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Wei Tao, Ph.D.

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Brigham and Women’s Hospital, Harvard Medical School, USAPostdoc02/2018Biomaterials
Tsinghua University, ChinaPh.D.06/2015Biology
Huazhong University of Science & Technology, ChinaB.S.06/2011Biomedical Engineering
2020 - 2022
Harvard & Brigham Khoury Innovation Award (PI)
Top 10 Outstanding Reviewers in 2019, Materials Horizons (IF 2019 = 14.356)
Featured Investigator at Harvard & Brigham Anaesthesia Department
2020 - 2022
Harvard & Brigham Stepping Strong Breakthrough Innovator Award (Co-PI)
2019 - 2022
Harvard & Brigham Center for Nanomedicine Research Fund (PI)
2019 - 2021
American Heart Association (AHA) Collaborative Sciences Award (Co-PI)
2019 - 2020
Harvard & Brigham Anaesthesia Department Basic Science Seed Grant (PI)
2018 - 2020
US METAvivor Early Career Investigator Award (PI)
Tsinghua-“Lin Feng” Instructor Award
Tsinghua College Academic Rookie Award
National Schcolarship for Graduate Student
13th World Pharma Congress Student Fellowship
Tsinghua First Scholarship for Research and Innovation
Tsinghua Visiting Doctoral Students Foundation Scholarship (Harvard University)
National Scholarship for Graduate Student
Huazhong University of Science and Technology Outstanding Graduate
Hong Kong Qiu Shi Science and Technologies Foundation Outstanding Student Award

Dr. Wei Tao received his B.S. in Biomedical Engineering from Huazhong University of Science & Technology (2011), and Ph.D. in Biology from Tsinghua University (2015). He held a Postdoctoral Fellowship at Harvard Medical School (HMS) and Brigham and Women’s Hospital (BWH) from 2016 to 2018. Subsequently, he was promoted to be an Instructor (Junior Faculty) at HMS in March 2018. In January 2020, his promotion to Assistant Professor gained approval from the HMS Chairs. He is an active reviewer for numerous journals. He is also a member of the Academy at Harvard Medical School. Dr. Tao currently serves as the Principal Investigator (PI) on multiple awards/grants including the U.S. METAvivor Early Career Investigator Award, Harvard Anaesthesia Department Basic Scientist Grant, Khoury Innovation Award, Center for Nanomedicine Research Fund, Stepping Strong Breakthrough Innovator Award (Co-PI), and American Heart Association (AHA) Collaborative Sciences Award (Co-PI).

Dr. Tao's primary research interest is in the design and synthesis of functional biomaterials, revealing nano-bio interactions (mechanism studies), and exploring their different biomedical applications including RNA therapeutics, cancer theranostics, wound healing, cardiovascular disease, bone regeneration, diabetes treatment and so on. His research thrusts include fundamental materials innovation as well as their various applications in translational medicine (not limited to the areas mentioned above). He is willing to have potential collaborators to expand the application fields of these materials.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Liu C, Shin J, Son S, Choe Y, Farokhzad N, Tang Z, Xiao Y, Kong N, Xie T, Kim JS, Tao W. Pnictogens in medicinal chemistry: evolution from erstwhile drugs to emerging layered photonic nanomedicine. Chem Soc Rev. 2021 Mar 01; 50(4):2260-2279. PMID: 33367452.
    Citations: 1     Fields:    
  2. Chen W, Liu C, Ji X, Joseph J, Tang Z, Ouyang J, Ouyang J, Xiao Y, Kong N, Joshi N, Farokhzad OC, Tao W, Xie T. Stanene-Based Nanosheets for ß-Elemene Delivery and Ultrasound-Mediated Combination Cancer Therapy. Angew Chem Int Ed Engl. 2021 Mar 22; 60(13):7155-7164. PMID: 33434327.
    Citations:    Fields:    
  3. Ji X, Ge L, Liu C, Tang Z, Xiao Y, Chen W, Lei Z, Gao W, Blake S, De D, Shi B, Zeng X, Kong N, Zhang X, Tao W. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics. Nat Commun. 2021 02 18; 12(1):1124. PMID: 33602928.
    Citations:    Fields:    
  4. Zhang Z, Tang Z, Farokhzad N, Chen T, Tao W. Sensitive, Rapid, Low-Cost, and Multiplexed COVID-19 Monitoring by the Wireless Telemedicine Platform. Matter. 2020 Dec 02; 3(6):1818-1820. PMID: 33289009.
  5. Yang J, Zhang X, Liu C, Wang Z, Deng L, Feng C, Tao W, Xu X, Cui W. Biologically Modified Nanoparticles as Theranostic Bionanomaterials. Progress in Materials Science. 2020; 100768. View Publication.
  6. Liu Y, Wang J, Xiong Q, Hornburg D, Tao W, Farokhzad OC. Nano-Bio Interactions in Cancer: From Therapeutics Delivery to Early Detection. Acc Chem Res. 2021 01 19; 54(2):291-301. PMID: 33180454.
    Citations: 1     Fields:    
  7. Tang Z, Zhang X, Shu Y, Guo M, Zhang H, Tao W. Insights from nanotechnology in COVID-19 treatment. Nano Today. 2021 Feb; 36:101019. PMID: 33178330.
    Citations: 4     
  8. Huang W, He L, Ouyang J, Chen Q, Liu C, Tao W, Chen T. Triangle-Shaped Tellurium Nanostars Potentiate Radiotherapy by Boosting Checkpoint Blockade Immunotherapy. Matter (Cell Press). 2020; 3(5):1725-1753. View Publication.
  9. Ouyang J, Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W. In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. Proc Natl Acad Sci U S A. 2020 11 17; 117(46):28667-28677. PMID: 33139557.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  10. Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong KW, Farokhzad OC, Tao W. A materials-science perspective on tackling COVID-19. Nat Rev Mater. 2020 Oct 14; 1-14. PMID: 33078077.
    Citations: 4     
  11. Zhou Y, Zhu F, Liu Y, Zheng M, Wang Y, Zhang D, Anraku Y, Zou Y, Li J, Wu H, Pang X, Tao W, Shimoni O, Bush AI, Xue X, Shi B. Blood-brain barrier-penetrating siRNA nanomedicine for Alzheimer's disease therapy. Sci Adv. 2020 Oct; 6(41). PMID: 33036977.
    Citations: 3     Fields:    
  12. Xiao Y, Tang Z, Wang J, Liu C, Kong N, Farokhzad OC, Tao W. Oral Insulin Delivery Platforms: Strategies To Address the Biological Barriers. Angew Chem Int Ed Engl. 2020 11 02; 59(45):19787-19795. PMID: 32705745.
    Citations: 1     Fields:    
  13. He X, Yin X, Wu J, Wickström SL, Duo Y, Du Q, Qin S, Yao S, Jing X, Hosaka K, Wu J, Jensen LD, Lundqvist A, Salter AI, Bräutigam L, Tao W, Chen Y, Kiessling R, Cao Y. Visualization of human T lymphocyte-mediated eradication of cancer cells in vivo. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22910-22919. PMID: 32859758.
    Citations:    Fields:    Translation:AnimalsCells
  14. Ouyang J, Tang Z, Farokhzad N, Kong N, Kim NY, Feng C, Blake S, Xiao Y, Liu C, Xie T, Tao W. Ultrasound Mediated Therapy: Recent Progress and Challenges in Nanoscience. Nano Today. 2020; 35:100949. View Publication.
  15. Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran AC, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. siRNA nanoparticles targeting CaMKII? in lesional macrophages improve atherosclerotic plaque stability in mice. Sci Transl Med. 2020 07 22; 12(553). PMID: 32718990.
    Citations: 1     Fields:    
  16. Feng C, Ouyang J, Tang Z, Kong N, Liu Y, Fu L, Ji X, Xie T, Farokhzad OC, Tao W. Germanene-based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection. Matter (Cell Press). 2020; 3(1):127-144. View Publication.
  17. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nat Commun. 2020 06 08; 11(1):2778. PMID: 32513979.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  18. Kong N, Ji X, Wang J, Sun X, Chen G, Fan T, Liang W, Zhang H, Xie A, Farokhzad OC, Tao W. ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications. . 2020 05 13; 20(5):3943-3955. PMID: 32243175.
    Citations: 9     
  19. Tang Z, Kong N, Ouyang J, Feng C, Kim NY, Ji X, Wang C, Farokhzad OC, Zhang H, Tao W. Phosphorus Science oriented Design and Synthesis of Multifunctional Nanomaterials for Biomedical Applications. Matter (Cell Press). 2020; 2(2):297-322. View Publication.
  20. Ji X, Kang Y, Fan T, Xiong Q, Zhang S, Tao W, Zhang H. An antimonene/Cp* Rh (phen) Cl/black phosphorus hybrid nanosheet-based Z-scheme artificial photosynthesis for enhanced photo/bio-catalytic CO2 reduction. Journal of Materials Chemistry A. 2020; 8(1):323-333. View Publication.
  21. Kong N, Tao W, Ling X, Wang J, Xiao Y, Shi S, Ji X, Shajii A, Gan ST, Kim NY, Duda DG, Xie T, Farokhzad OC, Shi J. Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition. Sci Transl Med. 2019 12 18; 11(523). PMID: 31852795.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  22. Ji X, Kang Y, Ouyang J, Chen Y, Artzi D, Zeng X, Xiao Y, Feng C, Qi B, Kim NY, Saw PE, Kong N, Farokhzad OC, Tao W. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy. Adv Sci (Weinh). 2019 Oct 02; 6(19):1901211. PMID: 31592423.
    Citations: 11     
  23. Ouyang J, Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine. Angew Chem Int Ed Engl. 2019 09 16; 58(38):13405-13410. PMID: 31365775.
    Citations: 11     Fields:    Translation:Humans
  24. Tao W, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications. Chem Soc Rev. 2019 Jun 04; 48(11):2891-2912. PMID: 31120049.
    Citations: 26     Fields:    Translation:HumansAnimals
  25. Tao W, Wang J, Parak WJ, Farokhzad OC, Shi J. Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and Its Biological Applications. ACS Nano. 2019 05 28; 13(5):4876-4882. PMID: 30985108.
    Citations: 5     Fields:    
  26. Ling X, Tu J, Wang J, Shajii A, Kong N, Feng C, Zhang Y, Yu M, Xie T, Bharwani Z, Aljaeid BM, Shi B, Tao W, Farokhzad OC. Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy. ACS Nano. 2019 01 22; 13(1):357-370. PMID: 30485068.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  27. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nat Biomed Eng. 2018 11; 2(11):850-864. PMID: 31015614.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  28. Tao W, Ji X, Zhu X, Li L, Wang J, Zhang Y, Saw PE, Li W, Kong N, Islam MA, Gan T, Zeng X, Zhang H, Mahmoudi M, Tearney GJ, Farokhzad OC. Two-Dimensional Antimonene-Based Photonic Nanomedicine for Cancer Theranostics. . 2018 Sep; 30(38):e1802061. PMID: 30043416.
    Citations: 26     Translation:Humans
  29. Rosenblum D, Joshi N, Tao W, Karp JM, Peer D. Progress and challenges towards targeted delivery of cancer therapeutics. Nat Commun. 2018 04 12; 9(1):1410. PMID: 29650952.
    Citations: 178     Fields:    Translation:Humans
  30. Zhu X, Ji X, Kong N, Chen Y, Mahmoudi M, Xu X, Ding L, Tao W, Cai T, Li Y, Gan T, Barrett A, Bharwani Z, Chen H, Farokhzad OC. Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis-Enhanced Synergistic Cancer Therapy. ACS Nano. 2018 03 27; 12(3):2922-2938. PMID: 29406760.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  31. Ding L, Zhu X, Wang Y, Shi B, Ling X, Chen H, Nan W, Barrett A, Guo Z, Tao W, Wu J, Shi X. Intracellular Fate of Nanoparticles with Polydopamine Surface Engineering and a Novel Strategy for Exocytosis-Inhibiting, Lysosome Impairment-Based Cancer Therapy. . 2017 11 08; 17(11):6790-6801. PMID: 29058908.
    Citations: 20     Translation:HumansAnimalsCells
  32. Tao W, Ji X, Xu X, Islam MA, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J, Farokhzad OC. Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy. Angew Chem Int Ed Engl. 2017 09 18; 56(39):11896-11900. PMID: 28640986.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  33. Tao W, Zhu X, Yu X, Zeng X, Xiao Q, Zhang X, Ji X, Wang X, Shi J, Zhang H, Mei L. Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics. . 2017 Jan; 29(1). PMID: 27797119.
    Citations: 76     Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.