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profileJohn Samuel Brownstein, Ph.D.

TitleProfessor of Pediatrics
InstitutionBoston Children's Hospital
DepartmentPediatrics
AddressChildren's Hospital
Informatics Program/Emergency Med - 451
One Autumn Street
Boston MA 02215
Phone617/355-6998
Fax617/730-0267
vCardDownload vCard (login for email)
Other Positions
TitleProfessor of Biomedical Informatics
InstitutionHarvard Medical School
DepartmentBiomedical Informatics


Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
R01LM011965     (BROWNSTEIN, JOHN S.)May 1, 2015 - Apr 30, 2018
NIH/NLM
An Approach for Estimating Foodborne Illnesses and Assessing Risk Factors
Role: Principal Investigator
R01LM010812     (BROWNSTEIN, JOHN S.)Jul 15, 2010 - Jul 14, 2016
NIH/NLM
A Platform for Modeling the Global Impact of Climate Change on Infectious Disease
Role: Principal Investigator
G08LM009776     (BROWNSTEIN, JOHN S.)Sep 30, 2009 - Sep 29, 2013
NIH/NLM
HealthMap: Knowledge Management for Emerging Infectious Disease Intelligence
Role: Principal Investigator
R21AI073591     (BROWNSTEIN, JOHN S.)Sep 30, 2007 - Aug 31, 2010
NIH/NIAID
Empirical space-time evaluation of priority groups for influenza control
Role: Principal Investigator
R21LM009263     (BROWNSTEIN, JOHN S.)Sep 30, 2006 - Sep 29, 2009
NIH/NLM
Informatics for empirically supported influenza pandemic control strategies
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hswen Y, Brownstein JS, Liu J, Hawkins JB. Use of a Digital Health Application for Influenza Surveillance in China. Am J Public Health. 2017 Jul; 107(7):1130-1136. PMID: 28520492.
    View in: PubMed
  2. Henly S, Tuli G, Kluberg SA, Hawkins JB, Nguyen QC, Anema A, Maharana A, Brownstein JS, Nsoesie EO. Disparities in digital reporting of illness: A demographic and socioeconomic assessment. Prev Med. 2017 May 17; 101:18-22. PMID: 28528170.
    View in: PubMed
  3. Yang S, Santillana M, Brownstein JS, Gray J, Richardson S, Kou SC. Using electronic health records and Internet search information for accurate influenza forecasting. BMC Infect Dis. 2017 May 08; 17(1):332. PMID: 28482810.
    View in: PubMed
  4. Baltrusaitis K, Santillana M, Crawley AW, Chunara R, Smolinski M, Brownstein JS. Determinants of Participants' Follow-Up and Characterization of Representativeness in Flu Near You, A Participatory Disease Surveillance System. JMIR Public Health Surveill. 2017 Apr 07; 3(2):e18. PMID: 28389417.
    View in: PubMed
  5. Pierce CE, Bouri K, Pamer C, Proestel S, Rodriguez HW, Van Le H, Freifeld CC, Brownstein JS, Walderhaug M, Edwards IR, Dasgupta N. Evaluation of Facebook and Twitter Monitoring to Detect Safety Signals for Medical Products: An Analysis of Recent FDA Safety Alerts. Drug Saf. 2017 Apr; 40(4):317-331. PMID: 28044249.
    View in: PubMed
  6. Majumder MS, Nguyen CM, Cohn EL, Hswen Y, Mekaru SR, Brownstein JS. Vaccine compliance and the 2016 Arkansas mumps outbreak. Lancet Infect Dis. 2017 Apr; 17(4):361-362. PMID: 28346168.
    View in: PubMed
  7. Zinszer K, Morrison K, Verma A, Brownstein JS. Spatial Determinants of Ebola Virus Disease Risk for the West African Epidemic. PLoS Curr. 2017 Mar 31; 9. PMID: 28439448.
    View in: PubMed
  8. Harris JK, Hawkins JB, Nguyen L, Nsoesie EO, Tuli G, Mansour R, Brownstein JS. Using Twitter to Identify and Respond to Food Poisoning: The Food Safety STL Project. J Public Health Manag Pract. 2017 Feb 03. PMID: 28166175.
    View in: PubMed
  9. Ghosh S, Chakraborty P, Nsoesie EO, Cohn E, Mekaru SR, Brownstein JS, Ramakrishnan N. Temporal Topic Modeling to Assess Associations between News Trends and Infectious Disease Outbreaks. Sci Rep. 2017 Jan 19; 7:40841. PMID: 28102319.
    View in: PubMed
  10. Zinszer K, Morrison K, Brownstein JS, Marinho F, Santos AF, Nsoesie EO. Reconstruction of Zika Virus Introduction in Brazil. Emerg Infect Dis. 2017 Jan; 23(1):91-94. PMID: 27618573.
    View in: PubMed
  11. McGough SF, Brownstein JS, Hawkins JB, Santillana M. Forecasting Zika Incidence in the 2016 Latin America Outbreak Combining Traditional Disease Surveillance with Search, Social Media, and News Report Data. PLoS Negl Trop Dis. 2017 Jan; 11(1):e0005295. PMID: 28085877.
    View in: PubMed
  12. Alhamlan FS, Majumder MS, Brownstein JS, Hawkins J, Al-Abdely HM, Alzahrani A, Obaid DA, Al-Ahdal MN, BinSaeed A. Case characteristics among Middle East respiratory syndrome coronavirus outbreak and non-outbreak cases in Saudi Arabia from 2012 to 2015. BMJ Open. 2017 Jan 12; 7(1):e011865. PMID: 28082362.
    View in: PubMed
  13. Kraemer MU, Faria NR, Reiner RC, Golding N, Nikolay B, Stasse S, Johansson MA, Salje H, Faye O, Wint GR, Niedrig M, Shearer FM, Hill SC, Thompson RN, Bisanzio D, Taveira N, Nax HH, Pradelski BS, Nsoesie EO, Murphy NR, Bogoch II, Khan K, Brownstein JS, Tatem AJ, de Oliveira T, Smith DL, Sall AA, Pybus OG, Hay SI, Cauchemez S. Spread of yellow fever virus outbreak in Angola and the Democratic Republic of the Congo 2015-16: a modelling study. Lancet Infect Dis. 2017 Mar; 17(3):330-338. PMID: 28017559.
    View in: PubMed
  14. Tian H, Huang S, Zhou S, Bi P, Yang Z, Li X, Chen L, Cazelles B, Yang J, Luo L, Jing Q, Yuan W, Pei Y, Sun Z, Yue T, Wan MP, Liu Q, Wang M, Tong S, Brownstein JS, Xu B. Corrigendum to "Surface water areas significantly impacted 2014 dengue outbreaks in Guangzhou, China" [Environ. Res. 150 (2016) 299-305]. Environ Res. 2017 Apr; 154:459-460. PMID: 28012555.
    View in: PubMed
  15. Nsoesie EO, Flor L, Hawkins J, Maharana A, Skotnes T, Marinho F, Brownstein JS. Social Media as a Sentinel for Disease Surveillance: What Does Sociodemographic Status Have to Do with It? PLoS Curr. 2016 Dec 07; 8. PMID: 28123858.
    View in: PubMed
  16. Powell GA, Zinszer K, Verma A, Bahk C, Madoff L, Brownstein J, Buckeridge D. Media content about vaccines in the United States and Canada, 2012-2014: An analysis using data from the Vaccine Sentimeter. Vaccine. 2016 Dec 07; 34(50):6229-6235. PMID: 27817958.
    View in: PubMed
  17. Kluberg SA, Mekaru SR, McIver DJ, Madoff LC, Crawley AW, Smolinski MS, Brownstein JS. Global Capacity for Emerging Infectious Disease Detection, 1996-2014. Emerg Infect Dis. 2016 Oct; 22(10):E1-6. PMID: 27649306.
    View in: PubMed
  18. Johansson MA, Reich NG, Hota A, Brownstein JS, Santillana M. Evaluating the performance of infectious disease forecasts: A comparison of climate-driven and seasonal dengue forecasts for Mexico. Sci Rep. 2016 Sep 26; 6:33707. PMID: 27665707.
    View in: PubMed
  19. Majumder MS, Nguyen CM, Mekaru SR, Brownstein JS. Yellow fever vaccination coverage heterogeneities in Luanda province, Angola. Lancet Infect Dis. 2016 Sep; 16(9):993-5. PMID: 27684332.
    View in: PubMed
  20. Bogoch II, Brady OJ, Kraemer MU, German M, Creatore MI, Brent S, Watts AG, Hay SI, Kulkarni MA, Brownstein JS, Khan K. Potential for Zika virus introduction and transmission in resource-limited countries in Africa and the Asia-Pacific region: a modelling study. Lancet Infect Dis. 2016 Nov; 16(11):1237-1245. PMID: 27593584.
    View in: PubMed
  21. McGinnis DP, Brownstein JS, Patel CJ. Environment-Wide Association Study of Blood Pressure in the National Health and Nutrition Examination Survey (1999-2012). Sci Rep. 2016 Jul 26; 6:30373. PMID: 27457472; PMCID: PMC4960597.
    View in: PubMed, PubMed Central
  22. Zhou S, Tian H, Wu X, Xu B, Yang J, Chan KK, Huang S, Dong L, Brownstein J, Xu B. Genetic evidence for avian influenza H5N1 viral transmission along the Black Sea-Mediterranean Flyway. J Gen Virol. 2016 Sep; 97(9):2129-34. PMID: 27443670.
    View in: PubMed
  23. Herrera JL, Srinivasan R, Brownstein JS, Galvani AP, Meyers LA. Disease Surveillance on Complex Social Networks. PLoS Comput Biol. 2016 Jul; 12(7):e1004928. PMID: 27415615; PMCID: PMC4944951.
    View in: PubMed, PubMed Central
  24. Tian H, Huang S, Zhou S, Bi P, Yang Z, Li X, Chen L, Cazelles B, Yang J, Luo L, Jing Q, Yuan W, Pei Y, Sun Z, Yue T, Kwan MP, Liu Q, Wang M, Tong S, Brownstein JS, Xu B. Surface water areas significantly impacted 2014 dengue outbreaks in Guangzhou, China. Environ Res. 2016 Oct; 150:299-305. PMID: 27336234.
    View in: PubMed
  25. Majumder MS, Santillana M, Mekaru SR, McGinnis DP, Khan K, Brownstein JS. Utilizing Nontraditional Data Sources for Near Real-Time Estimation of Transmission Dynamics During the 2015-2016 Colombian Zika Virus Disease Outbreak. JMIR Public Health Surveill. 2016 Jun 01; 2(1):e30. PMID: 27251981; PMCID: PMC4909981.
    View in: PubMed, PubMed Central
  26. Nsoesie EO, Kraemer MU, Golding N, Pigott DM, Brady OJ, Moyes CL, Johansson MA, Gething PW, Velayudhan R, Khan K, Hay SI, Brownstein JS. Global distribution and environmental suitability for chikungunya virus, 1952 to 2015. Euro Surveill. 2016 May 19; 21(20). PMID: 27239817; PMCID: PMC4902126.
    View in: PubMed, PubMed Central
  27. Wilder-Smith A, Cohn E, Lloyd DC, Tozan Y, Brownstein JS. Internet-based media coverage on dengue in Sri Lanka between 2007 and 2015. Glob Health Action. 2016; 9:31620. PMID: 27178645; PMCID: PMC4867046.
    View in: PubMed, PubMed Central
  28. Santillana M, Nguyen AT, Louie T, Zink A, Gray J, Sung I, Brownstein JS. Cloud-based Electronic Health Records for Real-time, Region-specific Influenza Surveillance. Sci Rep. 2016 May 11; 6:25732. PMID: 27165494; PMCID: PMC4863169.
    View in: PubMed, PubMed Central
  29. Powell GE, Seifert HA, Reblin T, Burstein PJ, Blowers J, Menius JA, Painter JL, Thomas M, Pierce CE, Rodriguez HW, Brownstein JS, Freifeld CC, Bell HG, Dasgupta N. Social Media Listening for Routine Post-Marketing Safety Surveillance. Drug Saf. 2016 May; 39(5):443-54. PMID: 26798054.
    View in: PubMed
  30. Messina JP, Kraemer MU, Brady OJ, Pigott DM, Shearer FM, Weiss DJ, Golding N, Ruktanonchai CW, Gething PW, Cohn E, Brownstein JS, Khan K, Tatem AJ, Jaenisch T, Murray CJ, Marinho F, Scott TW, Hay SI. Mapping global environmental suitability for Zika virus. Elife. 2016 Apr 19; 5. PMID: 27090089; PMCID: PMC4889326.
    View in: PubMed, PubMed Central
  31. Ndeffo-Mbah ML, Durham DP, Skrip LA, Nsoesie EO, Brownstein JS, Fish D, Galvani AP. Evaluating the effectiveness of localized control strategies to curtail chikungunya. Sci Rep. 2016 Apr 05; 6:23997. PMID: 27045523; PMCID: PMC4820747.
    View in: PubMed, PubMed Central
  32. Bahk CY, Cumming M, Paushter L, Madoff LC, Thomson A, Brownstein JS. Publicly Available Online Tool Facilitates Real-Time Monitoring Of Vaccine Conversations And Sentiments. Health Aff (Millwood). 2016 Feb; 35(2):341-7. PMID: 26858390.
    View in: PubMed
  33. Bogoch II, Brady OJ, Kraemer MU, German M, Creatore MI, Kulkarni MA, Brownstein JS, Mekaru SR, Hay SI, Groot E, Watts A, Khan K. Anticipating the international spread of Zika virus from Brazil. Lancet. 2016 Jan 23; 387(10016):335-6. PMID: 26777915; PMCID: PMC4873159.
    View in: PubMed, PubMed Central
  34. Paul MJ, Sarker A, Brownstein JS, Nikfarjam A, Scotch M, Smith KL, Gonzalez G. SOCIAL MEDIA MINING FOR PUBLIC HEALTH MONITORING AND SURVEILLANCE. Pac Symp Biocomput. 2016; 21:468-79. PMID: 26776210.
    View in: PubMed
  35. Wilder-Smith A, Cohn E, Lloyd DC, Tozan Y, Brownstein JS. Internet-based media coverage on dengue in Sri Lanka between 2007 and 2015. Glob Health Action. 2016 Jan; 9(1):31620. PMID: 28157006.
    View in: PubMed
  36. Dart RC, Surratt HL, Le Lait MC, Stivers Y, Bebarta VS, Freifeld CC, Brownstein JS, Burke JJ, Kurtz SP, Dasgupta N. Diversion and Illicit Sale of Extended Release Tapentadol in the United States. Pain Med. 2016 Aug; 17(8):1490-6. PMID: 26814267; PMCID: PMC4975014.
    View in: PubMed, PubMed Central
  37. Brownstein JS, Huston JE, Steingold L, Joyce MV. On-demand delivery of influenza vaccination. Ann Intern Med. 2015 Nov 17; 163(10):806-7. PMID: 26571249.
    View in: PubMed
  38. Majumder MS, Kluberg SA, Mekaru SR, Brownstein JS. Mortality Risk Factors for Middle East Respiratory Syndrome Outbreak, South Korea, 2015. Emerg Infect Dis. 2015 Nov; 21(11):2088-90. PMID: 26488869; PMCID: PMC4622268.
    View in: PubMed, PubMed Central
  39. Santillana M, Nguyen AT, Dredze M, Paul MJ, Nsoesie EO, Brownstein JS. Combining Search, Social Media, and Traditional Data Sources to Improve Influenza Surveillance. PLoS Comput Biol. 2015 Oct; 11(10):e1004513. PMID: 26513245; PMCID: PMC4626021.
    View in: PubMed, PubMed Central
  40. Althouse BM, Scarpino SV, Meyers LA, Ayers JW, Bargsten M, Baumbach J, Brownstein JS, Castro L, Clapham H, Cummings DA, Del Valle S, Eubank S, Fairchild G, Finelli L, Generous N, George D, Harper DR, Hébert-Dufresne L, Johansson MA, Konty K, Lipsitch M, Milinovich G, Miller JD, Nsoesie EO, Olson DR, Paul M, Polgreen PM, Priedhorsky R, Read JM, Rodríguez-Barraquer I, Smith DJ, Stefansen C, Swerdlow DL, Thompson D, Vespignani A, Wesolowski A. Enhancing disease surveillance with novel data streams: challenges and opportunities. EPJ Data Sci. 2015; 4. PMID: 27990325.
    View in: PubMed
  41. Hawkins JB, Brownstein JS, Tuli G, Runels T, Broecker K, Nsoesie EO, McIver DJ, Rozenblum R, Wright A, Bourgeois FT, Greaves F. Measuring patient-perceived quality of care in US hospitals using Twitter. BMJ Qual Saf. 2016 Jun; 25(6):404-13. PMID: 26464518; PMCID: PMC4878682.
    View in: PubMed, PubMed Central
  42. McIver DJ, Grizales AM, Brownstein JS, Goldfine AB. Risk of Type 2 Diabetes Is Lower in US Adults Taking Chromium-Containing Supplements. J Nutr. 2015 Dec; 145(12):2675-82. PMID: 26446484; PMCID: PMC4656904 [Available on 12/01/16].
    View in: PubMed, PubMed Central
  43. Kesselheim AS, Campbell EG, Schneeweiss S, Rausch P, Lappin BM, Zhou EH, Seeger JD, Brownstein JS, Woloshin S, Schwartz LM, Toomey T, Dal Pan GJ, Avorn J. Erratum to: Methodological Approaches to Evaluate the Impact of FDA Drug Safety Communications. Drug Saf. 2015 Sep; 38(9):845. PMID: 26201399.
    View in: PubMed
  44. Zinszer K, Morrison K, Anema A, Majumder MS, Brownstein JS. The velocity of Ebola spread in parts of west Africa. Lancet Infect Dis. 2015 Sep; 15(9):1005-7. PMID: 26333328.
    View in: PubMed
  45. Majumder MS, Huston JE, Brownstein JS. Vaccination Compliance and the US Measles Epidemic--Reply. JAMA Pediatr. 2015 Sep; 169(9):877-8. PMID: 26348860.
    View in: PubMed
  46. Nsoesie EO, Ricketts RP, Brown HE, Fish D, Durham DP, Ndeffo Mbah ML, Christian T, Ahmed S, Marcellin C, Shelly E, Owers K, Wenzel N, Galvani AP, Brownstein JS. Spatial and Temporal Clustering of Chikungunya Virus Transmission in Dominica. PLoS Negl Trop Dis. 2015; 9(8):e0003977. PMID: 26274813; PMCID: PMC4537218.
    View in: PubMed, PubMed Central
  47. Smolinski MS, Crawley AW, Baltrusaitis K, Chunara R, Olsen JM, Wójcik O, Santillana M, Nguyen A, Brownstein JS. Flu Near You: Crowdsourced Symptom Reporting Spanning 2 Influenza Seasons. Am J Public Health. 2015 Oct; 105(10):2124-30. PMID: 26270299; PMCID: PMC4566540.
    View in: PubMed, PubMed Central
  48. Bahk CY, Goshgarian M, Donahue K, Freifeld CC, Menone CM, Pierce CE, Rodriguez H, Brownstein JS, Furberg R, Dasgupta N. Increasing Patient Engagement in Pharmacovigilance Through Online Community Outreach and Mobile Reporting Applications: An Analysis of Adverse Event Reporting for the Essure Device in the US. Pharmaceut Med. 2015; 29(6):331-340. PMID: 26635479.
    View in: PubMed
  49. Olson SH, Benedum CM, Mekaru SR, Preston ND, Mazet JA, Joly DO, Brownstein JS. Drivers of Emerging Infectious Disease Events as a Framework for Digital Detection. Emerg Infect Dis. 2015 Aug; 21(8):1285-92. PMID: 26196106; PMCID: PMC4517741.
    View in: PubMed, PubMed Central
  50. Hoen AG, Hladish TJ, Eggo RM, Lenczner M, Brownstein JS, Meyers LA. Epidemic Wave Dynamics Attributable to Urban Community Structure: A Theoretical Characterization of Disease Transmission in a Large Network. J Med Internet Res. 2015 Jul 08; 17(7):e169. PMID: 26156032; PMCID: PMC4526984.
    View in: PubMed, PubMed Central
  51. Messina JP, Pigott DM, Golding N, Duda KA, Brownstein JS, Weiss DJ, Gibson H, Robinson TP, Gilbert M, William Wint GR, Nuttall PA, Gething PW, Myers MF, George DB, Hay SI. The global distribution of Crimean-Congo hemorrhagic fever. Trans R Soc Trop Med Hyg. 2015 Aug; 109(8):503-13. PMID: 26142451; PMCID: PMC4501401.
    View in: PubMed, PubMed Central
  52. MacFadden DR, Bogoch II, Brownstein JS, Daneman N, Fisman D, German M, Khan K. A passage from India: Association between air traffic and reported cases of New Delhi Metallo-beta-lactamase 1 from 2007 to 2012. Travel Med Infect Dis. 2015 Jul-Aug; 13(4):295-9. PMID: 26143595.
    View in: PubMed
  53. Zinszer K, Kigozi R, Charland K, Dorsey G, Brewer TF, Brownstein JS, Kamya MR, Buckeridge DL. Forecasting malaria in a highly endemic country using environmental and clinical predictors. Malar J. 2015 Jun 18; 14:245. PMID: 26081838; PMCID: PMC4470343.
    View in: PubMed, PubMed Central
  54. Patel NG, Rorres C, Joly DO, Brownstein JS, Boston R, Levy MZ, Smith G. Quantitative methods of identifying the key nodes in the illegal wildlife trade network. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):7948-53. PMID: 26080413; PMCID: PMC4491747.
    View in: PubMed, PubMed Central
  55. McIver DJ, Hawkins JB, Chunara R, Chatterjee AK, Bhandari A, Fitzgerald TP, Jain SH, Brownstein JS. Characterizing Sleep Issues Using Twitter. J Med Internet Res. 2015 Jun 08; 17(6):e140. PMID: 26054530; PMCID: PMC4526927.
    View in: PubMed, PubMed Central
  56. Kesselheim AS, Campbell EG, Schneeweiss S, Rausch P, Lappin BM, Zhou EH, Seeger JD, Brownstein JS, Woloshin S, Schwartz LM, Toomey T, Dal Pan GJ, Avorn J. Methodological approaches to evaluate the impact of FDA drug safety communications. Drug Saf. 2015 Jun; 38(6):565-75. PMID: 25968811.
    View in: PubMed
  57. Goff J, Rowe A, Brownstein JS, Chunara R. Surveillance of Acute Respiratory Infections Using Community-Submitted Symptoms and Specimens for Molecular Diagnostic Testing. PLoS Curr. 2015 May 27; 7. PMID: 26075141; PMCID: PMC4455990.
    View in: PubMed, PubMed Central
  58. Ahmed SS, Oviedo-Orta E, Mekaru SR, Freifeld CC, Tougas G, Brownstein JS. Surveillance for Neisseria meningitidis Disease Activity and Transmission Using Information Technology. PLoS One. 2015; 10(5):e0127406. PMID: 25992552; PMCID: PMC4439021.
    View in: PubMed, PubMed Central
  59. Fast SM, Mekaru S, Brownstein JS, Postlethwaite TA, Markuzon N. The Role of Social Mobilization in Controlling Ebola Virus in Lofa County, Liberia. PLoS Curr. 2015 May 15; 7. PMID: 26075140; PMCID: PMC4455978.
    View in: PubMed, PubMed Central
  60. Jain SH, Powers BW, Hawkins JB, Brownstein JS. The digital phenotype. Nat Biotechnol. 2015 May; 33(5):462-3. PMID: 25965751.
    View in: PubMed
  61. Majumder MS, Cohn EL, Mekaru SR, Huston JE, Brownstein JS. Substandard vaccination compliance and the 2015 measles outbreak. JAMA Pediatr. 2015 May; 169(5):494-5. PMID: 25774618; PMCID: PMC4476536.
    View in: PubMed, PubMed Central
  62. Majumder MS, Kluberg S, Santillana M, Mekaru S, Brownstein JS. 2014 ebola outbreak: media events track changes in observed reproductive number. PLoS Curr. 2015 Apr 28; 7. PMID: 25992303; PMCID: PMC4422562.
    View in: PubMed, PubMed Central
  63. Huston JE, Mekaru SR, Kluberg S, Brownstein JS. Searching the Web for Influenza Vaccines: HealthMap Vaccine Finder. Am J Public Health. 2015 Aug; 105(8):e134-9. PMID: 25880945; PMCID: PMC4503243.
    View in: PubMed, PubMed Central
  64. Messina JP, Pigott DM, Duda KA, Brownstein JS, Myers MF, George DB, Hay SI. A global compendium of human Crimean-Congo haemorrhagic fever virus occurrence. Sci Data. 2015; 2:150016. PMID: 25977820; PMCID: PMC4409013.
    View in: PubMed, PubMed Central
  65. Chunara R, Goldstein E, Patterson-Lomba O, Brownstein JS. Estimating influenza attack rates in the United States using a participatory cohort. Sci Rep. 2015 Apr 02; 5:9540. PMID: 25835538; PMCID: PMC4894435.
    View in: PubMed, PubMed Central
  66. Bahk CY, Scales DA, Mekaru SR, Brownstein JS, Freifeld CC. Comparing timeliness, content, and disease severity of formal and informal source outbreak reporting. BMC Infect Dis. 2015 Mar 20; 15:135. PMID: 25887692; PMCID: PMC4369067.
    View in: PubMed, PubMed Central
  67. Feldstein LR, Brownstein JS, Brady OJ, Hay SI, Johansson MA. Dengue on islands: a Bayesian approach to understanding the global ecology of dengue viruses. Trans R Soc Trop Med Hyg. 2015 May; 109(5):303-12. PMID: 25771261; PMCID: PMC4401210.
    View in: PubMed, PubMed Central
  68. Nsoesie EO, Butler P, Ramakrishnan N, Mekaru SR, Brownstein JS. Monitoring disease trends using hospital traffic data from high resolution satellite imagery: a feasibility study. Sci Rep. 2015 Mar 13; 5:9112. PMID: 25765943; PMCID: PMC4357853.
    View in: PubMed, PubMed Central
  69. Nsoesie EO, Brownstein JS. Computational approaches to influenza surveillance: beyond timeliness. Cell Host Microbe. 2015 Mar 11; 17(3):275-8. PMID: 25766284; PMCID: PMC4492472.
    View in: PubMed, PubMed Central
  70. Vayena E, Salathé M, Madoff LC, Brownstein JS. Ethical challenges of big data in public health. PLoS Comput Biol. 2015 Feb; 11(2):e1003904. PMID: 25664461; PMCID: PMC4321985.
    View in: PubMed, PubMed Central
  71. Nsoesie EO, Kluberg SA, Mekaru SR, Majumder MS, Khan K, Hay SI, Brownstein JS. New digital technologies for the surveillance of infectious diseases at mass gathering events. Clin Microbiol Infect. 2015 Feb; 21(2):134-40. PMID: 25636385; PMCID: PMC4332877.
    View in: PubMed, PubMed Central
  72. Milinovich GJ, Avril SM, Clements AC, Brownstein JS, Tong S, Hu W. Using internet search queries for infectious disease surveillance: screening diseases for suitability. BMC Infect Dis. 2014 Dec 31; 14:690. PMID: 25551277; PMCID: PMC4300155.
    View in: PubMed, PubMed Central
  73. McAlarnen L, Smith K, Brownstein JS, Jerde C. Internet and free press are associated with reduced lags in global outbreak reporting. PLoS Curr. 2014 Oct 30; 6. PMID: 25642380; PMCID: PMC4234456.
    View in: PubMed, PubMed Central
  74. Bogoch II, Creatore MI, Cetron MS, Brownstein JS, Pesik N, Miniota J, Tam T, Hu W, Nicolucci A, Ahmed S, Yoon JW, Berry I, Hay SI, Anema A, Tatem AJ, MacFadden D, German M, Khan K. Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak. Lancet. 2015 Jan 03; 385(9962):29-35. PMID: 25458732; PMCID: PMC4286618.
    View in: PubMed, PubMed Central
  75. Nagar R, Yuan Q, Freifeld CC, Santillana M, Nojima A, Chunara R, Brownstein JS. A case study of the New York City 2012-2013 influenza season with daily geocoded Twitter data from temporal and spatiotemporal perspectives. J Med Internet Res. 2014 Oct 20; 16(10):e236. PMID: 25331122; PMCID: PMC4259880.
    View in: PubMed, PubMed Central
  76. Anema A, Kluberg S, Wilson K, Hogg RS, Khan K, Hay SI, Tatem AJ, Brownstein JS. Digital surveillance for enhanced detection and response to outbreaks. Lancet Infect Dis. 2014 Nov; 14(11):1035-1037. PMID: 25444397; PMCID: PMC4474182.
    View in: PubMed, PubMed Central
  77. Schwind JS, Wolking DJ, Brownstein JS, Mazet JA, Smith WA. Evaluation of local media surveillance for improved disease recognition and monitoring in global hotspot regions. PLoS One. 2014; 9(10):e110236. PMID: 25333618; PMCID: PMC4198292.
    View in: PubMed, PubMed Central
  78. Pigott DM, Golding N, Messina JP, Battle KE, Duda KA, Balard Y, Bastien P, Pratlong F, Brownstein JS, Freifeld CC, Mekaru SR, Madoff LC, George DB, Myers MF, Hay SI. Global database of leishmaniasis occurrence locations, 1960-2012. Sci Data. 2014; 1:140036. PMID: 25984344; PMCID: PMC4432653.
    View in: PubMed, PubMed Central
  79. Pigott DM, Golding N, Mylne A, Huang Z, Henry AJ, Weiss DJ, Brady OJ, Kraemer MU, Smith DL, Moyes CL, Bhatt S, Gething PW, Horby PW, Bogoch II, Brownstein JS, Mekaru SR, Tatem AJ, Khan K, Hay SI. Mapping the zoonotic niche of Ebola virus disease in Africa. Elife. 2014 Sep 08; 3:e04395. PMID: 25201877; PMCID: PMC4166725.
    View in: PubMed, PubMed Central
  80. Santillana M, Nsoesie EO, Mekaru SR, Scales D, Brownstein JS. Using clinicians' search query data to monitor influenza epidemics. Clin Infect Dis. 2014 Nov 15; 59(10):1446-50. PMID: 25115873; PMCID: PMC4296132.
    View in: PubMed, PubMed Central
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  87. Lau EH, Zheng J, Tsang TK, Liao Q, Lewis B, Brownstein JS, Sanders S, Wong JY, Mekaru SR, Rivers C, Wu P, Jiang H, Li Y, Yu J, Zhang Q, Chang Z, Liu F, Peng Z, Leung GM, Feng L, Cowling BJ, Yu H. Accuracy of epidemiological inferences based on publicly available information: retrospective comparative analysis of line lists of human cases infected with influenza A(H7N9) in China. BMC Med. 2014 May 28; 12:88. PMID: 24885692; PMCID: PMC4066833.
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  89. Scales D, Brownstein JS, Khan K, Cetron MS. Toward a county-level map of tuberculosis rates in the U.S. Am J Prev Med. 2014 May; 46(5):e49-51. PMID: 24745646; PMCID: PMC4474181.
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  93. Barboza P, Vaillant L, Le Strat Y, Hartley DM, Nelson NP, Mawudeku A, Madoff LC, Linge JP, Collier N, Brownstein JS, Astagneau P. Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks. PLoS One. 2014; 9(3):e90536. PMID: 24599062; PMCID: PMC3944226.
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  100. Ocampo AJ, Chunara R, Brownstein JS. Using search queries for malaria surveillance, Thailand. Malar J. 2013 Nov 04; 12:390. PMID: 24188069; PMCID: PMC4228243.
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  107. Leder K, Torresi J, Brownstein JS, Wilson ME, Keystone JS, Barnett E, Schwartz E, Schlagenhauf P, Wilder-Smith A, Castelli F, von Sonnenburg F, Freedman DO, Cheng AC. Travel-associated illness trends and clusters, 2000-2010. Emerg Infect Dis. 2013 Jul; 19(7):1049-73. PMID: 23763775; PMCID: PMC3713975.
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  129. Egger JR, Hoen AG, Brownstein JS, Buckeridge DL, Olson DR, Konty KJ. Usefulness of school absenteeism data for predicting influenza outbreaks, United States. Emerg Infect Dis. 2012 Aug; 18(8):1375-7. PMID: 22840354; PMCID: PMC3414019.
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  132. Turk DC, O'Connor AB, Dworkin RH, Chaudhry A, Katz NP, Adams EH, Brownstein JS, Comer SD, Dart R, Dasgupta N, Denisco RA, Klein M, Leiderman DB, Lubran R, Rappaport BA, Zacny JP, Ahdieh H, Burke LB, Cowan P, Jacobs P, Malamut R, Markman J, Michna E, Palmer P, Peirce-Sandner S, Potter JS, Raja SN, Rauschkolb C, Roland CL, Webster LR, Weiss RD, Wolf K. Research design considerations for clinical studies of abuse-deterrent opioid analgesics: IMMPACT recommendations. Pain. 2012 Oct; 153(10):1997-2008. PMID: 22770841; PMCID: PMC3617214.
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  157. Nelson NP, Brownstein JS, Hartley DM. Event-based biosurveillance of respiratory disease in Mexico, 2007-2009: connection to the 2009 influenza A(H1N1) pandemic? Euro Surveill. 2010 Jul 29; 15(30). PMID: 20684815.
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  165. Brownstein JS, Murphy SN, Goldfine AB, Grant RW, Sordo M, Gainer V, Colecchi JA, Dubey A, Nathan DM, Glaser JP, Kohane IS. Rapid identification of myocardial infarction risk associated with diabetes medications using electronic medical records. Diabetes Care. 2010 Mar; 33(3):526-31. PMID: 20009093; PMCID: PMC2827502.
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  166. Keller M, Freifeld CC, Brownstein JS. Automated vocabulary discovery for geo-parsing online epidemic intelligence. BMC Bioinformatics. 2009 Nov 24; 10:385. PMID: 19930702; PMCID: PMC2787530.
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  167. Dasgupta N, Mandl KD, Brownstein JS. Breaking the news or fueling the epidemic? Temporal association between news media report volume and opioid-related mortality. PLoS One. 2009 Nov 18; 4(11):e7758. PMID: 19924221; PMCID: PMC2771898.
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  168. Sasaki A, Hoen AG, Ozonoff A, Suzuki H, Tanabe N, Seki N, Saito R, Brownstein JS. Evidence-based tool for triggering school closures during influenza outbreaks, Japan. Emerg Infect Dis. 2009 Nov; 15(11):1841-3. PMID: 19891880; PMCID: PMC2857248.
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  169. Anema A, Freifeld CC, Druyts E, Montaner JS, Hogg RS, Brownstein JS. An assessment of global Internet-based HIV/AIDS media coverage: implications for United Nations Programme on HIV/AIDS' Global Media HIV/AIDS initiative. Int J STD AIDS. 2010 Jan; 21(1):26-9. PMID: 19833689.
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  170. Brownstein CA, Brownstein JS, Williams DS, Wicks P, Heywood JA. The power of social networking in medicine. Nat Biotechnol. 2009 Oct; 27(10):888-90. PMID: 19816437.
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  171. Brei B, Brownstein JS, George JE, Pound JM, Miller JA, Daniels TJ, Falco RC, Stafford KC, Schulze TL, Mather TN, Carroll JF, Fish D. Evaluation of the United States Department Of Agriculture Northeast Area-wide Tick Control Project by meta-analysis. Vector Borne Zoonotic Dis. 2009 Aug; 9(4):423-30. PMID: 19650737; PMCID: PMC2904192.
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  172. Brownstein JS, Freifeld CC, Madoff LC. Influenza A (H1N1) virus, 2009--online monitoring. N Engl J Med. 2009 May 21; 360(21):2156. PMID: 19423868; PMCID: PMC2922951.
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  173. Brownstein JS, Freifeld CC, Madoff LC. Digital disease detection--harnessing the Web for public health surveillance. N Engl J Med. 2009 May 21; 360(21):2153-5, 2157. PMID: 19423867; PMCID: PMC2917042.
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  174. Keller M, Blench M, Tolentino H, Freifeld CC, Mandl KD, Mawudeku A, Eysenbach G, Brownstein JS. Use of unstructured event-based reports for global infectious disease surveillance. Emerg Infect Dis. 2009 May; 15(5):689-95. PMID: 19402953; PMCID: PMC2687026.
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  175. Wilson K, Brownstein JS. Early detection of disease outbreaks using the Internet. CMAJ. 2009 Apr 14; 180(8):829-31. PMID: 19364791; PMCID: PMC2665960.
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  176. Charland KM, Buckeridge DL, Sturtevant JL, Melton F, Reis BY, Mandl KD, Brownstein JS. Effect of environmental factors on the spatio-temporal patterns of influenza spread. Epidemiol Infect. 2009 Oct; 137(10):1377-87. PMID: 19296868.
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  177. Butler SF, Budman SH, Licari A, Cassidy TA, Lioy K, Dickinson J, Brownstein JS, Benneyan JC, Green TC, Katz N. National addictions vigilance intervention and prevention program (NAVIPPRO): a real-time, product-specific, public health surveillance system for monitoring prescription drug abuse. Pharmacoepidemiol Drug Saf. 2008 Dec; 17(12):1142-54. PMID: 18932173.
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  178. Brownstein JS, Freifeld CC, Reis BY, Mandl KD. Surveillance Sans Frontières: Internet-based emerging infectious disease intelligence and the HealthMap project. PLoS Med. 2008 Jul 08; 5(7):e151. PMID: 18613747; PMCID: PMC2443186.
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  179. Brownstein JS, Mandl KD. Pediatric population size is associated with geographic patterns of acute respiratory infections among adults. Ann Emerg Med. 2008 Jul; 52(1):63-8. PMID: 18374453; PMCID: PMC2597284.
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  180. Bourgeois FT, Simons WW, Olson K, Brownstein JS, Mandl KD. Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial. J Med Internet Res. 2008 Mar 14; 10(1):e5. PMID: 18343794; PMCID: PMC2483848.
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  181. Brownstein CA, Brownstein JS. Estimating excess mortality in post-invasion Iraq. N Engl J Med. 2008 Jan 31; 358(5):445-7. PMID: 18184951.
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  182. Anema A, Mills E, Montaner J, Brownstein JS, Cooper C. Efficacy of influenza vaccination in HIV-positive patients: a systematic review and meta-analysis. HIV Med. 2008 Jan; 9(1):57-61. PMID: 18199173.
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  183. Sebastian R, Skowronski DM, Chong M, Dhaliwal J, Brownstein JS. Age-related trends in the timeliness and prediction of medical visits, hospitalizations and deaths due to pneumonia and influenza, British Columbia, Canada, 1998-2004. Vaccine. 2008 Mar 04; 26(10):1397-403. PMID: 18280620; PMCID: PMC2376828.
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  184. Freifeld CC, Mandl KD, Reis BY, Brownstein JS. HealthMap: global infectious disease monitoring through automated classification and visualization of Internet media reports. J Am Med Inform Assoc. 2008 Mar-Apr; 15(2):150-7. PMID: 18096908; PMCID: PMC2274789.
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  185. Brownstein JS, Freifeld CC. HealthMap: the development of automated real-time internet surveillance for epidemic intelligence. Euro Surveill. 2007 Nov 29; 12(11):E071129.5. PMID: 18053570.
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  186. Sturtevant JL, Anema A, Brownstein JS. The new International Health Regulations: considerations for global public health surveillance. Disaster Med Public Health Prep. 2007 Nov; 1(2):117-21. PMID: 18388639.
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  187. Brownstein JS, Sordo M, Kohane IS, Mandl KD. The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction. PLoS One. 2007 Sep 05; 2(9):e840. PMID: 17786211; PMCID: PMC1950690.
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  188. Wieland SC, Brownstein JS, Berger B, Mandl KD. Automated real time constant-specificity surveillance for disease outbreaks. BMC Med Inform Decis Mak. 2007 Jun 13; 7:15. PMID: 17567912; PMCID: PMC1919360.
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  189. Wieland SC, Brownstein JS, Berger B, Mandl KD. Density-equalizing Euclidean minimum spanning trees for the detection of all disease cluster shapes. Proc Natl Acad Sci U S A. 2007 May 29; 104(22):9404-9. PMID: 17519338; PMCID: PMC1890507.
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  190. Brownstein JS, Cassa CA, Kohane IS, Mandl KD. An unsupervised classification method for inferring original case locations from low-resolution disease maps. Int J Health Geogr. 2006 Dec 08; 5:56. PMID: 17156451; PMCID: PMC1702538.
    View in: PubMed, PubMed Central
  191. Brownstein JS, Cassa CA, Mandl KD. No place to hide--reverse identification of patients from published maps. N Engl J Med. 2006 Oct 19; 355(16):1741-2. PMID: 17050904.
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  192. Brownstein JS, Wolfe CJ, Mandl KD. Empirical evidence for the effect of airline travel on inter-regional influenza spread in the United States. PLoS Med. 2006 Sep; 3(10):e401. PMID: 16968115; PMCID: PMC1564183.
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  193. Kimia A, Brownstein JS, Olson KL, Zak V, Bourgeois FT, Mandl KD. Lumbar puncture ordering and results in the pediatric population: a promising data source for surveillance systems. Acad Emerg Med. 2006 Jul; 13(7):767-73. PMID: 16690814.
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  194. Diuk-Wasser MA, Gatewood AG, Cortinas MR, Yaremych-Hamer S, Tsao J, Kitron U, Hickling G, Brownstein JS, Walker E, Piesman J, Fish D. Spatiotemporal patterns of host-seeking Ixodes scapularis nymphs (Acari: Ixodidae) in the United States. J Med Entomol. 2006 Mar; 43(2):166-76. PMID: 16619595.
    View in: PubMed
  195. Bourgeois FT, Olson KL, Brownstein JS, McAdam AJ, Mandl KD. Validation of syndromic surveillance for respiratory infections. Ann Emerg Med. 2006 Mar; 47(3):265.e1. PMID: 16492494.
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  196. Brownstein JS, Mandl KD. Reengineering real time outbreak detection systems for influenza epidemic monitoring. AMIA Annu Symp Proc. 2006; 866. PMID: 17238486; PMCID: PMC1839573.
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  197. Brownstein JS, Skelly DK, Holford TR, Fish D. Forest fragmentation predicts local scale heterogeneity of Lyme disease risk. Oecologia. 2005 Dec; 146(3):469-75. PMID: 16187106.
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  198. Reis BY, Brownstein JS, Mandl KD. Running outside the baseline: impact of the 2004 Major League Baseball postseason on emergency department use. Ann Emerg Med. 2005 Oct; 46(4):386-7. PMID: 16183403.
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  199. Brownstein JS, Kleinman KP, Mandl KD. Identifying pediatric age groups for influenza vaccination using a real-time regional surveillance system. Am J Epidemiol. 2005 Oct 01; 162(7):686-93. PMID: 16107568; PMCID: PMC1266301.
    View in: PubMed, PubMed Central
  200. Brownstein JS, Holford TR, Fish D. Effect of Climate Change on Lyme Disease Risk in North America. Ecohealth. 2005 Mar; 2(1):38-46. PMID: 19008966.
    View in: PubMed
  201. Brownstein JS, Cassa CA, Kohane IS, Mandl KD. Reverse geocoding: concerns about patient confidentiality in the display of geospatial health data. AMIA Annu Symp Proc. 2005; 905. PMID: 16779192; PMCID: PMC1560748.
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  202. Derdáková M, Dudiòák V, Brei B, Brownstein JS, Schwartz I, Fish D. Interaction and transmission of two Borrelia burgdorferi sensu stricto strains in a tick-rodent maintenance system. Appl Environ Microbiol. 2004 Nov; 70(11):6783-8. PMID: 15528545; PMCID: PMC525125.
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  203. Madhav NK, Brownstein JS, Tsao JI, Fish D. A dispersal model for the range expansion of blacklegged tick (Acari: Ixodidae). J Med Entomol. 2004 Sep; 41(5):842-52. PMID: 15535611.
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  204. Brownstein JS, Holford TR, Fish D. Enhancing West Nile virus surveillance, United States. Emerg Infect Dis. 2004 Jun; 10(6):1129-33. PMID: 15207069; PMCID: PMC3323153.
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  205. Brownstein JS, Hett E, O'Neill SL. The potential of virulent Wolbachia to modulate disease transmission by insects. J Invertebr Pathol. 2003 Sep; 84(1):24-9. PMID: 13678709.
    View in: PubMed
  206. Brownstein JS, Holford TR, Fish D. A climate-based model predicts the spatial distribution of the Lyme disease vector Ixodes scapularis in the United States. Environ Health Perspect. 2003 Jul; 111(9):1152-7. PMID: 12842766; PMCID: PMC1241567.
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  207. Brownstein JS, Rosen H, Purdy D, Miller JR, Merlino M, Mostashari F, Fish D. Spatial analysis of West Nile virus: rapid risk assessment of an introduced vector-borne zoonosis. Vector Borne Zoonotic Dis. 2002; 2(3):157-64. PMID: 12737545.
    View in: PubMed
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