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Chengxin Zhou, Ph.D.

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Biography
2015
ARVO Annual Meeting 2015 Travel Grant

Overview
Chengxin Zhou received his PhD degree in Biomedical Engineering from University of Texas Southwestern Medical Center in 2013. During his doctoral study, he investigated key mechanisms for corneal keratocyte migration, and extracellular matrix remodeling using in vivo and in vitro corneal wound healing models. His research also encompassed cellular biomechanics, cell force monitoring, biologic imaging, corneal tissue engineering. He also received Master of Science degree in Biomedical Engineering from Wayne State University in 2008.

In 2014, he started his research fellowship in Boston Keratoprosthesis Lab. His current projects focus on ophthalmic drug delivery device, ocular chemical burn, and keratoprosthesis.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lei F, Cui N, Zhou C, Chodosh J, Vavvas DG, Paschalis EI. CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages. Proc Natl Acad Sci U S A. 2020 Sep 22; 117(38):23336-23338. PMID: 32900927.
    Citations:    
  2. Chen X, Lei F, Zhou C, Chodosh J, Wang L, Huang Y, Dohlman CH, Paschalis EI. Glaucoma after Ocular Surgery or Trauma: The Role of Infiltrating Monocytes and Their Response to Cytokine Inhibitors. Am J Pathol. 2020 Oct; 190(10):2056-2066. PMID: 32693061.
    Citations:    
  3. Zhou C, Singh A, Qian G, Wolkow N, Dohlman CH, Vavvas DG, Chodosh J, Paschalis EI. Microporous Drug Delivery System for Sustained Anti-VEGF Delivery to the Eye. Transl Vis Sci Technol. 2020 Jul; 9(8):5. PMID: 32855852.
    Citations:    
  4. Hui PC, Shtyrkova K, Zhou C, Chen X, Chodosh J, Dohlman CH, Paschalis EI. Implantable self-aligning fiber-optic optomechanical devices for in vivo intraocular pressure-sensing in artificial cornea. J Biophotonics. 2020 Jul; 13(7):e202000031. PMID: 32246524.
    Citations:    
  5. Dohlman CH, Zhou C, Lei F, Cade F, Regatieri CV, Crnej A, Dohlman JG, Shen LQ, Paschalis EI. Glaucoma After Corneal Trauma or Surgery-A Rapid, Inflammatory, IOP-Independent Pathway. Cornea. 2019 Dec; 38(12):1589-1594. PMID: 31453878.
    Citations:    
  6. Paschalis EI, Lei F, Zhou C, Chen XN, Kapoulea V, Hui PC, Dana R, Chodosh J, Vavvas DG, Dohlman CH. Microglia Regulate Neuroglia Remodeling in Various Ocular and Retinal Injuries. J Immunol. 2019 01 15; 202(2):539-549. PMID: 30541880.
    Citations:    Fields:    
  7. Paschalis EI, Lei F, Zhou C, Kapoulea V, Dana R, Chodosh J, Vavvas DG, Dohlman CH. Permanent neuroglial remodeling of the retina following infiltration of CSF1R inhibition-resistant peripheral monocytes. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):E11359-E11368. PMID: 30442669.
    Citations:    Fields:    
  8. Paschalis EI, Lei F, Zhou C, Kapoulea V, Thanos A, Dana R, Vavvas DG, Chodosh J, Dohlman CH. The Role of Microglia and Peripheral Monocytes in Retinal Damage after Corneal Chemical Injury. Am J Pathol. 2018 07; 188(7):1580-1596. PMID: 29630857.
    Citations:    Fields:    
  9. Dohlman CH, Cade F, Regatieri CV, Zhou C, Lei F, Crnej A, Harissi-Dagher M, Robert MC, Papaliodis GN, Chen D, Aquavella JV, Akpek EK, Aldave AJ, Sippel KC, D'Amico DJ, Dohlman JG, Fagerholm P, Wang L, Shen LQ, González-Andrades M, Chodosh J, Kenyon KR, Foster CS, Pineda R, Melki S, Colby KA, Ciolino JB, Vavvas DG, Kinoshita S, Dana R, Paschalis EI. Chemical Burns of the Eye: The Role of Retinal Injury and New Therapeutic Possibilities. Cornea. 2018 Feb; 37(2):248-251. PMID: 29135604.
    Citations: 1     Fields:    Translation:Humans
  10. Paschalis EI, Zhou C, Lei F, Scott N, Kapoulea V, Robert MC, Vavvas D, Dana R, Chodosh J, Dohlman CH. Mechanisms of Retinal Damage after Ocular Alkali Burns. Am J Pathol. 2017 Jun; 187(6):1327-1342. PMID: 28412300.
    Citations: 1     Fields:    Translation:AnimalsCells
  11. Zhou C, Robert MC, Kapoulea V, Lei F, Stagner AM, Jakobiec FA, Dohlman CH, Paschalis EI. Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye. Invest Ophthalmol Vis Sci. 2017 01 01; 58(1):96-105. PMID: 28114570.
    Citations: 4     Fields:    Translation:Animals
  12. Zhou C, Lei F, Chodosh J, Paschalis EI. The Role of Titanium Surface Microtopography on Adhesion, Proliferation, Transformation, and Matrix Deposition of Corneal Cells. Invest Ophthalmol Vis Sci. 2016 Apr 01; 57(4):1927-38. PMID: 27092719.
    Citations: 1     Fields:    Translation:HumansCells
  13. Robert MC, Frenette M, Zhou C, Yan Y, Chodosh J, Jakobiec FA, Stagner AM, Vavvas D, Dohlman CH, Paschalis EI. A Drug Delivery System for Administration of Anti-TNF-a Antibody. Transl Vis Sci Technol. 2016 Mar; 5(2):11. PMID: 26981333.
    Citations: 3     
  14. Zhou C, Petroll WM. MMP regulation of corneal keratocyte motility and mechanics in 3-D collagen matrices. Exp Eye Res. 2014 Apr; 121:147-60. PMID: 24530619.
    Citations: 5     Fields:    Translation:AnimalsCells
  15. Miron-Mendoza M, Koppaka V, Zhou C, Petroll WM. Techniques for assessing 3-D cell-matrix mechanical interactions in vitro and in vivo. Exp Cell Res. 2013 Oct 01; 319(16):2470-80. PMID: 23819988.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  16. Kim A, Zhou C, Lakshman N, Petroll WM. Corneal stromal cells use both high- and low-contractility migration mechanisms in 3-D collagen matrices. Exp Cell Res. 2012 Apr 01; 318(6):741-52. PMID: 22233682.
    Citations: 15     Fields:    Translation:AnimalsCells
  17. Zhou C, Petroll WM. Rho Kinase Regulation of Fibroblast Migratory Mechanics in Fibrillar Collagen Matrices. Cell Mol Bioeng. 2010 Mar 01; 3(1):76-83. PMID: 21132118.
    Citations: 9     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.