Harvard Catalyst Profiles

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Maria Tsokos, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Pan W, Sharabi A, Ferretti A, Zhang Y, Burbano C, Yoshida N, Tsokos MG, Tsokos GC. PPP2R2D suppresses IL-2 production and Treg function. JCI Insight. 2020 Oct 02; 5(19). PMID: 32897879.
    Citations:    Fields:    
  2. Bhargava R, Maeda K, Tsokos MG, Pavlakis M, Stillman IE, Tsokos GC. N-glycosylated IgG in patients with kidney transplants increases calcium/calmodulin kinase IV in podocytes and causes injury. Am J Transplant. 2020 Jun 12. PMID: 32531122.
    Citations:    Fields:    
  3. Li H, Adamopoulos IE, Moulton VR, Stillman IE, Herbert Z, Moon JJ, Sharabi A, Krishfield S, Tsokos MG, Tsokos GC. Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells. Nat Commun. 2020 06 05; 11(1):2859. PMID: 32503973.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Meidan E, Li H, Pan W, Kono M, Yu S, Kyttaris VC, Ioannidis C, Rodriguez Rodriguez N, Crispin JC, Apostolidis SA, Lee P, Manis J, Sharabi A, Tsokos MG, Tsokos GC. Serine/threonine phosphatase PP2A is essential for optimal B cell function. JCI Insight. 2020 03 12; 5(5). PMID: 32161189.
    Citations: 1     Fields:    
  5. Satyam A, Andreo K, Lapchak PH, Dalle Lucca JJ, Davis RB, Tsokos MG, Shapiro NI, Tsokos GC. Complement Deposition on the Surface of RBC After Trauma Serves a Biomarker of Moderate Trauma Severity: A Prospective Study. Shock. 2020 01; 53(1):16-23. PMID: 30998651.
    Citations: 2     Fields:    
  6. Suarez-Fueyo A, Tsokos MG, Kwok SK, Maeda K, Katsuyama E, Lapchak PH, Tsokos GC. Hyaluronic Acid Synthesis Contributes to Tissue Damage in Systemic Lupus Erythematosus. Front Immunol. 2019; 10:2172. PMID: 31572382.
    Citations:    Fields:    
  7. Kono M, Maeda K, Stocton-Gavanescu I, Pan W, Umeda M, Katsuyama E, Burbano C, Orite SYK, Vukelic M, Tsokos MG, Yoshida N, Tsokos GC. Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation. JCI Insight. 2019 06 20; 4(12). PMID: 31217348.
    Citations: 5     Fields:    Translation:AnimalsCells
  8. Satyam A, Graef ER, Lapchak PH, Tsokos MG, Dalle Lucca JJ, Tsokos GC. Complement and coagulation cascades in trauma. Acute Med Surg. 2019 Oct; 6(4):329-335. PMID: 31592318.
    Citations: 2     
  9. Sharabi A, Li H, Kasper IR, Pan W, Meidan E, Tsokos MG, Moulton VR, Tsokos GC. PP2A enables IL-2 signaling by preserving IL-2Rß chain expression during Treg development. JCI Insight. 2019 03 26; 5. PMID: 30912768.
    Citations: 2     Fields:    Translation:AnimalsCells
  10. Tsokos GC, Tsokos MG. TARGETING TARGETED TREATMENT FOR IMMUNE AND NON-IMMUNE KIDNEY DISEASES. Trans Am Clin Climatol Assoc. 2019; 130:88-99. PMID: 31516171.
    Citations:    Fields:    Translation:HumansAnimalsCells
  11. Manoli I, Sysol JR, Epping MW, Li L, Wang C, Sloan JL, Pass A, Gagné J, Ktena YP, Li L, Trivedi NS, Ouattara B, Zerfas PM, Hoffmann V, Abu-Asab M, Tsokos MG, Kleiner DE, Garone C, Cusmano-Ozog K, Enns GM, Vernon HJ, Andersson HC, Grunewald S, Elkahloun AG, Girard CL, Schnermann J, DiMauro S, Andres-Mateos E, Vandenberghe LH, Chandler RJ, Venditti CP. FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia. JCI Insight. 2018 12 06; 3(23). PMID: 30518688.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  12. Sharabi A, Tsokos MG, Ding Y, Malek TR, Klatzmann D, Tsokos GC. Regulatory T cells in the treatment of disease. Nat Rev Drug Discov. 2018 11; 17(11):823-844. PMID: 30310234.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  13. Ferretti AP, Bhargava R, Dahan S, Tsokos MG, Tsokos GC. Calcium/Calmodulin Kinase IV Controls the Function of Both T Cells and Kidney Resident Cells. Front Immunol. 2018; 9:2113. PMID: 30333818.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  14. Kono M, Yoshida N, Maeda K, Skinner NE, Pan W, Kyttaris VC, Tsokos MG, Tsokos GC. Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):9288-9293. PMID: 30150402.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  15. Li H, Tsokos MG, Bickerton S, Sharabi A, Li Y, Moulton VR, Kong P, Fahmy TM, Tsokos GC. Precision DNA demethylation ameliorates disease in lupus-prone mice. JCI Insight. 2018 08 23; 3(16). PMID: 30135300.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  16. Maeda K, Otomo K, Yoshida N, Abu-Asab MS, Ichinose K, Nishino T, Kono M, Ferretti A, Bhargava R, Maruyama S, Bickerton S, Fahmy TM, Tsokos MG, Tsokos GC. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. J Clin Invest. 2018 08 01; 128(8):3445-3459. PMID: 29985166.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  17. Ahmed AA, Habeebu SS, Sherman AK, Ye SQ, Wood N, Chastain KM, Tsokos MG. Potential Value of YAP Staining in Rhabdomyosarcoma. J Histochem Cytochem. 2018 08; 66(8):577-584. PMID: 29596030.
    Citations:    Fields:    Translation:HumansCells
  18. Geha M, Tsokos MG, Bosse RE, Sannikova T, Iwakura Y, Dalle Lucca JJ, De Waal Malefyt R, Tsokos GC. IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion Injury. J Immunol. 2017 10 15; 199(8):2921-2929. PMID: 28877988.
    Citations:    Fields:    Translation:HumansAnimalsCells
  19. Matsumoto N, Satyam A, Geha M, Lapchak PH, Dalle Lucca JJ, Tsokos MG, Tsokos GC. C3a Enhances the Formation of Intestinal Organoids through C3aR1. Front Immunol. 2017; 8:1046. PMID: 28928734.
    Citations: 2     Fields:    
  20. Corominas H, Tsokos M, Quezado M, Tsokos GC. Aneurysm of the ascending aorta in systemic lupus erythematosus: Case report and review of the literature. Eur J Rheumatol. 2017 Jun; 4(2):133-135. PMID: 28638687.
    Citations: 2     
  21. Satyam A, Kannan L, Matsumoto N, Geha M, Lapchak PH, Bosse R, Shi GP, Dalle Lucca JJ, Tsokos MG, Tsokos GC. Intracellular Activation of Complement 3 Is Responsible for Intestinal Tissue Damage during Mesenteric Ischemia. J Immunol. 2017 01 15; 198(2):788-797. PMID: 27913632.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  22. Long AH, Highfill SL, Cui Y, Smith JP, Walker AJ, Ramakrishna S, El-Etriby R, Galli S, Tsokos MG, Orentas RJ, Mackall CL. Reduction of MDSCs with All-trans Retinoic Acid Improves CAR Therapy Efficacy for Sarcomas. Cancer Immunol Res. 2016 10; 4(10):869-880. PMID: 27549124.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  23. Apostolidis SA, Rodríguez-Rodríguez N, Suárez-Fueyo A, Dioufa N, Ozcan E, Crispín JC, Tsokos MG, Tsokos GC. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016 May; 17(5):556-64. PMID: 26974206.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  24. Marchegiani S, Davis T, Tessadori F, van Haaften G, Brancati F, Hoischen A, Huang H, Valkanas E, Pusey B, Schanze D, Venselaar H, Vulto-van Silfhout AT, Wolfe LA, Tifft CJ, Zerfas PM, Zambruno G, Kariminejad A, Sabbagh-Kermani F, Lee J, Tsokos MG, Lee CC, Ferraz V, da Silva EM, Stevens CA, Roche N, Bartsch O, Farndon P, Bermejo-Sanchez E, Brooks BP, Maduro V, Dallapiccola B, Ramos FJ, Chung HY, Le Caignec C, Martins F, Jacyk WK, Mazzanti L, Brunner HG, Bakkers J, Lin S, Malicdan MC, Boerkoel CF, Gahl WA, de Vries BB, van Haelst MM, Zenker M, Markello TC. Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes. Am J Hum Genet. 2015 Jul 02; 97(1):99-110. PMID: 26119818.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  25. Kalra N, Zhang J, Thomas A, Xi L, Cheung M, Talarchek J, Burkett S, Tsokos MG, Chen Y, Raffeld M, Miettinen M, Pastan I, Testa JR, Hassan R. Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma. BMC Cancer. 2015 May 08; 15:376. PMID: 25952750.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  26. Szarek E, Ball ER, Imperiale A, Tsokos M, Faucz FR, Giubellino A, Moussallieh FM, Namer IJ, Abu-Asab MS, Pacak K, Taïeb D, Carney JA, Stratakis CA. Carney triad, SDH-deficient tumors, and Sdhb+/- mice share abnormal mitochondria. Endocr Relat Cancer. 2015 Jun; 22(3):345-52. PMID: 25808178.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  27. Kahn J, Gillespie A, Tsokos M, Ondos J, Dombi E, Camphausen K, Widemann BC, Kaushal A. Radiation therapy in management of sporadic and neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors. Front Oncol. 2014; 4:324. PMID: 25452937.
    Citations: 18     
  28. Muroya T, Kannan L, Ghiran IC, Shevkoplyas SS, Paz Z, Tsokos M, Dalle Lucca JJ, Shapiro NI, Tsokos GC. C4d deposits on the surface of RBCs in trauma patients and interferes with their function. Crit Care Med. 2014 May; 42(5):e364-72. PMID: 24448198.
    Citations: 4     Fields:    Translation:HumansCells
  29. Arnold MA, Ballester LY, Pack SD, Abdullaev Z, Merchant M, Tsokos MG. Primary subcutaneous spindle cell Ewing sarcoma with strong S100 expression and EWSR1-FLI1 fusion: a case report. Pediatr Dev Pathol. 2014 Jul-Aug; 17(4):302-7. PMID: 24735198.
    Citations:    Fields:    Translation:Humans
  30. Alimchandani M, Lara K, Tsokos M, Linehan WM, Merino MJ. Lymphangitic retroperitoneal carcinomatosis occurring from metastatic sarcomatoid chromophobe renal cell carcinoma. Urol Case Rep. 2014 Mar 01; 2(2):39-62. PMID: 24696789.
  31. Hermanns MI, Müller AM, Tsokos M, Kirkpatrick CJ. LPS-induced effects on angiotensin I-converting enzyme expression and shedding in human pulmonary microvascular endothelial cells. In Vitro Cell Dev Biol Anim. 2014 Apr; 50(4):287-95. PMID: 24165975.
    Citations: 3     Fields:    Translation:HumansCells
  32. Manoli I, Sysol JR, Li L, Houillier P, Garone C, Wang C, Zerfas PM, Cusmano-Ozog K, Young S, Trivedi NS, Cheng J, Sloan JL, Chandler RJ, Abu-Asab M, Tsokos M, Elkahloun AG, Rosen S, Enns GM, Berry GT, Hoffmann V, DiMauro S, Schnermann J, Venditti CP. Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13552-7. PMID: 23898205.
    Citations: 22     Fields:    Translation:HumansAnimalsCTClinical Trials
  33. Lai JP, Liu YC, Alimchandani M, Liu Q, Aung PP, Matsuda K, Lee CC, Tsokos M, Hewitt S, Rushing EJ, Tamura D, Levens DL, Digiovanna JJ, Fine HA, Patronas N, Khan SG, Kleiner DE, Oberholtzer JC, Quezado MM, Kraemer KH. The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D). Acta Neuropathol Commun. 2013 May 08; 1:4. PMID: 24252196.
    Citations: 14     Fields:    Translation:HumansCells
  34. Kleber C, Giesecke MT, Tsokos M, Haas NP, Buschmann CT. Trauma-related preventable deaths in Berlin 2010: need to change prehospital management strategies and trauma management education. World J Surg. 2013 May; 37(5):1154-61. PMID: 23430005.
    Citations: 29     Fields:    Translation:Humans
  35. Killian JK, Kim SY, Miettinen M, Smith C, Merino M, Tsokos M, Quezado M, Smith WI, Jahromi MS, Xekouki P, Szarek E, Walker RL, Lasota J, Raffeld M, Klotzle B, Wang Z, Jones L, Zhu Y, Wang Y, Waterfall JJ, O'Sullivan MJ, Bibikova M, Pacak K, Stratakis C, Janeway KA, Schiffman JD, Fan JB, Helman L, Meltzer PS. Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. Cancer Discov. 2013 Jun; 3(6):648-57. PMID: 23550148.
    Citations: 114     Fields:    Translation:HumansCells
  36. Liu Q, Galli S, Srinivasan R, Linehan WM, Tsokos M, Merino MJ. Renal medullary carcinoma: molecular, immunohistochemistry, and morphologic correlation. Am J Surg Pathol. 2013 Mar; 37(3):368-74. PMID: 23348212.
    Citations: 23     Fields:    Translation:HumansCells
  37. Manoli I, Kwan JY, Wang Q, Rushing EJ, Tsokos M, Arai AE, Burch WM, Dispenzieri A, McPherron AC, Gahl WA. Chronic myopathy due to immunoglobulin light chain amyloidosis. Mol Genet Metab. 2013 Apr; 108(4):249-54. PMID: 23465863.
    Citations: 3     Fields:    Translation:HumansCells
  38. Tobin LA, Xie Y, Tsokos M, Chung SI, Merz AA, Arnold MA, Li G, Malech HL, Kwong KF. Pegylated siRNA-loaded calcium phosphate nanoparticle-driven amplification of cancer cell internalization in vivo. Biomaterials. 2013 Apr; 34(12):2980-90. PMID: 23369215.
    Citations: 8     Fields:    Translation:HumansCells
  39. Arnold MA, Arnold CA, Li G, Chae U, El-Etriby R, Lee CC, Tsokos M. A unique pattern of INI1 immunohistochemistry distinguishes synovial sarcoma from its histologic mimics. Hum Pathol. 2013 May; 44(5):881-7. PMID: 23245672.
    Citations: 8     Fields:    Translation:Humans
  40. Martin-Manso G, Navarathna DH, Galli S, Soto-Pantoja DR, Kuznetsova SA, Tsokos M, Roberts DD. Endogenous thrombospondin-1 regulates leukocyte recruitment and activation and accelerates death from systemic candidiasis. PLoS One. 2012; 7(11):e48775. PMID: 23144964.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  41. Merchant MS, Geller JI, Baird K, Chou AJ, Galli S, Charles A, Amaoko M, Rhee EH, Price A, Wexler LH, Meyers PA, Widemann BC, Tsokos M, Mackall CL. Phase I trial and pharmacokinetic study of lexatumumab in pediatric patients with solid tumors. J Clin Oncol. 2012 Nov 20; 30(33):4141-7. PMID: 23071222.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  42. Soto-Pantoja DR, Miller TW, Pendrak ML, DeGraff WG, Sullivan C, Ridnour LA, Abu-Asab M, Wink DA, Tsokos M, Roberts DD. CD47 deficiency confers cell and tissue radioprotection by activation of autophagy. Autophagy. 2012 Nov; 8(11):1628-42. PMID: 22874555.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  43. Petrini I, Meltzer PS, Zucali PA, Luo J, Lee C, Santoro A, Lee HS, Killian KJ, Wang Y, Tsokos M, Roncalli M, Steinberg SM, Wang Y, Giaccone G. Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors. Cell Death Dis. 2012 Jul 19; 3:e351. PMID: 22825469.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  44. Gills JJ, Zhang C, Abu-Asab MS, Castillo SS, Marceau C, LoPiccolo J, Kozikowski AP, Tsokos M, Goldkorn T, Dennis PA. Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine. Cell Death Dis. 2012 Jul 05; 3:e340. PMID: 22764099.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  45. Meissner EG, Bennett JE, Qvarnstrom Y, da Silva A, Chu EY, Tsokos M, Gea-Banacloche J. Disseminated microsporidiosis in an immunosuppressed patient. Emerg Infect Dis. 2012 Jul; 18(7):1155-8. PMID: 22709509.
    Citations: 7     Fields:    Translation:HumansAnimals
  46. Stauffer JK, Orentas RJ, Lincoln E, Khan T, Salcedo R, Hixon JA, Back TC, Wei JS, Patidar R, Song Y, Hurd L, Tsokos M, Lai EW, Eisenhofer G, Weiss W, Khan J, Wigginton JM. High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery. Cancer Invest. 2012 Jun; 30(5):343-63. PMID: 22571338.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  47. Meany H, Dombi E, Reynolds J, Whatley M, Kurwa A, Tsokos M, Salzer W, Gillespie A, Baldwin A, Derdak J, Widemann B. 18-fluorodeoxyglucose-positron emission tomography (FDG-PET) evaluation of nodular lesions in patients with Neurofibromatosis type 1 and plexiform neurofibromas (PN) or malignant peripheral nerve sheath tumors (MPNST). Pediatr Blood Cancer. 2013 Jan; 60(1):59-64. PMID: 22645095.
    Citations: 19     Fields:    Translation:Humans
  48. Lai JP, Robbins PF, Raffeld M, Aung PP, Tsokos M, Rosenberg SA, Miettinen MM, Lee CC. NY-ESO-1 expression in synovial sarcoma and other mesenchymal tumors: significance for NY-ESO-1-based targeted therapy and differential diagnosis. Mod Pathol. 2012 Jun; 25(6):854-8. PMID: 22388761.
    Citations: 26     Fields:    Translation:HumansCells
  49. Hejna P, Zátopková L, Tsokos M. The diagnostic value of synovial membrane hemorrhage and bloody discoloration of synovial fluid ("inner knee sign") in autopsy cases of fatal hypothermia. Int J Legal Med. 2012 May; 126(3):415-9. PMID: 22349758.
    Citations: 3     Fields:    Translation:HumansCells
  50. Gochuico BR, Huizing M, Golas GA, Scher CD, Tsokos M, Denver SD, Frei-Jones MJ, Gahl WA. Interstitial lung disease and pulmonary fibrosis in Hermansky-Pudlak syndrome type 2, an adaptor protein-3 complex disease. Mol Med. 2012 Feb 10; 18:56-64. PMID: 22009278.
    Citations: 30     Fields:    Translation:Humans
  51. Tsokos M, Alaggio RD, Dehner LP, Dickman PS. Ewing sarcoma/peripheral primitive neuroectodermal tumor and related tumors. Pediatr Dev Pathol. 2012; 15(1 Suppl):108-26. PMID: 22420726.
    Citations: 15     Fields:    Translation:Humans
  52. Meadors JL, Cui Y, Chen QR, Song YK, Khan J, Merlino G, Tsokos M, Orentas RJ, Mackall CL. Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy. Pediatr Blood Cancer. 2011 Dec 01; 57(6):921-9. PMID: 21462302.
    Citations: 13     Fields:    Translation:AnimalsCells
  53. Rame JE, Barouch LA, Sack MN, Lynn EG, Abu-Asab M, Tsokos M, Kern SJ, Barb JJ, Munson PJ, Halushka MK, Miller KL, Fox-Talbot K, Zhang J, Hare JM, Solomon MA, Danner RL. Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPAR{alpha}/PGC1{alpha} and thermogenic glycerolipid/fatty acid cycling. Physiol Genomics. 2011 Jun 28; 43(12):726-38. PMID: 21427359.
    Citations: 10     Fields:    Translation:Animals
  54. Frazier EP, Isenberg JS, Shiva S, Zhao L, Schlesinger P, Dimitry J, Abu-Asab MS, Tsokos M, Roberts DD, Frazier WA. Age-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47. Matrix Biol. 2011 Mar; 30(2):154-61. PMID: 21256215.
    Citations: 28     Fields:    Translation:AnimalsCells
  55. Yang Y, Valera VA, Padilla-Nash HM, Sourbier C, Vocke CD, Vira MA, Abu-Asab MS, Bratslavsky G, Tsokos M, Merino MJ, Pinto PA, Srinivasan R, Ried T, Neckers L, Linehan WM. UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer. Cancer Genet Cytogenet. 2010 Jan 01; 196(1):45-55. PMID: 19963135.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  56. Maxhimer JB, Soto-Pantoja DR, Ridnour LA, Shih HB, Degraff WG, Tsokos M, Wink DA, Isenberg JS, Roberts DD. Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling. Sci Transl Med. 2009 Oct 21; 1(3):3ra7. PMID: 20161613.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  57. Reid GS, Shan X, Coughlin CM, Lassoued W, Pawel BR, Wexler LH, Thiele CJ, Tsokos M, Pinkus JL, Pinkus GS, Grupp SA, Vonderheide RH. Interferon-gamma-dependent infiltration of human T cells into neuroblastoma tumors in vivo. Clin Cancer Res. 2009 Nov 01; 15(21):6602-8. PMID: 19825945.
    Citations: 8     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  58. Fitzhugh CD, Wise B, Baird K, Tsokos M, Helman L, Mackall C, Savage SA, Warren KE. Secondary supratentorial primitive neuroectodermal tumor following treatment of childhood osteosarcoma. Pediatr Blood Cancer. 2009 Sep; 53(3):496-8. PMID: 19434734.
    Citations:    Fields:    Translation:Humans
  59. Mochel F, Yang B, Barritault J, Thompson JN, Engelke UF, McNeill NH, Benko WS, Kaneski CR, Adams DR, Tsokos M, Abu-Asab M, Huizing M, Seguin F, Wevers RA, Ding J, Verheijen FW, Schiffmann R. Free sialic acid storage disease without sialuria. Ann Neurol. 2009 Jun; 65(6):753-7. PMID: 19557856.
    Citations: 3     Fields:    Translation:Humans
  60. Li Q, Schurgers LJ, Smith AC, Tsokos M, Uitto J, Cowen EW. Co-existent pseudoxanthoma elasticum and vitamin K-dependent coagulation factor deficiency: compound heterozygosity for mutations in the GGCX gene. Am J Pathol. 2009 Feb; 174(2):534-40. PMID: 19116367.
    Citations: 27     Fields:    Translation:HumansCells
  61. Timmers HJ, Pacak K, Huynh TT, Abu-Asab M, Tsokos M, Merino MJ, Baysal BE, Adams KT, Eisenhofer G. Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene. J Clin Endocrinol Metab. 2008 Dec; 93(12):4826-32. PMID: 18840642.
    Citations: 37     Fields:    Translation:Humans
  62. Isenberg JS, Maxhimer JB, Hyodo F, Pendrak ML, Ridnour LA, DeGraff WG, Tsokos M, Wink DA, Roberts DD. Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury. Am J Pathol. 2008 Oct; 173(4):1100-12. PMID: 18787106.
    Citations: 38     Fields:    Translation:AnimalsCellsPHPublic Health
  63. Isenberg JS, Maxhimer JB, Powers P, Tsokos M, Frazier WA, Roberts DD. Treatment of liver ischemia-reperfusion injury by limiting thrombospondin-1/CD47 signaling. Surgery. 2008 Nov; 144(5):752-61. PMID: 19081017.
    Citations: 36     Fields:    Translation:AnimalsCells
  64. Martin-Manso G, Galli S, Ridnour LA, Tsokos M, Wink DA, Roberts DD. Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells. Cancer Res. 2008 Sep 01; 68(17):7090-9. PMID: 18757424.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  65. Mackall CL, Rhee EH, Read EJ, Khuu HM, Leitman SF, Bernstein D, Tesso M, Long LM, Grindler D, Merino M, Kopp W, Tsokos M, Berzofsky JA, Helman LJ. A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas. Clin Cancer Res. 2008 Aug 01; 14(15):4850-8. PMID: 18676758.
    Citations: 50     Fields:    Translation:HumansCells
  66. Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A. 2008 Mar 04; 105(9):3374-9. PMID: 18296641.
    Citations: 439     Fields:    Translation:HumansAnimalsCells
  67. Lodish MB, Powell AC, Abu-Asab M, Cochran C, Lenz P, Libutti SK, Pingpank JF, Tsokos M, Gorden P. Insulinoma and gastrinoma syndromes from a single intrapancreatic neuroendocrine tumor. J Clin Endocrinol Metab. 2008 Apr; 93(4):1123-8. PMID: 18252785.
    Citations: 4     Fields:    Translation:Humans
  68. Alesci S, Abu-Asab M, Perera SM, Tsokos M, Morris JC, Pacak K. Mitochondrial localization of human recombinant adenovirus: from evolution to gene therapy. Neuroimmunomodulation. 2007; 14(5):221-3. PMID: 18219224.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  69. Yang Y, Padilla-Nash HM, Vira MA, Abu-Asab MS, Val D, Worrell R, Tsokos M, Merino MJ, Pavlovich CP, Ried T, Linehan WM, Vocke CD. The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway. Cancer Genet Cytogenet. 2008 Jan 15; 180(2):100-9. PMID: 18206534.
    Citations: 29     Fields:    Translation:HumansCells
  70. Kim SY, Tsokos M, Helman LJ. Dilemmas associated with congenital ewing sarcoma family tumors. J Pediatr Hematol Oncol. 2008 Jan; 30(1):4-7. PMID: 18176172.
    Citations: 3     Fields:    Translation:Humans
  71. Isenberg JS, Pappan LK, Romeo MJ, Abu-Asab M, Tsokos M, Wink DA, Frazier WA, Roberts DD. Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts. Ann Surg. 2008 Jan; 247(1):180-90. PMID: 18156939.
    Citations: 46     Fields:    Translation:Animals
  72. Isenberg JS, Hyodo F, Pappan LK, Abu-Asab M, Tsokos M, Krishna MC, Frazier WA, Roberts DD. Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia. Arterioscler Thromb Vasc Biol. 2007 Dec; 27(12):2582-8. PMID: 17916772.
    Citations: 49     Fields:    Translation:AnimalsCells
  73. Gills JJ, Lopiccolo J, Tsurutani J, Shoemaker RH, Best CJ, Abu-Asab MS, Borojerdi J, Warfel NA, Gardner ER, Danish M, Hollander MC, Kawabata S, Tsokos M, Figg WD, Steeg PS, Dennis PA. Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clin Cancer Res. 2007 Sep 01; 13(17):5183-94. PMID: 17785575.
    Citations: 108     Fields:    Translation:HumansAnimalsCells
  74. Lissat A, Vraetz T, Tsokos M, Klein R, Braun M, Koutelia N, Fisch P, Romero ME, Long L, Noellke P, Mackall CL, Niemeyer CM, Kontny U. Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity. Am J Pathol. 2007 Jun; 170(6):1917-30. PMID: 17525260.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  75. Alesci S, Perera SM, Lai EW, Kukura C, Abu-Asab M, Tsokos M, Morris JC, Pacak K. Adenoviral gene transfer in bovine adrenomedullary and murine pheochromocytoma cells: potential clinical and therapeutic relevance. Endocrinology. 2007 Aug; 148(8):3900-7. PMID: 17525127.
    Citations: 3     Fields:    Translation:AnimalsCells
  76. Ahmed AA, Tsokos M. Sinonasal rhabdomyosarcoma in children and young adults. Int J Surg Pathol. 2007 Apr; 15(2):160-5. PMID: 17478770.
    Citations: 6     Fields:    Translation:Humans
  77. Petricoin EF, Espina V, Araujo RP, Midura B, Yeung C, Wan X, Eichler GS, Johann DJ, Qualman S, Tsokos M, Krishnan K, Helman LJ, Liotta LA. Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res. 2007 Apr 01; 67(7):3431-40. PMID: 17409454.
    Citations: 88     Fields:    Translation:HumansAnimalsCells
  78. Valencia JC, Rouzaud F, Julien S, Chen KG, Passeron T, Yamaguchi Y, Abu-Asab M, Tsokos M, Costin GE, Yamaguchi H, Jenkins LM, Nagashima K, Appella E, Hearing VJ. Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils. J Biol Chem. 2007 Apr 13; 282(15):11266-80. PMID: 17303571.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  79. Isenberg JS, Romeo MJ, Abu-Asab M, Tsokos M, Oldenborg A, Pappan L, Wink DA, Frazier WA, Roberts DD. Increasing survival of ischemic tissue by targeting CD47. Circ Res. 2007 Mar 16; 100(5):712-20. PMID: 17293482.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  80. Steel JC, Cavanagh HM, Burton MA, Abu-Asab MS, Tsokos M, Morris JC, Kalle WH. Increased tumor localization and reduced immune response to adenoviral vector formulated with the liposome DDAB/DOPE. Eur J Pharm Sci. 2007 Apr; 30(5):398-405. PMID: 17275269.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  81. Timmons M, Tsokos M, Asab MA, Seminara SB, Zirzow GC, Kaneski CR, Heiss JD, van der Knaap MS, Vanier MT, Schiffmann R, Wong K. Peripheral and central hypomyelination with hypogonadotropic hypogonadism and hypodontia. Neurology. 2006 Dec 12; 67(11):2066-9. PMID: 17159124.
    Citations: 26     Fields:    Translation:Humans
  82. Isenberg JS, Hyodo F, Matsumoto K, Romeo MJ, Abu-Asab M, Tsokos M, Kuppusamy P, Wink DA, Krishna MC, Roberts DD. Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation. Blood. 2007 Mar 01; 109(5):1945-52. PMID: 17082319.
    Citations: 65     Fields:    Translation:AnimalsCells
  83. Ahmed AA, Nava VE, Pham T, Taubenberger JK, Lichy JH, Sorbara L, Raffeld M, Mackall CL, Tsokos M. Ewing sarcoma family of tumors in unusual sites: confirmation by rt-PCR. Pediatr Dev Pathol. 2006 Nov-Dec; 9(6):488-95. PMID: 17163788.
    Citations: 7     Fields:    Translation:Humans
  84. Michel RB, Abu-Asab M, Tsokos M, Mattes MJ. Characterization of antibody-containing vesicles shed from B-lymphoma cell lines: exposure of annexin V binding sites. Leuk Lymphoma. 2006 Nov; 47(11):2388-99. PMID: 17107914.
    Citations: 2     Fields:    Translation:Cells
  85. Vortmeyer AO, Tran MG, Zeng W, Gläsker S, Riley C, Tsokos M, Ikejiri B, Merrill MJ, Raffeld M, Zhuang Z, Lonser RR, Maxwell PH, Oldfield EH. Evolution of VHL tumourigenesis in nerve root tissue. J Pathol. 2006 Nov; 210(3):374-82. PMID: 16981244.
    Citations: 16     Fields:    Translation:HumansCells
  86. Vishnyakova TG, Kurlander R, Bocharov AV, Baranova IN, Chen Z, Abu-Asab MS, Tsokos M, Malide D, Basso F, Remaley A, Csako G, Eggerman TL, Patterson AP. CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16888-93. PMID: 17071747.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  87. Schinstine M, Abati A, Tsokos M, Fox E, Filie AC. Cytological identification of metastatic epithelial nephroblastoma in pleural fluid: report of a case and review of literature. Diagn Cytopathol. 2006 Sep; 34(9):621-5. PMID: 16900470.
    Citations:    Fields:    Translation:Humans
  88. Ge Y, Montano I, Rustici G, Freebern WJ, Haggerty CM, Cui W, Ponciano-Jackson D, Chandramouli GV, Gardner ER, Figg WD, Abu-Asab M, Tsokos M, Jackson SH, Gardner K. Selective leukemic-cell killing by a novel functional class of thalidomide analogs. Blood. 2006 Dec 15; 108(13):4126-35. PMID: 16940421.
    Citations: 14     Fields:    Translation:HumansCells
  89. Lee B, Galli S, Tsokos M. Sensitive Ewing sarcoma and neuroblastoma cell lines have increased levels of BAD expression and decreased levels of BAR expression compared to resistant cell lines. Cancer Lett. 2007 Mar 08; 247(1):110-4. PMID: 16690206.
    Citations: 2     Fields:    Translation:HumansCells
  90. Schiffmann R, Rapkiewicz A, Abu-Asab M, Ries M, Askari H, Tsokos M, Quezado M. Pathological findings in a patient with Fabry disease who died after 2.5 years of enzyme replacement. Virchows Arch. 2006 Mar; 448(3):337-43. PMID: 16315019.
    Citations: 29     Fields:    Translation:HumansCells
  91. Türk EE, Sperhake JP, Madea B, Preuss J, Tsokos M. Immunohistochemical detection of hemoglobin in frost erythema. Forensic Sci Int. 2006 May 10; 158(2-3):131-4. PMID: 16024200.
    Citations: 5     Fields:    Translation:HumansCells
  92. Helman LJ, Yeung C, Espina V, Eichler G, Krishnan K, Tsokos M, Qualman S, Meyer W, Steinberg S, Petricoin EF, Liotta LA. Proteomic profiling identifies prognostic subsets in Rhabdomyosarcoma (RMS). J Clin Oncol. 2005 Jun; 23(16_suppl):9502. PMID: 27946696.
  93. Nathan PC, Tsokos M, Long L, Bernstein D, Wexler LH, Mackall CL, Helman LJ. Adjuvant chemotherapy for the treatment of advanced pediatric nonrhabdomyosarcoma soft tissue sarcoma: the National Cancer Institute experience. Pediatr Blood Cancer. 2005 May; 44(5):449-54. PMID: 15547929.
    Citations: 1     Fields:    Translation:Humans
  94. Matyakhina L, Freedman RJ, Bourdeau I, Wei MH, Stergiopoulos SG, Chidakel A, Walther M, Abu-Asab M, Tsokos M, Keil M, Toro J, Linehan WM, Stratakis CA. Hereditary leiomyomatosis associated with bilateral, massive, macronodular adrenocortical disease and atypical cushing syndrome: a clinical and molecular genetic investigation. J Clin Endocrinol Metab. 2005 Jun; 90(6):3773-9. PMID: 15741255.
    Citations: 26     Fields:    Translation:HumansCells
  95. Barenboim-Stapleton L, Yang X, Tsokos M, Wigginton JM, Padilla-Nash H, Ried T, Thiele CJ. Pediatric pancreatoblastoma: histopathologic and cytogenetic characterization of tumor and derived cell line. Cancer Genet Cytogenet. 2005 Mar; 157(2):109-17. PMID: 15721631.
    Citations: 4     Fields:    Translation:HumansCells
  96. Merchant MS, Yang X, Melchionda F, Romero M, Klein R, Thiele CJ, Tsokos M, Kontny HU, Mackall CL. Interferon gamma enhances the effectiveness of tumor necrosis factor-related apoptosis-inducing ligand receptor agonists in a xenograft model of Ewing's sarcoma. Cancer Res. 2004 Nov 15; 64(22):8349-56. PMID: 15548704.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  97. Maric I, Bryant R, Abu-Asab M, Cohen JI, Vivero A, Jaffe ES, Raffeld M, Tsokos M, Banks PM, Pittaluga S. Human herpesvirus-6-associated acute lymphadenitis in immunocompetent adults. Mod Pathol. 2004 Nov; 17(11):1427-33. PMID: 15494709.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  98. Türk EE, Tsokos M. Blunt cardiac trauma caused by fatal falls from height: an autopsy-based assessment of the injury pattern. J Trauma. 2004 Aug; 57(2):301-4. PMID: 15345976.
    Citations: 10     Fields:    Translation:Humans
  99. Bossis I, Voutetakis A, Matyakhina L, Pack S, Abu-Asab M, Bourdeau I, Griffin KJ, Courcoutsakis N, Stergiopoulos S, Batista D, Tsokos M, Stratakis CA. A pleiomorphic GH pituitary adenoma from a Carney complex patient displays universal allelic loss at the protein kinase A regulatory subunit 1A (PRKARIA) locus. J Med Genet. 2004 Aug; 41(8):596-600. PMID: 15286154.
    Citations: 10     Fields:    Translation:HumansCells
  100. Cassarino DS, Santi M, Arruda A, Patrocinio R, Tsokos M, Ghatak N, Quezado M. Spinal adrenal cortical adenoma with oncocytic features: report of the first intramedullary case and review of the literature. Int J Surg Pathol. 2004 Jul; 12(3):259-64. PMID: 15306940.
    Citations: 10     Fields:    Translation:HumansCells
  101. Gunther DF, Bourdeau I, Matyakhina L, Cassarino D, Kleiner DE, Griffin K, Courkoutsakis N, Abu-Asab M, Tsokos M, Keil M, Carney JA, Stratakis CA. Cyclical Cushing syndrome presenting in infancy: an early form of primary pigmented nodular adrenocortical disease, or a new entity? J Clin Endocrinol Metab. 2004 Jul; 89(7):3173-82. PMID: 15240590.
    Citations: 31     Fields:    Translation:Humans
  102. Stergiopoulos SG, Abu-Asab MS, Tsokos M, Stratakis CA. Pituitary pathology in Carney complex patients. Pituitary. 2004; 7(2):73-82. PMID: 15761655.
    Citations: 19     Fields:    Translation:Humans
  103. Vaurs-Barriere C, Wong K, Weibel TD, Abu-Asab M, Weiss MD, Kaneski CR, Mixon TH, Bonavita S, Creveaux I, Heiss JD, Tsokos M, Goldin E, Quarles RH, Boespflug-Tanguy O, Schiffmann R. Insertion of mutant proteolipid protein results in missorting of myelin proteins. Ann Neurol. 2003 Dec; 54(6):769-80. PMID: 14681886.
    Citations: 6     Fields:    Translation:HumansCells
  104. Gorlick R, Anderson P, Andrulis I, Arndt C, Beardsley GP, Bernstein M, Bridge J, Cheung NK, Dome JS, Ebb D, Gardner T, Gebhardt M, Grier H, Hansen M, Healey J, Helman L, Hock J, Houghton J, Houghton P, Huvos A, Khanna C, Kieran M, Kleinerman E, Ladanyi M, Lau C, Malkin D, Marina N, Meltzer P, Meyers P, Schofield D, Schwartz C, Smith MA, Toretsky J, Tsokos M, Wexler L, Wigginton J, Withrow S, Schoenfeldt M, Anderson B. Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary. Clin Cancer Res. 2003 Nov 15; 9(15):5442-53. PMID: 14654523.
    Citations: 54     Fields:    Translation:Humans
  105. Tsokos GC, Tsokos M. The TRAIL to arthritis. J Clin Invest. 2003 Nov; 112(9):1315-7. PMID: 14597758.
    Citations: 3     Fields:    Translation:AnimalsCells
  106. Debelenko LV, Arthur DC, Pack SD, Helman LJ, Schrump DS, Tsokos M. Identification of CARS-ALK fusion in primary and metastatic lesions of an inflammatory myofibroblastic tumor. Lab Invest. 2003 Sep; 83(9):1255-65. PMID: 13679433.
    Citations: 25     Fields:    Translation:HumansCells
  107. Krakowiak PA, Wassif CA, Kratz L, Cozma D, Kovárová M, Harris G, Grinberg A, Yang Y, Hunter AG, Tsokos M, Kelley RI, Porter FD. Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency. Hum Mol Genet. 2003 Jul 01; 12(13):1631-41. PMID: 12812989.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  108. Uren A, Merchant MS, Sun CJ, Vitolo MI, Sun Y, Tsokos M, Illei PB, Ladanyi M, Passaniti A, Mackall C, Toretsky JA. Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells. Oncogene. 2003 Apr 17; 22(15):2334-42. PMID: 12700668.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  109. Yang X, Merchant MS, Romero ME, Tsokos M, Wexler LH, Kontny U, Mackall CL, Thiele CJ. Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. Cancer Res. 2003 Mar 01; 63(5):1122-9. PMID: 12615731.
    Citations: 28     Fields:    Translation:HumansCells
  110. Li RM, Mannon RB, Kleiner D, Tsokos M, Bynum M, Kirk AD, Kopp JB. BK virus and SV40 co-infection in polyomavirus nephropathy. Transplantation. 2002 Dec 15; 74(11):1497-504. PMID: 12490781.
    Citations: 24     Fields:    Translation:HumansCells
  111. Tsokos M, Paulsen F. Expression of pulmonary lactoferrin in sudden-onset and slow-onset asthma with fatal outcome. Virchows Arch. 2002 Nov; 441(5):494-9. PMID: 12447681.
    Citations: 3     Fields:    Translation:Humans
  112. Wassif CA, Vied D, Tsokos M, Connor WE, Steiner RD, Porter FD. Cholesterol storage defect in RSH/Smith-Lemli-Opitz syndrome fibroblasts. Mol Genet Metab. 2002 Apr; 75(4):325-34. PMID: 12051964.
    Citations: 14     Fields:    Translation:HumansCells
  113. Dagher R, Long LM, Read EJ, Leitman SF, Carter CS, Tsokos M, Goletz TJ, Avila N, Berzofsky JA, Helman LJ, Mackall CL. Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: an inter-institute NIH study. Med Pediatr Oncol. 2002 Mar; 38(3):158-64. PMID: 11836714.
    Citations: 42     Fields:    Translation:HumansCTClinical Trials
  114. Khanna C, Jaboin JJ, Drakos E, Tsokos M, Thiele CJ. Biologically relevant orthotopic neuroblastoma xenograft models: primary adrenal tumor growth and spontaneous distant metastasis. In Vivo. 2002 Mar-Apr; 16(2):77-85. PMID: 12073775.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  115. Njoku DB, Shrestha S, Soloway R, Duray PR, Tsokos M, Abu-Asab MS, Pohl LR, West AB. Subcellular localization of trifluoroacetylated liver proteins in association with hepatitis following isoflurane. Anesthesiology. 2002 Mar; 96(3):757-61. PMID: 11873055.
    Citations: 4     Fields:    Translation:HumansCells
  116. Tsokos M, Anders S, Paulsen F. Lectin binding patterns of alveolar epithelium and subepithelial seromucous glands of the bronchi in sepsis and controls--an approach to characterize the non-specific immunological response of the human lung to sepsis. Virchows Arch. 2002 Feb; 440(2):181-186. PMID: 11964049.
    Citations: 2     Fields:    Translation:HumansCells
  117. Kogulan PK, Smith M, Seidman J, Chang G, Tsokos M, Lucey D. Malakoplakia involving the abdominal wall, urinary bladder, vagina, and vulva: case report and discussion of malakoplakia-associated bacteria. Int J Gynecol Pathol. 2001 Oct; 20(4):403-6. PMID: 11603228.
    Citations: 2     Fields:    Translation:HumansCells
  118. Gonzalez CE, Lyman CA, Lee S, Del Guercio C, Roilides E, Bacher J, Gehrt A, Feuerstein E, Tsokos M, Walsh TJ. Recombinant human macrophage colony-stimulating factor augments pulmonary host defences against Aspergillus fumigatus. Cytokine. 2001 Jul 21; 15(2):87-95. PMID: 11500084.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  119. Poulaki V, Mitsiades N, Romero ME, Tsokos M. Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2. Cancer Res. 2001 Jun 15; 61(12):4864-72. PMID: 11406564.
    Citations: 16     Fields:    Translation:HumansCells
  120. Tsokos M, Reichelt U, Jung R, Nierhaus A, Püschel K. Interleukin-6 and C-reactive protein serum levels in sepsis-related fatalities during the early postmortem period. Forensic Sci Int. 2001 Jun 01; 119(1):47-56. PMID: 11348793.
    Citations: 16     Fields:    Translation:Humans
  121. Leone A, Mitsiades N, Ward Y, Spinelli B, Poulaki V, Tsokos M, Kelly K. The Gem GTP-binding protein promotes morphological differentiation in neuroblastoma. Oncogene. 2001 May 31; 20(25):3217-25. PMID: 11423971.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  122. Dagher R, Pham TA, Sorbara L, Kumar S, Long L, Bernstein D, Mackall C, Raffeld M, Tsokos M, Helman L. Molecular confirmation of Ewing sarcoma. J Pediatr Hematol Oncol. 2001 May; 23(4):221-4. PMID: 11846300.
    Citations: 14     Fields:    Translation:HumansCells
  123. Tsokos M, Anders S, Paulsen F, Fehlauer F, Püschel K. Comparative evaluation of pulmonary lactoferrin and lysozyme immunoreactivity for the postmortem diagnosis of death due to sepsis. Virchows Arch. 2001 Apr; 438(4):376-81. PMID: 11355172.
    Citations: 1     Fields:    Translation:HumansCells
  124. Gaertner EM, Tsokos M, Derringer GA, Neuhauser TS, Arciero C, Andriko JA. Interdigitating dendritic cell sarcoma. A report of four cases and review of the literature. Am J Clin Pathol. 2001 Apr; 115(4):589-97. PMID: 11293908.
    Citations: 29     Fields:    Translation:HumansCells
  125. Mitsiades N, Poulaki V, Mitsiades C, Tsokos M. Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5. Cancer Res. 2001 Mar 15; 61(6):2704-12. PMID: 11289151.
    Citations: 33     Fields:    Translation:HumansCells
  126. LaVaute T, Smith S, Cooperman S, Iwai K, Land W, Meyron-Holtz E, Drake SK, Miller G, Abu-Asab M, Tsokos M, Switzer R, Grinberg A, Love P, Tresser N, Rouault TA. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet. 2001 Feb; 27(2):209-14. PMID: 11175792.
    Citations: 145     Fields:    Translation:AnimalsCells
  127. Cope JU, Tsokos M, Miller RW. Ewing sarcoma and sinonasal neuroectodermal tumors as second malignant tumors after retinoblastoma and other neoplasms. Med Pediatr Oncol. 2001 Feb; 36(2):290-4. PMID: 11452937.
    Citations: 11     Fields:    Translation:Humans
  128. Mitsiades N, Yu WH, Poulaki V, Tsokos M, Stamenkovic I. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer Res. 2001 Jan 15; 61(2):577-81. PMID: 11212252.
    Citations: 108     Fields:    Translation:HumansCells
  129. Tsokos M, Reichelt U, Nierhaus A, Püschel K. Serum procalcitonin (PCT): a valuable biochemical parameter for the post-mortem diagnosis of sepsis. Int J Legal Med. 2001; 114(4-5):237-43. PMID: 11355402.
    Citations: 11     Fields:    Translation:Humans
  130. Tsokos M, Fehlauer F. Post-mortem markers of sepsis: an immunohistochemical study using VLA-4 (CD49d/CD29) and ICAM-1 (CD54) for the detection of sepsis-induced lung injury. Int J Legal Med. 2001; 114(4-5):291-4. PMID: 11355415.
    Citations: 9     Fields:    Translation:Humans
  131. Kim JS, Pirnia F, Choi YH, Nguyen PM, Knepper B, Tsokos M, Schulte TW, Birrer MJ, Blagosklonny MV, Schaefer O, Mushinski JF, Trepel JB. Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint. Oncogene. 2000 Dec 07; 19(52):6082-90. PMID: 11146561.
    Citations: 5     Fields:    Translation:HumansCells
  132. Hewitt RE, McMarlin A, Kleiner D, Wersto R, Martin P, Tsokos M, Stamp GW, Stetler-Stevenson WG, Tsoskas M. Validation of a model of colon cancer progression. J Pathol. 2000 Dec; 192(4):446-54. PMID: 11113861.
    Citations: 83     Fields:    Translation:AnimalsCells
  133. Kumar S, Perlman E, Harris CA, Raffeld M, Tsokos M. Myogenin is a specific marker for rhabdomyosarcoma: an immunohistochemical study in paraffin-embedded tissues. Mod Pathol. 2000 Sep; 13(9):988-93. PMID: 11007039.
    Citations: 34     Fields:    Translation:Humans
  134. Caffrey M, Braddock DT, Louis JM, Abu-Asab MA, Kingma D, Liotta L, Tsokos M, Tresser N, Pannell LK, Watts N, Steven AC, Simon MN, Stahl SJ, Wingfield PT, Clore GM. Biophysical characterization of gp41 aggregates suggests a model for the molecular mechanism of HIV-associated neurological damage and dementia. J Biol Chem. 2000 Jun 30; 275(26):19877-82. PMID: 10747981.
    Citations: 8     Fields:    Translation:HumansCells
  135. Wexler LH, Meyer WH, Parham DM, Tsokos M. Neural differentiation and prognosis in peripheral primitive neuroectodermal tumor. J Clin Oncol. 2000 May; 18(10):2187-8. PMID: 10811686.
    Citations: 2     Fields:    Translation:Humans
  136. Bornstein SR, Abu-Asab M, Glasow A, Päth G, Hauner H, Tsokos M, Chrousos GP, Scherbaum WA. Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture. Diabetes. 2000 Apr; 49(4):532-8. PMID: 10871189.
    Citations: 32     Fields:    Translation:HumansCells
  137. Cope JU, Tsokos M, Helman LJ, Gridley G, Tucker MA. Inguinal hernia in patients with Ewing sarcoma: a clue to etiology. Med Pediatr Oncol. 2000 Mar; 34(3):195-9. PMID: 10696126.
    Citations: 4     Fields:    Translation:Humans
  138. Kruger EA, Duray PH, Tsokos MG, Venzon DJ, Libutti SK, Dixon SC, Rudek MA, Pluda J, Allegra C, Figg WD. Endostatin inhibits microvessel formation in the ex vivo rat aortic ring angiogenesis assay. Biochem Biophys Res Commun. 2000 Feb 05; 268(1):183-91. PMID: 10652234.
    Citations: 22     Fields:    Translation:HumansAnimals
  139. Orban Z, Mitsiades N, Burke TR, Tsokos M, Chrousos GP. Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation. Neuroimmunomodulation. 2000; 7(2):99-105. PMID: 10686520.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  140. Khanna C, Prehn J, Yeung C, Caylor J, Tsokos M, Helman L. An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential. Clin Exp Metastasis. 2000; 18(3):261-71. PMID: 11315100.
    Citations: 78     Fields:    Translation:Animals
  141. Tsokos M, Fehlauer F, Püschel K. Immunohistochemical expression of E-selectin in sepsis-induced lung injury. Int J Legal Med. 2000; 113(6):338-42. PMID: 11100428.
    Citations: 7     Fields:    Translation:Humans
  142. Lubensky IA, Schiffmann R, Goldin E, Tsokos M. Lysosomal inclusions in gastric parietal cells in mucolipidosis type IV: a novel cause of achlorhydria and hypergastrinemia. Am J Surg Pathol. 1999 Dec; 23(12):1527-31. PMID: 10584706.
    Citations: 10     Fields:    Translation:HumansCells
  143. Kumar S, Perlman E, Pack S, Davis M, Zhang H, Meltzer P, Tsokos M. Absence of EWS/FLI1 fusion in olfactory neuroblastomas indicates these tumors do not belong to the Ewing's sarcoma family. Hum Pathol. 1999 Nov; 30(11):1356-60. PMID: 10571517.
    Citations: 4     Fields:    Translation:Humans
  144. Mitsiades N, Poulaki V, Leone A, Tsokos M. Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors. J Natl Cancer Inst. 1999 Oct 06; 91(19):1678-84. PMID: 10511596.
    Citations: 7     Fields:    Translation:HumansCells
  145. Koski GK, Schwartz GN, Weng DE, Gress RE, Engels FH, Tsokos M, Czerniecki BJ, Cohen PA. Calcium ionophore-treated myeloid cells acquire many dendritic cell characteristics independent of prior differentiation state, transformation status, or sensitivity to biologic agents. Blood. 1999 Aug 15; 94(4):1359-71. PMID: 10438724.
    Citations: 16     Fields:    Translation:HumansCells
  146. Parham DM, Hijazi Y, Steinberg SM, Meyer WH, Horowitz M, Tzen CY, Wexler LH, Tsokos M. Neuroectodermal differentiation in Ewing's sarcoma family of tumors does not predict tumor behavior. Hum Pathol. 1999 Aug; 30(8):911-8. PMID: 10452503.
    Citations: 14     Fields:    Translation:Humans
  147. Mitsiades N, Poulaki V, Mastorakos G, Tseleni-Balafouta ST, Kotoula V, Koutras DA, Tsokos M. Fas ligand expression in thyroid carcinomas: a potential mechanism of immune evasion. J Clin Endocrinol Metab. 1999 Aug; 84(8):2924-32. PMID: 10443700.
    Citations: 12     Fields:    Translation:HumansCells
  148. Bar-Ner M, Thibault A, Tsokos M, Magrath IT, Samid D. Phenylbutyrate induces cell differentiation and modulates Epstein-Barr virus gene expression in Burkitt's lymphoma cells. Clin Cancer Res. 1999 Jun; 5(6):1509-16. PMID: 10389940.
    Citations: 6     Fields:    Translation:HumansCells
  149. Kouraklis G, Triche TJ, Wesley R, Tsokos M. Myc oncogene expression and nude mouse tumorigenicity and metastasis formation are higher in alveolar than embryonal rhabdomyosarcoma cell lines. Pediatr Res. 1999 Apr; 45(4 Pt 1):552-8. PMID: 10203148.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  150. Kumar S, Pack S, Kumar D, Walker R, Quezado M, Zhuang Z, Meltzer P, Tsokos M. Detection of EWS-FLI-1 fusion in Ewing's sarcoma/peripheral primitive neuroectodermal tumor by fluorescence in situ hybridization using formalin-fixed paraffin-embedded tissue. Hum Pathol. 1999 Mar; 30(3):324-30. PMID: 10088552.
    Citations: 7     Fields:    Translation:Humans
  151. Samuel DP, Tsokos M, DeBaun MR. Hemihypertrophy and a poorly differentiated embryonal rhabdomyosarcoma of the pelvis. Med Pediatr Oncol. 1999 Jan; 32(1):38-43. PMID: 9917751.
    Citations: 3     Fields:    Translation:HumansCells
  152. Püschel K, Schulz F, Darrmann I, Tsokos M. Macromorphology and histology of intramuscular hemorrhages in cases of drowning. Int J Legal Med. 1999; 112(2):101-6. PMID: 10048667.
    Citations: 6     Fields:    Translation:Humans
  153. Fidelia-Lambert MN, Zhuang Z, Tsokos M. Sensitive detection of rare Ewing's sarcoma cells in peripheral blood by reverse transcriptase polymerase chain reaction. Hum Pathol. 1999 Jan; 30(1):78-80. PMID: 9923931.
    Citations: 1     Fields:    Translation:HumansCells
  154. Mitsiades N, Poulaki V, Kotoula V, Leone A, Tsokos M. Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase. Am J Pathol. 1998 Dec; 153(6):1947-56. PMID: 9846984.
    Citations: 10     Fields:    Translation:HumansCells
  155. Weil RJ, Huang S, Pack S, Vortmeyer AO, Tsokos M, Lubensky IA, Oldfield EH, Zhuang Z. Pluripotent tumor cells in benign pituitary adenomas associated with multiple endocrine neoplasia type 1. Cancer Res. 1998 Oct 15; 58(20):4715-20. PMID: 9788627.
    Citations: 1     Fields:    Translation:HumansCells
  156. Andriko JW, Kaldjian EP, Tsokos M, Abbondanzo SL, Jaffe ES. Reticulum cell neoplasms of lymph nodes: a clinicopathologic study of 11 cases with recognition of a new subtype derived from fibroblastic reticular cells. Am J Surg Pathol. 1998 Sep; 22(9):1048-58. PMID: 9737236.
    Citations: 18     Fields:    Translation:HumansCells
  157. Butler AA, Blakesley VA, Poulaki V, Tsokos M, Wood TL, LeRoith D, Pouliki V. Stimulation of tumor growth by recombinant human insulin-like growth factor-I (IGF-I) is dependent on the dose and the level of IGF-I receptor expression. Cancer Res. 1998 Jul 15; 58(14):3021-7. PMID: 9679966.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  158. Mitsiades N, Poulaki V, Kotoula V, Mastorakos G, Tseleni-Balafouta S, Koutras DA, Tsokos M. Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis. J Clin Endocrinol Metab. 1998 Jun; 83(6):2199-203. PMID: 9626160.
    Citations: 7     Fields:    Translation:Humans
  159. Bornstein SR, Webster EL, Torpy DJ, Richman SJ, Mitsiades N, Igel M, Lewis DB, Rice KC, Joost HG, Tsokos M, Chrousos GP. Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation. Endocrinology. 1998 Apr; 139(4):1546-55. PMID: 9528933.
    Citations: 19     Fields:    Translation:Animals
  160. Schiffmann R, Dwyer NK, Lubensky IA, Tsokos M, Sutliff VE, Latimer JS, Frei KP, Brady RO, Barton NW, Blanchette-Mackie EJ, Goldin E. Constitutive achlorhydria in mucolipidosis type IV. Proc Natl Acad Sci U S A. 1998 Feb 03; 95(3):1207-12. PMID: 9448310.
    Citations: 26     Fields:    Translation:HumansCells
  161. Quezado M, Benjamin DR, Tsokos M. EWS/FLI-1 fusion transcripts in three peripheral primitive neuroectodermal tumors of the kidney. Hum Pathol. 1997 Jul; 28(7):767-71. PMID: 9224742.
    Citations: 10     Fields:    Translation:Humans
  162. Beckner ME, Krutzsch HC, Tsokos M, Moul DE, Liotta LA. The aggregated form of an AAMP derived peptide behaves as a heparin sensitive cell binding agent. Biotechnol Bioeng. 1997 May 20; 54(4):365-72. PMID: 18634104.
    Citations:    Fields:    
  163. Katz RL, Quezado M, Senderowicz AM, Villalba L, Laskin WB, Tsokos M. An intra-abdominal small round cell neoplasm with features of primitive neuroectodermal and desmoplastic round cell tumor and a EWS/FLI-1 fusion transcript. Hum Pathol. 1997 Apr; 28(4):502-9. PMID: 9104953.
    Citations: 8     Fields:    Translation:Humans
  164. Kleiner DE, Gaffey MJ, Sallie R, Tsokos M, Nichols L, McKenzie R, Straus SE, Hoofnagle JH. Histopathologic changes associated with fialuridine hepatotoxicity. Mod Pathol. 1997 Mar; 10(3):192-9. PMID: 9071726.
    Citations: 10     Fields:    Translation:Humans