Biomed Semantics. 2011 May 17; 2 Suppl 2:S4. PMID: 21624159.
    Citations: 22     Fields:    
  25. Ciccarese P, Ocana M, Das S, Clark T. Bio-Ontologies 2010: Semantic Applications in Life Sciences. AO: An Open Annotation Ontology for Science on the Web. 2010.
  26. Das S, Goetz M, Girard L, Clark T. ELPUB 2009. 13th International Conference on Electronic Publishing: Rethinking Electronic Publishing: Innovation in Communication Paradigms and Technologies. Scientific Publications on Web 3.0. 2009. View Publication.
  27. Das S, Girard L, Green T, Weitzman L, Lewis-Bowen A, Clark T. Building biomedical web communities using a semantically aware content management system. Brief Bioinform. 2009 Mar; 10(2):129-38. PMID: 19060302.
    Citations: 4     Fields:    Translation:Humans
  28. Das S, Green T, Weitzman L, Lewis-Bowen A, Clark T. Workshop on Health Care and Life Sciences Data Integration for the Semantic Web, WWW2008. Linked data in a scientific collaboration framework. 2008. View Publication.
  29. Chakravarty A, Bowman D, Ecsedy JA, Rabino C, Donovan J, D’Amore N, Veiby P, Rolfe M, and Das S. High Content Screening: Science, Techniques and Applications. Steven A. Haney (Editor). Developing Robust High Content Assays. 2008.
  30. Nagl SB, Das S, Smith TF. Prediction of interaction partners for orphan nuclear receptors by prior-based protein sequence profiles. J Mol Recognit. 2000 May-Jun; 13(3):117-26. PMID: 10867707.
    Citations:    Fields:    Translation:AnimalsCells
  31. Das S, Smith TF. Identifying nature's protein Lego set. Adv Protein Chem. 2000; 54:159-83. PMID: 10829228.
    Citations: 6     Fields:    Translation:Cells
  32. Das S, Yu L, Gaitatzes C, Rogers R, Freeman J, Bienkowska J, Adams RM, Smith TF, Lindelien J. Biology's new Rosetta stone. Nature. 1997 Jan 02; 385(6611):29-30. PMID: 8985242.
    Citations: 20     Fields:    Translation:AnimalsCells
  33. Adams RM, Das S, Smith TF. Multiple domain protein diagnostic patterns. Protein Sci. 1996 Jul; 5(7):1240-9. PMID: 8819157.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.