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Maxim Gerashchenko, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gerashchenko MV, Peterfi Z, Yim SH, Gladyshev VN. Translation elongation rate varies among organs and decreases with age. Nucleic Acids Res. 2021 01 25; 49(2):e9. PMID: 33264395.
    Citations:    Fields:    Translation:AnimalsCells
  2. Gerashchenko MV. Choice of Ribonucleases for Ribosome Profiling Experiments. Methods Mol Biol. 2021; 2252:239-248. PMID: 33765279.
    Citations:    Fields:    
  3. Gerashchenko MV, Gladyshev VN. Measuring Organ-Specific Translation Elongation Rate in Mice. Methods Mol Biol. 2021; 2252:189-200. PMID: 33765276.
    Citations:    Fields:    
  4. Santesmasses D, Castro JP, Zenin AA, Shindyapina AV, Gerashchenko MV, Zhang B, Kerepesi C, Yim SH, Fedichev PO, Gladyshev VN. COVID-19 is an emergent disease of aging. Aging Cell. 2020 10; 19(10):e13230. PMID: 33006233.
    Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
  5. Gerashchenko MV, Nesterchuk MV, Smekalova EM, Paulo JA, Kowalski PS, Akulich KA, Bogorad R, Dmitriev SE, Gygi S, Zatsepin T, Anderson DG, Gladyshev VN, Koteliansky VE. Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes. Sci Rep. 2020 09 23; 10(1):15473. PMID: 32968084.
    Citations: 2     Fields:    Translation:AnimalsCells
  6. Anisimova AS, Meerson MB, Gerashchenko MV, Kulakovskiy IV, Dmitriev SE, Gladyshev VN. Multifaceted deregulation of gene expression and protein synthesis with age. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):15581-15590. PMID: 32576685.
    Citations: 4     Fields:    Translation:AnimalsCells
  7. Liberman N, O'Brown ZK, Earl AS, Boulias K, Gerashchenko MV, Wang SY, Fritsche C, Fady PE, Dong A, Gladyshev VN, Greer EL. N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance. Sci Adv. 2020 Apr; 6(17):eaaz4370. PMID: 32494643.
    Citations: 5     Fields:    
  8. Kaya A, Mariotti M, Tyshkovskiy A, Zhou X, Hulke ML, Ma S, Gerashchenko MV, Koren A, Gladyshev VN. Molecular signatures of aneuploidy-driven adaptive evolution. Nat Commun. 2020 01 30; 11(1):588. PMID: 32001709.
    Citations:    Fields:    Translation:AnimalsCells
  9. Smekalova EM, Gerashchenko MV, O'Connor PBF, Whittaker CA, Kauffman KJ, Fefilova AS, Zatsepin TS, Bogorad RL, Baranov PV, Langer R, Gladyshev VN, Anderson DG, Koteliansky V. In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation. Mol Ther Nucleic Acids. 2020 Mar 06; 19:252-266. PMID: 31855834.
    Citations: 4     
  10. Tyshkovskiy A, Bozaykut P, Borodinova AA, Gerashchenko MV, Ables GP, Garratt M, Khaitovich P, Clish CB, Miller RA, Gladyshev VN. Identification and Application of Gene Expression Signatures Associated with Lifespan Extension. Cell Metab. 2019 09 03; 30(3):573-593.e8. PMID: 31353263.
    Citations: 17     Fields:    Translation:AnimalsCells
  11. O'Connell AE, Gerashchenko MV, O'Donohue MF, Rosen SM, Huntzinger E, Gleeson D, Galli A, Ryder E, Cao S, Murphy Q, Kazerounian S, Morton SU, Schmitz-Abe K, Gladyshev VN, Gleizes PE, Séraphin B, Agrawal PB. Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation. PLoS Genet. 2019 02; 15(2):e1007917. PMID: 30707697.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  12. Lobanov AV, Heaphy SM, Turanov AA, Gerashchenko MV, Pucciarelli S, Devaraj RR, Xie F, Petyuk VA, Smith RD, Klobutcher LA, Atkins JF, Miceli C, Hatfield DL, Baranov PV, Gladyshev VN. Position-dependent termination and widespread obligatory frameshifting in Euplotes translation. Nat Struct Mol Biol. 2017 01; 24(1):61-68. PMID: 27870834.
    Citations: 20     Fields:    Translation:AnimalsCells
  13. Gao J, Barroso C, Zhang P, Kim HM, Li S, Labrador L, Lightfoot J, Gerashchenko MV, Labunskyy VM, Dong MQ, Martinez-Perez E, Colaiácovo MP. N-terminal acetylation promotes synaptonemal complex assembly in C. elegans. Genes Dev. 2016 11 01; 30(21):2404-2416. PMID: 27881602.
    Citations: 7     Fields:    Translation:AnimalsCells
  14. Gerashchenko MV, Gladyshev VN. Ribonuclease selection for ribosome profiling. Nucleic Acids Res. 2017 01 25; 45(2):e6. PMID: 27638886.
    Citations: 36     Fields:    Translation:AnimalsCells
  15. Kaya A, Gerashchenko MV, Seim I, Labarre J, Toledano MB, Gladyshev VN. Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins. Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):10685-90. PMID: 26261310.
    Citations: 22     Fields:    Translation:AnimalsCells
  16. Seim I, Ma S, Zhou X, Gerashchenko MV, Lee SG, Suydam R, George JC, Bickham JW, Gladyshev VN. The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal. Aging (Albany NY). 2014 Oct; 6(10):879-99. PMID: 25411232.
    Citations: 18     Fields:    Translation:AnimalsCells
  17. Kaya A, Lobanov AV, Gerashchenko MV, Koren A, Fomenko DE, Koc A, Gladyshev VN. Thiol peroxidase deficiency leads to increased mutational load and decreased fitness in Saccharomyces cerevisiae. Genetics. 2014 Nov; 198(3):905-17. PMID: 25173844.
    Citations: 8     Fields:    Translation:AnimalsCells
  18. Fang X, Seim I, Huang Z, Gerashchenko MV, Xiong Z, Turanov AA, Zhu Y, Lobanov AV, Fan D, Yim SH, Yao X, Ma S, Yang L, Lee SG, Kim EB, Bronson RT, Šumbera R, Buffenstein R, Zhou X, Krogh A, Park TJ, Zhang G, Wang J, Gladyshev VN. Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes. Cell Rep. 2014 Sep 11; 8(5):1354-64. PMID: 25176646.
    Citations: 45     Fields:    Translation:AnimalsCells
  19. Gerashchenko MV, Gladyshev VN. Translation inhibitors cause abnormalities in ribosome profiling experiments. Nucleic Acids Res. 2014; 42(17):e134. PMID: 25056308.
    Citations: 106     Fields:    Translation:AnimalsCells
  20. Lee BC, Kaya A, Ma S, Kim G, Gerashchenko MV, Yim SH, Hu Z, Harshman LG, Gladyshev VN. Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status. Nat Commun. 2014 Apr 07; 5:3592. PMID: 24710037.
    Citations: 77     Fields:    Translation:AnimalsCells
  21. Labunskyy VM, Gerashchenko MV, Delaney JR, Kaya A, Kennedy BK, Kaeberlein M, Gladyshev VN. Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. PLoS Genet. 2014 Jan; 10(1):e1004019. PMID: 24391512.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  22. Seim I, Fang X, Xiong Z, Lobanov AV, Huang Z, Ma S, Feng Y, Turanov AA, Zhu Y, Lenz TL, Gerashchenko MV, Fan D, Hee Yim S, Yao X, Jordan D, Xiong Y, Ma Y, Lyapunov AN, Chen G, Kulakova OI, Sun Y, Lee SG, Bronson RT, Moskalev AA, Sunyaev SR, Zhang G, Krogh A, Wang J, Gladyshev VN. Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii. Nat Commun. 2013; 4:2212. PMID: 23962925.
    Citations: 84     Fields:    Translation:AnimalsCells
  23. Gerashchenko MV, Lobanov AV, Gladyshev VN. Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17394-9. PMID: 23045643.
    Citations: 118     Fields:    Translation:AnimalsCells
  24. Shumilina E, Soldà A, Gerashchenko M, Gladyshev VN, Dikiy A. ¹H, ¹³C, and ¹5N NMR resonance assignments of reduced full length and shortened forms of the Grx domain of Mus musculus TGR. Biomol NMR Assign. 2012 Apr; 6(1):103-7. PMID: 21901408.
    Citations: 1     Fields:    Translation:AnimalsCells
  25. Gerashchenko MV, Su D, Gladyshev VN. CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes. J Biol Chem. 2010 Feb 12; 285(7):4595-602. PMID: 20018845.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  26. Gerashchenko MV, Chernoivanenko IS, Moldaver MV, Minin AA. Dynein is a motor for nuclear rotation while vimentin IFs is a "brake". Cell Biol Int. 2009 Oct; 33(10):1057-64. PMID: 19560548.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.