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Aimee Louise McNamara, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ramos-Méndez J, LaVerne JA, Domínguez-Kondo N, Milligan J, Štepán V, Stefanová K, Perrot Y, Villagrasa C, Shin WG, Incerti S, McNamara A, Paganetti H, Perl J, Schuemann J, Faddegon B. TOPAS-nBio validation for simulating water radiolysis and DNA damage under low-LET irradiation. Phys Med Biol. 2021 09 03; 66(17). PMID: 34412044; PMCID: PMC8639218.
    Citations: 1     Fields:    Translation:Cells
  2. Marteinsdottir M, Wang CC, McNamara AL, Depauw N, Shin J, Paganetti H. The impact of variable RBE in proton therapy for left-sided breast cancer when estimating normal tissue complications in the heart and lung. Phys Med Biol. 2020 Dec 09. PMID: 33296885.
    Citations: 3     Fields:    
  3. Stainforth R, Schuemann J, McNamara AL, Wilkins RC, Chauhan V. Challenges in the quantification approach to a radiation relevant adverse outcome pathway for lung cancer. Int J Radiat Biol. 2021; 97(1):85-101. PMID: 32909875.
    Citations:    Fields:    Translation:HumansCells
  4. Sung W, Grassberger C, McNamara AL, Basler L, Ehrbar S, Tanadini-Lang S, Hong TS, Paganetti H. A tumor-immune interaction model for hepatocellular carcinoma based on measured lymphocyte counts in patients undergoing radiotherapy. Radiother Oncol. 2020 10; 151:73-81. PMID: 32679308.
    Citations: 11     Fields:    Translation:HumansCells
  5. Zhu H, McNamara AL, McMahon SJ, Ramos-Mendez J, Henthorn NT, Faddegon B, Held KD, Perl J, Li J, Paganetti H, Schuemann J. Cellular Response to Proton Irradiation: A Simulation Study with TOPAS-nBio. Radiat Res. 2020 07 08; 194(1):9-21. PMID: 32401689; PMCID: PMC7484135.
    Citations: 6     Fields:    Translation:HumansCells
  6. Zhu H, McNamara AL, Ramos-Mendez J, McMahon SJ, Henthorn NT, Faddegon B, Held KD, Perl J, Li J, Paganetti H, Schuemann J. A parameter sensitivity study for simulating DNA damage after proton irradiation using TOPAS-nBio. Phys Med Biol. 2020 04 23; 65(8):085015. PMID: 32101803.
    Citations: 10     Fields:    Translation:Cells
  7. Wang CC, McNamara AL, Shin J, Schuemann J, Grassberger C, Taghian AG, Jimenez RB, MacDonald SM, Paganetti H. End-of-Range Radiobiological Effect on Rib Fractures in Patients Receiving Proton Therapy for Breast Cancer. Int J Radiat Oncol Biol Phys. 2020 07 01; 107(3):449-454. PMID: 32240774.
    Citations: 11     Fields:    Translation:Humans
  8. McNamara AL, Hall DC, Shusharina N, Liu A, Wei X, Ajdari A, Mohan R, Liao Z, Paganetti H. Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial. Radiother Oncol. 2020 06; 147:8-14. PMID: 32224318.
    Citations: 4     Fields:    Translation:Humans
  9. McNamara A, Willers H, Paganetti H. Modelling variable proton relative biological effectiveness for treatment planning. Br J Radiol. 2020 Mar; 93(1107):20190334. PMID: 31738081; PMCID: PMC7066955.
    Citations: 12     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  10. Rudek B, McNamara A, Ramos-Méndez J, Byrne H, Kuncic Z, Schuemann J. Radio-enhancement by gold nanoparticles and their impact on water radiolysis for x-ray, proton and carbon-ion beams. Phys Med Biol. 2019 08 28; 64(17):175005. PMID: 31295730.
    Citations: 8     Fields:    
  11. Zhu H, Chen Y, Sung W, McNamara AL, Tran LT, Burigo LN, Rosenfeld AB, Li J, Faddegon B, Schuemann J, Paganetti H. The microdosimetric extension in TOPAS: development and comparison with published data. Phys Med Biol. 2019 07 11; 64(14):145004. PMID: 31117056.
    Citations: 4     Fields:    Translation:Humans
  12. Byrne H, McNamara A, Kuncic Z. IMPACT OF NANOPARTICLE CLUSTERING ON DOSE RADIO-ENHANCEMENT. Radiat Prot Dosimetry. 2019 May 01; 183(1-2):50-54. PMID: 30535388.
    Citations: 2     Fields:    Translation:Cells
  13. Schuemann J, McNamara AL, Ramos-Méndez J, Perl J, Held KD, Paganetti H, Incerti S, Faddegon B. TOPAS-nBio: An Extension to the TOPAS Simulation Toolkit for Cellular and Sub-cellular Radiobiology. Radiat Res. 2019 02; 191(2):125-138. PMID: 30609382; PMCID: PMC6377808.
    Citations: 34     Fields:    Translation:HumansCells
  14. Schuemann J, McNamara AL, Warmenhoven JW, Henthorn NT, Kirkby KJ, Merchant MJ, Ingram S, Paganetti H, Held KD, Ramos-Mendez J, Faddegon B, Perl J, Goodhead DT, Plante I, Rabus H, Nettelbeck H, Friedland W, Kundrát P, Ottolenghi A, Baiocco G, Barbieri S, Dingfelder M, Incerti S, Villagrasa C, Bueno M, Bernal MA, Guatelli S, Sakata D, Brown JMC, Francis Z, Kyriakou I, Lampe N, Ballarini F, Carante MP, Davídková M, Štepán V, Jia X, Cucinotta FA, Schulte R, Stewart RD, Carlson DJ, Galer S, Kuncic Z, Lacombe S, Milligan J, Cho SH, Sawakuchi G, Inaniwa T, Sato T, Li W, Solov'yov AV, Surdutovich E, Durante M, Prise KM, McMahon SJ. A New Standard DNA Damage (SDD) Data Format. Radiat Res. 2019 01; 191(1):76-92. PMID: 30407901; PMCID: PMC6407706.
    Citations: 21     Fields:    Translation:Cells
  15. McNamara AL, Ramos-Méndez J, Perl J, Held K, Dominguez N, Moreno E, Henthorn NT, Kirkby KJ, Meylan S, Villagrasa C, Incerti S, Faddegon B, Paganetti H, Schuemann J. Geometrical structures for radiation biology research as implemented in the TOPAS-nBio toolkit. Phys Med Biol. 2018 09 06; 63(17):175018. PMID: 30088810.
    Citations: 17     Fields:    Translation:Humans
  16. Ramos-Méndez J, Perl J, Schuemann J, McNamara A, Paganetti H, Faddegon B. Monte Carlo simulation of chemistry following radiolysis with TOPAS-nBio. Phys Med Biol. 2018 05 17; 63(10):105014. PMID: 29697057.
    Citations: 20     Fields:    Translation:HumansCells
  17. Blake SJ, Cheng Z, McNamara A, Lu M, Vial P, Kuncic Z. A high DQE water-equivalent EPID employing an array of plastic-scintillating fibers for simultaneous imaging and dosimetry in radiotherapy. Med Phys. 2018 May; 45(5):2154-2168. PMID: 29577337.
    Citations: 2     Fields:    
  18. Tran LT, Chartier L, Bolst D, Pogossov A, Guatelli S, Petasecca M, Lerch MLF, Prokopovich DA, Reinhard MI, Clasie B, Depauw N, Kooy H, Flanz JB, McNamara A, Paganetti H, Beltran C, Furutani K, Perevertaylo VL, Jackson M, Rosenfeld AB. Characterization of proton pencil beam scanning and passive beam using a high spatial resolution solid-state microdosimeter. Med Phys. 2017 Nov; 44(11):6085-6095. PMID: 28887837.
    Citations: 5     Fields:    
  19. McMahon SJ, McNamara AL, Schuemann J, Paganetti H, Prise KM. A general mechanistic model enables predictions of the biological effectiveness of different qualities of radiation. Sci Rep. 2017 09 07; 7(1):10790. PMID: 28883414.
    Citations: 18     Fields:    Translation:HumansCells
  20. Sung W, Ye SJ, McNamara AL, McMahon SJ, Hainfeld J, Shin J, Smilowitz HM, Paganetti H, Schuemann J. Correction: Dependence of gold nanoparticle radiosensitization on cell geometry. Nanoscale. 2017 08 10; 9(31):11338. PMID: 28758663.
    Citations: 1     Fields:    
  21. Sung W, Ye SJ, McNamara AL, McMahon SJ, Hainfeld J, Shin J, Smilowitz HM, Paganetti H, Schuemann J. Dependence of gold nanoparticle radiosensitization on cell geometry. Nanoscale. 2017 May 11; 9(18):5843-5853. PMID: 28429022.
    Citations: 22     Fields:    
  22. Underwood TS, Sung W, McFadden CH, McMahon SJ, Hall DC, McNamara AL, Paganetti H, Sawakuchi GO, Schuemann J. Comparing stochastic proton interactions simulated using TOPAS-nBio to experimental data from fluorescent nuclear track detectors. Phys Med Biol. 2017 04 21; 62(8):3237-3249. PMID: 28350546.
    Citations: 3     Fields:    Translation:Cells
  23. McNamara A, Geng C, Turner R, Mendez JR, Perl J, Held K, Faddegon B, Paganetti H, Schuemann J. Validation of the radiobiology toolkit TOPAS-nBio in simple DNA geometries. Phys Med. 2017 Jan; 33:207-215. PMID: 28017738.
    Citations: 25     Fields:    Translation:Cells
  24. McNamara AL, Kam WW, Scales N, McMahon SJ, Bennett JW, Byrne HL, Schuemann J, Paganetti H, Banati R, Kuncic Z. Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol. Phys Med Biol. 2016 08 21; 61(16):5993-6010. PMID: 27435339.
    Citations: 15     Fields:    Translation:HumansCells
  25. Toghyani M, Gillam JE, McNamara AL, Kuncic Z. Polarisation-based coincidence event discrimination: an in silico study towards a feasible scheme for Compton-PET. Phys Med Biol. 2016 08 07; 61(15):5803-17. PMID: 27405797.
    Citations: 1     Fields:    
  26. McNamara AL, Schuemann J, Paganetti H. A phenomenological relative biological effectiveness (RBE) model for proton therapy based on all published in vitro cell survival data. Phys Med Biol. 2015 Nov 07; 60(21):8399-416. PMID: 26459756.
    Citations: 70     Fields:    Translation:HumansCells
  27. Polster L, Schuemann J, Rinaldi I, Burigo L, McNamara AL, Stewart RD, Attili A, Carlson DJ, Sato T, Ramos Méndez J, Faddegon B, Perl J, Paganetti H. Extension of TOPAS for the simulation of proton radiation effects considering molecular and cellular endpoints. Phys Med Biol. 2015 Jul 07; 60(13):5053-70. PMID: 26061666.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  28. Deshpande S, McNamara AL, Holloway L, Metcalfe P, Vial P. Feasibility study of a dual detector configuration concept for simultaneous megavoltage imaging and dose verification in radiotherapy. Med Phys. 2015 Apr; 42(4):1753-64. PMID: 25832065.
    Citations: 2     Fields:    Translation:Humans
  29. Byrne HL, Domanova W, McNamara AL, Incerti S, Kuncic Z. The cytoplasm as a radiation target: an in silico study of microbeam cell irradiation. Phys Med Biol. 2015 Mar 21; 60(6):2325-37. PMID: 25715947.
    Citations: 5     Fields:    Translation:Cells
  30. McNamara AL, Toghyani M, Gillam JE, Wu K, Kuncic Z. Towards optimal imaging with PET: an in silico feasibility study. Phys Med Biol. 2014 Dec 21; 59(24):7587-600. PMID: 25415271.
    Citations: 1     Fields:    
  31. Blake SJ, McNamara AL, Vial P, Holloway L, Kuncic Z. Optimisation of the imaging and dosimetric characteristics of an electronic portal imaging device employing plastic scintillating fibres using Monte Carlo simulations. Phys Med Biol. 2014 Nov 21; 59(22):6827-40. PMID: 25332310.
    Citations: 1     Fields:    Translation:Humans
  32. Blake SJ, McNamara AL, Deshpande S, Holloway L, Greer PB, Kuncic Z, Vial P. Characterization of a novel EPID designed for simultaneous imaging and dose verification in radiotherapy. Med Phys. 2013 Sep; 40(9):091902. PMID: 24007153.
    Citations: 3     Fields:    Translation:Humans
  33. Blake SJ, Vial P, Holloway L, Greer PB, McNamara AL, Kuncic Z. Characterization of optical transport effects on EPID dosimetry using Geant4. Med Phys. 2013 Apr; 40(4):041708. PMID: 23556878.
    Citations: 10     Fields:    
  34. Kam WW, McNamara AL, Lake V, Banos C, Davies JB, Kuncic Z, Banati RB. Predicted ionisation in mitochondria and observed acute changes in the mitochondrial transcriptome after gamma irradiation: a Monte Carlo simulation and quantitative PCR study. Mitochondrion. 2013 Nov; 13(6):736-42. PMID: 23485772.
    Citations: 6     Fields:    Translation:HumansCells
  35. Byrne HL, McNamara AL, Domanova W, Guatelli S, Kuncic Z. Radiation damage on sub-cellular scales: beyond DNA. Phys Med Biol. 2013 Mar 07; 58(5):1251-67. PMID: 23380838.
    Citations: 3     Fields:    Translation:CellsPHPublic Health
  36. Kuncic Z, Byrne HL, McNamara AL, Guatelli S, Domanova W, Incerti S. In silico nanodosimetry: new insights into nontargeted biological responses to radiation. Comput Math Methods Med. 2012; 2012:147252. PMID: 22701142.
    Citations: 5     Fields:    Translation:HumansCells
  37. Blake S, Vial P, Holloway L, McNamara A, Greer P, Kuncic Z. SU-E-I-109: Sensitivity Analysis of an Electronic Portal Imaging Device Monte Carlo Model to Variations in Optical Transport Parameters. Med Phys. 2012 Jun; 39(6Part5):3650. PMID: 28517636.
    Citations:    Fields:    
  38. McNamara AL, Guatelli S, Prokopovich DA, Reinhard MI, Rosenfeld AB. A comparison of X-ray and proton beam low energy secondary electron track structures using the low energy models of Geant4. Int J Radiat Biol. 2012 Jan; 88(1-2):164-70. PMID: 22040102.
    Citations: 3     Fields:    
  39. McNamara AL, Heijnis H, Fierro D, Reinhard MI. The determination of the efficiency of a Compton suppressed HPGe detector using Monte Carlo simulations. J Environ Radioact. 2012 Apr; 106:1-7. PMID: 22304994.
    Citations:    Fields:    Translation:PHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.