Harvard Catalyst Profiles

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Robert Mealer, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Suttapitugsakul S, Stavenhagen K, Donskaya S, Bennett DA, Mealer RG, Seyfried NT, Cummings RD. Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain. Mol Cell Proteomics. 2022 Oct 27; 21(12):100433. PMID: 36309312.
    Citations:    Fields:    
  2. Noel M, Chasman DI, Mora S, Otvos JD, Palmer CD, Parsons PJ, Smoller JW, Cummings RD, Mealer RG. The Inflammation Biomarker GlycA Reflects Plasma N-Glycan Branching. Clin Chem. 2022 Oct 18. PMID: 36254612.
    Citations:    Fields:    
  3. Mealer RG, Williams SE, Noel M, Yang B, D'Souza AK, Nakata T, Graham DB, Creasey EA, Cetinbas M, Sadreyev RI, Scolnick EM, Woo CM, Smoller JW, Xavier RJ, Cummings RD. The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain. Mol Psychiatry. 2022 03; 27(3):1405-1415. PMID: 35260802; PMCID: PMC9106890.
    Citations:    Fields:    Translation:AnimalsCells
  4. Williams SE, Noel M, Lehoux S, Cetinbas M, Xavier RJ, Sadreyev RI, Scolnick EM, Smoller JW, Cummings RD, Mealer RG. Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues. Nat Commun. 2022 01 12; 13(1):275. PMID: 35022400; PMCID: PMC8755730.
    Citations: 2     Fields:    Translation:AnimalsCells
  5. Park JH, Reunert J, He M, Mealer RG, Noel M, Wada Y, Grüneberg M, Horváth J, Cummings RD, Schwartz O, Marquardt T. L-Fucose treatment of FUT8-CDG. Mol Genet Metab Rep. 2020 Dec; 25:100680. PMID: 33312876; PMCID: PMC7719959.
    Citations: 3     
  6. Park JH, Mealer RG, Elias AF, Hoffmann S, Grüneberg M, Biskup S, Fobker M, Haven J, Mangels U, Reunert J, Rust S, Schoof J, Schwanke C, Smoller JW, Cummings RD, Marquardt T. N-glycome analysis detects dysglycosylation missed by conventional methods in SLC39A8 deficiency. J Inherit Metab Dis. 2020 11; 43(6):1370-1381. PMID: 32852845.
    Citations: 3     Fields:    Translation:HumansCells
  7. Mealer RG, Jenkins BG, Chen CY, Daly MJ, Ge T, Lehoux S, Marquardt T, Palmer CD, Park JH, Parsons PJ, Sackstein R, Williams SE, Cummings RD, Scolnick EM, Smoller JW. The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation. Sci Rep. 2020 08 04; 10(1):13162. PMID: 32753748.
    Citations: 16     Fields:    Translation:HumansCells
  8. Williams SE, Mealer RG, Scolnick EM, Smoller JW, Cummings RD. Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies. Mol Psychiatry. 2020 12; 25(12):3198-3207. PMID: 32404945.
    Citations: 8     Fields:    Translation:HumansCells
  9. Mealer RG, Williams SE, Daly MJ, Scolnick EM, Cummings RD, Smoller JW. Glycobiology and schizophrenia: a biological hypothesis emerging from genomic research. Mol Psychiatry. 2020 12; 25(12):3129-3139. PMID: 32377000.
    Citations: 12     Fields:    Translation:Humans
  10. Mealer RG, Murray AJ, Shahani N, Subramaniam S, Snyder SH. Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy. J Biol Chem. 2014 Feb 07; 289(6):3547-54. PMID: 24324270; PMCID: PMC3916556.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  11. Mealer RG, Subramaniam S, Snyder SH. Rhes deletion is neuroprotective in the 3-nitropropionic acid model of Huntington's disease. J Neurosci. 2013 Feb 27; 33(9):4206-10. PMID: 23447628.
    Citations: 24     Fields:    Translation:Animals
  12. Subramaniam S, Napolitano F, Mealer RG, Kim S, Errico F, Barrow R, Shahani N, Tyagi R, Snyder SH, Usiello A. Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia. Nat Neurosci. 2011 Dec 18; 15(2):191-3. PMID: 22179112; PMCID: PMC3267880.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  13. Subramaniam S, Mealer RG, Sixt KM, Barrow RK, Usiello A, Snyder SH. Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9. J Biol Chem. 2010 Jul 02; 285(27):20428-32. PMID: 20424159.
    Citations: 40     Fields:    Translation:HumansAnimals
  14. Mealer R, Butler H, Hughes T. Functional fusion proteins by random transposon-based GFP insertion. Methods Cell Biol. 2008; 85:23-44. PMID: 18155457.
    Citations: 6     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.