Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jeffrey Theodore Borenstein, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21HL106585 (BORENSTEIN, JEFFREY T.) Dec 1, 2010 - Nov 30, 2013
    Biomimetic Design and Construction of an Artificial Lung
    Role: Principal Investigator
  2. R21GM103435 (BORENSTEIN, JEFFREY T.) Aug 1, 2010 - Sep 30, 2013
    A High-Throughput Flow System to Probe Biomechanics of Pathophysiology
    Role: Principal Investigator
  3. R21RR031253 (BORENSTEIN, JEFFREY T) Aug 1, 2010 - Apr 30, 2013
    A High-Throughput Flow System to Probe Biomechanics of Pathophysiology
    Role: Principal Investigator
  4. R01DC006848 (BORENSTEIN, JEFFREY T.) Apr 1, 2004 - Oct 31, 2016
    Micromechanical Device for Intracochlear Drug Delivery
    Role: Principal Investigator
  5. R56DC006848 (BORENSTEIN, JEFFREY T) Apr 1, 2004 - Jul 31, 2010
    Micromechanical Device for Intracochlear Drug Delivery
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Schueler J, Borenstein J, Buti L, Dong M, Masmoudi F, Hribar K, Anderson E, Sommergruber W. How to build a tumor: An industry perspective. Drug Discov Today. 2022 Oct; 27(10):103329. PMID: 35908685; PMCID: PMC9585375.
    Citations: 1     Fields:    Translation:Humans
  2. Astor TL, Borenstein JT. The microfluidic artificial lung: Mimicking nature's blood path design to solve the biocompatibility paradox. Artif Organs. 2022 Jul; 46(7):1227-1239. PMID: 35514275.
    Citations:    Fields:    Translation:Humans
  3. Vedula EM, Isenberg BC, Santos J, Lai W, Lewis DJ, Sutherland D, Roberts TR, Harea GT, Wells C, Teece B, Urban J, Risoleo T, Solt D, Leazer S, Chung K, Sukavaneshvar S, Batchinsky AI, Borenstein JT. Multilayer Scaling of a Biomimetic Microfluidic Oxygenator. ASAIO J. 2022 10 01; 68(10):1312-1319. PMID: 36194101; PMCID: PMC9521578.
    Citations:    Fields:    Translation:Animals
  4. Santos JA, Gimbel AA, Peppas A, Truslow JG, Lang DA, Sukavaneshvar S, Solt D, Mulhern TJ, Markoski A, Kim ES, Hsiao JC, Lewis DJ, Harjes DI, DiBiasio C, Charest JL, Borenstein JT. Design and construction of three-dimensional physiologically-based vascular branching networks for respiratory assist devices. Lab Chip. 2021 11 25; 21(23):4637-4651. PMID: 34730597.
    Citations: 1     Fields:    Translation:Animals
  5. Santos J, Vedula EM, Lai W, Isenberg BC, Lewis DJ, Lang D, Sutherland D, Roberts TR, Harea GT, Wells C, Teece B, Karandikar P, Urban J, Risoleo T, Gimbel A, Solt D, Leazer S, Chung KK, Sukavaneshvar S, Batchinsky AI, Borenstein JT. Toward Development of a Higher Flow Rate Hemocompatible Biomimetic Microfluidic Blood Oxygenator. Micromachines (Basel). 2021 Jul 28; 12(8). PMID: 34442512.
    Citations: 1     
  6. Gard AL, Luu RJ, Miller CR, Maloney R, Cain BP, Marr EE, Burns DM, Gaibler R, Mulhern TJ, Wong CA, Alladina J, Coppeta JR, Liu P, Wang JP, Azizgolshani H, Fezzie RF, Balestrini JL, Isenberg BC, Medoff BD, Finberg RW, Borenstein JT. High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro. Sci Rep. 2021 07 22; 11(1):14961. PMID: 34294757.
    Citations: 4     Fields:    Translation:HumansCells
  7. Rogers MT, Gard AL, Gaibler R, Mulhern TJ, Strelnikov R, Azizgolshani H, Cain BP, Isenberg BC, Haroutunian NJ, Raustad NE, Keegan PM, Lech MP, Tomlinson L, Borenstein JT, Charest JL, Williams C. A high-throughput microfluidic bilayer co-culture platform to study endothelial-pericyte interactions. Sci Rep. 2021 06 09; 11(1):12225. PMID: 34108507.
    Citations: 1     Fields:    Translation:HumansCells
  8. Markoski A, Wong IY, Borenstein JT. 3D Printed Monolithic Device for the Microfluidic Capture, Perfusion, and Analysis of Multicellular Spheroids. Front Med Technol. 2021; 3:646441. PMID: 35047914; PMCID: PMC8757790.
  9. Gimbel AA, Hsiao JC, Kim ES, Lewis DJ, Risoleo TF, Urban JN, Borenstein JT. A high gas transfer efficiency microfluidic oxygenator for extracorporeal respiratory assist applications in critical care medicine. Artif Organs. 2021 Aug; 45(8):E247-E264. PMID: 33561881.
    Citations: 2     Fields:    Translation:Humans
  10. Doty DT, Schueler J, Mott VL, Bryan CM, Moore NF, Ho JC, Borenstein JT. Modeling Immune Checkpoint Inhibitor Efficacy in Syngeneic Mouse Tumors in an Ex Vivo Immuno-Oncology Dynamic Environment. Int J Mol Sci. 2020 Sep 04; 21(18). PMID: 32899865.
    Citations: 2     Fields:    Translation:AnimalsCells
  11. Moore N, Chevillet JR, Healey LJ, McBrine C, Doty D, Santos J, Teece B, Truslow J, Mott V, Hsi P, Tandon V, Borenstein JT, Balestrini J, Kotz K. A Microfluidic Device to Enhance Viral Transduction Efficiency During Manufacture of Engineered Cellular Therapies. Sci Rep. 2019 10 22; 9(1):15101. PMID: 31641163.
    Citations: 3     Fields:    Translation:HumansCells
  12. Beckwith AL, Velásquez-García LF, Borenstein JT. Microfluidic Model for Evaluation of Immune Checkpoint Inhibitors in Human Tumors. Adv Healthc Mater. 2019 06; 8(11):e1900289. PMID: 31056856.
    Citations: 7     Fields:    Translation:Humans
  13. Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT. Intracochlear drug delivery: Fluorescent tracer evaluation for quantification of distribution in the cochlear partition. Eur J Pharm Sci. 2019 Jan 01; 126:49-58. PMID: 30195649.
    Citations: 1     Fields:    Translation:AnimalsCells
  14. Bale SS, Borenstein JT. Microfluidic Cell Culture Platforms to Capture Hepatic Physiology and Complex Cellular Interactions. Drug Metab Dispos. 2018 11; 46(11):1638-1646. PMID: 30115643.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  15. Moore N, Doty D, Zielstorff M, Kariv I, Moy LY, Gimbel A, Chevillet JR, Lowry N, Santos J, Mott V, Kratchman L, Lau T, Addona G, Chen H, Borenstein JT. A multiplexed microfluidic system for evaluation of dynamics of immune-tumor interactions. Lab Chip. 2018 06 26; 18(13):1844-1858. PMID: 29796561.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  16. Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT. A fluorescence-based imaging approach to pharmacokinetic analysis of intracochlear drug delivery. Hear Res. 2018 10; 368:41-48. PMID: 29661614.
    Citations: 3     Fields:    Translation:AnimalsCells
  17. Peppi M, Marie A, Belline C, Borenstein JT. Intracochlear drug delivery systems: a novel approach whose time has come. Expert Opin Drug Deliv. 2018 04; 15(4):319-324. PMID: 29480039.
    Citations: 7     Fields:    
  18. Xiao S, Coppeta JR, Rogers HB, Isenberg BC, Zhu J, Olalekan SA, McKinnon KE, Dokic D, Rashedi AS, Haisenleder DJ, Malpani SS, Arnold-Murray CA, Chen K, Jiang M, Bai L, Nguyen CT, Zhang J, Laronda MM, Hope TJ, Maniar KP, Pavone ME, Avram MJ, Sefton EC, Getsios S, Burdette JE, Kim JJ, Borenstein JT, Woodruff TK. A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. Nat Commun. 2017 03 28; 8:14584. PMID: 28350383; PMCID: PMC5379057.
    Citations: 120     Fields:    Translation:HumansAnimals
  19. Yesilyurt V, Ayoob AM, Appel EA, Borenstein JT, Langer R, Anderson DG. Mixed Reversible Covalent Crosslink Kinetics Enable Precise, Hierarchical Mechanical Tuning of Hydrogel Networks. Adv Mater. 2017 May; 29(19). PMID: 28295624.
    Citations: 13     Fields:    
  20. Coppeta JR, Mescher MJ, Isenberg BC, Spencer AJ, Kim ES, Lever AR, Mulhern TJ, Prantil-Baun R, Comolli JC, Borenstein JT. A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control. Lab Chip. 2016 12 20; 17(1):134-144. PMID: 27901159.
    Citations: 22     Fields:    Translation:HumansCells
  21. Hoganson DM, Finkelstein EB, Owens GE, Hsiao JC, Eng KY, Kulig KM, Kim ES, Kniazeva T, Pomerantseva I, Neville CM, Turk JR, Fermini B, Borenstein JT, Vacanti JP. A bilayer small diameter in vitro vascular model for evaluation of drug induced vascular injury. Biomicrofluidics. 2016 Sep; 10(5):054116. PMID: 27795748; PMCID: PMC5065573.
    Citations: 2     
  22. Gimbel AA, Flores E, Koo A, García-Cardeña G, Borenstein JT. Development of a biomimetic microfluidic oxygen transfer device. Lab Chip. 2016 08 16; 16(17):3227-34. PMID: 27411972.
    Citations: 4     Fields:    Translation:HumansCells
  23. Tandon V, Kang WS, Robbins TA, Spencer AJ, Kim ES, McKenna MJ, Kujawa SG, Fiering J, Pararas EE, Mescher MJ, Sewell WF, Borenstein JT. Microfabricated reciprocating micropump for intracochlear drug delivery with integrated drug/fluid storage and electronically controlled dosing. Lab Chip. 2016 Mar 07; 16(5):829-46. PMID: 26778829; PMCID: PMC4766044.
    Citations: 14     Fields:    Translation:HumansAnimals
  24. Borenstein JT. Organs-on-Chips: How Microsystems Technology Can Transform the Drug Development Process. IEEE Pulse. 2016 Mar-Apr; 7(2):22-6. PMID: 26978847.
    Citations: 3     Fields:    Translation:HumansAnimals
  25. Rivera-Burgos D, Sarkar U, Lever AR, Avram MJ, Coppeta JR, Wishnok JS, Borenstein JT, Tannenbaum SR. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. Drug Metab Dispos. 2016 Feb; 44(2):220-6. PMID: 26586376; PMCID: PMC4727117.
    Citations: 3     Fields:    Translation:HumansCells
  26. Lever AR, Park H, Mulhern TJ, Jackson GR, Comolli JC, Borenstein JT, Hayden PJ, Prantil-Baun R. Comprehensive evaluation of poly(I:C) induced inflammatory response in an airway epithelial model. Physiol Rep. 2015 Apr; 3(4). PMID: 25847914.
    Citations: 18     Fields:    
  27. Tandon V, Kang WS, Spencer AJ, Kim ES, Pararas EE, McKenna MJ, Kujawa SG, Mescher MJ, Fiering J, Sewell WF, Borenstein JT. Microfabricated infuse-withdraw micropump component for an integrated inner-ear drug-delivery platform. Biomed Microdevices. 2015 Apr; 17(2):37. PMID: 25686902.
    Citations: 4     Fields:    Translation:Animals
  28. Ayoob AM, Borenstein JT. The role of intracochlear drug delivery devices in the management of inner ear disease. Expert Opin Drug Deliv. 2015 Mar; 12(3):465-79. PMID: 25347140.
    Citations: 10     Fields:    Translation:Humans
  29. Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A. A microphysiological system model of therapy for liver micrometastases. Exp Biol Med (Maywood). 2014 Sep; 239(9):1170-9. PMID: 24821820.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  30. Ebrahimkhani MR, Young CL, Lauffenburger DA, Griffith LG, Borenstein JT. Approaches to in vitro tissue regeneration with application for human disease modeling and drug development. Drug Discov Today. 2014 Jun; 19(6):754-62. PMID: 24793141.
    Citations: 16     Fields:    Translation:HumansAnimals
  31. Kim ES, Gustenhoven E, Mescher MJ, Pararas EE, Smith KA, Spencer AJ, Tandon V, Borenstein JT, Fiering J. A microfluidic reciprocating intracochlear drug delivery system with reservoir and active dose control. Lab Chip. 2014 Feb 21; 14(4):710-21. PMID: 24302432.
    Citations: 5     Fields:    Translation:Animals
  32. Wheeler SE, Borenstein JT, Clark AM, Ebrahimkhani MR, Fox IJ, Griffith L, Inman W, Lauffenburger D, Nguyen T, Pillai VC, Prantil-Baun R, Stolz DB, Taylor D, Ulrich T, Venkataramanan R, Wells A, Young C. All-human microphysical model of metastasis therapy. Stem Cell Res Ther. 2013; 4 Suppl 1:S11. PMID: 24565274.
    Citations: 16     Fields:    Translation:HumansCells
  33. Pereira MJ, Sundback CA, Lang N, Cho WK, Pomerantseva I, Ouyang B, Tao SL, McHugh K, Mwizerwa O, Vemula PK, Mochel MC, Carter DJ, Borenstein JT, Langer R, Ferreira LS, Karp JM, Masiakos PT. Combined surface micropatterning and reactive chemistry maximizes tissue adhesion with minimal inflammation. Adv Healthc Mater. 2014 Apr; 3(4):565-71. PMID: 24106240.
    Citations: 4     Fields:    Translation:Animals
  34. Frohlich EM, Alonso JL, Borenstein JT, Zhang X, Arnaout MA, Charest JL. Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers. Lab Chip. 2013 Jun 21; 13(12):2311-9. PMID: 23636129.
    Citations: 13     Fields:    Translation:HumansCells
  35. Zhang Z, Borenstein J, Guiney L, Miller R, Sukavaneshvar S, Loose C. Polybetaine modification of PDMS microfluidic devices to resist thrombus formation in whole blood. Lab Chip. 2013 May 21; 13(10):1963-8. PMID: 23563730.
    Citations: 7     Fields:    Translation:AnimalsCells
  36. Wang J, Boutin KG, Abdulhadi O, Personnat LD, Shazly T, Langer R, Channick CL, Borenstein JT. Fully biodegradable airway stents using amino alcohol-based poly(ester amide) elastomers. Adv Healthc Mater. 2013 Oct; 2(10):1329-36. PMID: 23526787.
    Citations: 3     Fields:    Translation:Animals
  37. Kniazeva T, Epshteyn AA, Hsiao JC, Kim ES, Kolachalama VB, Charest JL, Borenstein JT. Performance and scaling effects in a multilayer microfluidic extracorporeal lung oxygenation device. Lab Chip. 2012 May 07; 12(9):1686-95. PMID: 22418858.
    Citations: 17     Fields:    Translation:Humans
  38. Cohen SJ, Chan RV, Keegan M, Andreoli CM, Borenstein JT, Miller JW, Gragoudas ES. Evaluation of tissue interactions with mechanical elements of a transscleral drug delivery device. Pharmaceutics. 2012 Mar 12; 4(1):212-29. PMID: 24300189.
  39. Bellan LM, Kniazeva T, Kim ES, Epshteyn AA, Cropek DM, Langer R, Borenstein JT. Fabrication of a hybrid microfluidic system incorporating both lithographically patterned microchannels and a 3D fiber-formed microfluidic network. Adv Healthc Mater. 2012 Mar; 1(2):164-7. PMID: 22708076.
    Citations: 6     Fields:    
  40. Eda H, Kulig KM, Steiner TA, Shimada H, Patel K, Park E, Kim ES, Borenstein JT, Neville CM, Keller BT. A nanofiber membrane maintains the quiescent phenotype of hepatic stellate cells. Dig Dis Sci. 2012 May; 57(5):1152-62. PMID: 22359192.
    Citations: 1     Fields:    Translation:AnimalsCells
  41. Pararas EE, Borkholder DA, Borenstein JT. Microsystems technologies for drug delivery to the inner ear. Adv Drug Deliv Rev. 2012 Nov; 64(14):1650-60. PMID: 22386561.
    Citations: 11     Fields:    Translation:HumansAnimals
  42. Borenstein JT, Vunjak-Novakovic G. Engineering tissue with BioMEMS. IEEE Pulse. 2011 Nov; 2(6):28-34. PMID: 22147066.
    Citations: 6     Fields:    Translation:Humans
  43. Epshteyn AA, Maher S, Taylor AJ, Holton AB, Borenstein JT, Cuiffi JD. Membrane-integrated microfluidic device for high-resolution live cell imaging. Biomicrofluidics. 2011 Dec; 5(4):46501-465016. PMID: 22662065.
    Citations: 10     
  44. Inamdar NK, Borenstein JT. Microfluidic cell culture models for tissue engineering. Curr Opin Biotechnol. 2011 Oct; 22(5):681-9. PMID: 21723720.
    Citations: 39     Fields:    Translation:HumansAnimals
  45. Inamdar NK, Griffith LG, Borenstein JT. Transport and shear in a microfluidic membrane bilayer device for cell culture. Biomicrofluidics. 2011 Jun; 5(2):22213. PMID: 21799719.
    Citations: 6     
  46. Borenstein JT. Intracochlear drug delivery systems. Expert Opin Drug Deliv. 2011 Sep; 8(9):1161-74. PMID: 21615213.
    Citations: 16     Fields:    Translation:HumansAnimals
  47. Kniazeva T, Hsiao JC, Charest JL, Borenstein JT. A microfluidic respiratory assist device with high gas permeance for artificial lung applications. Biomed Microdevices. 2011 Apr; 13(2):315-23. PMID: 21113664.
    Citations: 26     Fields:    
  48. Pararas EE, Chen Z, Fiering J, Mescher MJ, Kim ES, McKenna MJ, Kujawa SG, Borenstein JT, Sewell WF. Kinetics of reciprocating drug delivery to the inner ear. J Control Release. 2011 Jun 10; 152(2):270-7. PMID: 21385596.
    Citations: 13     Fields:    Translation:AnimalsCells
  49. Wang J, Bettinger CJ, Langer RS, Borenstein JT. Biodegradable microfluidic scaffolds for tissue engineering from amino alcohol-based poly(ester amide) elastomers. Organogenesis. 2010 Oct-Dec; 6(4):212-6. PMID: 21220957.
    Citations: 13     Fields:    
  50. Hsu WM, Carraro A, Kulig KM, Miller ML, Kaazempur-Mofrad M, Weinberg E, Entabi F, Albadawi H, Watkins MT, Borenstein JT, Vacanti JP, Neville C. Liver-assist device with a microfluidics-based vascular bed in an animal model. Ann Surg. 2010 Aug; 252(2):351-7. PMID: 20647924.
    Citations: 6     Fields:    Translation:AnimalsCells
  51. Hoganson DM, Anderson JL, Weinberg EF, Swart E, Swart EJ, Orrick BK, Borenstein JT, Vacanti JP. Branched vascular network architecture: a new approach to lung assist device technology. J Thorac Cardiovasc Surg. 2010 Nov; 140(5):990-5. PMID: 20591445.
    Citations: 10     Fields:    Translation:Animals
  52. McCall AA, Swan EE, Borenstein JT, Sewell WF, Kujawa SG, McKenna MJ. Drug delivery for treatment of inner ear disease: current state of knowledge. Ear Hear. 2010 Apr; 31(2):156-65. PMID: 19952751.
    Citations: 46     Fields:    Translation:Humans
  53. Borenstein JT, Tupper MM, Mack PJ, Weinberg EJ, Khalil AS, Hsiao J, García-Cardeña G. Functional endothelialized microvascular networks with circular cross-sections in a tissue culture substrate. Biomed Microdevices. 2010 Feb; 12(1):71-9. PMID: 19787455.
    Citations: 41     Fields:    Translation:HumansCells
  54. Bettinger CJ, Bruggeman JP, Borenstein JT, Langer R. In vitro and in vivo degradation of poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate) elastomers. J Biomed Mater Res A. 2009 Dec 15; 91(4):1077-88. PMID: 19107786.
    Citations: 11     Fields:    Translation:Animals
  55. Sewell WF, Borenstein JT, Chen Z, Fiering J, Handzel O, Holmboe M, Kim ES, Kujawa SG, McKenna MJ, Mescher MM, Murphy B, Swan EE, Peppi M, Tao S. Development of a microfluidics-based intracochlear drug delivery device. Audiol Neurootol. 2009; 14(6):411-22. PMID: 19923811.
    Citations: 18     Fields:    Translation:Animals
  56. Fritsche CS, Simsch O, Weinberg EJ, Orrick B, Stamm C, Kaazempur-Mofrad MR, Borenstein JT, Hetzer R, Vacanti JP. Pulmonary tissue engineering using dual-compartment polymer scaffolds with integrated vascular tree. Int J Artif Organs. 2009 Oct; 32(10):701-10. PMID: 19943231.
    Citations: 10     Fields:    Translation:AnimalsCells
  57. Freed LE, Engelmayr GC, Borenstein JT, Moutos FT, Guilak F. Advanced material strategies for tissue engineering scaffolds. Adv Mater. 2009 Sep 04; 21(32-33):3410-8. PMID: 20882506.
    Citations: 49     Fields:    
  58. Kendler DL, Bessette L, Hill CD, Gold DT, Horne R, Varon SF, Borenstein J, Wang H, Man HS, Wagman RB, Siddhanti S, Macarios D, Bone HG. Preference and satisfaction with a 6-month subcutaneous injection versus a weekly tablet for treatment of low bone mass. Osteoporos Int. 2010 May; 21(5):837-46. PMID: 19657689.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  59. Fiering J, Mescher MJ, Leary Swan EE, Holmboe ME, Murphy BA, Chen Z, Peppi M, Sewell WF, McKenna MJ, Kujawa SG, Borenstein JT. Local drug delivery with a self-contained, programmable, microfluidic system. Biomed Microdevices. 2009 Jun; 11(3):571-8. PMID: 19089621.
    Citations: 16     Fields:    Translation:AnimalsCells
  60. Bettinger CJ, Kulig KM, Vacanti JP, Langer R, Borenstein JT. Nanofabricated collagen-inspired synthetic elastomers for primary rat hepatocyte culture. Tissue Eng Part A. 2009 Jun; 15(6):1321-9. PMID: 18847357.
    Citations: 9     Fields:    Translation:AnimalsCells
  61. Mescher MJ, Swan EE, Fiering J, Holmboe ME, Sewell WF, Kujawa SG, McKenna MJ, Borenstein JT. Fabrication Methods and Performance of Low-Permeability Microfluidic Components for a Miniaturized Wearable Drug Delivery System. J Microelectromech Syst. 2009 Jun 01; 18(3):501-510. PMID: 20852729.
    Citations: 12     
  62. Handzel O, Wang H, Fiering J, Borenstein JT, Mescher MJ, Swan EE, Murphy BA, Chen Z, Peppi M, Sewell WF, Kujawa SG, McKenna MJ. Mastoid cavity dimensions and shape: method of measurement and virtual fitting of implantable devices. Audiol Neurootol. 2009; 14(5):308-14. PMID: 19372649.
    Citations: 9     Fields:    Translation:Humans
  63. Ciocan R, Lenkinski RE, Bernstein J, Bancu M, Marquis R, Ivanishev A, Kourtelidis F, Matsui A, Borenstein J, Frangioni JV. MRI contrast using solid-state, B1-distorting, microelectromechanical systems (MEMS) microresonant devices (MRDs). Magn Reson Med. 2009 Apr; 61(4):860-6. PMID: 19189289.
    Citations: 2     Fields:    Translation:Animals
  64. Bettinger CJ, Bruggeman JP, Misra A, Borenstein JT, Langer R. Biocompatibility of biodegradable semiconducting melanin films for nerve tissue engineering. Biomaterials. 2009 Jun; 30(17):3050-7. PMID: 19286252.
    Citations: 43     Fields:    Translation:AnimalsCellsPHPublic Health
  65. Bettinger CJ, Langer R, Borenstein JT. Engineering substrate topography at the micro- and nanoscale to control cell function. Angew Chem Int Ed Engl. 2009; 48(30):5406-15. PMID: 19492373.
    Citations: 251     Fields:    Translation:HumansCells
  66. Du Y, Shim J, Vidula M, Hancock MJ, Lo E, Chung BG, Borenstein JT, Khabiry M, Cropek DM, Khademhosseini A. Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device. Lab Chip. 2009 Mar 21; 9(6):761-7. PMID: 19255657.
    Citations: 25     Fields:    Translation:AnimalsCells
  67. Borenstein JT. Acting together, bacterial clusters initiate coagulation. Nat Chem Biol. 2008 Dec; 4(12):718-9. PMID: 19008879.
    Citations:    Fields:    Translation:Humans
  68. Carraro A, Hsu WM, Kulig KM, Cheung WS, Miller ML, Weinberg EJ, Swart EF, Kaazempur-Mofrad M, Borenstein JT, Vacanti JP, Neville C. In vitro analysis of a hepatic device with intrinsic microvascular-based channels. Biomed Microdevices. 2008 Dec; 10(6):795-805. PMID: 18604585.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  69. Engelmayr GC, Cheng M, Bettinger CJ, Borenstein JT, Langer R, Freed LE. Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat Mater. 2008 Dec; 7(12):1003-10. PMID: 18978786.
    Citations: 224     Fields:    Translation:Animals
  70. Swan EE, Mescher MJ, Sewell WF, Tao SL, Borenstein JT. Inner ear drug delivery for auditory applications. Adv Drug Deliv Rev. 2008 Dec 14; 60(15):1583-99. PMID: 18848590; PMCID: PMC2657604.
    Citations: 63     Fields:    Translation:HumansAnimals
  71. Weinberg E, Kaazempur-Mofrad M, Borenstein J. Concept and computational design for a bioartificial nephron-on-a-chip. Int J Artif Organs. 2008 Jun; 31(6):508-14. PMID: 18609503.
    Citations: 10     Fields:    
  72. Bettinger CJ, Bruggeman JP, Borenstein JT, Langer RS. Amino alcohol-based degradable poly(ester amide) elastomers. Biomaterials. 2008 May; 29(15):2315-25. PMID: 18295329.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  73. Mahdavi A, Ferreira L, Sundback C, Nichol JW, Chan EP, Carter DJ, Bettinger CJ, Patanavanich S, Chignozha L, Ben-Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos PT, Faquin W, Zumbuehl A, Hong S, Borenstein J, Vacanti J, Langer R, Karp JM. A biodegradable and biocompatible gecko-inspired tissue adhesive. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2307-12. PMID: 18287082.
    Citations: 83     Fields:    Translation:AnimalsCells
  74. Bettinger CJ, Zhang Z, Gerecht S, Borenstein JT, Langer R. Enhancement of In Vitro Capillary Tube Formation by Substrate Nanotopography. Adv Mater. 2008; 20(1):99-103. PMID: 19440248.
    Citations: 49     Fields:    
  75. Carlen ET, Weinberg MS, Zapata AM, Borenstein JT. A micromachined surface stress sensor with electronic readout. Rev Sci Instrum. 2008 Jan; 79(1):015106. PMID: 18248065.
    Citations:    Fields:    
  76. Borenstein JT, Weinberg EJ, Orrick BK, Sundback C, Kaazempur-Mofrad MR, Vacanti JP. Microfabrication of three-dimensional engineered scaffolds. Tissue Eng. 2007 Aug; 13(8):1837-44. PMID: 17590149.
    Citations: 42     Fields:    Translation:HumansAnimals
  77. Gerecht S, Bettinger CJ, Zhang Z, Borenstein JT, Vunjak-Novakovic G, Langer R. The effect of actin disrupting agents on contact guidance of human embryonic stem cells. Biomaterials. 2007 Oct; 28(28):4068-77. PMID: 17576011.
    Citations: 69     Fields:    Translation:HumansCells
  78. Karp JM, Yeh J, Eng G, Fukuda J, Blumling J, Suh KY, Cheng J, Mahdavi A, Borenstein J, Langer R, Khademhosseini A. Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip. 2007 Jun; 7(6):786-94. PMID: 17538722.
    Citations: 101     Fields:    Translation:HumansCells
  79. Bettinger CJ, Cyr KM, Matsumoto A, Langer R, Borenstein JT, Kaplan DL. Silk Fibroin Microfluidic Devices. Adv Mater. 2007; 19(5):2847-2850. PMID: 19424448.
    Citations: 37     Fields:    
  80. Blumenthal PD, Trussell J, Singh RH, Guo A, Borenstein J, Dubois RW, Liu Z. Cost-effectiveness of treatments for dysfunctional uterine bleeding in women who need contraception. Contraception. 2006 Sep; 74(3):249-58. PMID: 16904420.
    Citations: 5     Fields:    Translation:Humans
  81. Khademhosseini A, Langer R, Borenstein J, Vacanti JP. Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2480-7. PMID: 16477028; PMCID: PMC1413775.
    Citations: 381     Fields:    Translation:HumansAnimals
  82. Khademhosseini A, Bettinger C, Karp JM, Yeh J, Ling Y, Borenstein J, Fukuda J, Langer R. Interplay of biomaterials and micro-scale technologies for advancing biomedical applications. J Biomater Sci Polym Ed. 2006; 17(11):1221-40. PMID: 17176747.
    Citations: 12     Fields:    Translation:Cells
  83. Bettinger CJ, Orrick B, Misra A, Langer R, Borenstein JT. Microfabrication of poly (glycerol-sebacate) for contact guidance applications. Biomaterials. 2006 Apr; 27(12):2558-65. PMID: 16386300.
    Citations: 50     Fields:    Translation:AnimalsCells
  84. Bettinger CJ, Weinberg EJ, Kulig KM, Vacanti JP, Wang Y, Borenstein JT, Langer R. Three-Dimensional Microfluidic Tissue-Engineering Scaffolds Using a Flexible Biodegradable Polymer. Adv Mater. 2005 Dec 08; 18(2):165-169. PMID: 19759845.
    Citations: 51     Fields:    
  85. Chen Z, Kujawa SG, McKenna MJ, Fiering JO, Mescher MJ, Borenstein JT, Swan EE, Sewell WF. Inner ear drug delivery via a reciprocating perfusion system in the guinea pig. J Control Release. 2005 Dec 10; 110(1):1-19. PMID: 16274830.
    Citations: 41     Fields:    Translation:AnimalsCells
  86. Khademhosseini A, Yeh J, Eng G, Karp J, Kaji H, Borenstein J, Farokhzad OC, Langer R. Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab Chip. 2005 Dec; 5(12):1380-6. PMID: 16286969.
    Citations: 52     Fields:    
  87. Fidkowski C, Kaazempur-Mofrad MR, Borenstein J, Vacanti JP, Langer R, Wang Y. Endothelialized microvasculature based on a biodegradable elastomer. Tissue Eng. 2005 Jan-Feb; 11(1-2):302-9. PMID: 15738683.
    Citations: 87     Fields:    Translation:HumansCellsPHPublic Health
  88. Shin M, Matsuda K, Ishii O, Terai H, Kaazempur-Mofrad M, Borenstein J, Detmar M, Vacanti JP. Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane). Biomed Microdevices. 2004 Dec; 6(4):269-78. PMID: 15548874.
    Citations: 58     Fields:    Translation:HumansCells
  89. Ogawa K, Ochoa ER, Borenstein J, Tanaka K, Vacanti JP. The generation of functionally differentiated, three-dimensional hepatic tissue from two-dimensional sheets of progenitor small hepatocytes and nonparenchymal cells. Transplantation. 2004 Jun 27; 77(12):1783-9. PMID: 15223892.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  90. Rodby RA, Chiou CF, Borenstein J, Smitten A, Sengupta N, Palmer AJ, Roze S, Annemans L, Simon TA, Chen RS, Lewis EJ. The cost-effectiveness of irbesartan in the treatment of hypertensive patients with type 2 diabetic nephropathy. Clin Ther. 2003 Jul; 25(7):2102-19. PMID: 12946554.
    Citations: 17     Fields:    Translation:Humans
  91. Borenstein J, Yu HT, Wade S, Chiou CF, Rapkin A. Effect of an oral contraceptive containing ethinyl estradiol and drospirenone on premenstrual symptomatology and health-related quality of life. J Reprod Med. 2003 Feb; 48(2):79-85. PMID: 12621790.
    Citations: 10     Fields:    Translation:Humans
  92. Kaihara S, Borenstein J, Koka R, Lalan S, Ochoa ER, Ravens M, Pien H, Cunningham B, Vacanti JP. Silicon micromachining to tissue engineer branched vascular channels for liver fabrication. Tissue Eng. 2000 Apr; 6(2):105-17. PMID: 10941206.
    Citations: 51     Fields:    Translation:AnimalsCells
  93. Levine SP, Bell DA, Jaros LA, Simpson RC, Koren Y, Borenstein J. The NavChair Assistive Wheelchair Navigation System. IEEE Trans Rehabil Eng. 1999 Dec; 7(4):443-51. PMID: 10609632.
    Citations: 13     Fields:    Translation:Humans
  94. Atad J, Hallak M, Fruchter O, Borenstein J, Abramovici H. Second-trimester membrane rupture. Abortion induced with prostaglandin E2 after oxytocin failure. J Reprod Med. 1997 Sep; 42(9):581-4. PMID: 9336755.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.