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Jeroen Egide Geert Eyckmans, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang K, Cloonan PE, Sundaram S, Liu F, Das SL, Ewoldt JK, Bays JL, Tomp S, Toepfer CN, Marsiglia JDC, Gorham J, Reichart D, Eyckmans J, Seidman JG, Seidman CE, Chen CS. Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization. Sci Adv. 2021 Oct 15; 7(42):eabh3995. PMID: 34652945.
    Citations:    Fields:    
  2. Das SL, Bose P, Lejeune E, Reich DH, Chen C, Eyckmans J. Extracellular Matrix Alignment Directs Provisional Matrix Assembly and Three Dimensional Fibrous Tissue Closure. Tissue Eng Part A. 2021 May 12. PMID: 33979548.
    Citations:    Fields:    
  3. Zhou DW, Fernández-Yagüe MA, Holland EN, García AF, Castro NS, O'Neill EB, Eyckmans J, Chen CS, Fu J, Schlaepfer DD, García AJ. Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair. Nat Commun. 2021 04 21; 12(1):2359. PMID: 33883558.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Tefft JB, Chen CS, Eyckmans J. Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure. APL Bioeng. 2021 Mar; 5(1):016102. PMID: 33511324.
    Citations: 1     
  5. Song HG, Lammers A, Sundaram S, Rubio L, Chen AX, Li L, Eyckmans J, Bhatia SN, Chen CS. Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues. Adv Funct Mater. 2020 Nov 25; 30(48). PMID: 33613149.
    Citations: 2     
  6. Nguyen DT, Lee E, Alimperti S, Norgard RJ, Wong A, Lee JJ, Eyckmans J, Stanger BZ, Chen CS. A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling. Sci Adv. 2019 08; 5(8):eaav6789. PMID: 31489365.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  7. Mailand E, Li B, Eyckmans J, Bouklas N, Sakar MS. Surface and Bulk Stresses Drive Morphological Changes in Fibrous Microtissues. Biophys J. 2019 09 03; 117(5):975-986. PMID: 31427068.
    Citations:    Fields:    Translation:AnimalsCells
  8. Yoon C, Choi C, Stapleton S, Mirabella T, Howes C, Dong L, King J, Yang J, Oberai A, Eyckmans J, Chen CS. Myosin IIA-mediated forces regulate multicellular integrity during vascular sprouting. Mol Biol Cell. 2019 07 22; 30(16):1974-1984. PMID: 31318321.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  9. Seeherman HJ, Berasi SP, Brown CT, Martinez RX, Juo ZS, Jelinsky S, Cain MJ, Grode J, Tumelty KE, Bohner M, Grinberg O, Orr N, Shoseyov O, Eyckmans J, Chen C, Morales PR, Wilson CG, Vanderploeg EJ, Wozney JM. A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix. Sci Transl Med. 2019 04 24; 11(489). PMID: 31019025.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  10. Cheng D, Jayne RK, Tamborini A, Eyckmans J, White AE, Chen CS. Studies of 3D directed cell migration enabled by direct laser writing of curved wave topography. Biofabrication. 2019 02 25; 11(2):021001. PMID: 30721899.
    Citations: 4     Fields:    Translation:HumansCells
  11. Bose P, Eyckmans J, Nguyen TD, Chen CS, Reich DH. Effects of Geometry on the Mechanics and Alignment of Three-Dimensional Engineered Microtissues. ACS Biomater Sci Eng. 2019 Aug 12; 5(8):3843-3855. PMID: 33438424.
    Citations: 2     
  12. Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS. Force Generation via ß-Cardiac Myosin, Titin, and a-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Dev Cell. 2018 01 08; 44(1):87-96.e5. PMID: 29316444.
    Citations: 43     Fields:    Translation:HumansCells
  13. Bose P, Huang CY, Eyckmans J, Chen CS, Reich DH. Fabrication and Mechanical Properties Measurements of 3D Microtissues for the Study of Cell-Matrix Interactions. Methods Mol Biol. 2018; 1722:303-328. PMID: 29264812.
    Citations:    Fields:    Translation:AnimalsCells
  14. Li L, Eyckmans J, Chen CS. Designer biomaterials for mechanobiology. Nat Mater. 2017 11 24; 16(12):1164-1168. PMID: 29170549.
    Citations: 30     Fields:    Translation:HumansAnimals
  15. Polacheck WJ, Kutys ML, Yang J, Eyckmans J, Wu Y, Vasavada H, Hirschi KK, Chen CS. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017 12 14; 552(7684):258-262. PMID: 29160307.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  16. Eyckmans J, Chen CS. Making bone via nanoscale kicks. Nat Biomed Eng. 2017 Sep; 1(9):689-690. PMID: 31015669.
    Citations: 1     Fields:    
  17. Alimperti S, Mirabella T, Bajaj V, Polacheck W, Pirone DM, Duffield J, Eyckmans J, Assoian RK, Chen CS. Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):8758-8763. PMID: 28765370.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  18. Eyckmans J, Chen CS. 3D culture models of tissues under tension. J Cell Sci. 2017 01 01; 130(1):63-70. PMID: 27909243.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  19. Sakar MS, Eyckmans J, Pieters R, Eberli D, Nelson BJ, Chen CS. Cellular forces and matrix assembly coordinate fibrous tissue repair. Nat Commun. 2016 Mar 16; 7:11036. PMID: 26980715.
    Citations: 34     Fields:    Translation:AnimalsCells
  20. Chaturvedi RR, Stevens KR, Solorzano RD, Schwartz RE, Eyckmans J, Baranski JD, Stapleton SC, Bhatia SN, Chen CS. Patterning vascular networks in vivo for tissue engineering applications. Tissue Eng Part C Methods. 2015 May; 21(5):509-17. PMID: 25390971.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  21. Eyckmans J, Chen CS. Stem cell differentiation: sticky mechanical memory. Nat Mater. 2014 Jun; 13(6):542-3. PMID: 24845990.
    Citations: 5     Fields:    Translation:HumansCells
  22. Baranski JD, Chaturvedi RR, Stevens KR, Eyckmans J, Carvalho B, Solorzano RD, Yang MT, Miller JS, Bhatia SN, Chen CS. Geometric control of vascular networks to enhance engineered tissue integration and function. Proc Natl Acad Sci U S A. 2013 May 07; 110(19):7586-91. PMID: 23610423.
    Citations: 71     Fields:    Translation:HumansAnimalsCells
  23. Eyckmans J, Roberts SJ, Bolander J, Schrooten J, Chen CS, Luyten FP. Mapping calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors. Biomaterials. 2013 Jun; 34(19):4612-21. PMID: 23537666.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  24. Eyckmans J, Lin GL, Chen CS. Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells. Biol Open. 2012 Nov 15; 1(11):1058-68. PMID: 23213385.
    Citations: 20     
  25. Wang YK, Yu X, Cohen DM, Wozniak MA, Yang MT, Gao L, Eyckmans J, Chen CS. Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension. Stem Cells Dev. 2012 May 01; 21(7):1176-86. PMID: 21967638.
    Citations: 90     Fields:    Translation:HumansCells
  26. Eyckmans J, Boudou T, Yu X, Chen CS. A hitchhiker's guide to mechanobiology. Dev Cell. 2011 Jul 19; 21(1):35-47. PMID: 21763607.
    Citations: 152     Fields:    Translation:HumansAnimalsCells
  27. Crabbe A, Vandeputte C, Dresselaers T, Sacido AA, Verdugo JM, Eyckmans J, Luyten FP, Van Laere K, Verfaillie CM, Himmelreich U. Effects of MRI contrast agents on the stem cell phenotype. Cell Transplant. 2010; 19(8):919-36. PMID: 20350351.
    Citations: 38     Fields:    Translation:AnimalsCells
  28. Maréchal M, Eyckmans J, Schrooten J, Schepers E, Luyten FP, van Steenberghe D. Bone augmentation with autologous periosteal cells and two different calcium phosphate scaffolds under an occlusive titanium barrier: an experimental study in rabbits. J Periodontol. 2008 May; 79(5):896-904. PMID: 18454669.
    Citations: 2     Fields:    Translation:AnimalsCells
  29. Eyckmans J, Luyten FP. Species specificity of ectopic bone formation using periosteum-derived mesenchymal progenitor cells. Tissue Eng. 2006 Aug; 12(8):2203-13. PMID: 16968161.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  30. De Bari C, Dell'Accio F, Vanlauwe J, Eyckmans J, Khan IM, Archer CW, Jones EA, McGonagle D, Mitsiadis TA, Pitzalis C, Luyten FP. Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis. Arthritis Rheum. 2006 Apr; 54(4):1209-21. PMID: 16575900.
    Citations: 113     Fields:    Translation:HumansCells
  31. Van Damme A, Thorrez L, Ma L, Vandenburgh H, Eyckmans J, Dell'Accio F, De Bari C, Luyten F, Lillicrap D, Collen D, VandenDriessche T, Chuah MK. Efficient lentiviral transduction and improved engraftment of human bone marrow mesenchymal cells. Stem Cells. 2006 Apr; 24(4):896-907. PMID: 16339997.
    Citations: 31     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.