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Chad M Walesky, Ph.D.

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  1. F32DK111151 (WALESKY, CHAD MICHAEL) Sep 7, 2016 - Sep 6, 2019
    NIH/NIDDK
    A Balancing Act: Role of HNF4?/?-catenin in Hepatobiliary Development and Cholangiocarcinoma Formation
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. McGreal SR, Bhushan B, Walesky C, McGill MR, Lebofsky M, Kandel SE, Winefield RD, Jaeschke H, Zachara NE, Zhang Z, Tan EP, Slawson C, Apte U. Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis. Toxicol Sci. 2018 04 01; 162(2):599-610. PMID: 29325178.
    Citations:    Fields:    
  2. Walesky C, Goessling W. WNTing no RASt for hepatocellular carcinoma. Hepatology. 2017 05; 65(5):1435-1437. PMID: 28295459.
    Citations:    Fields:    Translation:Humans
  3. Abou-Alfa GK, Andersen JB, Chapman W, Choti M, Forbes SJ, Gores GJ, Hong TS, Harding JJ, Vander Heiden MG, Javle M, Kelley RK, Kwong LN, Lowery M, Merrell A, Miyabe K, Rhim A, Saha S, Sia D, Tanasanvimon S, Venook A, Valle JW, Walesky C, Whetstine J, Willenbring H, Zhu AX, Mayer D, Stanger BZ. Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference. J Gastrointest Oncol. 2016 Dec; 7(6):819-827. PMID: 28078106.
    Citations: 2     
  4. Walesky C, Goessling W. Nature and nurture: Environmental toxins and biliary atresia. Hepatology. 2016 09; 64(3):717-9. PMID: 27349921.
    Citations:    Fields:    Translation:Humans
  5. Sun L, Beggs K, Borude P, Edwards G, Bhushan B, Walesky C, Roy N, Manley MW, Gunewardena S, O'Neil M, Li H, Apte U. Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling. Am J Physiol Gastrointest Liver Physiol. 2016 07 01; 311(1):G91-G104. PMID: 27151938.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N. Corrigendum: Mutant IDH inhibits HNF-4a to block hepatocyte differentiation and promote biliary cancer. Nature. 2015 Dec 03; 528(7580):152. PMID: 26580013.
    Citations:    Fields:    
  7. Gunewardena S, Walesky C, Apte U. Global Gene Expression Changes in Liver Following Hepatocyte Nuclear Factor 4 alpha deletion in Adult Mice. Genom Data. 2015 Sep 01; 5:126-128. PMID: 26120557.
    Citations: 2     
  8. Walesky C, Apte U. Role of hepatocyte nuclear factor 4a (HNF4a) in cell proliferation and cancer. Gene Expr. 2015; 16(3):101-8. PMID: 25700366.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  9. Bhushan B, Walesky C, Manley M, Gallagher T, Borude P, Edwards G, Monga SP, Apte U. Pro-regenerative signaling after acetaminophen-induced acute liver injury in mice identified using a novel incremental dose model. Am J Pathol. 2014 Nov; 184(11):3013-25. PMID: 25193591.
    Citations: 20     Fields:    Translation:AnimalsCells
  10. Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N. Mutant IDH inhibits HNF-4a to block hepatocyte differentiation and promote biliary cancer. Nature. 2014 Sep 04; 513(7516):110-4. PMID: 25043045.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  11. Bhushan B, Borude P, Edwards G, Walesky C, Cleveland J, Li F, Ma X, Apte U. Role of bile acids in liver injury and regeneration following acetaminophen overdose. Am J Pathol. 2013 Nov; 183(5):1518-1526. PMID: 24007882.
    Citations: 20     Fields:    Translation:Animals
  12. Walesky C, Edwards G, Borude P, Gunewardena S, O'Neil M, Yoo B, Apte U. Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents. Hepatology. 2013 Jun; 57(6):2480-90. PMID: 23315968.
    Citations: 34     Fields:    Translation:AnimalsCells
  13. Borude P, Edwards G, Walesky C, Li F, Ma X, Kong B, Guo GL, Apte U. Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice. Hepatology. 2012 Dec; 56(6):2344-52. PMID: 22730081.
    Citations: 25     Fields:    Translation:AnimalsCells
  14. Walesky C, Gunewardena S, Terwilliger EF, Edwards G, Borude P, Apte U. Hepatocyte-specific deletion of hepatocyte nuclear factor-4a in adult mice results in increased hepatocyte proliferation. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 01; 304(1):G26-37. PMID: 23104559.
    Citations: 26     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.