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Yuwen Zhou, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K25HL148837 (ZHOU, IRIS YUWEN) Sep 25, 2020 - Aug 31, 2024
    Quantitative MRI-PET Imaging of Pulmonary Fibrosis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhou IY, Ramsay IA, Ay I, Pantazopoulos P, Rotile NJ, Wong A, Caravan P, Gale EM. Positron Emission Tomography-Magnetic Resonance Imaging Pharmacokinetics, In Vivo Biodistribution, and Whole-Body Elimination of Mn-PyC3A. Invest Radiol. 2021 04 01; 56(4):261-270. PMID: 33136686; PMCID: PMC7933117.
    Citations:    Fields:    Translation:Animals
  2. Le Fur M, Zhou IY, Catalano O, Caravan P. Toward Molecular Imaging of Intestinal Pathology. Inflamm Bowel Dis. 2020 09 18; 26(10):1470-1484. PMID: 32793946.
    Citations: 2     Fields:    Translation:Humans
  3. Zhou IY, Tanabe KK, Fuchs BC, Caravan P. Collagen-targeted molecular imaging in diffuse liver diseases. Abdom Radiol (NY). 2020 11; 45(11):3545-3556. PMID: 32737546.
    Citations: 1     Fields:    Translation:Animals
  4. Zhou IY, Catalano OA, Caravan P. Advances in functional and molecular MRI technologies in chronic liver diseases. J Hepatol. 2020 11; 73(5):1241-1254. PMID: 32585160; PMCID: PMC7572718.
    Citations: 6     Fields:    Translation:Humans
  5. Zhou IY, Clavijo Jordan V, Rotile NJ, Akam E, Krishnan S, Arora G, Krishnan H, Slattery H, Warner N, Mercaldo N, Farrar CT, Wellen J, Martinez R, Schlerman F, Tanabe KK, Fuchs BC, Caravan P. Advanced MRI of Liver Fibrosis and Treatment Response in a Rat Model of Nonalcoholic Steatohepatitis. Radiology. 2020 07; 296(1):67-75. PMID: 32343209; PMCID: PMC7325703.
    Citations: 6     Fields:    Translation:Animals
  6. Akam EA, Abston E, Rotile NJ, Slattery HR, Zhou IY, Lanuti M, Caravan P. Improving the reactivity of hydrazine-bearing MRI probes for in vivo imaging of lung fibrogenesis. Chem Sci. 2020 Jan 07; 11(1):224-231. PMID: 32728411.
    Citations: 10     
  7. Luo J, Abaci Turk E, Gagoski B, Copeland N, Zhou IY, Young V, Bibbo C, Robinson JN, Zera C, Barth WH, Roberts DJ, Sun PZ, Grant PE. Preliminary evaluation of dynamic glucose enhanced MRI of the human placenta during glucose tolerance test. Quant Imaging Med Surg. 2019 Oct; 9(10):1619-1627. PMID: 31728306; PMCID: PMC6828580.
    Citations: 2     
  8. Ji Y, Paulsen J, Zhou IY, Lu D, Machado P, Qiu B, Song YQ, Sun PZ. In vivo microscopic diffusional kurtosis imaging with symmetrized double diffusion encoding EPI. Magn Reson Med. 2019 01; 81(1):533-541. PMID: 30260504.
    Citations: 4     Fields:    Translation:Animals
  9. Zhou IY, Lu D, Ji Y, Wu L, Wang E, Cheung JS, Zhang XA, Sun PZ. Determination of multipool contributions to endogenous amide proton transfer effects in global ischemia with high spectral resolution in vivo chemical exchange saturation transfer MRI. Magn Reson Med. 2019 01; 81(1):645-652. PMID: 30058148.
    Citations: 15     Fields:    Translation:HumansAnimals
  10. Lu D, Jiang Y, Ji Y, Zhou IY, Mandeville E, Lo EH, Wang X, Sun PZ. JOURNAL CLUB: Evaluation of Diffusion Kurtosis Imaging of Stroke Lesion With Hemodynamic and Metabolic MRI in a Rodent Model of Acute Stroke. AJR Am J Roentgenol. 2018 Apr; 210(4):720-727. PMID: 29470156; PMCID: PMC6814247.
    Citations: 7     Fields:    Translation:Animals
  11. Wang E, Wu Y, Cheung JS, Zhou IY, Igarashi T, Zhang X, Sun PZ. pH imaging reveals worsened tissue acidification in diffusion kurtosis lesion than the kurtosis/diffusion lesion mismatch in an animal model of acute stroke. J Cereb Blood Flow Metab. 2017 Oct; 37(10):3325-3333. PMID: 28752790.
    Citations: 12     Fields:    Translation:AnimalsCells
  12. Wu Y, Zhou IY, Lu D, Manderville E, Lo EH, Zheng H, Sun PZ. pH-sensitive amide proton transfer effect dominates the magnetization transfer asymmetry contrast during acute ischemia-quantification of multipool contribution to in vivo CEST MRI. Magn Reson Med. 2018 03; 79(3):1602-1608. PMID: 28733991.
    Citations: 13     Fields:    Translation:Animals
  13. Wu Y, Zhou IY, Igarashi T, Longo DL, Aime S, Sun PZ. A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol. Magn Reson Med. 2018 03; 79(3):1553-1558. PMID: 28686805.
    Citations: 18     Fields:    Translation:Animals
  14. Cao P, Hyder F, Zhou IY, Zhang JW, Xie VB, Tsang A, Wu EX. Simultaneous spin-echo and gradient-echo BOLD measurements by dynamic MRS. NMR Biomed. 2017 Sep; 30(9). PMID: 28574615.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  15. Zhou IY, Wang E, Cheung JS, Zhang X, Fulci G, Sun PZ. Quantitative chemical exchange saturation transfer (CEST) MRI of glioma using Image Downsampling Expedited Adaptive Least-squares (IDEAL) fitting. Sci Rep. 2017 03 07; 7(1):84. PMID: 28273886.
    Citations: 27     Fields:    Translation:AnimalsCells
  16. Chan KC, Zhou IY, Liu SS, van der Merwe Y, Fan SJ, Hung VK, Chung SK, Wu WT, So KF, Wu EX. Longitudinal Assessments of Normal and Perilesional Tissues in Focal Brain Ischemia and Partial Optic Nerve Injury with Manganese-enhanced MRI. Sci Rep. 2017 02 23; 7:43124. PMID: 28230106.
    Citations: 10     Fields:    Translation:Animals
  17. Zhou IY, Fuss TL, Igarashi T, Jiang W, Zhou X, Cheng LL, Sun PZ. Tissue Characterization with Quantitative High-Resolution Magic Angle Spinning Chemical Exchange Saturation Transfer Z-Spectroscopy. Anal Chem. 2016 11 01; 88(21):10379-10383. PMID: 27709896; PMCID: PMC5441684.
    Citations: 4     Fields:    Translation:Animals
  18. Zhou IY, Guo Y, Igarashi T, Wang Y, Mandeville E, Chan ST, Wen L, Vangel M, Lo EH, Ji X, Sun PZ. Fast diffusion kurtosis imaging (DKI) with Inherent COrrelation-based Normalization (ICON) enhances automatic segmentation of heterogeneous diffusion MRI lesion in acute stroke. NMR Biomed. 2016 12; 29(12):1670-1677. PMID: 27696558.
    Citations: 6     Fields:    Translation:Animals
  19. Liu X, Zhou F, Li X, Qian W, Cui J, Zhou IY, Luk KD, Wu EX, Hu Y. Organization of the intrinsic functional network in the cervical spinal cord: A resting state functional MRI study. Neuroscience. 2016 Nov 12; 336:30-38. PMID: 27590264.
    Citations: 14     Fields:    Translation:Humans
  20. Guo Y, Zhou IY, Chan ST, Wang Y, Mandeville ET, Igarashi T, Lo EH, Ji X, Sun PZ. pH-sensitive MRI demarcates graded tissue acidification during acute stroke - pH specificity enhancement with magnetization transfer and relaxation-normalized amide proton transfer (APT) MRI. Neuroimage. 2016 Nov 01; 141:242-249. PMID: 27444569.
    Citations: 32     Fields:    Translation:Animals
  21. Jiang W, Zhou IY, Wen L, Zhou X, Sun PZ. A theoretical analysis of chemical exchange saturation transfer echo planar imaging (CEST-EPI) steady state solution and the CEST sensitivity efficiency-based optimization approach. Contrast Media Mol Imaging. 2016 09; 11(5):415-423. PMID: 27312932.
    Citations: 10     Fields:    
  22. Wu Y, Kim J, Chan ST, Zhou IY, Guo Y, Igarashi T, Zheng H, Guo G, Sun PZ. Comparison of image sensitivity between conventional tensor-based and fast diffusion kurtosis imaging protocols in a rodent model of acute ischemic stroke. NMR Biomed. 2016 May; 29(5):625-30. PMID: 26918411.
    Citations: 11     Fields:    Translation:Animals
  23. Sun PZ, Xiao G, Zhou IY, Guo Y, Wu R. A method for accurate pH mapping with chemical exchange saturation transfer (CEST) MRI. Contrast Media Mol Imaging. 2016 05; 11(3):195-202. PMID: 26689424.
    Citations: 14     Fields:    
  24. Chan RW, Ho LC, Zhou IY, Gao PP, Chan KC, Wu EX. Structural and Functional Brain Remodeling during Pregnancy with Diffusion Tensor MRI and Resting-State Functional MRI. PLoS One. 2015; 10(12):e0144328. PMID: 26658306.
    Citations: 9     Fields:    Translation:Animals
  25. Wu R, Xiao G, Zhou IY, Ran C, Sun PZ. Quantitative chemical exchange saturation transfer (qCEST) MRI - omega plot analysis of RF-spillover-corrected inverse CEST ratio asymmetry for simultaneous determination of labile proton ratio and exchange rate. NMR Biomed. 2015 Mar; 28(3):376-83. PMID: 25615718.
    Citations: 21     Fields:    
  26. Cheng JS, Gao PP, Zhou IY, Chan RW, Chan Q, Mak HK, Khong PL, Wu EX. Resting-state fMRI using passband balanced steady-state free precession. PLoS One. 2014; 9(3):e91075. PMID: 24622278.
    Citations: 1     Fields:    Translation:HumansAnimals
  27. Gao PP, Zhang JW, Cheng JS, Zhou IY, Wu EX. The inferior colliculus is involved in deviant sound detection as revealed by BOLD fMRI. Neuroimage. 2014 May 01; 91:220-7. PMID: 24486979.
    Citations: 10     Fields:    Translation:Animals
  28. Chan KC, Fan SJ, Chan RW, Cheng JS, Zhou IY, Wu EX. In vivo visuotopic brain mapping with manganese-enhanced MRI and resting-state functional connectivity MRI. Neuroimage. 2014 Apr 15; 90:235-45. PMID: 24394694.
    Citations: 21     Fields:    Translation:Animals
  29. Zhou IY, Gao DS, Chow AM, Fan S, Cheung MM, Ling C, Liu X, Cao P, Guo H, Man K, Wu EX. Effect of diffusion time on liver DWI: an experimental study of normal and fibrotic livers. Magn Reson Med. 2014 Nov; 72(5):1389-96. PMID: 24258877.
    Citations: 6     Fields:    Translation:Animals
  30. Zhou IY, Chan RW, Ho LC, Wu EX. Longitudinal metabolic changes in the hippocampus and thalamus of the maternal brain revealed by proton magnetic resonance spectroscopy. Neurosci Lett. 2013 Oct 11; 553:170-5. PMID: 23994391.
    Citations: 3     Fields:    Translation:Animals
  31. Zhou IY, Liang YX, Chan RW, Gao PP, Cheng JS, Hu Y, So KF, Wu EX. Brain resting-state functional MRI connectivity: morphological foundation and plasticity. Neuroimage. 2014 Jan 01; 84:1-10. PMID: 23988270.
    Citations: 23     Fields:    Translation:Animals
  32. Lau C, Zhang JW, Cheng JS, Zhou IY, Cheung MM, Wu EX. Noninvasive fMRI investigation of interaural level difference processing in the rat auditory subcortex. PLoS One. 2013; 8(8):e70706. PMID: 23940631.
    Citations: 4     Fields:    Translation:Animals
  33. Ding AY, Li Q, Zhou IY, Ma SJ, Tong G, McAlonan GM, Wu EX. MR diffusion tensor imaging detects rapid microstructural changes in amygdala and hippocampus following fear conditioning in mice. PLoS One. 2013; 8(1):e51704. PMID: 23382811.
    Citations: 15     Fields:    Translation:HumansAnimals
  34. Zhou IY, Ding AY, Li Q, McAlonan GM, Wu EX. Magnetic resonance spectroscopy reveals N-acetylaspartate reduction in hippocampus and cingulate cortex after fear conditioning. Psychiatry Res. 2012 Nov 30; 204(2-3):178-83. PMID: 23137804.
    Citations: 11     Fields:    Translation:Animals
  35. Zhang JW, Lau C, Cheng JS, Xing KK, Zhou IY, Cheung MM, Wu EX. Functional magnetic resonance imaging of sound pressure level encoding in the rat central auditory system. Neuroimage. 2013 Jan 15; 65:119-26. PMID: 23041525.
    Citations: 6     Fields:    Translation:Animals
  36. Cheung MM, Lau C, Zhou IY, Chan KC, Zhang JW, Fan SJ, Wu EX. High fidelity tonotopic mapping using swept source functional magnetic resonance imaging. Neuroimage. 2012 Jul 16; 61(4):978-86. PMID: 22445952.
    Citations: 9     Fields:    Translation:Animals
  37. Cheung MM, Lau C, Zhou IY, Chan KC, Cheng JS, Zhang JW, Ho LC, Wu EX. BOLD fMRI investigation of the rat auditory pathway and tonotopic organization. Neuroimage. 2012 Apr 02; 60(2):1205-11. PMID: 22297205.
    Citations: 23     Fields:    Translation:Animals
  38. Chan KC, Fan SJ, Zhou IY, Wu EX. In vivo chromium-enhanced MRI of the retina. Magn Reson Med. 2012 Oct; 68(4):1202-10. PMID: 22213133.
    Citations: 13     Fields:    Translation:Animals
  39. Zhou IY, Cheung MM, Lau C, Chan KC, Wu EX. Balanced steady-state free precession fMRI with intravascular susceptibility contrast agent. Magn Reson Med. 2012 Jul; 68(1):65-73. PMID: 22127794.
    Citations: 9     Fields:    Translation:Animals
  40. Chan KC, Cheng JS, Fan S, Zhou IY, Yang J, Wu EX. In vivo evaluation of retinal and callosal projections in early postnatal development and plasticity using manganese-enhanced MRI and diffusion tensor imaging. Neuroimage. 2012 Feb 01; 59(3):2274-83. PMID: 21985904.
    Citations: 29     Fields:    Translation:AnimalsCells
  41. Lau C, Zhang JW, Xing KK, Zhou IY, Cheung MM, Chan KC, Wu EX. BOLD responses in the superior colliculus and lateral geniculate nucleus of the rat viewing an apparent motion stimulus. Neuroimage. 2011 Oct 01; 58(3):878-84. PMID: 21741483.
    Citations: 11     Fields:    Translation:Animals
  42. Cheung JS, Au WY, Ha SY, Kim D, Jensen JH, Zhou IY, Cheung MM, Wu Y, Guo H, Khong PL, Brown TR, Brittenham GM, Wu EX. Reduced transverse relaxation rate (RR2) for improved sensitivity in monitoring myocardial iron in thalassemia. J Magn Reson Imaging. 2011 Jun; 33(6):1510-6. PMID: 21591022.
    Citations: 4     Fields:    Translation:HumansCells
  43. Lau C, Zhou IY, Cheung MM, Chan KC, Wu EX. BOLD temporal dynamics of rat superior colliculus and lateral geniculate nucleus following short duration visual stimulation. PLoS One. 2011 Apr 29; 6(4):e18914. PMID: 21559482.
    Citations: 17     Fields:    Translation:AnimalsCells
  44. Chan KC, Cheng JS, Fan S, Zhou IY, Wu EX. In vivo manganese-enhanced MRI and diffusion tensor imaging of developing and impaired visual brains. Annu Int Conf IEEE Eng Med Biol Soc. 2011; 2011:7005-8. PMID: 22255951.
    Citations: 4     Fields:    Translation:AnimalsCells
  45. Chow AM, Zhou IY, Fan SJ, Chan KW, Chan KC, Wu EX. Metabolic changes in visual cortex of neonatal monocular enucleated rat: a proton magnetic resonance spectroscopy study. Int J Dev Neurosci. 2011 Feb; 29(1):25-30. PMID: 20950681.
    Citations: 10     Fields:    Translation:Animals
  46. Chan KC, Li J, Kau P, Zhou IY, Cheung MM, Lau C, Yang J, So KF, Wu EX. In vivo retinotopic mapping of superior colliculus using manganese-enhanced magnetic resonance imaging. Neuroimage. 2011 Jan 01; 54(1):389-95. PMID: 20633657.
    Citations: 33     Fields:    Translation:AnimalsCells
  47. Chan KC, Cheung MM, Xing KK, Zhou IY, Chow AM, Lau C, So KF, Wu EX. In vivo MRI study of the visual system in normal, developing and injured rodent brains. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:5689-92. PMID: 21097319.
    Citations: 1     Fields:    Translation:Animals
  48. Chan KC, Xing KK, Cheung MM, Zhou IY, Wu EX. Functional MRI of postnatal visual development in normal and hypoxic-ischemic-injured superior colliculi. Neuroimage. 2010 Feb 01; 49(3):2013-20. PMID: 19879366.
    Citations: 17     Fields:    Translation:Animals
  49. Chan KC, Xing K, Cheung MM, Zhou IY, Wu EX. Functional MRI of postnatal visual development in normal rat superior colliculi. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:4436-9. PMID: 19963832.
    Citations: 1     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.