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Wei Tao, Ph.D.

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Overview
Prof. Wei Tao is the Farokhzad Family Distinguished Chair for Innovation (Endowed Chair) and Principal Investigator in the Center for Nanomedicine, Faculty Member in the Department of Anesthesiology, Perioperative, and Pain Medicine, and Faculty Member in the Gillian Reny Stepping Strong Center for Trauma Innovation at Brigham and Women’s Hospital (BWH), Harvard Medical School (HMS). He is also the first Chaired Professor as an assistant professor in his institution. He has published over 100 papers in prestigious journals including Nature/Science/Cell Press/PNAS family journals, and he is among Clarivate’s Global Highly Cited Researchers List (continuously selected every year since 2021). Prof. Tao’s research interests include biomaterials, nanotechnology and drug delivery, as well as their various applications in translational medicine.

Prof. Tao has received multiple awards/grants including the U.S. METAvivor Early Career Investigator Award, HMS/BWH Anaesthesia Department Basic Scientist Grant, Khoury Innovation Award, Center for Nanomedicine Research Fund, Stepping Strong Breakthrough Innovator Award, American Heart Association (AHA) Collaborative Sciences Award, MIT Technology Review Top Chinese Innovators Under 35 (2020 TR35), World's Top 2% Scientist (from Mendeley Data, Elsevier; continuously selected since 2019), Chemical Society Reviews Emerging Investigator Award, Advanced Materials Rising Star, Materials Today Rising Star Award, Angewandte Chemie Most Outstanding Referees Award, Materials Horizons Top 10 Outstanding Reviewers Award, Nanoscale Emerging Investigator Award, Precision Nanomedicine Rising Talents Award, etc. He also serves on numerous editorial boards including as Founding Editor-in-Chief of Biomedical Technology (Elsevier, KeAi's new journal); Associate Editor of Journal of Nanobiotechnology (Springer Nature & BMC) and Exploration (Wiley); Guest Editor of eLife, etc.; and Editorial/Advisory Board Member of Matter (Cell Press), etc.

See Prof. Tao's interview (together with Prof. Robert Langer/MIT, Prof. Samir Mitragotri/Harvard, Dr. Nicholas Warne/Pfizer, Dr. Steffen Panzner/BioNTech, etc.) in Nature Medicine (https://www.nature.com/articles/s41591-022-01826-y).

List of Research Areas:

Biomaterials, RNA Medicine, Drug Delivery, Biomedical Engineering, Nanomedicine.

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang P, Xiao Y, Sun X, Lin X, Koo S, Yaremenko AV, Qin D, Kong N, Farokhzad OC, Tao W. Cancer nanomedicine toward clinical translation: Obstacles, opportunities, and future prospects. Med (N Y). 2022 Dec 14. PMID: 36549297.
    Citations:    
  2. Huang X, Kong N, Zhang X, Cao Y, Langer R, Tao W. The landscape of mRNA nanomedicine. Nat Med. 2022 11; 28(11):2273-2287. PMID: 36357682.
    Citations: 2     Fields:    Translation:Humans
  3. Chen Y, Qin D, Zou J, Li X, Guo XD, Tang Y, Liu C, Chen W, Kong N, Zhang CY, Tao W. Living Leukocyte-Based Drug Delivery Systems. Adv Mater. 2022 Nov 01; e2207787. PMID: 36317596.
    Citations:    Fields:    
  4. Huang X, Kon E, Han X, Zhang X, Kong N, Mitchell MJ, Peer D, Tao W. Nanotechnology-based strategies against SARS-CoV-2 variants. Nat Nanotechnol. 2022 10; 17(10):1027-1037. PMID: 35982317.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  5. Ouyang J, Xie A, Zhou J, Liu R, Wang L, Liu H, Kong N, Tao W. Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging. Chem Soc Rev. 2022 Jun 20; 51(12):4996-5041. PMID: 35616098.
    Citations: 1     Fields:    Translation:Humans
  6. Xiao Y, Tang Z, Huang X, Chen W, Zhou J, Liu H, Liu C, Kong N, Tao W. Emerging mRNA technologies: delivery strategies and biomedical applications. Chem Soc Rev. 2022 May 23; 51(10):3828-3845. PMID: 35437544.
    Citations:    Fields:    Translation:HumansPHPublic Health
  7. Yi Y, Yu M, Feng C, Hao H, Zeng W, Lin C, Chen H, Lv F, Zhu D, Ji X, Mei L, Wu M, Tao W. Transforming "Cold" Tumors into "Hot" Ones via Tumor Microenvironment-Responsive siRNA Micelleplexes for Enhanced Immunotherapy. Matter (Cell Press). 2022. View Publication.
  8. Zhang Z, Zhou J, Liu C, Zhang J, Shibata Y, Kong N, Corbo C, Harris MB, Tao W. Emerging Biomimetic Nanotechnology in Orthopedic Diseases: Progress, Challenges, and Opportunities. Trends in Chemistry (Cell Press). 2022; 4(5):420-436. View Publication.
  9. Zhang D, Zhong D, Ouyang J, He J, Qi Y, Chen W, Zhang X, Tao W, Zhou M. Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy. Nat Commun. 2022 03 17; 13(1):1413. PMID: 35301299; PMCID: PMC8931093.
    Citations: 3     Fields:    Translation:Humans
  10. Kong N, Zhang R, Wu G, Sui X, Wang J, Kim NY, Blake S, De D, Xie T, Cao Y, Tao W. Intravesical delivery of KDM6A-mRNA via mucoadhesive nanoparticles inhibits the metastasis of bladder cancer. Proc Natl Acad Sci U S A. 2022 02 15; 119(7). PMID: 35131941; PMCID: PMC8851555.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  11. Huang X, Liu C, Kong N, Xiao Y, Yurdagul A, Tabas I, Tao W. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nat Protoc. 2022 03; 17(3):748-780. PMID: 35121853; PMCID: PMC9734002.
    Citations: 3     Fields:    Translation:AnimalsCells
  12. Zhao M, Mi D, Ferdows BE, Li Y, Wang R, Li J, Patel D, Kong N, Shi S, Tao W. State-of-the-art nanotechnologies for the detection, recovery, analysis and elimination of liquid biopsy components in cancer. Nano Today. 2022; 42:101361. View Publication.
  13. Chen W, Tao W. Precise Control of the Structure of Synthetic Hydrogel Networks for Precision Medicine Applications. Matter (Cell Press). 2022; 5(1):18-19. View Publication.
  14. Zhong D, Zhang D, Chen W, He J, Ren C, Zhang X, Kong N, Tao W, Zhou M. Orally deliverable strategy based on microalgal biomass for intestinal disease treatment. Sci Adv. 2021 Nov 26; 7(48):eabi9265. PMID: 34818040; PMCID: PMC8612690.
    Citations: 3     Fields:    
  15. Chen W, Schilperoort M, Cao Y, Shi J, Tabas I, Tao W. Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis. Nat Rev Cardiol. 2022 Apr; 19(4):228-249. PMID: 34759324; PMCID: PMC8580169.
    Citations: 14     Fields:    Translation:HumansCells
  16. Huang X, Wu G, Liu C, Hua X, Tang Z, Xiao Y, Chen W, Zhou J, Kong N, Huang P, Shi J, Tao W. Intercalation-Driven Formation of siRNA Nanogels for Cancer Therapy. Nano Lett. 2021 11 24; 21(22):9706-9714. PMID: 34723546.
    Citations: 2     Fields:    Translation:Humans
  17. Xiao Y, Tang Z, Huang X, Joseph J, Chen W, Liu C, Zhou J, Kong N, Joshi N, Du J, Tao W. Glucose-responsive oral insulin delivery platform for one-treatment-a-day in diabetes. Matter (Cell Press). 2021; 4(10):3269–3285. View Publication.
  18. Kong N, Zhang H, Feng C, Liu C, Xiao Y, Zhang X, Mei L, Kim JS, Tao W, Ji X. Arsenene-mediated multiple independently targeted reactive oxygen species burst for cancer therapy. Nat Commun. 2021 08 06; 12(1):4777. PMID: 34362904.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  19. Liu C, Sun S, Feng Q, Wu G, Wu Y, Kong N, Yu Z, Yao J, Zhang X, Chen W, Tang Z, Xiao Y, Huang X, Lv A, Yao C, Cheng H, Wu A, Xie T, Tao W. Arsenene Nanodots with Selective Killing Effects and their Low-Dose Combination with ß-Elemene for Cancer Therapy. Adv Mater. 2021 Sep; 33(37):e2102054. PMID: 34309925.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  20. Zhang X, Li L, Ouyang J, Zhang L, Xue J, Zhang H, Tao W. Electroactive electrospun nanofibers for tissue engineering. Nano Today. 2021; 39:101196. View Publication.
  21. Ouyang J, Feng C, Zhang X, Kong N, Tao W. Black Phosphorus in Biomedical Applications: Evolutionary Journey from Monoelemental Materials to Composite Materials. Acc Mater Res. 2021; 2(7):489–500. View Publication.
  22. Ouyang J, Zhang L, Li L, Chen W, Tang Z, Ji X, Feng C, Tao N, Kong N, Chen T, Liu YN, Tao W. Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics. Nanomicro Lett. 2021 Mar 10; 13(1):90. PMID: 34138343; PMCID: PMC8006518.
    Citations: 4     
  23. Liu C, Shin J, Son S, Choe Y, Farokhzad N, Tang Z, Xiao Y, Kong N, Xie T, Kim JS, Tao W. Pnictogens in medicinal chemistry: evolution from erstwhile drugs to emerging layered photonic nanomedicine. Chem Soc Rev. 2021 Mar 01; 50(4):2260-2279. PMID: 33367452.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  24. Ji X, Ge L, Liu C, Tang Z, Xiao Y, Chen W, Lei Z, Gao W, Blake S, De D, Shi B, Zeng X, Kong N, Zhang X, Tao W. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics. Nat Commun. 2021 02 18; 12(1):1124. PMID: 33602928; PMCID: PMC7892577.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  25. Zhang Z, Tang Z, Farokhzad N, Chen T, Tao W. Sensitive, Rapid, Low-Cost, and Multiplexed COVID-19 Monitoring by the Wireless Telemedicine Platform. Matter. 2020 Dec 02; 3(6):1818-1820. PMID: 33289009.
    Citations: 7     
  26. Tang Z, Zhang X, Shu Y, Guo M, Zhang H, Tao W. Insights from nanotechnology in COVID-19 treatment. Nano Today. 2021 Feb; 36:101019. PMID: 33178330.
    Citations: 42     
  27. Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W. In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. Proc Natl Acad Sci U S A. 2020 11 17; 117(46):28667-28677. PMID: 33139557.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  28. Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong KW, Farokhzad OC, Tao W. A materials-science perspective on tackling COVID-19. Nat Rev Mater. 2020; 5(11):847-860. PMID: 33078077; PMCID: PMC7556605.
    Citations: 43     
  29. Xiao Y, Tang Z, Wang J, Liu C, Kong N, Farokhzad OC, Tao W. Oral Insulin Delivery Platforms: Strategies To Address the Biological Barriers. Angew Chem Int Ed Engl. 2020 11 02; 59(45):19787-19795. PMID: 32705745.
    Citations: 9     Fields:    Translation:Humans
  30. Ouyang J, Tang Z, Farokhzad N, Kong N, Kim NY, Feng C, Blake S, Xiao Y, Liu C, Xie T, Tao W. Ultrasound Mediated Therapy: Recent Progress and Challenges in Nanoscience. Nano Today. 2020; 35:100949. View Publication.
  31. Feng C, Ouyang J, Tang Z, Kong N, Liu Y, Fu L, Ji X, Xie T, Farokhzad OC, Tao W. Germanene-based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection. Matter (Cell Press). 2020; 3(1):127-144. View Publication.
  32. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nat Commun. 2020 06 08; 11(1):2778. PMID: 32513979.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  33. Kong N, Ji X, Wang J, Sun X, Chen G, Fan T, Liang W, Zhang H, Xie A, Farokhzad OC, Tao W. ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications. Nano Lett. 2020 05 13; 20(5):3943-3955. PMID: 32243175.
    Citations: 28     Fields:    Translation:HumansCells
  34. Tang Z, Kong N, Ouyang J, Feng C, Kim NY, Ji X, Wang C, Farokhzad OC, Zhang H, Tao W. Phosphorus Science oriented Design and Synthesis of Multifunctional Nanomaterials for Biomedical Applications. Matter (Cell Press). 2020; 2(2):297-322. View Publication.
  35. Ji X, Kang Y, Ouyang J, Chen Y, Artzi D, Zeng X, Xiao Y, Feng C, Qi B, Kim NY, Saw PE, Kong N, Farokhzad OC, Tao W. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy. Adv Sci (Weinh). 2019 Oct 02; 6(19):1901211. PMID: 31592423; PMCID: PMC6774039.
    Citations: 25     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.