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Wei Tao, Ph.D.

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Overview
Dr. Wei Tao is an Instructor at Harvard Medical School (HMS) and Brigham and Women’s Hospital (BWH). He received his PhD in Biology from Tsinghua University. He held a postdoctoral fellowship in Prof. Omid C. Farokhzad's group at HMS/BWH from 2016 to 2018. Subsequently, he was promoted to be an Instructor in March 2018. His research focuses on the design and synthesis of functional nanomaterials including two-dimensional (2D) materials and polymeric biomaterials, exploring their nano-bio interactions and extensive biomedical applications including RNA therapeutics, cancer theranostics, wound healing, cardiovascular disease and diabetes treatment. He has published over 60 peer-reviewed papers in Science Translational Medicine, Nature Biomedical Engineering, Nature Communications, Chemical Society Reviews, Advanced Materials, Angewandte Chemie, Advanced Science, ACS Nano, Nano Letters, etc. He is a Member of the Frontiers Editorial Board, a Founding Editor of the Topics-“Emerging Micro- and Nanotechnologies for Medical and Pharmacological Applications” and “Application of Nanobiotechnology in Pharmacology” for Frontiers in Pharmacology, and is an active reviewer for numerous prestigious journals (e.g., Nature Communications, Science Advances, Advanced Materials, ACS Nano, Nano Letters, Advanced Science, Advanced Functional Materials, Materials Horizons, Advanced Drug Delivery Reviews, Small, Biomaterials, etc.). He is also a member of the Academy at Harvard Medical School. Dr. Tao currently serves as the Principal Investigator (PI) on multiple awards/grants including the U.S. METAvivor Early Career Investigator Award, Harvard Anaesthesia Department Basic Scientist Grant, Khoury Innovation Award, Center for Nanomedicine Research Fund, and American Heart Association (AHA) Collaborative Sciences Award.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li S, Saw PE, Lin C, Nie Y, Tao W, Farokhzad OC, Zhang L, Xu X. Redox-responsive polyprodrug nanoparticles for targeted siRNA delivery and synergistic liver cancer therapy. Biomaterials. 2020 Jan 06; 234:119760. PMID: 31945619.
    Citations:    
  2. Kong N, Tao W, Ling X, Wang J, Xiao Y, Shi S, Ji X, Shajii A, Gan ST, Kim NY, Duda DG, Xie T, Farokhzad OC, Shi J. Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition. Sci Transl Med. 2019 Dec 18; 11(523). PMID: 31852795.
    Citations:    
  3. Qi B, Wang C, Ding J, Tao W. Editorial: Applications of Nanobiotechnology in Pharmacology. Front Pharmacol. 2019; 10:1451. PMID: 31866866.
    Citations:    
  4. Ji X, Kang Y, Ouyang J, Chen Y, Artzi D, Zeng X, Xiao Y, Feng C, Qi B, Kim NY, Saw PE, Kong N, Farokhzad OC, Tao W. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy. Adv Sci (Weinh). 2019 Oct 02; 6(19):1901211. PMID: 31592423.
    Citations:    
  5. Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine. Angew Chem Int Ed Engl. 2019 Sep 16; 58(38):13405-13410. PMID: 31365775.
    Citations:    
  6. Zheng M, Liu Y, Wang Y, Zhang D, Zou Y, Ruan W, Yin J, Tao W, Park JB, Shi B. ROS-Responsive Polymeric siRNA Nanomedicine Stabilized by Triple Interactions for the Robust Glioblastoma Combinational RNAi Therapy. Adv Mater. 2019 Sep; 31(37):e1903277. PMID: 31348581.
    Citations:    
  7. Tao W, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications. Chem Soc Rev. 2019 Jun 04; 48(11):2891-2912. PMID: 31120049.
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  8. Tao W, Wang J, Parak WJ, Farokhzad OC, Shi J. Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and Its Biological Applications. ACS Nano. 2019 May 28; 13(5):4876-4882. PMID: 30985108.
    Citations:    
  9. Shi S, Kong N, Feng C, Shajii A, Bejgrowicz C, Tao W, Farokhzad OC. Drug Delivery Strategies for the Treatment of Metabolic Diseases. Adv Healthc Mater. 2019 Jun; 8(12):e1801655. PMID: 30957991.
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  10. Ling X, Tu J, Wang J, Shajii A, Kong N, Feng C, Zhang Y, Yu M, Xie T, Bharwani Z, Aljaeid BM, Shi B, Tao W, Farokhzad OC. Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy. ACS Nano. 2019 01 22; 13(1):357-370. PMID: 30485068.
    Citations:    Fields:    
  11. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nat Biomed Eng. 2018 11; 2(11):850-864. PMID: 31015614.
    Citations:    
  12. Tao W, Ji X, Zhu X, Li L, Wang J, Zhang Y, Saw PE, Li W, Kong N, Islam MA, Gan T, Zeng X, Zhang H, Mahmoudi M, Tearney GJ, Farokhzad OC. Two-Dimensional Antimonene-Based Photonic Nanomedicine for Cancer Theranostics. Adv Mater. 2018 Sep; 30(38):e1802061. PMID: 30043416.
    Citations: 1     Fields:    
  13. Rosenblum D, Joshi N, Tao W, Karp JM, Peer D. Progress and challenges towards targeted delivery of cancer therapeutics. Nat Commun. 2018 04 12; 9(1):1410. PMID: 29650952.
    Citations: 11     Fields:    Translation:Humans
  14. Zhu X, Ji X, Kong N, Chen Y, Mahmoudi M, Xu X, Ding L, Tao W, Cai T, Li Y, Gan T, Barrett A, Bharwani Z, Chen H, Farokhzad OC. Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis-Enhanced Synergistic Cancer Therapy. ACS Nano. 2018 03 27; 12(3):2922-2938. PMID: 29406760.
    Citations: 7     Fields:    
  15. Ding L, Zhu X, Wang Y, Shi B, Ling X, Chen H, Nan W, Barrett A, Guo Z, Tao W, Wu J, Shi X. Intracellular Fate of Nanoparticles with Polydopamine Surface Engineering and a Novel Strategy for Exocytosis-Inhibiting, Lysosome Impairment-Based Cancer Therapy. Nano Lett. 2017 11 08; 17(11):6790-6801. PMID: 29058908.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  16. Tao W, Ji X, Xu X, Islam MA, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J, Farokhzad OC. Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy. Angew Chem Int Ed Engl. 2017 09 18; 56(39):11896-11900. PMID: 28640986.
    Citations: 14     Fields:    
  17. Tao W, Zhu X, Yu X, Zeng X, Xiao Q, Zhang X, Ji X, Wang X, Shi J, Zhang H, Mei L. Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics. Adv Mater. 2017 Jan; 29(1). PMID: 27797119.
    Citations: 27     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.