Harvard Catalyst Profiles

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Chia Yu Wang, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang CY, Xiao X, Bayer A, Xu Y, Dev S, Canali S, Nair AV, Masia R, Babitt JL. Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice. Hepatology. 2019 12; 70(6):1986-2002. PMID: 31127639.
    Citations:    
  2. Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H. Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin. Nat Metab. 2019 May; 1(5):519-531. PMID: 31276102.
    Citations:    
  3. Wang CY, Canali S, Bayer A, Dev S, Agarwal A, Babitt JL. Iron, erythropoietin, and inflammation regulate hepcidin in Bmp2-deficient mice, but serum iron fails to induce hepcidin in Bmp6-deficient mice. Am J Hematol. 2019 02; 94(2):240-248. PMID: 30478858.
    Citations:    Fields:    
  4. Wang CY, Babitt JL. Liver iron sensing and body iron homeostasis. Blood. 2019 01 03; 133(1):18-29. PMID: 30401708.
    Citations:    Fields:    
  5. Merkulova M, Paunescu TG, Nair AV, Wang CY, Capen DE, Oliver PL, Breton S, Brown D. Targeted deletion of the Ncoa7 gene results in incomplete distal renal tubular acidosis in mice. Am J Physiol Renal Physiol. 2018 07 01; 315(1):F173-F185. PMID: 29384414.
    Citations:    Fields:    
  6. La A, Nguyen T, Tran K, Sauble E, Tu D, Gonzalez A, Kidane TZ, Soriano C, Morgan J, Doan M, Tran K, Wang CY, Knutson MD, Linder MC. Mobilization of iron from ferritin: new steps and details. Metallomics. 2018 01 24; 10(1):154-168. PMID: 29260183.
    Citations:    
  7. He Q, Bouley R, Liu Z, Wein MN, Zhu Y, Spatz JM, Wang CY, Divieti Pajevic P, Plagge A, Babitt JL, Bastepe M. Large G protein a-subunit XLas limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo. Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9559-E9568. PMID: 29078380.
    Citations:    Fields:    Translation:HumansAnimalsCells
  8. Canali S, Wang CY, Zumbrennen-Bullough KB, Bayer A, Babitt JL. Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6. Am J Hematol. 2017 Nov; 92(11):1204-1213. PMID: 28815688.
    Citations: 4     Fields:    Translation:AnimalsCells
  9. Wang CY, Core AB, Canali S, Zumbrennen-Bullough KB, Ozer S, Umans L, Zwijsen A, Babitt JL. Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice. Blood. 2017 07 06; 130(1):73-83. PMID: 28438754.
    Citations: 4     Fields:    Translation:AnimalsCells
  10. Canali S, Zumbrennen-Bullough KB, Core AB, Wang CY, Nairz M, Bouley R, Swirski FK, Babitt JL. Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice. Blood. 2017 01 26; 129(4):405-414. PMID: 27864295.
    Citations: 20     Fields:    Translation:AnimalsCells
  11. Jenkitkasemwong S, Wang CY, Knutson MD. Measurement of Transferrin- and Non-transferrin-bound Iron Uptake by Mouse Tissues. Bio Protoc. 2016 Sep 05; 6(17). PMID: 28573162.
    Citations:    
  12. Wang CY, Babitt JL. Hepcidin regulation in the anemia of inflammation. Curr Opin Hematol. 2016 May; 23(3):189-97. PMID: 26886082.
    Citations: 15     Fields:    Translation:Humans
  13. Canali S, Core AB, Zumbrennen-Bullough KB, Merkulova M, Wang CY, Schneyer AL, Pietrangelo A, Babitt JL. Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice. Endocrinology. 2016 Mar; 157(3):1146-62. PMID: 26735394.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  14. Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H. Impaired hepcidin expression in alpha-1-antitrypsin deficiency associated with iron overload and progressive liver disease. Hum Mol Genet. 2015 Nov 01; 24(21):6254-63. PMID: 26310624.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  15. Jenkitkasemwong S, Wang CY, Coffey R, Zhang W, Chan A, Biel T, Kim JS, Hojyo S, Fukada T, Knutson MD. SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis. Cell Metab. 2015 Jul 07; 22(1):138-50. PMID: 26028554.
    Citations:    
  16. Wang CY, Meynard D, Lin HY. The role of TMPRSS6/matriptase-2 in iron regulation and anemia. Front Pharmacol. 2014; 5:114. PMID: 24966834.
    Citations: 8     
  17. Wang CY, Knutson MD. Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin-bound iron uptake in mice. Hepatology. 2013 Aug; 58(2):788-98. PMID: 23508576.
    Citations:    
  18. Guo X, Zhang Z, Zhang F, Tao Y, An P, Wu Q, Wang CY, Knutson MD, Wang F. Fine-mapping and genetic analysis of the loci affecting hepatic iron overload in mice. PLoS One. 2013; 8(5):e63280. PMID: 23675470.
    Citations:    
  19. Nam H, Wang CY, Zhang L, Zhang W, Hojyo S, Fukada T, Knutson MD. ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders. Haematologica. 2013 Jul; 98(7):1049-57. PMID: 23349308.
    Citations:    
  20. Wang CY, Jenkitkasemwong S, Duarte S, Sparkman BK, Shawki A, Mackenzie B, Knutson MD. ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading. J Biol Chem. 2012 Oct 05; 287(41):34032-43. PMID: 22898811.
    Citations:    
  21. Jenkitkasemwong S, Wang CY, Mackenzie B, Knutson MD. Physiologic implications of metal-ion transport by ZIP14 and ZIP8. Biometals. 2012 Aug; 25(4):643-55. PMID: 22318508.
    Citations:    
  22. Lyu LC, Lo CC, Chen HF, Wang CY, Liu DM. A prospective study of dietary intakes and influential factors from pregnancy to postpartum on maternal weight retention in Taipei, Taiwan. Br J Nutr. 2009 Dec; 102(12):1828-37. PMID: 19678967.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.