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profileMaria Tsokos, M.D.

TitleProfessor in Residence of Medicine
InstitutionBeth Israel Deaconess Medical Center
DepartmentMedicine
AddressBeth Israel Deaconess Medical Center
Medicine - Dana 517
330 Brookline Ave
Boston MA 02215
Phone617/667-2464
Fax617/667-2785
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Satyam A, Kannan L, Matsumoto N, Geha M, Lapchak PH, Bosse R, Shi GP, Dalle Lucca JJ, Tsokos MG, Tsokos GC. Intracellular Activation of Complement 3 Is Responsible for Intestinal Tissue Damage during Mesenteric Ischemia. J Immunol. 2017 Jan 15; 198(2):788-797. PMID: 27913632.
    View in: PubMed
  2. Long AH, Highfill SL, Cui Y, Smith JP, Walker AJ, Ramakrishna S, El-Etriby R, Galli S, Tsokos MG, Orentas RJ, Mackall CL. Reduction of MDSCs with All-trans Retinoic Acid Improves CAR Therapy Efficacy for Sarcomas. Cancer Immunol Res. 2016 Oct; 4(10):869-880. PMID: 27549124.
    View in: PubMed
  3. Apostolidis SA, Rodríguez-Rodríguez N, Suárez-Fueyo A, Dioufa N, Ozcan E, Crispín JC, Tsokos MG, Tsokos GC. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016 May; 17(5):556-64. PMID: 26974206; PMCID: PMC4837024.
  4. Marchegiani S, Davis T, Tessadori F, van Haaften G, Brancati F, Hoischen A, Huang H, Valkanas E, Pusey B, Schanze D, Venselaar H, Vulto-van Silfhout AT, Wolfe LA, Tifft CJ, Zerfas PM, Zambruno G, Kariminejad A, Sabbagh-Kermani F, Lee J, Tsokos MG, Lee CC, Ferraz V, da Silva EM, Stevens CA, Roche N, Bartsch O, Farndon P, Bermejo-Sanchez E, Brooks BP, Maduro V, Dallapiccola B, Ramos FJ, Chung HY, Le Caignec C, Martins F, Jacyk WK, Mazzanti L, Brunner HG, Bakkers J, Lin S, Malicdan MC, Boerkoel CF, Gahl WA, de Vries BB, van Haelst MM, Zenker M, Markello TC. Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes. Am J Hum Genet. 2015 Jul 02; 97(1):99-110. PMID: 26119818; PMCID: PMC4572501.
  5. Kalra N, Zhang J, Thomas A, Xi L, Cheung M, Talarchek J, Burkett S, Tsokos MG, Chen Y, Raffeld M, Miettinen M, Pastan I, Testa JR, Hassan R. Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma. BMC Cancer. 2015 May 08; 15:376. PMID: 25952750; PMCID: PMC4431029.
  6. Szarek E, Ball ER, Imperiale A, Tsokos M, Faucz FR, Giubellino A, Moussallieh FM, Namer IJ, Abu-Asab MS, Pacak K, Taïeb D, Carney JA, Stratakis CA. Carney triad, SDH-deficient tumors, and Sdhb+/- mice share abnormal mitochondria. Endocr Relat Cancer. 2015 Jun; 22(3):345-52. PMID: 25808178; PMCID: PMC4433412.
  7. Kahn J, Gillespie A, Tsokos M, Ondos J, Dombi E, Camphausen K, Widemann BC, Kaushal A. Radiation therapy in management of sporadic and neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors. Front Oncol. 2014; 4:324. PMID: 25452937; PMCID: PMC4233912.
  8. Muroya T, Kannan L, Ghiran IC, Shevkoplyas SS, Paz Z, Tsokos M, Dalle Lucca JJ, Shapiro NI, Tsokos GC. C4d deposits on the surface of RBCs in trauma patients and interferes with their function. Crit Care Med. 2014 May; 42(5):e364-72. PMID: 24448198; PMCID: PMC4099476.
  9. Arnold MA, Ballester LY, Pack SD, Abdullaev Z, Merchant M, Tsokos MG. Primary subcutaneous spindle cell Ewing sarcoma with strong S100 expression and EWSR1-FLI1 fusion: a case report. Pediatr Dev Pathol. 2014 Jul-Aug; 17(4):302-7. PMID: 24735198.
    View in: PubMed
  10. Alimchandani M, Lara K, Tsokos M, Linehan WM, Merino MJ. Lymphangitic retroperitoneal carcinomatosis occurring from metastatic sarcomatoid chromophobe renal cell carcinoma. Urol Case Rep. 2014 Mar 01; 2(2):39-62. PMID: 24696789.
    View in: PubMed
  11. Hermanns MI, Müller AM, Tsokos M, Kirkpatrick CJ. LPS-induced effects on angiotensin I-converting enzyme expression and shedding in human pulmonary microvascular endothelial cells. In Vitro Cell Dev Biol Anim. 2014 Apr; 50(4):287-95. PMID: 24165975.
    View in: PubMed
  12. Manoli I, Sysol JR, Li L, Houillier P, Garone C, Wang C, Zerfas PM, Cusmano-Ozog K, Young S, Trivedi NS, Cheng J, Sloan JL, Chandler RJ, Abu-Asab M, Tsokos M, Elkahloun AG, Rosen S, Enns GM, Berry GT, Hoffmann V, DiMauro S, Schnermann J, Venditti CP. Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13552-7. PMID: 23898205; PMCID: PMC3746875.
  13. Lai JP, Liu YC, Alimchandani M, Liu Q, Aung PP, Matsuda K, Lee CC, Tsokos M, Hewitt S, Rushing EJ, Tamura D, Levens DL, Digiovanna JJ, Fine HA, Patronas N, Khan SG, Kleiner DE, Oberholtzer JC, Quezado MM, Kraemer KH. The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D). Acta Neuropathol Commun. 2013 May 08; 1:4. PMID: 24252196; PMCID: PMC3776212.
  14. Kleber C, Giesecke MT, Tsokos M, Haas NP, Buschmann CT. Trauma-related preventable deaths in Berlin 2010: need to change prehospital management strategies and trauma management education. World J Surg. 2013 May; 37(5):1154-61. PMID: 23430005.
    View in: PubMed
  15. Killian JK, Kim SY, Miettinen M, Smith C, Merino M, Tsokos M, Quezado M, Smith WI, Jahromi MS, Xekouki P, Szarek E, Walker RL, Lasota J, Raffeld M, Klotzle B, Wang Z, Jones L, Zhu Y, Wang Y, Waterfall JJ, O'Sullivan MJ, Bibikova M, Pacak K, Stratakis C, Janeway KA, Schiffman JD, Fan JB, Helman L, Meltzer PS. Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. Cancer Discov. 2013 Jun; 3(6):648-57. PMID: 23550148; PMCID: PMC4135374.
  16. Liu Q, Galli S, Srinivasan R, Linehan WM, Tsokos M, Merino MJ. Renal medullary carcinoma: molecular, immunohistochemistry, and morphologic correlation. Am J Surg Pathol. 2013 Mar; 37(3):368-74. PMID: 23348212.
    View in: PubMed
  17. Manoli I, Kwan JY, Wang Q, Rushing EJ, Tsokos M, Arai AE, Burch WM, Dispenzieri A, McPherron AC, Gahl WA. Chronic myopathy due to immunoglobulin light chain amyloidosis. Mol Genet Metab. 2013 Apr; 108(4):249-54. PMID: 23465863; PMCID: PMC3608108.
  18. Tobin LA, Xie Y, Tsokos M, Chung SI, Merz AA, Arnold MA, Li G, Malech HL, Kwong KF. Pegylated siRNA-loaded calcium phosphate nanoparticle-driven amplification of cancer cell internalization in vivo. Biomaterials. 2013 Apr; 34(12):2980-90. PMID: 23369215; PMCID: PMC3633203.
  19. Arnold MA, Arnold CA, Li G, Chae U, El-Etriby R, Lee CC, Tsokos M. A unique pattern of INI1 immunohistochemistry distinguishes synovial sarcoma from its histologic mimics. Hum Pathol. 2013 May; 44(5):881-7. PMID: 23245672.
    View in: PubMed
  20. Martin-Manso G, Navarathna DH, Galli S, Soto-Pantoja DR, Kuznetsova SA, Tsokos M, Roberts DD. Endogenous thrombospondin-1 regulates leukocyte recruitment and activation and accelerates death from systemic candidiasis. PLoS One. 2012; 7(11):e48775. PMID: 23144964; PMCID: PMC3492437.
  21. Merchant MS, Geller JI, Baird K, Chou AJ, Galli S, Charles A, Amaoko M, Rhee EH, Price A, Wexler LH, Meyers PA, Widemann BC, Tsokos M, Mackall CL. Phase I trial and pharmacokinetic study of lexatumumab in pediatric patients with solid tumors. J Clin Oncol. 2012 Nov 20; 30(33):4141-7. PMID: 23071222; PMCID: PMC3494837.
  22. Soto-Pantoja DR, Miller TW, Pendrak ML, DeGraff WG, Sullivan C, Ridnour LA, Abu-Asab M, Wink DA, Tsokos M, Roberts DD. CD47 deficiency confers cell and tissue radioprotection by activation of autophagy. Autophagy. 2012 Nov; 8(11):1628-42. PMID: 22874555; PMCID: PMC3494592.
  23. Petrini I, Meltzer PS, Zucali PA, Luo J, Lee C, Santoro A, Lee HS, Killian KJ, Wang Y, Tsokos M, Roncalli M, Steinberg SM, Wang Y, Giaccone G. Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors. Cell Death Dis. 2012 Jul 19; 3:e351. PMID: 22825469; PMCID: PMC3406591.
  24. Gills JJ, Zhang C, Abu-Asab MS, Castillo SS, Marceau C, LoPiccolo J, Kozikowski AP, Tsokos M, Goldkorn T, Dennis PA. Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine. Cell Death Dis. 2012 Jul 05; 3:e340. PMID: 22764099; PMCID: PMC3406576.
  25. Meissner EG, Bennett JE, Qvarnstrom Y, da Silva A, Chu EY, Tsokos M, Gea-Banacloche J. Disseminated microsporidiosis in an immunosuppressed patient. Emerg Infect Dis. 2012 Jul; 18(7):1155-8. PMID: 22709509; PMCID: PMC3376806.
  26. Stauffer JK, Orentas RJ, Lincoln E, Khan T, Salcedo R, Hixon JA, Back TC, Wei JS, Patidar R, Song Y, Hurd L, Tsokos M, Lai EW, Eisenhofer G, Weiss W, Khan J, Wigginton JM. High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery. Cancer Invest. 2012 Jun; 30(5):343-63. PMID: 22571338.
    View in: PubMed
  27. Meany H, Dombi E, Reynolds J, Whatley M, Kurwa A, Tsokos M, Salzer W, Gillespie A, Baldwin A, Derdak J, Widemann B. 18-fluorodeoxyglucose-positron emission tomography (FDG-PET) evaluation of nodular lesions in patients with Neurofibromatosis type 1 and plexiform neurofibromas (PN) or malignant peripheral nerve sheath tumors (MPNST). Pediatr Blood Cancer. 2013 Jan; 60(1):59-64. PMID: 22645095.
    View in: PubMed
  28. Lai JP, Robbins PF, Raffeld M, Aung PP, Tsokos M, Rosenberg SA, Miettinen MM, Lee CC. NY-ESO-1 expression in synovial sarcoma and other mesenchymal tumors: significance for NY-ESO-1-based targeted therapy and differential diagnosis. Mod Pathol. 2012 Jun; 25(6):854-8. PMID: 22388761.
    View in: PubMed
  29. Hejna P, Zátopková L, Tsokos M. The diagnostic value of synovial membrane hemorrhage and bloody discoloration of synovial fluid ("inner knee sign") in autopsy cases of fatal hypothermia. Int J Legal Med. 2012 May; 126(3):415-9. PMID: 22349758.
    View in: PubMed
  30. Gochuico BR, Huizing M, Golas GA, Scher CD, Tsokos M, Denver SD, Frei-Jones MJ, Gahl WA. Interstitial lung disease and pulmonary fibrosis in Hermansky-Pudlak syndrome type 2, an adaptor protein-3 complex disease. Mol Med. 2012 Feb 10; 18:56-64. PMID: 22009278; PMCID: PMC3269640.
  31. Tsokos M, Alaggio RD, Dehner LP, Dickman PS. Ewing sarcoma/peripheral primitive neuroectodermal tumor and related tumors. Pediatr Dev Pathol. 2012; 15(1 Suppl):108-26. PMID: 22420726.
    View in: PubMed
  32. Meadors JL, Cui Y, Chen QR, Song YK, Khan J, Merlino G, Tsokos M, Orentas RJ, Mackall CL. Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy. Pediatr Blood Cancer. 2011 Dec 01; 57(6):921-9. PMID: 21462302.
    View in: PubMed
  33. Rame JE, Barouch LA, Sack MN, Lynn EG, Abu-Asab M, Tsokos M, Kern SJ, Barb JJ, Munson PJ, Halushka MK, Miller KL, Fox-Talbot K, Zhang J, Hare JM, Solomon MA, Danner RL. Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPAR{alpha}/PGC1{alpha} and thermogenic glycerolipid/fatty acid cycling. Physiol Genomics. 2011 Jun 28; 43(12):726-38. PMID: 21427359; PMCID: PMC3121158.
  34. Frazier EP, Isenberg JS, Shiva S, Zhao L, Schlesinger P, Dimitry J, Abu-Asab MS, Tsokos M, Roberts DD, Frazier WA. Age-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47. Matrix Biol. 2011 Mar; 30(2):154-61. PMID: 21256215; PMCID: PMC3070423.
  35. Yang Y, Valera VA, Padilla-Nash HM, Sourbier C, Vocke CD, Vira MA, Abu-Asab MS, Bratslavsky G, Tsokos M, Merino MJ, Pinto PA, Srinivasan R, Ried T, Neckers L, Linehan WM. UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer. Cancer Genet Cytogenet. 2010 Jan 01; 196(1):45-55. PMID: 19963135; PMCID: PMC2827193.
  36. Maxhimer JB, Soto-Pantoja DR, Ridnour LA, Shih HB, Degraff WG, Tsokos M, Wink DA, Isenberg JS, Roberts DD. Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling. Sci Transl Med. 2009 Oct 21; 1(3):3ra7. PMID: 20161613; PMCID: PMC2811586.
  37. Reid GS, Shan X, Coughlin CM, Lassoued W, Pawel BR, Wexler LH, Thiele CJ, Tsokos M, Pinkus JL, Pinkus GS, Grupp SA, Vonderheide RH. Interferon-gamma-dependent infiltration of human T cells into neuroblastoma tumors in vivo. Clin Cancer Res. 2009 Nov 01; 15(21):6602-8. PMID: 19825945; PMCID: PMC2783677.
  38. Fitzhugh CD, Wise B, Baird K, Tsokos M, Helman L, Mackall C, Savage SA, Warren KE. Secondary supratentorial primitive neuroectodermal tumor following treatment of childhood osteosarcoma. Pediatr Blood Cancer. 2009 Sep; 53(3):496-8. PMID: 19434734; PMCID: PMC2760453.
  39. Mochel F, Yang B, Barritault J, Thompson JN, Engelke UF, McNeill NH, Benko WS, Kaneski CR, Adams DR, Tsokos M, Abu-Asab M, Huizing M, Seguin F, Wevers RA, Ding J, Verheijen FW, Schiffmann R. Free sialic acid storage disease without sialuria. Ann Neurol. 2009 Jun; 65(6):753-7. PMID: 19557856; PMCID: PMC3508714.
  40. Li Q, Schurgers LJ, Smith AC, Tsokos M, Uitto J, Cowen EW. Co-existent pseudoxanthoma elasticum and vitamin K-dependent coagulation factor deficiency: compound heterozygosity for mutations in the GGCX gene. Am J Pathol. 2009 Feb; 174(2):534-40. PMID: 19116367; PMCID: PMC2630561.
  41. Timmers HJ, Pacak K, Huynh TT, Abu-Asab M, Tsokos M, Merino MJ, Baysal BE, Adams KT, Eisenhofer G. Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene. J Clin Endocrinol Metab. 2008 Dec; 93(12):4826-32. PMID: 18840642; PMCID: PMC2626451.
  42. Isenberg JS, Maxhimer JB, Hyodo F, Pendrak ML, Ridnour LA, DeGraff WG, Tsokos M, Wink DA, Roberts DD. Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury. Am J Pathol. 2008 Oct; 173(4):1100-12. PMID: 18787106; PMCID: PMC2543077.
  43. Isenberg JS, Maxhimer JB, Powers P, Tsokos M, Frazier WA, Roberts DD. Treatment of liver ischemia-reperfusion injury by limiting thrombospondin-1/CD47 signaling. Surgery. 2008 Nov; 144(5):752-61. PMID: 19081017; PMCID: PMC2635486.
  44. Martin-Manso G, Galli S, Ridnour LA, Tsokos M, Wink DA, Roberts DD. Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells. Cancer Res. 2008 Sep 01; 68(17):7090-9. PMID: 18757424; PMCID: PMC2562557.
  45. Mackall CL, Rhee EH, Read EJ, Khuu HM, Leitman SF, Bernstein D, Tesso M, Long LM, Grindler D, Merino M, Kopp W, Tsokos M, Berzofsky JA, Helman LJ. A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas. Clin Cancer Res. 2008 Aug 01; 14(15):4850-8. PMID: 18676758; PMCID: PMC2497450.
  46. Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A. 2008 Mar 04; 105(9):3374-9. PMID: 18296641; PMCID: PMC2265142.
  47. Lodish MB, Powell AC, Abu-Asab M, Cochran C, Lenz P, Libutti SK, Pingpank JF, Tsokos M, Gorden P. Insulinoma and gastrinoma syndromes from a single intrapancreatic neuroendocrine tumor. J Clin Endocrinol Metab. 2008 Apr; 93(4):1123-8. PMID: 18252785; PMCID: PMC2291484.
  48. Alesci S, Abu-Asab M, Perera SM, Tsokos M, Morris JC, Pacak K. Mitochondrial localization of human recombinant adenovirus: from evolution to gene therapy. Neuroimmunomodulation. 2007; 14(5):221-3. PMID: 18219224; PMCID: PMC2279234.
  49. Yang Y, Padilla-Nash HM, Vira MA, Abu-Asab MS, Val D, Worrell R, Tsokos M, Merino MJ, Pavlovich CP, Ried T, Linehan WM, Vocke CD. The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway. Cancer Genet Cytogenet. 2008 Jan 15; 180(2):100-9. PMID: 18206534; PMCID: PMC2440670.
  50. Kim SY, Tsokos M, Helman LJ. Dilemmas associated with congenital ewing sarcoma family tumors. J Pediatr Hematol Oncol. 2008 Jan; 30(1):4-7. PMID: 18176172; PMCID: PMC2668808.
  51. Isenberg JS, Pappan LK, Romeo MJ, Abu-Asab M, Tsokos M, Wink DA, Frazier WA, Roberts DD. Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts. Ann Surg. 2008 Jan; 247(1):180-90. PMID: 18156939; PMCID: PMC2432017.
  52. Isenberg JS, Hyodo F, Pappan LK, Abu-Asab M, Tsokos M, Krishna MC, Frazier WA, Roberts DD. Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia. Arterioscler Thromb Vasc Biol. 2007 Dec; 27(12):2582-8. PMID: 17916772.
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  53. Gills JJ, Lopiccolo J, Tsurutani J, Shoemaker RH, Best CJ, Abu-Asab MS, Borojerdi J, Warfel NA, Gardner ER, Danish M, Hollander MC, Kawabata S, Tsokos M, Figg WD, Steeg PS, Dennis PA. Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clin Cancer Res. 2007 Sep 01; 13(17):5183-94. PMID: 17785575.
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  54. Lissat A, Vraetz T, Tsokos M, Klein R, Braun M, Koutelia N, Fisch P, Romero ME, Long L, Noellke P, Mackall CL, Niemeyer CM, Kontny U. Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity. Am J Pathol. 2007 Jun; 170(6):1917-30. PMID: 17525260; PMCID: PMC1899433.
  55. Alesci S, Perera SM, Lai EW, Kukura C, Abu-Asab M, Tsokos M, Morris JC, Pacak K. Adenoviral gene transfer in bovine adrenomedullary and murine pheochromocytoma cells: potential clinical and therapeutic relevance. Endocrinology. 2007 Aug; 148(8):3900-7. PMID: 17525127; PMCID: PMC2527237.
  56. Ahmed AA, Tsokos M. Sinonasal rhabdomyosarcoma in children and young adults. Int J Surg Pathol. 2007 Apr; 15(2):160-5. PMID: 17478770.
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  57. Petricoin EF, Espina V, Araujo RP, Midura B, Yeung C, Wan X, Eichler GS, Johann DJ, Qualman S, Tsokos M, Krishnan K, Helman LJ, Liotta LA. Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res. 2007 Apr 01; 67(7):3431-40. PMID: 17409454.
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  58. Valencia JC, Rouzaud F, Julien S, Chen KG, Passeron T, Yamaguchi Y, Abu-Asab M, Tsokos M, Costin GE, Yamaguchi H, Jenkins LM, Nagashima K, Appella E, Hearing VJ. Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils. J Biol Chem. 2007 Apr 13; 282(15):11266-80. PMID: 17303571.
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  59. Isenberg JS, Romeo MJ, Abu-Asab M, Tsokos M, Oldenborg A, Pappan L, Wink DA, Frazier WA, Roberts DD. Increasing survival of ischemic tissue by targeting CD47. Circ Res. 2007 Mar 16; 100(5):712-20. PMID: 17293482.
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  60. Steel JC, Cavanagh HM, Burton MA, Abu-Asab MS, Tsokos M, Morris JC, Kalle WH. Increased tumor localization and reduced immune response to adenoviral vector formulated with the liposome DDAB/DOPE. Eur J Pharm Sci. 2007 Apr; 30(5):398-405. PMID: 17275269.
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  61. Timmons M, Tsokos M, Asab MA, Seminara SB, Zirzow GC, Kaneski CR, Heiss JD, van der Knaap MS, Vanier MT, Schiffmann R, Wong K. Peripheral and central hypomyelination with hypogonadotropic hypogonadism and hypodontia. Neurology. 2006 Dec 12; 67(11):2066-9. PMID: 17159124; PMCID: PMC1950601.
  62. Isenberg JS, Hyodo F, Matsumoto K, Romeo MJ, Abu-Asab M, Tsokos M, Kuppusamy P, Wink DA, Krishna MC, Roberts DD. Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation. Blood. 2007 Mar 01; 109(5):1945-52. PMID: 17082319; PMCID: PMC1801044.
  63. Ahmed AA, Nava VE, Pham T, Taubenberger JK, Lichy JH, Sorbara L, Raffeld M, Mackall CL, Tsokos M. Ewing sarcoma family of tumors in unusual sites: confirmation by rt-PCR. Pediatr Dev Pathol. 2006 Nov-Dec; 9(6):488-95. PMID: 17163788.
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  64. Michel RB, Abu-Asab M, Tsokos M, Mattes MJ. Characterization of antibody-containing vesicles shed from B-lymphoma cell lines: exposure of annexin V binding sites. Leuk Lymphoma. 2006 Nov; 47(11):2388-99. PMID: 17107914; PMCID: PMC2366172.
  65. Vortmeyer AO, Tran MG, Zeng W, Gläsker S, Riley C, Tsokos M, Ikejiri B, Merrill MJ, Raffeld M, Zhuang Z, Lonser RR, Maxwell PH, Oldfield EH. Evolution of VHL tumourigenesis in nerve root tissue. J Pathol. 2006 Nov; 210(3):374-82. PMID: 16981244.
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  66. Vishnyakova TG, Kurlander R, Bocharov AV, Baranova IN, Chen Z, Abu-Asab MS, Tsokos M, Malide D, Basso F, Remaley A, Csako G, Eggerman TL, Patterson AP. CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16888-93. PMID: 17071747; PMCID: PMC1636549.
  67. Schinstine M, Abati A, Tsokos M, Fox E, Filie AC. Cytological identification of metastatic epithelial nephroblastoma in pleural fluid: report of a case and review of literature. Diagn Cytopathol. 2006 Sep; 34(9):621-5. PMID: 16900470.
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  68. Ge Y, Montano I, Rustici G, Freebern WJ, Haggerty CM, Cui W, Ponciano-Jackson D, Chandramouli GV, Gardner ER, Figg WD, Abu-Asab M, Tsokos M, Jackson SH, Gardner K. Selective leukemic-cell killing by a novel functional class of thalidomide analogs. Blood. 2006 Dec 15; 108(13):4126-35. PMID: 16940421; PMCID: PMC1895447.
  69. Lee B, Galli S, Tsokos M. Sensitive Ewing sarcoma and neuroblastoma cell lines have increased levels of BAD expression and decreased levels of BAR expression compared to resistant cell lines. Cancer Lett. 2007 Mar 08; 247(1):110-4. PMID: 16690206.
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  70. Schiffmann R, Rapkiewicz A, Abu-Asab M, Ries M, Askari H, Tsokos M, Quezado M. Pathological findings in a patient with Fabry disease who died after 2.5 years of enzyme replacement. Virchows Arch. 2006 Mar; 448(3):337-43. PMID: 16315019; PMCID: PMC2288734.
  71. Türk EE, Sperhake JP, Madea B, Preuss J, Tsokos M. Immunohistochemical detection of hemoglobin in frost erythema. Forensic Sci Int. 2006 May 10; 158(2-3):131-4. PMID: 16024200.
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  72. Helman LJ, Yeung C, Espina V, Eichler G, Krishnan K, Tsokos M, Qualman S, Meyer W, Steinberg S, Petricoin EF, Liotta LA. Proteomic profiling identifies prognostic subsets in Rhabdomyosarcoma (RMS). J Clin Oncol. 2005 Jun; 23(16_suppl):9502. PMID: 27946696.
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  73. Nathan PC, Tsokos M, Long L, Bernstein D, Wexler LH, Mackall CL, Helman LJ. Adjuvant chemotherapy for the treatment of advanced pediatric nonrhabdomyosarcoma soft tissue sarcoma: the National Cancer Institute experience. Pediatr Blood Cancer. 2005 May; 44(5):449-54. PMID: 15547929.
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  74. Matyakhina L, Freedman RJ, Bourdeau I, Wei MH, Stergiopoulos SG, Chidakel A, Walther M, Abu-Asab M, Tsokos M, Keil M, Toro J, Linehan WM, Stratakis CA. Hereditary leiomyomatosis associated with bilateral, massive, macronodular adrenocortical disease and atypical cushing syndrome: a clinical and molecular genetic investigation. J Clin Endocrinol Metab. 2005 Jun; 90(6):3773-9. PMID: 15741255.
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  75. Barenboim-Stapleton L, Yang X, Tsokos M, Wigginton JM, Padilla-Nash H, Ried T, Thiele CJ. Pediatric pancreatoblastoma: histopathologic and cytogenetic characterization of tumor and derived cell line. Cancer Genet Cytogenet. 2005 Mar; 157(2):109-17. PMID: 15721631.
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  76. Merchant MS, Yang X, Melchionda F, Romero M, Klein R, Thiele CJ, Tsokos M, Kontny HU, Mackall CL. Interferon gamma enhances the effectiveness of tumor necrosis factor-related apoptosis-inducing ligand receptor agonists in a xenograft model of Ewing's sarcoma. Cancer Res. 2004 Nov 15; 64(22):8349-56. PMID: 15548704.
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  77. Maric I, Bryant R, Abu-Asab M, Cohen JI, Vivero A, Jaffe ES, Raffeld M, Tsokos M, Banks PM, Pittaluga S. Human herpesvirus-6-associated acute lymphadenitis in immunocompetent adults. Mod Pathol. 2004 Nov; 17(11):1427-33. PMID: 15494709; PMCID: PMC2288737.
  78. Bossis I, Voutetakis A, Matyakhina L, Pack S, Abu-Asab M, Bourdeau I, Griffin KJ, Courcoutsakis N, Stergiopoulos S, Batista D, Tsokos M, Stratakis CA. A pleiomorphic GH pituitary adenoma from a Carney complex patient displays universal allelic loss at the protein kinase A regulatory subunit 1A (PRKARIA) locus. J Med Genet. 2004 Aug; 41(8):596-600. PMID: 15286154; PMCID: PMC1735874.
  79. Cassarino DS, Santi M, Arruda A, Patrocinio R, Tsokos M, Ghatak N, Quezado M. Spinal adrenal cortical adenoma with oncocytic features: report of the first intramedullary case and review of the literature. Int J Surg Pathol. 2004 Jul; 12(3):259-64. PMID: 15306940.
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  80. Gunther DF, Bourdeau I, Matyakhina L, Cassarino D, Kleiner DE, Griffin K, Courkoutsakis N, Abu-Asab M, Tsokos M, Keil M, Carney JA, Stratakis CA. Cyclical Cushing syndrome presenting in infancy: an early form of primary pigmented nodular adrenocortical disease, or a new entity? J Clin Endocrinol Metab. 2004 Jul; 89(7):3173-82. PMID: 15240590.
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  81. Stergiopoulos SG, Abu-Asab MS, Tsokos M, Stratakis CA. Pituitary pathology in Carney complex patients. Pituitary. 2004; 7(2):73-82. PMID: 15761655; PMCID: PMC2366887.
  82. Vaurs-Barriere C, Wong K, Weibel TD, Abu-Asab M, Weiss MD, Kaneski CR, Mixon TH, Bonavita S, Creveaux I, Heiss JD, Tsokos M, Goldin E, Quarles RH, Boespflug-Tanguy O, Schiffmann R. Insertion of mutant proteolipid protein results in missorting of myelin proteins. Ann Neurol. 2003 Dec; 54(6):769-80. PMID: 14681886; PMCID: PMC4294275.
  83. Gorlick R, Anderson P, Andrulis I, Arndt C, Beardsley GP, Bernstein M, Bridge J, Cheung NK, Dome JS, Ebb D, Gardner T, Gebhardt M, Grier H, Hansen M, Healey J, Helman L, Hock J, Houghton J, Houghton P, Huvos A, Khanna C, Kieran M, Kleinerman E, Ladanyi M, Lau C, Malkin D, Marina N, Meltzer P, Meyers P, Schofield D, Schwartz C, Smith MA, Toretsky J, Tsokos M, Wexler L, Wigginton J, Withrow S, Schoenfeldt M, Anderson B. Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary. Clin Cancer Res. 2003 Nov 15; 9(15):5442-53. PMID: 14654523.
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  84. Tsokos GC, Tsokos M. The TRAIL to arthritis. J Clin Invest. 2003 Nov; 112(9):1315-7. PMID: 14597758; PMCID: PMC228491.
  85. Debelenko LV, Arthur DC, Pack SD, Helman LJ, Schrump DS, Tsokos M. Identification of CARS-ALK fusion in primary and metastatic lesions of an inflammatory myofibroblastic tumor. Lab Invest. 2003 Sep; 83(9):1255-65. PMID: 13679433.
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  86. Krakowiak PA, Wassif CA, Kratz L, Cozma D, Kovárová M, Harris G, Grinberg A, Yang Y, Hunter AG, Tsokos M, Kelley RI, Porter FD. Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency. Hum Mol Genet. 2003 Jul 01; 12(13):1631-41. PMID: 12812989.
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  87. Uren A, Merchant MS, Sun CJ, Vitolo MI, Sun Y, Tsokos M, Illei PB, Ladanyi M, Passaniti A, Mackall C, Toretsky JA. Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells. Oncogene. 2003 Apr 17; 22(15):2334-42. PMID: 12700668.
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  88. Yang X, Merchant MS, Romero ME, Tsokos M, Wexler LH, Kontny U, Mackall CL, Thiele CJ. Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. Cancer Res. 2003 Mar 01; 63(5):1122-9. PMID: 12615731.
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  89. Li RM, Mannon RB, Kleiner D, Tsokos M, Bynum M, Kirk AD, Kopp JB. BK virus and SV40 co-infection in polyomavirus nephropathy. Transplantation. 2002 Dec 15; 74(11):1497-504. PMID: 12490781.
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  90. Tsokos M, Paulsen F. Expression of pulmonary lactoferrin in sudden-onset and slow-onset asthma with fatal outcome. Virchows Arch. 2002 Nov; 441(5):494-9. PMID: 12447681.
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  91. Wassif CA, Vied D, Tsokos M, Connor WE, Steiner RD, Porter FD. Cholesterol storage defect in RSH/Smith-Lemli-Opitz syndrome fibroblasts. Mol Genet Metab. 2002 Apr; 75(4):325-34. PMID: 12051964.
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  92. Dagher R, Long LM, Read EJ, Leitman SF, Carter CS, Tsokos M, Goletz TJ, Avila N, Berzofsky JA, Helman LJ, Mackall CL. Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: an inter-institute NIH study. Med Pediatr Oncol. 2002 Mar; 38(3):158-64. PMID: 11836714.
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  93. Khanna C, Jaboin JJ, Drakos E, Tsokos M, Thiele CJ. Biologically relevant orthotopic neuroblastoma xenograft models: primary adrenal tumor growth and spontaneous distant metastasis. In Vivo. 2002 Mar-Apr; 16(2):77-85. PMID: 12073775.
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  94. Njoku DB, Shrestha S, Soloway R, Duray PR, Tsokos M, Abu-Asab MS, Pohl LR, West AB. Subcellular localization of trifluoroacetylated liver proteins in association with hepatitis following isoflurane. Anesthesiology. 2002 Mar; 96(3):757-61. PMID: 11873055.
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  95. Tsokos M, Anders S, Paulsen F. Lectin binding patterns of alveolar epithelium and subepithelial seromucous glands of the bronchi in sepsis and controls--an approach to characterize the non-specific immunological response of the human lung to sepsis. Virchows Arch. 2002 Feb; 440(2):181-6. PMID: 11964049.
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  96. Kogulan PK, Smith M, Seidman J, Chang G, Tsokos M, Lucey D. Malakoplakia involving the abdominal wall, urinary bladder, vagina, and vulva: case report and discussion of malakoplakia-associated bacteria. Int J Gynecol Pathol. 2001 Oct; 20(4):403-6. PMID: 11603228.
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  97. Gonzalez CE, Lyman CA, Lee S, Del Guercio C, Roilides E, Bacher J, Gehrt A, Feuerstein E, Tsokos M, Walsh TJ. Recombinant human macrophage colony-stimulating factor augments pulmonary host defences against Aspergillus fumigatus. Cytokine. 2001 Jul 21; 15(2):87-95. PMID: 11500084.
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  98. Poulaki V, Mitsiades N, Romero ME, Tsokos M. Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2. Cancer Res. 2001 Jun 15; 61(12):4864-72. PMID: 11406564.
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  99. Tsokos M, Reichelt U, Jung R, Nierhaus A, Püschel K. Interleukin-6 and C-reactive protein serum levels in sepsis-related fatalities during the early postmortem period. Forensic Sci Int. 2001 Jun 01; 119(1):47-56. PMID: 11348793.
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  100. Leone A, Mitsiades N, Ward Y, Spinelli B, Poulaki V, Tsokos M, Kelly K. The Gem GTP-binding protein promotes morphological differentiation in neuroblastoma. Oncogene. 2001 May 31; 20(25):3217-25. PMID: 11423971.
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  101. Dagher R, Pham TA, Sorbara L, Kumar S, Long L, Bernstein D, Mackall C, Raffeld M, Tsokos M, Helman L. Molecular confirmation of Ewing sarcoma. J Pediatr Hematol Oncol. 2001 May; 23(4):221-4. PMID: 11846300.
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  102. Tsokos M, Anders S, Paulsen F, Fehlauer F, Püschel K. Comparative evaluation of pulmonary lactoferrin and lysozyme immunoreactivity for the postmortem diagnosis of death due to sepsis. Virchows Arch. 2001 Apr; 438(4):376-81. PMID: 11355172.
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  103. Gaertner EM, Tsokos M, Derringer GA, Neuhauser TS, Arciero C, Andriko JA. Interdigitating dendritic cell sarcoma. A report of four cases and review of the literature. Am J Clin Pathol. 2001 Apr; 115(4):589-97. PMID: 11293908.
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  104. Mitsiades N, Poulaki V, Mitsiades C, Tsokos M. Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5. Cancer Res. 2001 Mar 15; 61(6):2704-12. PMID: 11289151.
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  105. LaVaute T, Smith S, Cooperman S, Iwai K, Land W, Meyron-Holtz E, Drake SK, Miller G, Abu-Asab M, Tsokos M, Switzer R, Grinberg A, Love P, Tresser N, Rouault TA. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet. 2001 Feb; 27(2):209-14. PMID: 11175792.
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  106. Cope JU, Tsokos M, Miller RW. Ewing sarcoma and sinonasal neuroectodermal tumors as second malignant tumors after retinoblastoma and other neoplasms. Med Pediatr Oncol. 2001 Feb; 36(2):290-4. PMID: 11452937.
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  107. Mitsiades N, Yu WH, Poulaki V, Tsokos M, Stamenkovic I. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer Res. 2001 Jan 15; 61(2):577-81. PMID: 11212252.
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  108. Tsokos M, Reichelt U, Nierhaus A, Püschel K. Serum procalcitonin (PCT): a valuable biochemical parameter for the post-mortem diagnosis of sepsis. Int J Legal Med. 2001; 114(4-5):237-43. PMID: 11355402.
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  109. Kim JS, Pirnia F, Choi YH, Nguyen PM, Knepper B, Tsokos M, Schulte TW, Birrer MJ, Blagosklonny MV, Schaefer O, Mushinski JF, Trepel JB. Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint. Oncogene. 2000 Dec 07; 19(52):6082-90. PMID: 11146561.
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  110. Hewitt RE, McMarlin A, Kleiner D, Wersto R, Martin P, Tsokos M, Stamp GW, Stetler-Stevenson WG, Tsoskas M. Validation of a model of colon cancer progression. J Pathol. 2000 Dec; 192(4):446-54. PMID: 11113861.
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  111. Kumar S, Perlman E, Harris CA, Raffeld M, Tsokos M. Myogenin is a specific marker for rhabdomyosarcoma: an immunohistochemical study in paraffin-embedded tissues. Mod Pathol. 2000 Sep; 13(9):988-93. PMID: 11007039.
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  112. Caffrey M, Braddock DT, Louis JM, Abu-Asab MA, Kingma D, Liotta L, Tsokos M, Tresser N, Pannell LK, Watts N, Steven AC, Simon MN, Stahl SJ, Wingfield PT, Clore GM. Biophysical characterization of gp41 aggregates suggests a model for the molecular mechanism of HIV-associated neurological damage and dementia. J Biol Chem. 2000 Jun 30; 275(26):19877-82. PMID: 10747981.
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  113. Wexler LH, Meyer WH, Parham DM, Tsokos M. Neural differentiation and prognosis in peripheral primitive neuroectodermal tumor. J Clin Oncol. 2000 May; 18(10):2187-8. PMID: 10811686.
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  114. Bornstein SR, Abu-Asab M, Glasow A, Päth G, Hauner H, Tsokos M, Chrousos GP, Scherbaum WA. Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture. Diabetes. 2000 Apr; 49(4):532-8. PMID: 10871189.
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  115. Cope JU, Tsokos M, Helman LJ, Gridley G, Tucker MA. Inguinal hernia in patients with Ewing sarcoma: a clue to etiology. Med Pediatr Oncol. 2000 Mar; 34(3):195-9. PMID: 10696126.
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  116. Kruger EA, Duray PH, Tsokos MG, Venzon DJ, Libutti SK, Dixon SC, Rudek MA, Pluda J, Allegra C, Figg WD. Endostatin inhibits microvessel formation in the ex vivo rat aortic ring angiogenesis assay. Biochem Biophys Res Commun. 2000 Feb 05; 268(1):183-91. PMID: 10652234.
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  117. Orban Z, Mitsiades N, Burke TR, Tsokos M, Chrousos GP. Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation. Neuroimmunomodulation. 2000; 7(2):99-105. PMID: 10686520.
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  118. Khanna C, Prehn J, Yeung C, Caylor J, Tsokos M, Helman L. An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential. Clin Exp Metastasis. 2000; 18(3):261-71. PMID: 11315100.
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  119. Lubensky IA, Schiffmann R, Goldin E, Tsokos M. Lysosomal inclusions in gastric parietal cells in mucolipidosis type IV: a novel cause of achlorhydria and hypergastrinemia. Am J Surg Pathol. 1999 Dec; 23(12):1527-31. PMID: 10584706.
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  120. Kumar S, Perlman E, Pack S, Davis M, Zhang H, Meltzer P, Tsokos M. Absence of EWS/FLI1 fusion in olfactory neuroblastomas indicates these tumors do not belong to the Ewing's sarcoma family. Hum Pathol. 1999 Nov; 30(11):1356-60. PMID: 10571517.
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  121. Mitsiades N, Poulaki V, Leone A, Tsokos M. Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors. J Natl Cancer Inst. 1999 Oct 06; 91(19):1678-84. PMID: 10511596.
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  122. Koski GK, Schwartz GN, Weng DE, Gress RE, Engels FH, Tsokos M, Czerniecki BJ, Cohen PA. Calcium ionophore-treated myeloid cells acquire many dendritic cell characteristics independent of prior differentiation state, transformation status, or sensitivity to biologic agents. Blood. 1999 Aug 15; 94(4):1359-71. PMID: 10438724.
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  123. Parham DM, Hijazi Y, Steinberg SM, Meyer WH, Horowitz M, Tzen CY, Wexler LH, Tsokos M. Neuroectodermal differentiation in Ewing's sarcoma family of tumors does not predict tumor behavior. Hum Pathol. 1999 Aug; 30(8):911-8. PMID: 10452503.
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  124. Mitsiades N, Poulaki V, Mastorakos G, Tseleni-Balafouta ST, Kotoula V, Koutras DA, Tsokos M. Fas ligand expression in thyroid carcinomas: a potential mechanism of immune evasion. J Clin Endocrinol Metab. 1999 Aug; 84(8):2924-32. PMID: 10443700.
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  125. Bar-Ner M, Thibault A, Tsokos M, Magrath IT, Samid D. Phenylbutyrate induces cell differentiation and modulates Epstein-Barr virus gene expression in Burkitt's lymphoma cells. Clin Cancer Res. 1999 Jun; 5(6):1509-16. PMID: 10389940.
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  126. Kouraklis G, Triche TJ, Wesley R, Tsokos M. Myc oncogene expression and nude mouse tumorigenicity and metastasis formation are higher in alveolar than embryonal rhabdomyosarcoma cell lines. Pediatr Res. 1999 Apr; 45(4 Pt 1):552-8. PMID: 10203148.
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  127. Kumar S, Pack S, Kumar D, Walker R, Quezado M, Zhuang Z, Meltzer P, Tsokos M. Detection of EWS-FLI-1 fusion in Ewing's sarcoma/peripheral primitive neuroectodermal tumor by fluorescence in situ hybridization using formalin-fixed paraffin-embedded tissue. Hum Pathol. 1999 Mar; 30(3):324-30. PMID: 10088552.
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  128. Samuel DP, Tsokos M, DeBaun MR. Hemihypertrophy and a poorly differentiated embryonal rhabdomyosarcoma of the pelvis. Med Pediatr Oncol. 1999 Jan; 32(1):38-43. PMID: 9917751.
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  129. Püschel K, Schulz F, Darrmann I, Tsokos M. Macromorphology and histology of intramuscular hemorrhages in cases of drowning. Int J Legal Med. 1999; 112(2):101-6. PMID: 10048667.
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  130. Fidelia-Lambert MN, Zhuang Z, Tsokos M. Sensitive detection of rare Ewing's sarcoma cells in peripheral blood by reverse transcriptase polymerase chain reaction. Hum Pathol. 1999 Jan; 30(1):78-80. PMID: 9923931.
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  131. Mitsiades N, Poulaki V, Kotoula V, Leone A, Tsokos M. Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase. Am J Pathol. 1998 Dec; 153(6):1947-56. PMID: 9846984; PMCID: PMC1866328.
  132. Weil RJ, Huang S, Pack S, Vortmeyer AO, Tsokos M, Lubensky IA, Oldfield EH, Zhuang Z. Pluripotent tumor cells in benign pituitary adenomas associated with multiple endocrine neoplasia type 1. Cancer Res. 1998 Oct 15; 58(20):4715-20. PMID: 9788627.
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  133. Andriko JW, Kaldjian EP, Tsokos M, Abbondanzo SL, Jaffe ES. Reticulum cell neoplasms of lymph nodes: a clinicopathologic study of 11 cases with recognition of a new subtype derived from fibroblastic reticular cells. Am J Surg Pathol. 1998 Sep; 22(9):1048-58. PMID: 9737236.
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  134. Butler AA, Blakesley VA, Poulaki V, Tsokos M, Wood TL, LeRoith D, Pouliki V. Stimulation of tumor growth by recombinant human insulin-like growth factor-I (IGF-I) is dependent on the dose and the level of IGF-I receptor expression. Cancer Res. 1998 Jul 15; 58(14):3021-7. PMID: 9679966.
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  135. Mitsiades N, Poulaki V, Kotoula V, Mastorakos G, Tseleni-Balafouta S, Koutras DA, Tsokos M. Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis. J Clin Endocrinol Metab. 1998 Jun; 83(6):2199-203. PMID: 9626160.
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  136. Bornstein SR, Webster EL, Torpy DJ, Richman SJ, Mitsiades N, Igel M, Lewis DB, Rice KC, Joost HG, Tsokos M, Chrousos GP. Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation. Endocrinology. 1998 Apr; 139(4):1546-55. PMID: 9528933.
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  137. Schiffmann R, Dwyer NK, Lubensky IA, Tsokos M, Sutliff VE, Latimer JS, Frei KP, Brady RO, Barton NW, Blanchette-Mackie EJ, Goldin E. Constitutive achlorhydria in mucolipidosis type IV. Proc Natl Acad Sci U S A. 1998 Feb 03; 95(3):1207-12. PMID: 9448310; PMCID: PMC18720.
  138. Quezado M, Benjamin DR, Tsokos M. EWS/FLI-1 fusion transcripts in three peripheral primitive neuroectodermal tumors of the kidney. Hum Pathol. 1997 Jul; 28(7):767-71. PMID: 9224742.
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  139. Beckner ME, Krutzsch HC, Tsokos M, Moul DE, Liotta LA. The aggregated form of an AAMP derived peptide behaves as a heparin sensitive cell binding agent. Biotechnol Bioeng. 1997 May 20; 54(4):365-72. PMID: 18634104.
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  140. Katz RL, Quezado M, Senderowicz AM, Villalba L, Laskin WB, Tsokos M. An intra-abdominal small round cell neoplasm with features of primitive neuroectodermal and desmoplastic round cell tumor and a EWS/FLI-1 fusion transcript. Hum Pathol. 1997 Apr; 28(4):502-9. PMID: 9104953.
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  141. Kleiner DE, Gaffey MJ, Sallie R, Tsokos M, Nichols L, McKenzie R, Straus SE, Hoofnagle JH. Histopathologic changes associated with fialuridine hepatotoxicity. Mod Pathol. 1997 Mar; 10(3):192-9. PMID: 9071726.
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  142. Kingma DW, Shad A, Tsokos M, Fest T, Otsuki T, Frekko K, Werner E, Werner A, Magrath I, Raffeld M, Jaffe ES. Epstein-Barr virus (EBV)-associated smooth-muscle tumor arising in a post-transplant patient treated successfully for two PT-EBV-associated large-cell lymphomas. Case report. Am J Surg Pathol. 1996 Dec; 20(12):1511-9. PMID: 8944045.
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  143. Hill SC, Damaska BM, Tsokos M, Kreps C, Brady RO, Barton NW. Radiographic findings in type 3b Gaucher disease. Pediatr Radiol. 1996 Dec; 26(12):852-60. PMID: 8929296.
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  144. Kalebic T, Tsokos M, Helman LJ. Suppression of rhabdomyosarcoma growth by fumagillin analog TNP-470. Int J Cancer. 1996 Nov 27; 68(5):596-9. PMID: 8938140.
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  145. Wexler LH, DeLaney TF, Tsokos M, Avila N, Steinberg SM, Weaver-McClure L, Jacobson J, Jarosinski P, Hijazi YM, Balis FM, Horowitz ME. Ifosfamide and etoposide plus vincristine, doxorubicin, and cyclophosphamide for newly diagnosed Ewing's sarcoma family of tumors. Cancer. 1996 Aug 15; 78(4):901-11. PMID: 8756388.
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  146. Keleti J, Quezado MM, Abaza MM, Raffeld M, Tsokos M. The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein. Am J Pathol. 1996 Jul; 149(1):143-51. PMID: 8686737; PMCID: PMC1865219.
  147. Wu AJ, Chen ZJ, Tsokos M, O'Connell BC, Ambudkar IS, Baum BJ. Interferon-gamma induced cell death in a cultured human salivary gland cell line. J Cell Physiol. 1996 May; 167(2):297-304. PMID: 8613471.
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  148. Cavazza A, Colby TV, Tsokos M, Rush W, Travis WD. Lung tumors with a rhabdoid phenotype. Am J Clin Pathol. 1996 Feb; 105(2):182-8. PMID: 8607442.
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  149. Pacelli R, Wink DA, Cook JA, Krishna MC, DeGraff W, Friedman N, Tsokos M, Samuni A, Mitchell JB. Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli. J Exp Med. 1995 Nov 01; 182(5):1469-79. PMID: 7595217; PMCID: PMC2192188.
  150. McKenzie R, Fried MW, Sallie R, Conjeevaram H, Di Bisceglie AM, Park Y, Savarese B, Kleiner D, Tsokos M, Luciano C, et al. Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med. 1995 Oct 26; 333(17):1099-105. PMID: 7565947.
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  151. He CJ, Striker LJ, Tsokos M, Yang CW, Peten EP, Striker GE. Relationships between mesangial cell proliferation and types I and IV collagen mRNA levels in vitro. Am J Physiol. 1995 Sep; 269(3 Pt 1):C554-62. PMID: 7573384.
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  152. Scala S, Budillon A, Zhan Z, Cho-Chung YS, Jefferson J, Tsokos M, Bates SE. Downregulation of mdr-1 expression by 8-Cl-cAMP in multidrug resistant MCF-7 human breast cancer cells. J Clin Invest. 1995 Aug; 96(2):1026-34. PMID: 7543490; PMCID: PMC286382.
  153. Pass HI, Stevens EJ, Oie H, Tsokos MG, Abati AD, Fetsch PA, Mew DJ, Pogrebniak HW, Matthews WJ. Characteristics of nine newly derived mesothelioma cell lines. Ann Thorac Surg. 1995 Apr; 59(4):835-44. PMID: 7695406.
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  154. Pavlidis NA, Klouvas G, Tsokos M, Bai M, Moutsopoulos HM. Cutaneous lymphocytic vasculopathy in lymphoproliferative disorders--a paraneoplastic lymphocytic vasculitis of the skin. Leuk Lymphoma. 1995 Feb; 16(5-6):477-82. PMID: 7787755.
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  155. Emmert-Buck MR, Stay EJ, Tsokos M, Travis WD. Pleomorphic rhabdomyosarcoma arising in association with the right pulmonary artery. Arch Pathol Lab Med. 1994 Dec; 118(12):1220-2. PMID: 7979918.
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  156. Asmar L, Gehan EA, Newton WA, Webber BL, Marsden HB, van Unnik AJ, Hamoudi AB, Shimada H, Tsokos M, Harms D, et al. Agreement among and within groups of pathologists in the classification of rhabdomyosarcoma and related childhood sarcomas. Report of an international study of four pathology classifications. Cancer. 1994 Nov 01; 74(9):2579-88. PMID: 7923014.
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  157. Kalebic T, Tsokos M, Helman LJ. In vivo treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34cdc2. Cancer Res. 1994 Nov 01; 54(21):5531-4. PMID: 7923191.
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  158. Hijazi YM, Axiotis CA, Navarro S, Steinberg SM, Horowitz ME, Tsokos M. Immunohistochemical detection of P-glycoprotein in Ewing's sarcoma and peripheral primitive neuroectodermal tumors before and after chemotherapy. Am J Clin Pathol. 1994 Jul; 102(1):61-7. PMID: 7913576.
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  159. Bang YJ, Pirnia F, Fang WG, Kang WK, Sartor O, Whitesell L, Ha MJ, Tsokos M, Sheahan MD, Nguyen P, Niklinski WT, Myers CE, Trepel JB. Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5330-4. PMID: 8202489; PMCID: PMC43988.
  160. Minniti CP, Tsokos M, Newton WA, Helman LJ. Specific expression of insulin-like growth factor-II in rhabdomyosarcoma tumor cells. Am J Clin Pathol. 1994 Feb; 101(2):198-203. PMID: 8116575.
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  161. Tsokos M. The diagnosis and classification of childhood rhabdomyosarcoma. Semin Diagn Pathol. 1994 Feb; 11(1):26-38. PMID: 8202644.
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  162. Roth MJ, Medeiros LJ, Kapur S, Wexler LH, Mims S, Horowitz ME, Tsokos M. Malignant schwannoma with melanocytic and neuroepithelial differentiation in an infant with congenital giant melanocytic nevus: a complex neurocristopathy. Hum Pathol. 1993 Dec; 24(12):1371-5. PMID: 8276386.
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  163. Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules. J Exp Med. 1993 Nov 01; 178(5):1701-12. PMID: 8228817; PMCID: PMC2191226.
  164. Horowitz ME, Kinsella TJ, Wexler LH, Belasco J, Triche T, Tsokos M, Steinberg SM, McClure L, Longo DL, Steis RG, et al. Total-body irradiation and autologous bone marrow transplant in the treatment of high-risk Ewing's sarcoma and rhabdomyosarcoma. J Clin Oncol. 1993 Oct; 11(10):1911-8. PMID: 8410118.
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  165. Bock GH, Long CA, Riley ML, White JD, Kurman CC, Fleisher TA, Tsokos M, Brown M, Serbousek D, Schwietermann WD, et al. Characterization of a new IL-6-dependent human B-lymphoma cell line in long term culture. Cytokine. 1993 Sep; 5(5):480-9. PMID: 8142604.
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  166. Navarro S, Pellín A, Noguera R, Díaz MP, Tsokos M, Triche TJ, Llombart-Bosch A. dbl oncogene expression in childhood tumors and tumor cell lines. Diagn Mol Pathol. 1993 Sep; 2(3):158-62. PMID: 8287229.
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  167. Felix CA, Strauss EA, D'Amico D, Tsokos M, Winter S, Mitsudomi T, Nau MM, Brown DL, Leahey AM, Horowitz ME, et al. A novel germline p53 splicing mutation in a pediatric patient with a second malignant neoplasm. Oncogene. 1993 May; 8(5):1203-10. PMID: 8479743.
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  168. Herzog CE, Tsokos M, Bates SE, Fojo AT. Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists. J Biol Chem. 1993 Feb 05; 268(4):2946-52. PMID: 8094079.
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  169. Crouch GD, Kalebic T, Tsokos M, Helman LJ. Ara-C treatment leads to differentiation and reverses the transformed phenotype in a human rhabdomyosarcoma cell line. Exp Cell Res. 1993 Feb; 204(2):210-6. PMID: 8440318.
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  170. McCune BK, Patterson K, Chandra RS, Kapur S, Sporn MB, Tsokos M. Expression of transforming growth factor-beta isoforms in small round cell tumors of childhood. An immunohistochemical study. Am J Pathol. 1993 Jan; 142(1):49-58. PMID: 8380955; PMCID: PMC1886834.
  171. MacLeod CB, Repetti CF, Tsokos M. Enzymatic treatments on paraffin blocks for DNA flow cytometry. Mod Pathol. 1992 Sep; 5(5):569-74. PMID: 1344822.
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  172. Filling-Katz MR, Miller SP, Merrick HF, Travis WD, Gregg RE, Tsokos M, Comly M, Kaneski CR, Mackie S, Lebovics RS, et al. Clinical, pathologic, and biochemical features of a cholesterol lipidosis accompanied by hyperlipidemia and xanthomas. Neurology. 1992 Sep; 42(9):1768-74. PMID: 1513468.
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  173. Horowitz ME, Tsokos MG, DeLaney TF. Ewing's sarcoma. CA Cancer J Clin. 1992 Sep-Oct; 42(5):300-20. PMID: 1515969.
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  174. Tsokos M, Webber BL, Parham DM, Wesley RA, Miser A, Miser JS, Etcubanas E, Kinsella T, Grayson J, Glatstein E, et al. Rhabdomyosarcoma. A new classification scheme related to prognosis. Arch Pathol Lab Med. 1992 Aug; 116(8):847-55. PMID: 1497467.
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  175. Felix CA, Kappel CC, Mitsudomi T, Nau MM, Tsokos M, Crouch GD, Nisen PD, Winick NJ, Helman LJ. Frequency and diversity of p53 mutations in childhood rhabdomyosarcoma. Cancer Res. 1992 Apr 15; 52(8):2243-7. PMID: 1559227.
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  176. Noguera R, Triche TJ, Navarro S, Tsokos M, Llombart-Bosch A. Dynamic model of differentiation in Ewing's sarcoma cells. Comparative analysis of morphologic, immunocytochemical, and oncogene expression parameters. Lab Invest. 1992 Feb; 66(2):143-51. PMID: 1310513.
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  177. Tsokos M. Peripheral primitive neuroectodermal tumors. Diagnosis, classification, and prognosis. Perspect Pediatr Pathol. 1992; 16:27-98. PMID: 1335143.
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  178. Hoffman GS, Filie JD, Schumacher HR, Ortiz-Bravo E, Tsokos MG, Marini JC, Kerr GS, Ling QH, Trentham DE. Intractable vasculitis, resorptive osteolysis, and immunity to type I collagen in type VIII Ehlers-Danlos syndrome. Arthritis Rheum. 1991 Nov; 34(11):1466-75. PMID: 1953824.
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  179. Bates SE, Shieh CY, Tsokos M. Expression of mdr-1/P-glycoprotein in human neuroblastoma. Am J Pathol. 1991 Aug; 139(2):305-15. PMID: 1678252; PMCID: PMC1886082.
  180. Travis WD, Linnoila RI, Tsokos MG, Hitchcock CL, Cutler GB, Nieman L, Chrousos G, Pass H, Doppman J. Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases. Am J Surg Pathol. 1991 Jun; 15(6):529-53. PMID: 1709558.
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  181. MacLeod CB, Tsokos M. Gastrointestinal autonomic nerve tumor. Ultrastruct Pathol. 1991 Jan-Feb; 15(1):49-55. PMID: 1849328.
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  182. Travis WD, Lack EE, Azumi N, Tsokos M, Norton J. Adenomatoid tumor of the adrenal gland with ultrastructural and immunohistochemical demonstration of a mesothelial origin. Arch Pathol Lab Med. 1990 Jul; 114(7):722-4. PMID: 2194445.
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  183. Murphy LD, Valverius EM, Tsokos M, Mickley LA, Rosen N, Bates SE. Modulation of EGF receptor expression by differentiating agents in human colon carcinoma cell lines. Cancer Commun. 1990; 2(10):345-55. PMID: 2206777.
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  184. Bader JL, Horowitz ME, Dewan R, Watkins E, Triche TJ, Tsokos M, Kinsella TJ, Miser JS, Steinberg SM, Glatstein E. Intensive combined modality therapy of small round cell and undifferentiated sarcomas in children and young adults: local control and patterns of failure. Radiother Oncol. 1989 Nov; 16(3):189-201. PMID: 2587810.
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  185. Travis WD, Tsokos M, Doppman JL, Nieman L, Chrousos GP, Cutler GB, Loriaux DL, Norton JA. Primary pigmented nodular adrenocortical disease. A light and electron microscopic study of eight cases. Am J Surg Pathol. 1989 Nov; 13(11):921-30. PMID: 2679153.
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  186. Travis WD, Davis GE, Tsokos M, Lebovics R, Merrick HF, Miller SP, Gregg RE, Di Bisceglie AM, Parker RI, Ishak KG, et al. Multifocal verruciform xanthoma of the upper aerodigestive tract in a child with a systemic lipid storage disease. Am J Surg Pathol. 1989 Apr; 13(4):309-16. PMID: 2539022.
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  187. Tsokos M, Kouraklis G, Chandra RS, Bhagavan BS, Triche TJ. Malignant rhabdoid tumor of the kidney and soft tissues. Evidence for a diverse morphological and immunocytochemical phenotype. Arch Pathol Lab Med. 1989 Feb; 113(2):115-20. PMID: 2916902.
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  188. Miser JS, Kinsella TJ, Triche TJ, Tsokos M, Forquer R, Wesley R, Horvath K, Belasco J, Longo DL, Steis R, et al. Preliminary results of treatment of Ewing's sarcoma of bone in children and young adults: six months of intensive combined modality therapy without maintenance. J Clin Oncol. 1988 Mar; 6(3):484-90. PMID: 3280743.
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  189. Miser JS, Kinsella TJ, Triche TJ, Steis R, Tsokos M, Wesley R, Horvath K, Belasco J, Longo DL, Glatstein E, et al. Treatment of peripheral neuroepithelioma in children and young adults. J Clin Oncol. 1987 Nov; 5(11):1752-8. PMID: 3316513.
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  190. Tsokos M, Scarpa S, Ross RA, Triche TJ. Differentiation of human neuroblastoma recapitulates neural crest development. Study of morphology, neurotransmitter enzymes, and extracellular matrix proteins. Am J Pathol. 1987 Sep; 128(3):484-96. PMID: 2888312; PMCID: PMC1899665.
  191. Miser JS, Kinsella TJ, Triche TJ, Tsokos M, Jarosinski P, Forquer R, Wesley R, Magrath I. Ifosfamide with mesna uroprotection and etoposide: an effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults. J Clin Oncol. 1987 Aug; 5(8):1191-8. PMID: 3114435.
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  192. Tsokos M, Kyritsis AP, Chader GJ, Triche TJ. Differentiation of human retinoblastoma in vitro into cell types with characteristics observed in embryonal or mature retina. Am J Pathol. 1986 Jun; 123(3):542-52. PMID: 3013012; PMCID: PMC1888264.
  193. Linnoila RI, Tsokos M, Triche TJ, Marangos PJ, Chandra RS. Evidence for neural origin and PAS-positive variants of the malignant small cell tumor of thoracopulmonary region ("Askin tumor"). Am J Surg Pathol. 1986 Feb; 10(2):124-33. PMID: 3953935.
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  194. Malone DG, Wahl SM, Tsokos M, Cattell H, Decker JL, Wilder RL. Immune function in severe, active rheumatoid arthritis. A relationship between peripheral blood mononuclear cell proliferation to soluble antigens and synovial tissue immunohistologic characteristics. J Clin Invest. 1984 Oct; 74(4):1173-85. PMID: 6384266; PMCID: PMC425283.
  195. Tsokos M, Linnoila RI, Chandra RS, Triche TJ. Neuron-specific enolase in the diagnosis of neuroblastoma and other small, round-cell tumors in children. Hum Pathol. 1984 Jun; 15(6):575-84. PMID: 6373565.
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  196. Jaffe ES, Costa J, Fauci AS, Cossman J, Tsokos M. Malignant lymphoma and erythrophagocytosis simulating malignant histiocytosis. Am J Med. 1983 Nov; 75(5):741-9. PMID: 6638043.
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  197. Tsokos M, Howard R, Costa J. Immunohistochemical study of alveolar and embryonal rhabdomyosarcoma. Lab Invest. 1983 Feb; 48(2):148-55. PMID: 6337300.
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